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Items: 37

1.

TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis.

Wong EB, Gold MC, Meermeier EW, Xulu BZ, Khuzwayo S, Sullivan ZA, Mahyari E, Rogers Z, Kløverpris H, Sharma PK, Worley AH, Lalloo U, Baijnath P, Ambaram A, Naidoo L, Suleman M, Madansein R, McLaren JE, Ladell K, Miners KL, Price DA, Behar SM, Nielsen M, Kasprowicz VO, Leslie A, Bishai WR, Ndung'u T, Lewinsohn DM.

Commun Biol. 2019 Jun 5;2:203. doi: 10.1038/s42003-019-0442-2. eCollection 2019.

2.

Evaluation of a synthetic peptide for the detection of anti-Mycobacterium tuberculosis curli pili IgG antibodies in patients with pulmonary tuberculosis.

Naidoo N, Pillay B, Bubb M, Pym A, Chiliza T, Naidoo K, Ndung'u T, Kasprowicz VO, Pillay M.

Tuberculosis (Edinb). 2018 Mar;109:80-84. doi: 10.1016/j.tube.2018.01.007. Epub 2018 Feb 3.

3.

The role of mucosal-associated invariant T cells in infectious diseases.

Wong EB, Ndung'u T, Kasprowicz VO.

Immunology. 2017 Jan;150(1):45-54. doi: 10.1111/imm.12673. Epub 2016 Oct 26. Review.

4.

Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression.

Kløverpris HN, Kazer SW, Mjösberg J, Mabuka JM, Wellmann A, Ndhlovu Z, Yadon MC, Nhamoyebonde S, Muenchhoff M, Simoni Y, Andersson F, Kuhn W, Garrett N, Burgers WA, Kamya P, Pretorius K, Dong K, Moodley A, Newell EW, Kasprowicz V, Abdool Karim SS, Goulder P, Shalek AK, Walker BD, Ndung'u T, Leslie A.

Immunity. 2016 Feb 16;44(2):391-405. doi: 10.1016/j.immuni.2016.01.006. Epub 2016 Feb 2.

5.

Host Protein Biomarkers Identify Active Tuberculosis in HIV Uninfected and Co-infected Individuals.

Achkar JM, Cortes L, Croteau P, Yanofsky C, Mentinova M, Rajotte I, Schirm M, Zhou Y, Junqueira-Kipnis AP, Kasprowicz VO, Larsen M, Allard R, Hunter J, Paramithiotis E.

EBioMedicine. 2015 Jul 30;2(9):1160-8. doi: 10.1016/j.ebiom.2015.07.039. eCollection 2015 Sep.

6.

HIV Disrupts Human T Cells That Target Mycobacterial Glycolipids.

Kasprowicz VO, Cheng TY, Ndung'u T, Sunpath H, Moody DB, Kasmar AG.

J Infect Dis. 2016 Feb 15;213(4):628-33. doi: 10.1093/infdis/jiv455. Epub 2015 Sep 15.

7.

Latent and Active Tuberculosis Infection Increase Immune Activation in Individuals Co-Infected with HIV.

Sullivan ZA, Wong EB, Ndung'u T, Kasprowicz VO, Bishai WR.

EBioMedicine. 2015 Apr 1;2(4):334-340.

8.

Co-infection with Mycobacterium tuberculosis impairs HIV-Specific CD8+ and CD4+ T cell functionality.

Chetty S, Govender P, Zupkosky J, Pillay M, Ghebremichael M, Moosa MY, Ndung'u T, Porichis F, Kasprowicz VO.

PLoS One. 2015 Mar 17;10(3):e0118654. doi: 10.1371/journal.pone.0118654. eCollection 2015. Erratum in: PLoS One. 2015 May 20;10 (5):e0127763.

9.

High expression of CD26 accurately identifies human bacteria-reactive MR1-restricted MAIT cells.

Sharma PK, Wong EB, Napier RJ, Bishai WR, Ndung'u T, Kasprowicz VO, Lewinsohn DA, Lewinsohn DM, Gold MC.

Immunology. 2015 Jul;145(3):443-53. doi: 10.1111/imm.12461. Epub 2015 Mar 29.

10.

Tuberculosis distorts the inhibitory impact of interleukin-10 in HIV infection.

Chetty S, Porichis F, Govender P, Zupkosky J, Ghebremichael M, Pillay M, Walker BD, Ndung'u T, Kaufmann DE, Kasprowicz VO.

AIDS. 2014 Nov 28;28(18):2671-6. doi: 10.1097/QAD.0000000000000437.

11.

Antibodies against Mycobacterial proteins as biomarkers for HIV-associated smear-negative tuberculosis.

Siev M, Wilson D, Kainth S, Kasprowicz VO, Feintuch CM, Jenny-Avital ER, Achkar JM.

Clin Vaccine Immunol. 2014 Jun;21(6):791-8. doi: 10.1128/CVI.00805-13. Epub 2014 Mar 26.

12.

TRIM5α and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment.

Singh R, Patel V, Mureithi MW, Naranbhai V, Ramsuran D, Tulsi S, Hiramen K, Werner L, Mlisana K, Altfeld M, Luban J, Kasprowicz V, Dheda K, Abdool Karim SS, Ndung'u T.

J Virol. 2014 Apr;88(8):4291-303. doi: 10.1128/JVI.03603-13. Epub 2014 Jan 29.

13.

Low levels of peripheral CD161++CD8+ mucosal associated invariant T (MAIT) cells are found in HIV and HIV/TB co-infection.

Wong EB, Akilimali NA, Govender P, Sullivan ZA, Cosgrove C, Pillay M, Lewinsohn DM, Bishai WR, Walker BD, Ndung'u T, Klenerman P, Kasprowicz VO.

PLoS One. 2013 Dec 31;8(12):e83474. doi: 10.1371/journal.pone.0083474. eCollection 2013. Erratum in: PLoS One. 2014;9(4):e95115.

14.

S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis.

Gopal R, Monin L, Torres D, Slight S, Mehra S, McKenna KC, Fallert Junecko BA, Reinhart TA, Kolls J, Báez-Saldaña R, Cruz-Lagunas A, Rodríguez-Reyna TS, Kumar NP, Tessier P, Roth J, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Cumming B, Kasprowicz VO, Steyn AJ, Babu S, Kaushal D, Zúñiga J, Vogl T, Rangel-Moreno J, Khader SA.

Am J Respir Crit Care Med. 2013 Nov 1;188(9):1137-46. doi: 10.1164/rccm.201304-0803OC.

15.

Procollagen III N-terminal propeptide and desmosine are released by matrix destruction in pulmonary tuberculosis.

Seddon J, Kasprowicz V, Walker NF, Yuen HM, Sunpath H, Tezera L, Meintjes G, Wilkinson RJ, Bishai WR, Friedland JS, Elkington PT.

J Infect Dis. 2013 Nov 15;208(10):1571-9. doi: 10.1093/infdis/jit343. Epub 2013 Aug 6.

16.

Prospective monitoring reveals dynamic levels of T cell immunity to Mycobacterium tuberculosis in HIV infected individuals.

Mitchell JE, Chetty S, Govender P, Pillay M, Jaggernath M, Kasmar A, Ndung'u T, Klenerman P, Walker BD, Kasprowicz VO.

PLoS One. 2012;7(6):e37920. doi: 10.1371/journal.pone.0037920. Epub 2012 Jun 7.

17.

MIGRAs: are they the new IGRAs? Development of monokine-amplified IFN-γ release assays.

Kasprowicz VO, Halliday JS, Mitchell J, Klenerman P.

Biomark Med. 2012 Apr;6(2):177-86. doi: 10.2217/BMM.12.13.

PMID:
22448791
18.

Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence.

Schulze Zur Wiesch J, Ciuffreda D, Lewis-Ximenez L, Kasprowicz V, Nolan BE, Streeck H, Aneja J, Reyor LL, Allen TM, Lohse AW, McGovern B, Chung RT, Kwok WW, Kim AY, Lauer GM.

J Exp Med. 2012 Jan 16;209(1):61-75. doi: 10.1084/jem.20100388. Epub 2012 Jan 2.

19.

Diagnosing latent tuberculosis in high-risk individuals: rising to the challenge in high-burden areas.

Kasprowicz VO, Churchyard G, Lawn SD, Squire SB, Lalvani A.

J Infect Dis. 2011 Nov 15;204 Suppl 4:S1168-78. doi: 10.1093/infdis/jir449. Review.

20.

Adjunctive tests for diagnosis of tuberculosis: serology, ELISPOT for site-specific lymphocytes, urinary lipoarabinomannan, string test, and fine needle aspiration.

Achkar JM, Lawn SD, Moosa MY, Wright CA, Kasprowicz VO.

J Infect Dis. 2011 Nov 15;204 Suppl 4:S1130-41. doi: 10.1093/infdis/jir450. Review.

21.

The tuberculosis and HIV epidemic in South Africa and the KwaZulu-Natal Research Institute for Tuberculosis and HIV.

Kasprowicz VO, Achkar JM, Wilson D.

J Infect Dis. 2011 Nov 15;204 Suppl 4:S1099-101. doi: 10.1093/infdis/jir414. No abstract available.

PMID:
21996691
22.

Comparative utility of cytokine levels and quantitative RD-1-specific T cell responses for rapid immunodiagnosis of tuberculous meningitis.

Patel VB, Singh R, Connolly C, Kasprowicz V, Ndung'u T, Dheda K.

J Clin Microbiol. 2011 Nov;49(11):3971-6. doi: 10.1128/JCM.01128-11. Epub 2011 Aug 31.

23.

A molecular assay for sensitive detection of pathogen-specific T-cells.

Kasprowicz VO, Mitchell JE, Chetty S, Govender P, Huang KH, Fletcher HA, Webster DP, Brown S, Kasmar A, Millington K, Day CL, Mkhwanazi N, McClurg C, Chonco F, Lalvani A, Walker BD, Ndung'u T, Klenerman P.

PLoS One. 2011;6(8):e20606. doi: 10.1371/journal.pone.0020606. Epub 2011 Aug 11.

24.

Comparison of a clinical prediction rule and a LAM antigen-detection assay for the rapid diagnosis of TBM in a high HIV prevalence setting.

Patel VB, Singh R, Connolly C, Kasprowicz V, Zumla A, Ndungu T, Dheda K.

PLoS One. 2010 Dec 22;5(12):e15664. doi: 10.1371/journal.pone.0015664.

25.

Cerebrospinal T-cell responses aid in the diagnosis of tuberculous meningitis in a human immunodeficiency virus- and tuberculosis-endemic population.

Patel VB, Singh R, Connolly C, Coovadia Y, Peer AK, Parag P, Kasprowicz V, Zumla A, Ndung'u T, Dheda K.

Am J Respir Crit Care Med. 2010 Aug 15;182(4):569-77. doi: 10.1164/rccm.200912-1931OC. Epub 2010 May 4.

26.

Hepatitis C virus (HCV) sequence variation induces an HCV-specific T-cell phenotype analogous to spontaneous resolution.

Kasprowicz V, Kang YH, Lucas M, Schulze zur Wiesch J, Kuntzen T, Fleming V, Nolan BE, Longworth S, Berical A, Bengsch B, Thimme R, Lewis-Ximenez L, Allen TM, Kim AY, Klenerman P, Lauer GM.

J Virol. 2010 Feb;84(3):1656-63. doi: 10.1128/JVI.01499-09. Epub 2009 Nov 11. Erratum in: J Virol. 2011 May;85(9):4636.

27.

Defining the directionality and quality of influenza virus-specific CD8+ T cell cross-reactivity in individuals infected with hepatitis C virus.

Kasprowicz V, Ward SM, Turner A, Grammatikos A, Nolan BE, Lewis-Ximenez L, Sharp C, Woodruff J, Fleming VM, Sims S, Walker BD, Sewell AK, Lauer GM, Klenerman P.

J Clin Invest. 2008 Mar;118(3):1143-53. doi: 10.1172/JCI33082. Erratum in: J Clin Invest. 2011 Mar 1;121(3):1223.

28.

CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation.

Northfield JW, Kasprowicz V, Lucas M, Kersting N, Bengsch B, Kim A, Phillips RE, Walker BD, Thimme R, Lauer G, Klenerman P.

Hepatology. 2008 Feb;47(2):396-406. doi: 10.1002/hep.22040. Erratum in: Hepatology. 2008 Mar;47(3):1102. Bengsh, Bertram [corrected to Bengsch, Bertram].

PMID:
18219672
29.

High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome.

Kasprowicz V, Schulze Zur Wiesch J, Kuntzen T, Nolan BE, Longworth S, Berical A, Blum J, McMahon C, Reyor LL, Elias N, Kwok WW, McGovern BG, Freeman G, Chung RT, Klenerman P, Lewis-Ximenez L, Walker BD, Allen TM, Kim AY, Lauer GM.

J Virol. 2008 Mar;82(6):3154-60. Epub 2007 Dec 26. Erratum in: J Virol. 2011 May;85(9):4633.

30.

Human keratinocyte induction of rapid effector function in antigen-specific memory CD4+ and CD8+ T cells.

Black AP, Ardern-Jones MR, Kasprowicz V, Bowness P, Jones L, Bailey AS, Ogg GS.

Eur J Immunol. 2007 Jun;37(6):1485-93.

31.

Immunologic evidence for lack of heterologous protection following resolution of HCV in patients with non-genotype 1 infection.

Schulze Zur Wiesch J, Lauer GM, Timm J, Kuntzen T, Neukamm M, Berical A, Jones AM, Nolan BE, Longworth SA, Kasprowicz V, McMahon C, Wurcel A, Lohse AW, Lewis-Ximenez LL, Chung RT, Kim AY, Allen TM, Walker BD.

Blood. 2007 Sep 1;110(5):1559-69. Epub 2007 May 2.

32.

Tracking of peptide-specific CD4+ T-cell responses after an acute resolving viral infection: a study of parvovirus B19.

Kasprowicz V, Isa A, Tolfvenstam T, Jeffery K, Bowness P, Klenerman P.

J Virol. 2006 Nov;80(22):11209-17. Epub 2006 Aug 30.

33.

A highly restricted T-cell receptor dominates the CD8+ T-cell response to parvovirus B19 infection in HLA-A*2402-positive individuals.

Kasprowicz V, Isa A, Jeffery K, Broliden K, Tolfvenstam T, Klenerman P, Bowness P.

J Virol. 2006 Jul;80(13):6697-701.

34.

Aberrant cellular immune responses in humans infected persistently with parvovirus B19.

Isa A, Norbeck O, Hirbod T, Lundqvist A, Kasprowicz V, Bowness P, Klenerman P, Broliden K, Tolfvenstam T.

J Med Virol. 2006 Jan;78(1):129-33.

PMID:
16299714
35.

Prolonged activation of virus-specific CD8+T cells after acute B19 infection.

Isa A, Kasprowicz V, Norbeck O, Loughry A, Jeffery K, Broliden K, Klenerman P, Tolfvenstam T, Bowness P.

PLoS Med. 2005 Dec;2(12):e343. Epub 2005 Nov 1.

36.

Sustained CD8+ T-cell responses induced after acute parvovirus B19 infection in humans.

Norbeck O, Isa A, Pöhlmann C, Broliden K, Kasprowicz V, Bowness P, Klenerman P, Tolfvenstam T.

J Virol. 2005 Sep;79(18):12117-21.

37.

Ultra-sensitive class I tetramer analysis reveals previously undetectable populations of antiviral CD8+ T cells.

Barnes E, Ward SM, Kasprowicz VO, Dusheiko G, Klenerman P, Lucas M.

Eur J Immunol. 2004 Jun;34(6):1570-7.

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