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Items: 13

1.

Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 to Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution.

Bharadwaj U, Kasembeli MM, Robinson P, Tweardy DJ.

Pharmacol Rev. 2020 Apr;72(2):486-526. doi: 10.1124/pr.119.018440. Review.

PMID:
32198236
2.

Correction: Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma.

Bharadwaj U, Eckols TK, Xu X, Kasembeli MM, Chen Y, Adachi M, Song Y, Mo Q, Lai SY, Tweardy DJ.

Oncotarget. 2019 Feb 22;10(16):1603. doi: 10.18632/oncotarget.26743. eCollection 2019 Feb 22.

3.

Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment.

Kasembeli MM, Bharadwaj U, Robinson P, Tweardy DJ.

Int J Mol Sci. 2018 Aug 5;19(8). pii: E2299. doi: 10.3390/ijms19082299. Review.

4.

Protein stabilization improves STAT3 function in autosomal dominant hyper-IgE syndrome.

Bocchini CE, Nahmod K, Katsonis P, Kim S, Kasembeli MM, Freeman A, Lichtarge O, Makedonas G, Tweardy DJ.

Blood. 2016 Dec 29;128(26):3061-3072. doi: 10.1182/blood-2016-02-702373. Epub 2016 Oct 31.

5.

Chaperonin TRiC/CCT Recognizes Fusion Oncoprotein AML1-ETO through Subunit-Specific Interactions.

Roh SH, Kasembeli MM, Galaz-Montoya JG, Chiu W, Tweardy DJ.

Biophys J. 2016 Jun 7;110(11):2377-2385. doi: 10.1016/j.bpj.2016.04.045.

6.

Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma.

Bharadwaj U, Eckols TK, Xu X, Kasembeli MM, Chen Y, Adachi M, Song Y, Mo Q, Lai SY, Tweardy DJ.

Oncotarget. 2016 May 3;7(18):26307-30. doi: 10.18632/oncotarget.8368. Erratum in: Oncotarget. 2019 Feb 22;10(16):1603.

7.

Rhodium(II) Proximity-Labeling Identifies a Novel Target Site on STAT3 for Inhibitors with Potent Anti-Leukemia Activity.

Minus MB, Liu W, Vohidov F, Kasembeli MM, Long X, Krueger MJ, Stevens A, Kolosov MI, Tweardy DJ, Sison EA, Redell MS, Ball ZT.

Angew Chem Int Ed Engl. 2015 Oct 26;54(44):13085-9. doi: 10.1002/anie.201506889. Epub 2015 Sep 7.

8.

Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer.

Lewis KM, Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Fridley C, Siller R, Tweardy DJ.

Lung Cancer. 2015 Nov;90(2):182-90. doi: 10.1016/j.lungcan.2015.09.014. Epub 2015 Sep 15.

9.

Monoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer.

Bharadwaj U, Kasembeli MM, Eckols TK, Kolosov M, Lang P, Christensen K, Edwards DP, Tweardy DJ.

Cancers (Basel). 2014 Sep 29;6(4):2012-34. doi: 10.3390/cancers6042012.

10.

Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.

Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Adam A, Torres D, Zhang X, Dobrolecki LE, Wei W, Lewis MT, Dave B, Chang JC, Landis MD, Creighton CJ, Mancini MA, Tweardy DJ.

Oncogene. 2015 Mar 12;34(11):1341-53. doi: 10.1038/onc.2014.72. Epub 2014 Mar 31.

11.

Contribution of chaperones to STAT pathway signaling.

Bocchini CE, Kasembeli MM, Roh SH, Tweardy DJ.

JAKSTAT. 2014 Oct 30;3(3):e970459. doi: 10.4161/21623988.2014.970459. eCollection 2014. Review.

12.

Chemical probes that competitively and selectively inhibit Stat3 activation.

Xu X, Kasembeli MM, Jiang X, Tweardy BJ, Tweardy DJ.

PLoS One. 2009;4(3):e4783. doi: 10.1371/journal.pone.0004783. Epub 2009 Mar 10.

13.

SH2 domain binding to phosphopeptide ligands: potential for drug targeting.

Kasembeli MM, Xu X, Tweardy DJ.

Front Biosci (Landmark Ed). 2009 Jan 1;14:1010-22. Review.

PMID:
19273114

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