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Items: 22

1.

Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and Cancer.

Chen CC, Feng W, Lim PX, Kass EM, Jasin M.

Annu Rev Cancer Biol. 2018 Mar;2:313-336. doi: 10.1146/annurev-cancerbio-030617-050502. Epub 2017 Dec 1.

2.

ATM loss leads to synthetic lethality in BRCA1 BRCT mutant mice associated with exacerbated defects in homology-directed repair.

Chen CC, Kass EM, Yen WF, Ludwig T, Moynahan ME, Chaudhuri J, Jasin M.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7665-7670. doi: 10.1073/pnas.1706392114. Epub 2017 Jun 28.

3.

Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma.

Kondrashova O, Nguyen M, Shield-Artin K, Tinker AV, Teng NNH, Harrell MI, Kuiper MJ, Ho GY, Barker H, Jasin M, Prakash R, Kass EM, Sullivan MR, Brunette GJ, Bernstein KA, Coleman RL, Floquet A, Friedlander M, Kichenadasse G, O'Malley DM, Oza A, Sun J, Robillard L, Maloney L, Bowtell D, Giordano H, Wakefield MJ, Kaufmann SH, Simmons AD, Harding TC, Raponi M, McNeish IA, Swisher EM, Lin KK, Scott CL; AOCS Study Group.

Cancer Discov. 2017 Sep;7(9):984-998. doi: 10.1158/2159-8290.CD-17-0419. Epub 2017 Jun 6.

4.

Robust homology-directed repair within mouse mammary tissue is not specifically affected by Brca2 mutation.

Kass EM, Lim PX, Helgadottir HR, Moynahan ME, Jasin M.

Nat Commun. 2016 Oct 25;7:13241. doi: 10.1038/ncomms13241.

5.

SECURITY STARTS AT ENCRYPTION. Organizations step up data defense efforts.

Kass EM.

Health Data Manag. 2016 Mar-Apr;24(3):24-6. No abstract available.

PMID:
27280191
6.

When Genome Maintenance Goes Badly Awry.

Kass EM, Moynahan ME, Jasin M.

Mol Cell. 2016 Jun 2;62(5):777-87. doi: 10.1016/j.molcel.2016.05.021. Review.

7.

SWITCHING EHRs? HOW TO AVOID TAKING A HIT.

Kass EM.

Health Data Manag. 2015 Sep-Oct;23(8):24, 26. No abstract available.

PMID:
26594718
8.

PROVIDERS TURN TO ANALYTICS.

Kass EM.

Health Data Manag. 2015 Jul-Aug;23(7):22, 24-6. No abstract available.

PMID:
26389149
9.

ROUND TABLE: HOW TO PROTECT PATIENT DATA. A panel of hospital security experts sheds light on the biggest threats to patient privacy and what they're doing to safeguard medical records.

Kass EM, Skvarenina M, Syed H, Mertz J, Houston J, Dunn G, Rhodes R, Hughes K.

Health Data Manag. 2015 Apr;23(4):30, 33-4, 36 passim. No abstract available.

PMID:
26199974
11.

Performance-based medicine drives data governance. Analytics spur efforts to ensure purity, consistency of data.

Kass EM.

Health Data Manag. 2015 Jun;23(6):23-4, 26. No abstract available.

PMID:
26182538
12.

Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis.

Dowdle JA, Mehta M, Kass EM, Vuong BQ, Inagaki A, Egli D, Jasin M, Keeney S.

PLoS Genet. 2013 Nov;9(11):e1003945. doi: 10.1371/journal.pgen.1003945. Epub 2013 Nov 7.

13.

Androgen receptor signaling regulates DNA repair in prostate cancers.

Polkinghorn WR, Parker JS, Lee MX, Kass EM, Spratt DE, Iaquinta PJ, Arora VK, Yen WF, Cai L, Zheng D, Carver BS, Chen Y, Watson PA, Shah NP, Fujisawa S, Goglia AG, Gopalan A, Hieronymus H, Wongvipat J, Scardino PT, Zelefsky MJ, Jasin M, Chaudhuri J, Powell SN, Sawyers CL.

Cancer Discov. 2013 Nov;3(11):1245-53. doi: 10.1158/2159-8290.CD-13-0172. Epub 2013 Sep 11.

14.

Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase.

Kass EM, Helgadottir HR, Chen CC, Barbera M, Wang R, Westermark UK, Ludwig T, Moynahan ME, Jasin M.

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5564-9. doi: 10.1073/pnas.1216824110. Epub 2013 Mar 18.

15.

APC/C(Cdc20) targets E2F1 for degradation in prometaphase.

Peart MJ, Poyurovsky MV, Kass EM, Urist M, Verschuren EW, Summers MK, Jackson PK, Prives C.

Cell Cycle. 2010 Oct 1;9(19):3956-64. Epub 2010 Oct 26.

16.

Collaboration and competition between DNA double-strand break repair pathways.

Kass EM, Jasin M.

FEBS Lett. 2010 Sep 10;584(17):3703-8. doi: 10.1016/j.febslet.2010.07.057. Epub 2010 Aug 5. Review.

17.

Loss of 53BP1 is a gain for BRCA1 mutant cells.

Kass EM, Moynahan ME, Jasin M.

Cancer Cell. 2010 May 18;17(5):423-5. doi: 10.1016/j.ccr.2010.04.021.

18.

Mdm2 and PCAF increase Chk2 ubiquitination and degradation independently of their intrinsic E3 ligase activities.

Kass EM, Poyurovsky MV, Zhu Y, Prives C.

Cell Cycle. 2009 Feb 1;8(3):430-7. Epub 2009 Feb 12.

PMID:
19176998
19.

Stability of checkpoint kinase 2 is regulated via phosphorylation at serine 456.

Kass EM, Ahn J, Tanaka T, Freed-Pastor WA, Keezer S, Prives C.

J Biol Chem. 2007 Oct 12;282(41):30311-21. Epub 2007 Aug 21.

20.

BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.

Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM.

Cell. 2001 Apr 6;105(1):149-60.

21.

Metabolic and genetic determinants of HDL metabolism and hepatic lipase activity in normolipidemic females.

De Oliveira e Silva ER, Kong M, Han Z, Starr C, Kass EM, Juo SH, Foster D, Dansky HM, Merkel M, Cundey K, Brinton EA, Breslow JL, Smith JD.

J Lipid Res. 1999 Jul;40(7):1211-21.

22.

Rickettsialpox in a New York City hospital, 1980 to 1989.

Kass EM, Szaniawski WK, Levy H, Leach J, Srinivasan K, Rives C.

N Engl J Med. 1994 Dec 15;331(24):1612-7.

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