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Items: 22


Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth.

Nagdas S, Kashatus JA, Nascimento A, Hussain SS, Trainor RE, Pollock SR, Adair SJ, Michaels AD, Sesaki H, Stelow EB, Bauer TW, Kashatus DF.

Cell Rep. 2019 Aug 13;28(7):1845-1859.e5. doi: 10.1016/j.celrep.2019.07.031.


RalA and RalB relocalization to depolarized mitochondria depends on clathrin-mediated endocytosis and facilitates TBK1 activation.

Pollock SR, Schinlever AR, Rohani A, Kashatus JA, Kashatus DF.

PLoS One. 2019 Apr 17;14(4):e0214764. doi: 10.1371/journal.pone.0214764. eCollection 2019.


MDVs: Spare the SOD and Spoil the Bug.

Hussain SS, Kashatus DF.

Cell Host Microbe. 2018 Nov 14;24(5):616-618. doi: 10.1016/j.chom.2018.10.013.


Mitochondrial protein S-nitrosation protects against ischemia reperfusion-induced denervation at neuromuscular junction in skeletal muscle.

Wilson RJ, Drake JC, Cui D, Lewellen BM, Fisher CC, Zhang M, Kashatus DF, Palmer LA, Murphy MP, Yan Z.

Free Radic Biol Med. 2018 Mar;117:180-190. doi: 10.1016/j.freeradbiomed.2018.02.006. Epub 2018 Feb 9.


Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy.

Wilson RJ, Drake JC, Cui D, Zhang M, Perry HM, Kashatus JA, Kusminski CM, Scherer PE, Kashatus DF, Okusa MD, Yan Z.

Mitochondrion. 2019 Jan;44:20-26. doi: 10.1016/j.mito.2017.12.008. Epub 2017 Dec 20.


Dynamin-Related Protein 1 Deficiency Promotes Recovery from AKI.

Perry HM, Huang L, Wilson RJ, Bajwa A, Sesaki H, Yan Z, Rosin DL, Kashatus DF, Okusa MD.

J Am Soc Nephrol. 2018 Jan;29(1):194-206. doi: 10.1681/ASN.2017060659. Epub 2017 Oct 30.


The regulation of tumor cell physiology by mitochondrial dynamics.

Kashatus DF.

Biochem Biophys Res Commun. 2018 May 27;500(1):9-16. doi: 10.1016/j.bbrc.2017.06.192. Epub 2017 Jul 1. Review.


The Interplay between Oncogenic Signaling Networks and Mitochondrial Dynamics.

Nagdas S, Kashatus DF.

Antioxidants (Basel). 2017 May 17;6(2). pii: E33. doi: 10.3390/antiox6020033. Review.


Label-Free Quantification of Intracellular Mitochondrial Dynamics Using Dielectrophoresis.

Rohani A, Moore JH, Kashatus JA, Sesaki H, Kashatus DF, Swami NS.

Anal Chem. 2017 Jun 6;89(11):5757-5764. doi: 10.1021/acs.analchem.6b04666. Epub 2017 May 15.


Mitochondrial control by DRP1 in brain tumor initiating cells.

Xie Q, Wu Q, Horbinski CM, Flavahan WA, Yang K, Zhou W, Dombrowski SM, Huang Z, Fang X, Shi Y, Ferguson AN, Kashatus DF, Bao S, Rich JN.

Nat Neurosci. 2015 Apr;18(4):501-10. doi: 10.1038/nn.3960. Epub 2015 Mar 2.


Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth.

Kashatus JA, Nascimento A, Myers LJ, Sher A, Byrne FL, Hoehn KL, Counter CM, Kashatus DF.

Mol Cell. 2015 Feb 5;57(3):537-51. doi: 10.1016/j.molcel.2015.01.002.


An in vitro system to evaluate the scaffold function of the RalA effector protein RalBP1.

Kashatus DF.

Methods Mol Biol. 2014;1120:207-16. doi: 10.1007/978-1-62703-791-4_14.


Ral GTPases in tumorigenesis: emerging from the shadows.

Kashatus DF.

Exp Cell Res. 2013 Sep 10;319(15):2337-42. doi: 10.1016/j.yexcr.2013.06.020. Epub 2013 Jul 2. Review.


Targeting eNOS in pancreatic cancer.

Lampson BL, Kendall SD, Ancrile BB, Morrison MM, Shealy MJ, Barrientos KS, Crowe MS, Kashatus DF, White RR, Gurley SB, Cardona DM, Counter CM.

Cancer Res. 2012 Sep 1;72(17):4472-82. doi: 10.1158/0008-5472.CAN-12-0057. Epub 2012 Jun 27.


Breaking up is hard to do: RalA, mitochondrial fission and cancer.

Kashatus DF, Counter CM.

Small GTPases. 2011 Nov 1;2(6):329-333.


RALA and RALBP1 regulate mitochondrial fission at mitosis.

Kashatus DF, Lim KH, Brady DC, Pershing NL, Cox AD, Counter CM.

Nat Cell Biol. 2011 Aug 7;13(9):1108-15. doi: 10.1038/ncb2310.


Ral activation promotes melanomagenesis.

Zipfel PA, Brady DC, Kashatus DF, Ancrile BD, Tyler DS, Counter CM.

Oncogene. 2010 Aug 26;29(34):4859-64. doi: 10.1038/onc.2010.224. Epub 2010 Jun 21.


cPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatis.

Vignola MJ, Kashatus DF, Taylor GA, Counter CM, Valdivia RH.

J Biol Chem. 2010 Jul 9;285(28):21625-35. doi: 10.1074/jbc.M110.103010. Epub 2010 May 7.


Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA.

Lim KH, Brady DC, Kashatus DF, Ancrile BB, Der CJ, Cox AD, Counter CM.

Mol Cell Biol. 2010 Jan;30(2):508-23. doi: 10.1128/MCB.00916-08. Epub 2009 Nov 9.


Tumour maintenance is mediated by eNOS.

Lim KH, Ancrile BB, Kashatus DF, Counter CM.

Nature. 2008 Apr 3;452(7187):646-9. doi: 10.1038/nature06778. Epub 2008 Mar 16.


NF-kappa B and I kappa B alpha are found in the mitochondria. Evidence for regulation of mitochondrial gene expression by NF-kappa B.

Cogswell PC, Kashatus DF, Keifer JA, Guttridge DC, Reuther JY, Bristow C, Roy S, Nicholson DW, Baldwin AS Jr.

J Biol Chem. 2003 Jan 31;278(5):2963-8. Epub 2002 Nov 13.

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