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Items: 1 to 50 of 68

1.

Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunity.

Dittmer U, Sutter K, Kassiotis G, Zelinskyy G, Bánki Z, Stoiber H, Santiago ML, Hasenkrug KJ.

FEMS Microbiol Rev. 2019 May 14. pii: fuz012. doi: 10.1093/femsre/fuz012. [Epub ahead of print]

PMID:
31087035
2.

MHC class II cell-autonomously regulates self-renewal and differentiation of normal and malignant B cells.

Merkenschlager J, Eksmond U, Danelli L, Attig J, Young GR, Nowosad C, Tolar P, Kassiotis G.

Blood. 2019 Mar 7;133(10):1108-1118. doi: 10.1182/blood-2018-11-885467. Epub 2019 Jan 30.

PMID:
30700420
3.

A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus.

Uchil PD, Pi R, Haugh KA, Ladinsky MS, Ventura JD, Barrett BS, Santiago ML, Bjorkman PJ, Kassiotis G, Sewald X, Mothes W.

Cell Host Microbe. 2019 Jan 9;25(1):87-100.e10. doi: 10.1016/j.chom.2018.11.011. Epub 2018 Dec 27.

4.

Restoration of Endogenous Retrovirus Infectivity Impacts Mouse Cancer Models.

Ottina E, Levy P, Eksmond U, Merkenschlager J, Young GR, Roels J, Stoye JP, Tüting T, Calado DP, Kassiotis G.

Cancer Immunol Res. 2018 Nov;6(11):1292-1300. doi: 10.1158/2326-6066.CIR-18-0038. Epub 2018 Aug 24.

5.

Correlates of Follicular Helper Bias in the CD4 T Cell Response to a Retroviral Antigen.

Danelli L, Donnarumma T, Kassiotis G.

Front Immunol. 2018 Jun 5;9:1260. doi: 10.3389/fimmu.2018.01260. eCollection 2018.

6.

Physiological and Pathological Transcriptional Activation of Endogenous Retroelements Assessed by RNA-Sequencing of B Lymphocytes.

Attig J, Young GR, Stoye JP, Kassiotis G.

Front Microbiol. 2017 Dec 12;8:2489. doi: 10.3389/fmicb.2017.02489. eCollection 2017.

7.

Regulatory T cells constrain the TCR repertoire of antigen-stimulated conventional CD4 T cells.

Fontaine M, Vogel I, Van Eycke YR, Galuppo A, Ajouaou Y, Decaestecker C, Kassiotis G, Moser M, Leo O.

EMBO J. 2018 Feb 1;37(3):398-412. doi: 10.15252/embj.201796881. Epub 2017 Dec 20.

8.

Making a virtue of necessity: the pleiotropic role of human endogenous retroviruses in cancer.

Kassiotis G, Stoye JP.

Philos Trans R Soc Lond B Biol Sci. 2017 Oct 19;372(1732). pii: 20160277. doi: 10.1098/rstb.2016.0277. Review.

9.

Mutation of the Putative Immunosuppressive Domain of the Retroviral Envelope Glycoprotein Compromises Infectivity.

Eksmond U, Jenkins B, Merkenschlager J, Mothes W, Stoye JP, Kassiotis G.

J Virol. 2017 Oct 13;91(21). pii: e01152-17. doi: 10.1128/JVI.01152-17. Print 2017 Nov 1.

10.

Antigenicity of peptides comprising the immunosuppressive domain of the retroviral envelope glycoprotein.

Jenkins B, Eksmond U, Young G, Kassiotis G.

Wellcome Open Res. 2016 Dec 6;1:22. doi: 10.12688/wellcomeopenres.10269.2.

11.

Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus.

Donnarumma T, Young GR, Merkenschlager J, Eksmond U, Bongard N, Nutt SL, Boyer C, Dittmer U, Le-Trilling VT, Trilling M, Bayer W, Kassiotis G.

Cell Rep. 2016 Nov 1;17(6):1571-1583. doi: 10.1016/j.celrep.2016.10.013.

12.

Dichotomy between T Cell and B Cell Tolerance to Neonatal Retroviral Infection Permits T Cell Therapy.

Mavrommatis B, Baudino L, Levy P, Merkenschlager J, Eksmond U, Donnarumma T, Young G, Stoye J, Kassiotis G.

J Immunol. 2016 Nov 1;197(9):3628-3638. Epub 2016 Sep 19.

13.

Immune responses to endogenous retroelements: taking the bad with the good.

Kassiotis G, Stoye JP.

Nat Rev Immunol. 2016 Apr;16(4):207-19. doi: 10.1038/nri.2016.27. Review.

PMID:
27026073
14.

Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.

Li SX, Barrett BS, Guo K, Kassiotis G, Hasenkrug KJ, Dittmer U, Gibbert K, Santiago ML.

Sci Rep. 2016 Feb 5;6:20425. doi: 10.1038/srep20425.

15.

Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response.

Merkenschlager J, Ploquin MJ, Eksmond U, Andargachew R, Thorborn G, Filby A, Pepper M, Evavold B, Kassiotis G.

Nat Commun. 2016 Jan 5;7:10281. doi: 10.1038/ncomms10281.

16.

Narrowing the Gap: Preserving Repertoire Diversity Despite Clonal Selection during the CD4 T Cell Response.

Merkenschlager J, Kassiotis G.

Front Immunol. 2015 Aug 11;6:413. doi: 10.3389/fimmu.2015.00413. eCollection 2015. Review.

17.

Microarray analysis reveals global modulation of endogenous retroelement transcription by microbes.

Young GR, Mavrommatis B, Kassiotis G.

Retrovirology. 2014 Jul 25;11:59. doi: 10.1186/1742-4690-11-59.

18.

Clonotypic composition of the CD4+ T cell response to a vectored retroviral antigen is determined by its speed.

Thorborn G, Ploquin MJ, Eksmond U, Pike R, Bayer W, Dittmer U, Hasenkrug KJ, Pepper M, Kassiotis G.

J Immunol. 2014 Aug 15;193(4):1567-77. doi: 10.4049/jimmunol.1400667. Epub 2014 Jul 7.

19.

Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo.

Li SX, Barrett BS, Heilman KJ, Messer RJ, Liberatore RA, Bieniasz PD, Kassiotis G, Hasenkrug KJ, Santiago ML.

J Immunol. 2014 Jul 1;193(1):306-16. doi: 10.4049/jimmunol.1400490. Epub 2014 May 28.

20.

Effective T helper cell responses against retroviruses: are all clonotypes equal?

Thorborn G, Young GR, Kassiotis G.

J Leukoc Biol. 2014 Jul;96(1):27-37. doi: 10.1189/jlb.2RI0613-347R. Epub 2014 Apr 15. Review.

PMID:
24737804
21.

Endogenous retroviruses and the development of cancer.

Kassiotis G.

J Immunol. 2014 Feb 15;192(4):1343-9. doi: 10.4049/jimmunol.1302972. Review.

22.

Recovery of an antiviral antibody response following attrition caused by unrelated infection.

Ng DH, Skehel JJ, Kassiotis G, Langhorne J.

PLoS Pathog. 2014 Jan;10(1):e1003843. doi: 10.1371/journal.ppat.1003843. Epub 2014 Jan 2.

23.

Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis.

Young GR, Stoye JP, Kassiotis G.

Bioessays. 2013 Sep;35(9):794-803. doi: 10.1002/bies.201300049. Epub 2013 Jul 17. Review.

24.

Counterpoise between the microbiome, host immune activation and pathology.

Mavrommatis B, Young GR, Kassiotis G.

Curr Opin Immunol. 2013 Aug;25(4):456-62. doi: 10.1016/j.coi.2013.05.009. Epub 2013 Jun 4. Review.

25.

IL-2-independent and TNF-α-dependent expansion of Vβ5+ natural regulatory T cells during retrovirus infection.

Myers L, Joedicke JJ, Carmody AB, Messer RJ, Kassiotis G, Dudley JP, Dittmer U, Hasenkrug KJ.

J Immunol. 2013 Jun 1;190(11):5485-95. doi: 10.4049/jimmunol.1202951. Epub 2013 May 3.

26.

Resurrection of endogenous retroviruses in antibody-deficient mice.

Young GR, Eksmond U, Salcedo R, Alexopoulou L, Stoye JP, Kassiotis G.

Nature. 2012 Nov 29;491(7426):774-8. doi: 10.1038/nature11599. Epub 2012 Oct 24.

27.

Negative impact of IFN-γ on early host immune responses to retroviral infection.

Duley AK, Ploquin MJ, Eksmond U, Ammann CG, Messer RJ, Myers L, Hasenkrug KJ, Kassiotis G.

J Immunol. 2012 Sep 1;189(5):2521-9. doi: 10.4049/jimmunol.1201125. Epub 2012 Jul 20.

28.

Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection.

Young GR, Ploquin MJ, Eksmond U, Wadwa M, Stoye JP, Kassiotis G.

PLoS Pathog. 2012;8(5):e1002709. doi: 10.1371/journal.ppat.1002709. Epub 2012 May 10.

29.

Emv2, the only endogenous ecotropic murine leukemia virus of C57BL/6J mice.

Young GR, Kassiotis G, Stoye JP.

Retrovirology. 2012 Mar 22;9:23. doi: 10.1186/1742-4690-9-23.

30.

Distinct roles of CD4+ T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse model.

Nair S, Bayer W, Ploquin MJ, Kassiotis G, Hasenkrug KJ, Dittmer U.

Retrovirology. 2011 Sep 26;8:76. doi: 10.1186/1742-4690-8-76. Review.

31.

B cells and TCR avidity determine distinct functions of CD4+ T cells in retroviral infection.

Ploquin MJ, Eksmond U, Kassiotis G.

J Immunol. 2011 Sep 15;187(6):3321-30. doi: 10.4049/jimmunol.1101006. Epub 2011 Aug 12.

32.

Suppression of innate immune pathology by regulatory T cells during Influenza A virus infection of immunodeficient mice.

Antunes I, Kassiotis G.

J Virol. 2010 Dec;84(24):12564-75. doi: 10.1128/JVI.01559-10. Epub 2010 Oct 13.

33.

Generalized immune activation as a direct result of activated CD4+ T cell killing.

Marques R, Williams A, Eksmond U, Wullaert A, Killeen N, Pasparakis M, Kioussis D, Kassiotis G.

J Biol. 2009;8(10):93. doi: 10.1186/jbiol194.

34.

Mechanisms of control of acute Friend virus infection by CD4+ T helper cells and their functional impairment by regulatory T cells.

Nair SR, Zelinskyy G, Schimmer S, Gerlach N, Kassiotis G, Dittmer U.

J Gen Virol. 2010 Feb;91(Pt 2):440-51. doi: 10.1099/vir.0.015834-0. Epub 2009 Oct 14.

PMID:
19828756
35.

Establishing the follicular helper identity.

Kassiotis G, O'Garra A.

Immunity. 2009 Sep 18;31(3):450-2. doi: 10.1016/j.immuni.2009.08.017.

36.

Race between retroviral spread and CD4+ T-cell response determines the outcome of acute Friend virus infection.

Pike R, Filby A, Ploquin MJ, Eksmond U, Marques R, Antunes I, Hasenkrug K, Kassiotis G.

J Virol. 2009 Nov;83(21):11211-22. doi: 10.1128/JVI.01225-09. Epub 2009 Aug 19.

37.

Retrovirus-specificity of regulatory T cells is neither present nor required in preventing retrovirus-induced bone marrow immune pathology.

Antunes I, Tolaini M, Kissenpfennig A, Iwashiro M, Kuribayashi K, Malissen B, Hasenkrug K, Kassiotis G.

Immunity. 2008 Nov 14;29(5):782-94. doi: 10.1016/j.immuni.2008.09.016.

38.

B lymphocyte activation by coinfection prevents immune control of friend virus infection.

Marques R, Antunes I, Eksmond U, Stoye J, Hasenkrug K, Kassiotis G.

J Immunol. 2008 Sep 1;181(5):3432-40.

39.

Immunology. Immunity benefits from a little suppression.

Kassiotis G, O'Garra A.

Science. 2008 May 30;320(5880):1168-9. doi: 10.1126/science.1159090. No abstract available.

PMID:
18511677
40.
41.

CD4+ memory T cells: functional differentiation and homeostasis.

Stockinger B, Bourgeois C, Kassiotis G.

Immunol Rev. 2006 Jun;211:39-48. Review.

PMID:
16824115
42.

Functional specialization of memory Th cells revealed by expression of integrin CD49b.

Kassiotis G, Gray D, Kiafard Z, Zwirner J, Stockinger B.

J Immunol. 2006 Jul 15;177(2):968-75.

43.

Onset and progression in inherited ALS determined by motor neurons and microglia.

Boillée S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G, Cleveland DW.

Science. 2006 Jun 2;312(5778):1389-92.

44.

Apoptosis of oligodendrocytes via Fas and TNF-R1 is a key event in the induction of experimental autoimmune encephalomyelitis.

Hövelmeyer N, Hao Z, Kranidioti K, Kassiotis G, Buch T, Frommer F, von Hoch L, Kramer D, Minichiello L, Kollias G, Lassmann H, Waisman A.

J Immunol. 2005 Nov 1;175(9):5875-84.

45.

A major role for memory CD4 T cells in the control of lymphopenia-induced proliferation of naive CD4 T cells.

Bourgeois C, Kassiotis G, Stockinger B.

J Immunol. 2005 May 1;174(9):5316-23.

46.
47.

CD4 T-cell memory.

Stockinger B, Kassiotis G, Bourgeois C.

Semin Immunol. 2004 Oct;16(5):295-303. Review.

PMID:
15528074
48.

Homeostasis and T cell regulation.

Stockinger B, Kassiotis G, Bourgeois C.

Curr Opin Immunol. 2004 Dec;16(6):775-9. Review.

PMID:
15511672
49.

The concept of space and competition in immune regulation.

Stockinger B, Barthlott T, Kassiotis G.

Immunology. 2004 Mar;111(3):241-7. Review. No abstract available.

50.

Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells.

Kassiotis G, Zamoyska R, Stockinger B.

J Exp Med. 2003 Apr 21;197(8):1007-16.

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