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Items: 1 to 50 of 414

1.

Large Particle Fluorescence-Activated Cell Sorting Enables High-Quality Single-Cell RNA Sequencing and Functional Analysis of Adult Cardiomyocytes.

Kannan S, Miyamoto M, Lin BL, Zhu R, Murphy S, Kass DA, Andersen P, Kwon C.

Circ Res. 2019 Aug 16;125(5):567-569. doi: 10.1161/CIRCRESAHA.119.315493. Epub 2019 Aug 15. No abstract available.

PMID:
31415233
2.

Osteopontin Promotes Left Ventricular Diastolic Dysfunction Through a Mitochondrial Pathway.

Yousefi K, Irion CI, Takeuchi LM, Ding W, Lambert G, Eisenberg T, Sukkar S, Granzier HL, Methawasin M, Lee DI, Hahn VS, Kass DA, Hatzistergos KE, Hare JM, Webster KA, Shehadeh LA.

J Am Coll Cardiol. 2019 Jun 4;73(21):2705-2718. doi: 10.1016/j.jacc.2019.02.074.

PMID:
31146816
3.

Leveraging Signaling Pathways to Treat Heart Failure With Reduced Ejection Fraction.

Pinilla-Vera M, Hahn VS, Kass DA.

Circ Res. 2019 May 24;124(11):1618-1632. doi: 10.1161/CIRCRESAHA.119.313682.

PMID:
31120818
4.

Response by Kass et al to Letter Regarding Article, "Chronic Atrial and Ventricular Pacing in the Mouse: Application to Model Cardiac Dyssynchrony and Resynchronization in Heart Failure".

Kass DA, Nakagawa R, Ståhlberg M.

Circ Heart Fail. 2019 May;12(5):e006094. doi: 10.1161/CIRCHEARTFAILURE.119.006094. No abstract available.

PMID:
31079489
5.

In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease.

Lin BL, Matera D, Doerner JF, Zheng N, Del Camino D, Mishra S, Bian H, Zeveleva S, Zhen X, Blair NT, Chong JA, Hessler DP, Bedja D, Zhu G, Muller GK, Ranek MJ, Pantages L, McFarland M, Netherton MR, Berry A, Wong D, Rast G, Qian HS, Weldon SM, Kuo JJ, Sauer A, Sarko C, Moran MM, Kass DA, Pullen SS.

Proc Natl Acad Sci U S A. 2019 May 14;116(20):10156-10161. doi: 10.1073/pnas.1815354116. Epub 2019 Apr 26.

PMID:
31028142
6.

Nitrosative stress drives heart failure with preserved ejection fraction.

Schiattarella GG, Altamirano F, Tong D, French KM, Villalobos E, Kim SY, Luo X, Jiang N, May HI, Wang ZV, Hill TM, Mammen PPA, Huang J, Lee DI, Hahn VS, Sharma K, Kass DA, Lavandero S, Gillette TG, Hill JA.

Nature. 2019 Apr;568(7752):351-356. doi: 10.1038/s41586-019-1100-z. Epub 2019 Apr 10.

7.

Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury.

Barefield DY, McNamara JW, Lynch TL, Kuster DWD, Govindan S, Haar L, Wang Y, Taylor EN, Lorenz JN, Nieman ML, Zhu G, Luther PK, Varró A, Dobrev D, Ai X, Janssen PML, Kass DA, Jones WK, Gilbert RJ, Sadayappan S.

J Mol Cell Cardiol. 2019 Apr;129:236-246. doi: 10.1016/j.yjmcc.2019.03.006. Epub 2019 Mar 9.

8.

Fresh evidence overturns the identification of a factor involved in blood-vessel dilation.

Kass DA.

Nature. 2019 Feb;566(7745):462-464. doi: 10.1038/d41586-019-00508-z. No abstract available.

PMID:
30809049
9.

Chronic Atrial and Ventricular Pacing in the Mouse.

Ståhlberg M, Nakagawa R, Bedja D, Zhu G, Lin BL, Saberi A, Lee DI, Kass DA.

Circ Heart Fail. 2019 Feb;12(2):e005655. doi: 10.1161/CIRCHEARTFAILURE.118.005655.

PMID:
30764638
10.

PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress.

Ranek MJ, Kokkonen-Simon KM, Chen A, Dunkerly-Eyring BL, Vera MP, Oeing CU, Patel CH, Nakamura T, Zhu G, Bedja D, Sasaki M, Holewinski RJ, Van Eyk JE, Powell JD, Lee DI, Kass DA.

Nature. 2019 Feb;566(7743):264-269. doi: 10.1038/s41586-019-0895-y. Epub 2019 Jan 30.

11.

Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis.

Zhang QJ, Tran TAT, Wang M, Ranek MJ, Kokkonen-Simon KM, Gao J, Luo X, Tan W, Kyrychenko V, Liao L, Xu J, Hill JA, Olson EN, Kass DA, Martinez ED, Liu ZP.

Nat Commun. 2018 Dec 7;9(1):5230. doi: 10.1038/s41467-018-07173-2.

12.

Randomized Evaluation of Heart Failure With Preserved Ejection Fraction Patients With Acute Heart Failure and Dopamine: The ROPA-DOP Trial.

Sharma K, Vaishnav J, Kalathiya R, Hu JR, Miller J, Shah N, Hill T, Sharp M, Tsao A, Alexander KM, Gupta R, Montemayor K, Kovell L, Chasler JE, Lee YJ, Fine DM, Kass DA, Weiss RG, Thiemann DR, Ndumele CE, Schulman SP, Russell SD; Osler Medical Housestaff.

JACC Heart Fail. 2018 Oct;6(10):859-870. doi: 10.1016/j.jchf.2018.04.008. Epub 2018 Aug 8.

13.

Marked disparity of microRNA modulation by cGMP-selective PDE5 versus PDE9 inhibitors in heart disease.

Kokkonen-Simon KM, Saberi A, Nakamura T, Ranek MJ, Zhu G, Bedja D, Kuhn M, Halushka MK, Lee DI, Kass DA.

JCI Insight. 2018 Aug 9;3(15). pii: 121739. doi: 10.1172/jci.insight.121739. eCollection 2018 Aug 9.

14.

Acute Enhancement of Cardiac Function by Phosphodiesterase Type 1 Inhibition.

Hashimoto T, Kim GE, Tunin RS, Adesiyun T, Hsu S, Nakagawa R, Zhu G, O'Brien JJ, Hendrick JP, Davis RE, Yao W, Beard D, Hoxie HR, Wennogle LP, Lee DI, Kass DA.

Circulation. 2018 Oct 30;138(18):1974-1987. doi: 10.1161/CIRCULATIONAHA.117.030490.

PMID:
30030415
15.

Pulmonary Effective Arterial Elastance as a Measure of Right Ventricular Afterload and Its Prognostic Value in Pulmonary Hypertension Due to Left Heart Disease.

Tampakakis E, Shah SJ, Borlaug BA, Leary PJ, Patel HH, Miller WL, Kelemen BW, Houston BA, Kolb TM, Damico R, Mathai SC, Kasper EK, Hassoun PM, Kass DA, Tedford RJ.

Circ Heart Fail. 2018 Apr;11(4):e004436. doi: 10.1161/CIRCHEARTFAILURE.117.004436.

16.

Protein S-Nitrosylation Controls Glycogen Synthase Kinase 3β Function Independent of Its Phosphorylation State.

Wang SB, Venkatraman V, Crowgey EL, Liu T, Fu Z, Holewinski R, Ranek M, Kass DA, O'Rourke B, Van Eyk JE.

Circ Res. 2018 May 25;122(11):1517-1531. doi: 10.1161/CIRCRESAHA.118.312789. Epub 2018 Mar 21.

17.

Prevention of PKG-1α Oxidation Suppresses Antihypertrophic/Antifibrotic Effects From PDE5 Inhibition but not sGC Stimulation.

Nakamura T, Zhu G, Ranek MJ, Kokkonen-Simon K, Zhang M, Kim GE, Tsujita K, Kass DA.

Circ Heart Fail. 2018 Mar;11(3):e004740. doi: 10.1161/CIRCHEARTFAILURE.117.004740.

18.

Right Ventricular Myofilament Functional Differences in Humans With Systemic Sclerosis-Associated Versus Idiopathic Pulmonary Arterial Hypertension.

Hsu S, Kokkonen-Simon KM, Kirk JA, Kolb TM, Damico RL, Mathai SC, Mukherjee M, Shah AA, Wigley FM, Margulies KB, Hassoun PM, Halushka MK, Tedford RJ, Kass DA.

Circulation. 2018 May 29;137(22):2360-2370. doi: 10.1161/CIRCULATIONAHA.117.033147. Epub 2018 Jan 19.

19.

Transient receptor potential channel 6 regulates abnormal cardiac S-nitrosylation in Duchenne muscular dystrophy.

Chung HS, Kim GE, Holewinski RJ, Venkatraman V, Zhu G, Bedja D, Kass DA, Van Eyk JE.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10763-E10771. doi: 10.1073/pnas.1712623114. Epub 2017 Nov 29.

20.

Heart Failure-Related Hyperphosphorylation in the Cardiac Troponin I C Terminus Has Divergent Effects on Cardiac Function In Vivo.

Li Y, Zhu G, Paolocci N, Zhang P, Takahashi C, Okumus N, Heravi A, Keceli G, Ramirez-Correa G, Kass DA, Murphy AM.

Circ Heart Fail. 2017 Sep;10(9). pii: e003850. doi: 10.1161/CIRCHEARTFAILURE.117.003850.

21.

Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice.

Rouf R, MacFarlane EG, Takimoto E, Chaudhary R, Nagpal V, Rainer PP, Bindman JG, Gerber EE, Bedja D, Schiefer C, Miller KL, Zhu G, Myers L, Amat-Alarcon N, Lee DI, Koitabashi N, Judge DP, Kass DA, Dietz HC.

JCI Insight. 2017 Aug 3;2(15). pii: 91588. doi: 10.1172/jci.insight.91588. eCollection 2017 Aug 3.

22.

Why publish in the American Journal of Physiology-Heart and Circulatory Physiology?

Zucker IH, Lindsey ML, Delmar M, De Windt LJ, Des Rosiers C, Diz DI, Hester RL, Jones SP, Kanagy NL, Kitakaze M, Liao R, Lopaschuk GD, Patel KP, Recchia FA, Sadoshima J, Shah AM, Ungvari Z, Benjamin IJ, Blaustein MP, Charkoudian N, Efimov IR, Gutterman D, Kass DA, Liao Y, O'Leary DS, Ripplinger CM, Wolin MS.

Am J Physiol Heart Circ Physiol. 2017 Aug 1;313(2):H221-H223. doi: 10.1152/ajpheart.00329.2017. Epub 2017 Jun 16. No abstract available.

23.

Inorganic Nitrates: Qi for Heart Failure With Preserved Ejection Fraction?

Sharma K, Kass DA.

Circ Res. 2017 Mar 31;120(7):1057-1059. doi: 10.1161/CIRCRESAHA.117.310699. No abstract available.

24.

Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy.

Cho GS, Lee DI, Tampakakis E, Murphy S, Andersen P, Uosaki H, Chelko S, Chakir K, Hong I, Seo K, Chen HV, Chen X, Basso C, Houser SR, Tomaselli GF, O'Rourke B, Judge DP, Kass DA, Kwon C.

Cell Rep. 2017 Jan 10;18(2):571-582. doi: 10.1016/j.celrep.2016.12.040.

25.

Cellular and Molecular Aspects of Dyssynchrony and Resynchronization.

Kirk JA, Kass DA.

Heart Fail Clin. 2017 Jan;13(1):29-41. doi: 10.1016/j.hfc.2016.07.003. Review.

PMID:
27886930
26.

Heart Rate Dependence of the Pulmonary Resistance x Compliance (RC) Time and Impact on Right Ventricular Load.

Metkus TS, Mullin CJ, Grandin EW, Rame JE, Tampakakis E, Hsu S, Kolb TM, Damico R, Hassoun PM, Kass DA, Mathai SC, Tedford RJ.

PLoS One. 2016 Nov 18;11(11):e0166463. doi: 10.1371/journal.pone.0166463. eCollection 2016.

27.

Cardiac Phosphodiesterases and Their Modulation for Treating Heart Disease.

Kim GE, Kass DA.

Handb Exp Pharmacol. 2017;243:249-269. doi: 10.1007/164_2016_82. Review.

28.

Nanodomain Regulation of Cardiac Cyclic Nucleotide Signaling by Phosphodiesterases.

Kokkonen K, Kass DA.

Annu Rev Pharmacol Toxicol. 2017 Jan 6;57:455-479. doi: 10.1146/annurev-pharmtox-010716-104756. Epub 2016 Oct 12. Review.

PMID:
27732797
29.

A Simple Adaptive Transfer Function for Deriving the Central Blood Pressure Waveform from a Radial Blood Pressure Waveform.

Gao M, Rose WC, Fetics B, Kass DA, Chen CH, Mukkamala R.

Sci Rep. 2016 Sep 14;6:33230. doi: 10.1038/srep33230.

30.

Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction: A Multiorgan Roadmap.

Shah SJ, Kitzman DW, Borlaug BA, van Heerebeek L, Zile MR, Kass DA, Paulus WJ.

Circulation. 2016 Jul 5;134(1):73-90. doi: 10.1161/CIRCULATIONAHA.116.021884. Review.

31.

Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction.

Ngkelo A, Richart A, Kirk JA, Bonnin P, Vilar J, Lemitre M, Marck P, Branchereau M, Le Gall S, Renault N, Guerin C, Ranek MJ, Kervadec A, Danelli L, Gautier G, Blank U, Launay P, Camerer E, Bruneval P, Menasche P, Heymes C, Luche E, Casteilla L, Cousin B, Rodewald HR, Kass DA, Silvestre JS.

J Exp Med. 2016 Jun 27;213(7):1353-74. doi: 10.1084/jem.20160081.

32.

Novel, single-beat approach for determining both end-systolic pressure-dimension relationship and preload recruitable stroke work.

Inuzuka R, Kass DA, Senzaki H.

Open Heart. 2016 Jun 15;3(1):e000451. doi: 10.1136/openhrt-2016-000451. eCollection 2016.

33.

Old dog, new tricks: novel cardiac targets and stress regulation by protein kinase G.

Rainer PP, Kass DA.

Cardiovasc Res. 2016 Jul 15;111(2):154-62. doi: 10.1093/cvr/cvw107. Epub 2016 Jun 13. Review.

34.

Right Ventricular Functional Reserve in Pulmonary Arterial Hypertension.

Hsu S, Houston BA, Tampakakis E, Bacher AC, Rhodes PS, Mathai SC, Damico RL, Kolb TM, Hummers LK, Shah AA, McMahan Z, Corona-Villalobos CP, Zimmerman SL, Wigley FM, Hassoun PM, Kass DA, Tedford RJ.

Circulation. 2016 Jun 14;133(24):2413-22. doi: 10.1161/CIRCULATIONAHA.116.022082. Epub 2016 May 11.

35.

Tetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling.

Hashimoto T, Sivakumaran V, Carnicer R, Zhu G, Hahn VS, Bedja D, Recalde A, Duglan D, Channon KM, Casadei B, Kass DA.

J Am Heart Assoc. 2016 Mar 21;5(3):e003208. doi: 10.1161/JAHA.116.003208.

36.

Association Between Left Atrial Stiffness Index and Atrial Fibrillation Recurrence in Patients Undergoing Left Atrial Ablation.

Khurram IM, Maqbool F, Berger RD, Marine JE, Spragg DD, Ashikaga H, Zipunnikov V, Kass DA, Calkins H, Nazarian S, Zimmerman SL.

Circ Arrhythm Electrophysiol. 2016 Mar;9(3). pii: e003163. doi: 10.1161/CIRCEP.115.003163.

PMID:
26966287
37.

Profilin modulates sarcomeric organization and mediates cardiomyocyte hypertrophy.

Kooij V, Viswanathan MC, Lee DI, Rainer PP, Schmidt W, Kronert WA, Harding SE, Kass DA, Bernstein SI, Van Eyk JE, Cammarato A.

Cardiovasc Res. 2016 May 15;110(2):238-48. doi: 10.1093/cvr/cvw050. Epub 2016 Mar 7.

38.

Can Nitrite AMPk Up Sirt-ainty to Treat Heart Failure With Preserved Ejection Fraction?

Hsu S, Kass DA.

Circulation. 2016 Feb 23;133(8):692-4. doi: 10.1161/CIRCULATIONAHA.116.021409. Epub 2016 Jan 26. No abstract available.

39.

Standard Operating Procedures (SOPs) for Evaluating the Heart in Preclinical Studies of Duchenne Muscular Dystrophy.

Duan D, Rafael-Fortney JA, Blain A, Kass DA, McNally EM, Metzger JM, Spurney CF, Kinnett K.

J Cardiovasc Transl Res. 2016 Feb;9(1):85-6. doi: 10.1007/s12265-015-9669-6. Epub 2015 Dec 30.

40.

Pacemaker-induced transient asynchrony suppresses heart failure progression.

Kirk JA, Chakir K, Lee KH, Karst E, Holewinski RJ, Pironti G, Tunin RS, Pozios I, Abraham TP, de Tombe P, Rockman HA, Van Eyk JE, Craig R, Farazi TG, Kass DA.

Sci Transl Med. 2015 Dec 23;7(319):319ra207. doi: 10.1126/scitranslmed.aad2899.

41.

Cellular and Molecular Aspects of Dyssynchrony and Resynchronization.

Kirk JA, Kass DA.

Card Electrophysiol Clin. 2015 Dec;7(4):585-97. doi: 10.1016/j.ccep.2015.08.011. Review.

42.

Transcriptional Landscape of Cardiomyocyte Maturation.

Uosaki H, Cahan P, Lee DI, Wang S, Miyamoto M, Fernandez L, Kass DA, Kwon C.

Cell Rep. 2015 Nov 24;13(8):1705-16. doi: 10.1016/j.celrep.2015.10.032. Epub 2015 Nov 12.

43.
44.

Molecular Screen Identifies Cardiac Myosin-Binding Protein-C as a Protein Kinase G-Iα Substrate.

Thoonen R, Giovanni S, Govindan S, Lee DI, Wang GR, Calamaras TD, Takimoto E, Kass DA, Sadayappan S, Blanton RM.

Circ Heart Fail. 2015 Nov;8(6):1115-22. doi: 10.1161/CIRCHEARTFAILURE.115.002308. Epub 2015 Oct 18.

45.

Outcomes and worsening renal function in patients hospitalized with heart failure with preserved ejection fraction.

Sharma K, Hill T, Grams M, Daya NR, Hays AG, Fine D, Thiemann DR, Weiss RG, Tedford RJ, Kass DA, Schulman SP, Russell SD.

Am J Cardiol. 2015 Nov 15;116(10):1534-40. doi: 10.1016/j.amjcard.2015.08.019. Epub 2015 Aug 31.

PMID:
26410603
46.

Dual Labeling Biotin Switch Assay to Reduce Bias Derived From Different Cysteine Subpopulations: A Method to Maximize S-Nitrosylation Detection.

Chung HS, Murray CI, Venkatraman V, Crowgey EL, Rainer PP, Cole RN, Bomgarden RD, Rogers JC, Balkan W, Hare JM, Kass DA, Van Eyk JE.

Circ Res. 2015 Oct 23;117(10):846-57. doi: 10.1161/CIRCRESAHA.115.307336. Epub 2015 Sep 3.

47.

Citrullination of myofilament proteins in heart failure.

Fert-Bober J, Giles JT, Holewinski RJ, Kirk JA, Uhrigshardt H, Crowgey EL, Andrade F, Bingham CO 3rd, Park JK, Halushka MK, Kass DA, Bathon JM, Van Eyk JE.

Cardiovasc Res. 2015 Nov 1;108(2):232-42. doi: 10.1093/cvr/cvv185. Epub 2015 Jun 25.

48.

Right ventricular remodeling in idiopathic and scleroderma-associated pulmonary arterial hypertension: two distinct phenotypes.

Kelemen BW, Mathai SC, Tedford RJ, Damico RL, Corona-Villalobos C, Kolb TM, Chaisson NF, Harris TH, Zimmerman SL, Kamel IR, Kass DA, Hassoun PM.

Pulm Circ. 2015 Jun;5(2):327-34. doi: 10.1086/680356.

49.

Stressed hearts inflame the body (in a good way).

Hashimoto T, Kass DA.

Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7113-4. doi: 10.1073/pnas.1507821112. Epub 2015 May 21. No abstract available.

50.

Prevention of PKG1α oxidation augments cardioprotection in the stressed heart.

Nakamura T, Ranek MJ, Lee DI, Shalkey Hahn V, Kim C, Eaton P, Kass DA.

J Clin Invest. 2015 Jun;125(6):2468-72. doi: 10.1172/JCI80275. Epub 2015 May 4.

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