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Items: 1 to 50 of 128

1.

β-amyloid cytotoxicity is prevented by natural achillolide A.

Elmann A, Telerman A, Ofir R, Kashman Y, Lazarov O.

J Nat Med. 2018 Jun;72(3):626-631. doi: 10.1007/s11418-018-1191-0. Epub 2018 Mar 15.

2.

Molecular and ultrastructural studies of a fibrillar collagen from octocoral (Cnidaria).

Orgel JPRO, Sella I, Madhurapantula RS, Antipova O, Mandelberg Y, Kashman Y, Benayahu D, Benayahu Y.

J Exp Biol. 2017 Sep 15;220(Pt 18):3327-3335. doi: 10.1242/jeb.163824. Epub 2017 Jul 13.

3.

3,5,4'-trihydroxy-6,7,3'-trimethoxyflavone protects against beta amyloid-induced neurotoxicity through antioxidative activity and interference with cell signaling.

Telerman A, Ofir R, Kashman Y, Elmann A.

BMC Complement Altern Med. 2017 Jun 23;17(1):332. doi: 10.1186/s12906-017-1840-y.

4.

Mollecarbamates, Molleureas, and Molledihydroisoquinolone, o-Carboxyphenethylamide Metabolites of the Ascidian Didemnum molle Collected in Madagascar.

Issac M, Aknin M, Gauvin-Bialecki A, Pond CD, Barrows LR, Kashman Y, Carmeli S.

J Nat Prod. 2017 Jun 23;80(6):1844-1852. doi: 10.1021/acs.jnatprod.7b00123. Epub 2017 Jun 2.

PMID:
28574260
5.

Characterization of non-dialyzable constituents from cranberry juice that inhibit adhesion, co-aggregation and biofilm formation by oral bacteria.

Neto CC, Penndorf KA, Feldman M, Meron-Sudai S, Zakay-Rones Z, Steinberg D, Fridman M, Kashman Y, Ginsburg I, Ofek I, Weiss EI.

Food Funct. 2017 May 24;8(5):1955-1965. doi: 10.1039/c7fo00109f.

PMID:
28470309
6.
7.

Cyclotheonellazoles A-C, Potent Protease Inhibitors from the Marine Sponge Theonella aff. swinhoei.

Issac M, Aknin M, Gauvin-Bialecki A, De Voogd N, Ledoux A, Frederich M, Kashman Y, Carmeli S.

J Nat Prod. 2017 Apr 28;80(4):1110-1116. doi: 10.1021/acs.jnatprod.7b00028. Epub 2017 Feb 16.

PMID:
28207261
8.

Achillolide A Protects Astrocytes against Oxidative Stress by Reducing Intracellular Reactive Oxygen Species and Interfering with Cell Signaling.

Elmann A, Telerman A, Erlank H, Ofir R, Kashman Y, Beit-Yannai E.

Molecules. 2016 Mar 2;21(3):301. doi: 10.3390/molecules21030301.

9.

Bisdioxycalamenene: A Bis-Sesquiterpene from the Soft Coral Rhytisma fulvum fulvum.

Trifman YJ, Aknin M, Gauvin-Bialecki A, Benayahu Y, Carmeli S, Kashman Y.

Mar Drugs. 2016 Feb 19;14(2). pii: E41. doi: 10.3390/md14020041.

10.

Netamines O-S, Five New Tricyclic Guanidine Alkaloids from the Madagascar Sponge Biemna laboutei, and Their Antimalarial Activities.

Gros E, Martin MT, Sorres J, Moriou C, Vacelet J, Frederich M, Aknin M, Kashman Y, Gauvin-Bialecki A, Al-Mourabit A.

Chem Biodivers. 2015 Nov;12(11):1725-33. doi: 10.1002/cbdv.201400350.

PMID:
26567950
11.

Salarin C inhibits the maintenance of chronic myeloid leukemia progenitor cells.

Del Poggetto E, Tanturli M, Ben-Califa N, Gozzini A, Tusa I, Cheloni G, Marzi I, Cipolleschi MG, Kashman Y, Neumann D, Rovida E, Dello Sbarba P.

Cell Cycle. 2015;14(19):3146-54. doi: 10.1080/15384101.2015.1078029.

12.

Downregulation of microglial activation by achillolide A.

Elmann A, Telerman A, Mordechay S, Erlank H, Rindner M, Kashman Y, Ofir R.

Planta Med. 2015 Feb;81(3):215-21. doi: 10.1055/s-0034-1396204. Epub 2015 Feb 5.

PMID:
25654405
13.

3,5,4'-Trihydroxy-6,7,3'-trimethoxyflavone protects astrocytes against oxidative stress via interference with cell signaling and by reducing the levels of intracellular reactive oxygen species.

Elmann A, Telerman A, Mordechay S, Erlank H, Rindner M, Ofir R, Kashman Y.

Neurochem Int. 2014 Dec;78:67-75. doi: 10.1016/j.neuint.2014.09.003. Epub 2014 Sep 10.

PMID:
25217804
14.

Netamines H-N, tricyclic alkaloids from the marine sponge Biemna laboutei and their antimalarial activity.

Gros E, Al-Mourabit A, Martin MT, Sorres J, Vacelet J, Frederich M, Aknin M, Kashman Y, Gauvin-Bialecki A.

J Nat Prod. 2014 Apr 25;77(4):818-23. doi: 10.1021/np4009283. Epub 2014 Mar 6.

PMID:
24601655
15.

Derivatives of salarin A, salarin C and tulearin A--Fascaplysinopsis sp. metabolites.

Zur LG, Bishara A, Aknin M, Neumann D, Ben-Califa N, Kashman Y.

Mar Drugs. 2013 Nov 11;11(11):4487-509. doi: 10.3390/md11114487.

16.

Protective and antioxidant effects of a chalconoid from Pulicaria incisa on brain astrocytes.

Elmann A, Telerman A, Erlank H, Mordechay S, Rindner M, Ofir R, Kashman Y.

Oxid Med Cell Longev. 2013;2013:694398. doi: 10.1155/2013/694398. Epub 2013 Aug 28.

17.

Sterols from the Madagascar sponge Fascaplysinopsis sp.

Aknin M, Gros E, Vacelet J, Kashman Y, Gauvin-Bialecki A.

Mar Drugs. 2010 Dec 17;8(12):2961-75. doi: 10.3390/md8122961.

18.

Recent N-atom containing compounds from indo-pacific invertebrates.

Kashman Y, Bishara A, Aknin M.

Mar Drugs. 2010 Nov 10;8(11):2810-36. doi: 10.3390/md8112810. Review.

19.

Salarin C, a member of the salarin superfamily of marine compounds, is a potent inducer of apoptosis.

Ben-Califa N, Bishara A, Kashman Y, Neumann D.

Invest New Drugs. 2012 Feb;30(1):98-104. doi: 10.1007/s10637-010-9521-4. Epub 2010 Aug 24.

PMID:
20734109
20.

Salaramides A and B; two alpha-oxoamides isolated from the marine sponge Hippospongia sp. (Porifera, Dictyoceratida).

Bensemhoun J, Rudi A, Kashman Y, Gaydou EM, Vacelet J, Aknin M.

Nat Prod Commun. 2010 Feb;5(2):259-60.

PMID:
20334139
21.

Auroside, a xylosyl-sterol, and patusterol A and B, two hydroxylated sterols, from two soft corals Eleutherobia aurea and Lobophytum patulum.

Yeffet D, Rudi A, Ketzinel S, Benayahu Y, Kashman Y.

Nat Prod Commun. 2010 Feb;5(2):205-10.

PMID:
20334128
22.

Plakinamine L: a new steroidal alkaloid from the marine sponge Corticium sp.

Aknin M, Rudi A, Kashman Y, Vacelet J, Gaydou EM.

Nat Prod Commun. 2010 Jan;5(1):33-4.

PMID:
20184015
23.

Isohalitulin and haliclorensins B and C, three marine alkaloids from Haliclona tulearensis.

Sorek H, Rudi A, Aknin M, Gaydou EM, Kashman Y.

J Nat Prod. 2010 Mar 26;73(3):456-8. doi: 10.1021/np900500c.

PMID:
19894692
24.

Tausalarin C: a new bioactive marine sponge-derived nitrogenous bismacrolide.

Bishara A, Rudi A, Goldberg I, Aknin M, Neumann D, Ben-Califa N, Kashman Y.

Org Lett. 2009 Aug 20;11(16):3538-41. doi: 10.1021/ol9011019.

PMID:
19627102
25.

Saldedines A and B, dibromo proaporphine alkaloids from a Madagascan tunicate.

Sorek H, Rudi A, Goldberg I, Aknin M, Kashman Y.

J Nat Prod. 2009 Apr;72(4):784-6. doi: 10.1021/np800714k.

PMID:
19216520
26.

Taumycins A and B, two bioactive lipodepsipeptides from the Madagascar sponge Fascaplysinopsis sp.

Bishara A, Rudi A, Aknin M, Neumann D, Ben-Califa N, Kashman Y.

Org Lett. 2008 Oct 2;10(19):4307-9. doi: 10.1021/ol801750y. Epub 2008 Sep 10.

PMID:
18781810
27.

Flexusines A and B and epimukulol from the soft coral Sarcophyton flexuosum.

Bensemhoun J, Rudi A, Bombarda I, Gaydou EM, Kashman Y, Aknin M.

J Nat Prod. 2008 Jul;71(7):1262-4. doi: 10.1021/np070691d. Epub 2008 May 29.

PMID:
18507471
28.

Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain.

Moussaieff A, Rimmerman N, Bregman T, Straiker A, Felder CC, Shoham S, Kashman Y, Huang SM, Lee H, Shohami E, Mackie K, Caterina MJ, Walker JM, Fride E, Mechoulam R.

FASEB J. 2008 Aug;22(8):3024-34. doi: 10.1096/fj.07-101865. Epub 2008 May 20.

29.

Nardosinanols A-I and lemnafricanol, sesquiterpenes from several soft corals, Lemnalia sp., Paralemnalia clavata, Lemnalia africana, and Rhytisma fulvum fulvum.

Bishara A, Yeffet D, Sisso M, Shmul G, Schleyer M, Benayahu Y, Rudi A, Kashman Y.

J Nat Prod. 2008 Mar;71(3):375-80. doi: 10.1021/np070550b. Epub 2008 Feb 5.

PMID:
18247571
30.

Salarins a and B and tulearin a: new cytotoxic sponge-derived macrolides.

Bishara A, Rudi A, Aknin M, Neumann D, Ben-Califa N, Kashman Y.

Org Lett. 2008 Jan 17;10(2):153-6. Epub 2007 Dec 18.

PMID:
18085784
31.

Three biscembranoids and their monomeric counterpart cembranoid, a biogenetic Diels-Alder precursor, from the soft coral Sarcophyton elegans.

Bishara A, Rudi A, Benayahu Y, Kashman Y.

J Nat Prod. 2007 Dec;70(12):1951-4. Epub 2007 Nov 16.

PMID:
18004813
32.

Incensole acetate, a novel anti-inflammatory compound isolated from Boswellia resin, inhibits nuclear factor-kappa B activation.

Moussaieff A, Shohami E, Kashman Y, Fride E, Schmitz ML, Renner F, Fiebich BL, Munoz E, Ben-Neriah Y, Mechoulam R.

Mol Pharmacol. 2007 Dec;72(6):1657-64. Epub 2007 Sep 25.

PMID:
17895408
33.

Nuttingins A-F and malonganenones D-H, tetraprenylated alkaloids from the Tanzanian gorgonian Euplexaura nuttingi.

Sorek H, Rudi A, Benayahu Y, Ben-Califa N, Neumann D, Kashman Y.

J Nat Prod. 2007 Jul;70(7):1104-9. Epub 2007 Jun 16.

PMID:
17571903
34.

Negombins A-I, new chlorinated polyfunctional diterpenoids from the marine sponge Negombata species.

Rudi A, Benayahu Y, Kashman Y.

Org Lett. 2007 Jun 7;9(12):2337-40. Epub 2007 May 16.

PMID:
17503835
35.

High-throughput screening of cellular features using high-resolution light-microscopy; application for profiling drug effects on cell adhesion.

Paran Y, Ilan M, Kashman Y, Goldstein S, Liron Y, Geiger B, Kam Z.

J Struct Biol. 2007 May;158(2):233-43. Epub 2007 Jan 17.

PMID:
17321150
36.

Effects of natural and novel synthetic jasmonates in experimental metastatic melanoma.

Reischer D, Heyfets A, Shimony S, Nordenberg J, Kashman Y, Flescher E.

Br J Pharmacol. 2007 Mar;150(6):738-49. Epub 2007 Feb 12.

37.

Isolation and Identification of a New Antifungal Sesquiterpene Lactone from Inula viscosa.

Maoz M, Kashman Y, Neeman I.

Planta Med. 1999 Apr;65(3):281-2.

PMID:
17260308
38.

beta-turn mimetic: synthesis of cyclic thioenamino peptides.

Pappo D, Kashman Y.

Org Lett. 2006 Mar 16;8(6):1177-9.

PMID:
16524297
39.

Synthesis of cyclic endiamino peptides.

Pappo D, Vartanian M, Lang S, Kashman Y.

J Am Chem Soc. 2005 Jun 1;127(21):7682-3.

PMID:
15913350
40.

Antifungal effect and possible mode of activity of a compound from the marine sponge Dysidea herbacea.

Sionov E, Roth D, Sandovsky-Losica H, Kashman Y, Rudi A, Chill L, Berdicevsky I, Segal E.

J Infect. 2005 Jun;50(5):453-60.

PMID:
15907556
41.

Generation of a novel anti-geldanamycin antibody.

Barzilay E, Ben-Califa N, Shahar M, Kashman Y, Neumann D.

Biochem Biophys Res Commun. 2005 May 6;330(2):561-4.

PMID:
15796919
42.

Mycgranol, a new diterpene from the marine sponge Mycale aff. graveleyi.

Rudi A, Benayahu Y, Kashman Y.

J Nat Prod. 2005 Feb;68(2):280-1.

PMID:
15730263
43.

Eunicellin diterpenes from two Kenyan soft corals.

Chill L, Berrer N, Benayahu Y, Kashman Y.

J Nat Prod. 2005 Jan;68(1):19-25.

PMID:
15679311
44.

Synthesis of 9-substituted tetrahydrodiazepinopurines: studies toward the total synthesis of asmarines.

Pappo D, Shimony S, Kashman Y.

J Org Chem. 2005 Jan 7;70(1):199-206.

PMID:
15624923
45.

Asmarines I, J, and K and nosyberkol: four new compounds from the marine sponge Raspailia sp.

Rudi A, Aknin M, Gaydou E, Kashman Y.

J Nat Prod. 2004 Nov;67(11):1932-5.

PMID:
15568794
46.

Likonides A and B: new ansa farnesyl quinols from the marine sponge Hyatella sp.

Rudi A, Benayahu Y, Kashman Y.

Org Lett. 2004 Oct 28;6(22):4013-6.

PMID:
15496087
47.

AK37: the first pyridoacridine described capable of stabilizing the topoisomerase I cleavable complex.

Marshall KM, Holden JA, Koller A, Kashman Y, Copp BR, Barrows LR.

Anticancer Drugs. 2004 Oct;15(9):907-13.

PMID:
15457132
48.

Isoprenoids of the soft coral Sarcophyton glaucum: Nyalolide, a new biscembranoid, and other terpenoids.

Feller M, Rudi A, Berer N, Goldberg I, Stein Z, Benayahu Y, Schleyer M, Kashman Y.

J Nat Prod. 2004 Aug;67(8):1303-8.

PMID:
15332846
49.

Callynormine A, a new marine cyclic peptide of a novel class.

Berer N, Rudi A, Goldberg I, Benayahu Y, Kashman Y.

Org Lett. 2004 Jul 22;6(15):2543-5.

PMID:
15255686
50.

Kitungolides A, B, and C, new diterpenes from a soft coral of a new genus.

Chill L, Rudi A, Benayahu Y, Schleyer M, Kashman Y.

Org Lett. 2004 Mar 4;6(5):755-8.

PMID:
14986967

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