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Items: 1 to 50 of 61

1.

Plant chemical genetics reveals colistin sulphate as a SA and NPR1-independent PR1 inducer functioning via a p38-like kinase pathway.

Halder V, Suliman MNS, Kaschani F, Kaiser M.

Sci Rep. 2019 Aug 1;9(1):11196. doi: 10.1038/s41598-019-47526-5.

2.

Triazine Probes Target Ascorbate Peroxidases in Plants.

Morimoto K, Cole KS, Kourelis J, Witt CH, Brown D, Krahn D, Stegmann M, Kaschani F, Kaiser M, Burton J, Mohammed S, Yamaguchi-Shinozaki K, Weerapana E, van der Hoorn RAL.

Plant Physiol. 2019 Aug;180(4):1848-1859. doi: 10.1104/pp.19.00481. Epub 2019 May 28.

PMID:
31138623
3.

Proteases Underground: Analysis of the Maize Root Apoplast Identifies Organ Specific Papain-Like Cysteine Protease Activity.

Schulze Hüynck J, Kaschani F, van der Linde K, Ziemann S, Müller AN, Colby T, Kaiser M, Misas Villamil JC, Doehlemann G.

Front Plant Sci. 2019 Apr 30;10:473. doi: 10.3389/fpls.2019.00473. eCollection 2019.

4.

Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation.

Weiss-Sadan T, Itzhak G, Kaschani F, Yu Z, Mahameed M, Anaki A, Ben-Nun Y, Merquiol E, Tirosh B, Kessler B, Kaiser M, Blum G.

Mol Cell Proteomics. 2019 Jul;18(7):1330-1344. doi: 10.1074/mcp.RA119.001392. Epub 2019 Apr 22.

5.

Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptides.

Buscaill P, Chandrasekar B, Sanguankiattichai N, Kourelis J, Kaschani F, Thomas EL, Morimoto K, Kaiser M, Preston GM, Ichinose Y, van der Hoorn RAL.

Science. 2019 Apr 12;364(6436). pii: eaav0748. doi: 10.1126/science.aav0748.

PMID:
30975858
6.

Dynamic hydrolase labelling as a marker for seed quality in Arabidopsis seeds.

Viñegra de la Torre N, Kaschani F, Kaiser M, van der Hoorn RAL, Soppe WJJ, Misas Villamil JC.

Biochem J. 2019 Mar 12;476(5):843-857. doi: 10.1042/BCJ20180911.

PMID:
30782971
7.

Activity-based proteomics reveals nine target proteases for the recombinant protein-stabilizing inhibitor SlCYS8 in Nicotiana benthamiana.

Jutras PV, Grosse-Holz F, Kaschani F, Kaiser M, Michaud D, van der Hoorn RAL.

Plant Biotechnol J. 2019 Aug;17(8):1670-1678. doi: 10.1111/pbi.13092. Epub 2019 Mar 14.

8.

Metabolic reconstruction of the genome of candidate Desulfatiglans TRIP_1 and identification of key candidate enzymes for anaerobic phenanthrene degradation.

Kraiselburd I, Brüls T, Heilmann G, Kaschani F, Kaiser M, Meckenstock RU.

Environ Microbiol. 2019 Apr;21(4):1267-1286. doi: 10.1111/1462-2920.14527. Epub 2019 Feb 7.

PMID:
30680888
9.

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

Weith M, Seiler J, van den Boom J, Kracht M, Hülsmann J, Primorac I, Del Pino Garcia J, Kaschani F, Kaiser M, Musacchio A, Bollen M, Meyer H.

Mol Cell. 2018 Nov 15;72(4):766-777.e6. doi: 10.1016/j.molcel.2018.09.020. Epub 2018 Oct 18.

PMID:
30344098
10.

Utilities for Mass Spectrometry Analysis of Proteins (UMSAP): Fast post-processing of mass spectrometry data.

Bravo-Rodriguez K, Hagemeier B, Drescher L, Lorenz M, Rey J, Meltzer M, Kaschani F, Kaiser M, Ehrmann M.

Rapid Commun Mass Spectrom. 2018 Oct 15;32(19):1659-1667. doi: 10.1002/rcm.8243.

PMID:
30062799
11.

Identification of the Natural Product Rotihibin A as a TOR Kinase Signaling Inhibitor by Unbiased Transcriptional Profiling.

Halder V, Oeljeklaus J, Heilmann G, Krahn JH, Liu Y, Xiong Y, Schlicht M, Schillinger J, Kracher B, Ehrmann M, Kombrink E, Kaschani F, Kaiser M.

Chemistry. 2018 Aug 27;24(48):12500-12504. doi: 10.1002/chem.201802647. Epub 2018 Jul 27.

PMID:
29932252
12.

HTRA1-Dependent Cell Cycle Proteomics.

Schillinger J, Severin K, Kaschani F, Kaiser M, Ehrmann M.

J Proteome Res. 2018 Aug 3;17(8):2679-2694. doi: 10.1021/acs.jproteome.8b00129. Epub 2018 Jul 13.

PMID:
29863874
13.

Fermentative Spirochaetes mediate necromass recycling in anoxic hydrocarbon-contaminated habitats.

Dong X, Greening C, Brüls T, Conrad R, Guo K, Blaskowski S, Kaschani F, Kaiser M, Laban NA, Meckenstock RU.

ISME J. 2018 Aug;12(8):2039-2050. doi: 10.1038/s41396-018-0148-3. Epub 2018 May 30.

14.

Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent Probes.

Bongard J, Lorenz M, Vetter IR, Stege P, Porfetye AT, Schmitz AL, Kaschani F, Wolf A, Koch U, Nussbaumer P, Klebl B, Kaiser M, Ehrmann M.

ACS Chem Biol. 2018 May 18;13(5):1307-1312. doi: 10.1021/acschembio.8b00101. Epub 2018 Apr 16.

PMID:
29658704
15.

Multiplex Fluorescent, Activity-Based Protein Profiling Identifies Active α-Glycosidases and Other Hydrolases in Plants.

Husaini AM, Morimoto K, Chandrasekar B, Kelly S, Kaschani F, Palmero D, Jiang J, Kaiser M, Ahrazem O, Overkleeft HS, van der Hoorn RAL.

Plant Physiol. 2018 May;177(1):24-37. doi: 10.1104/pp.18.00250. Epub 2018 Mar 19.

16.

Low Protease Content in Medicago truncatula Cell Cultures Facilitates Recombinant Protein Production.

Santos RB, Chandrasekar B, Mandal MK, Kaschani F, Kaiser M, Both L, van der Hoorn RAL, Schiermeyer A, Abranches R.

Biotechnol J. 2018 Jul;13(7):e1800050. doi: 10.1002/biot.201800050. Epub 2018 Mar 26.

PMID:
29528190
17.

Protease Activities Triggered by Ralstonia solanacearum Infection in Susceptible and Tolerant Tomato Lines.

Planas-Marquès M, Bernardo-Faura M, Paulus J, Kaschani F, Kaiser M, Valls M, van der Hoorn RAL, Coll NS.

Mol Cell Proteomics. 2018 Jun;17(6):1112-1125. doi: 10.1074/mcp.RA117.000052. Epub 2018 Mar 9.

18.

Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in Nicotiana benthamiana.

Grosse-Holz F, Madeira L, Zahid MA, Songer M, Kourelis J, Fesenko M, Ninck S, Kaschani F, Kaiser M, van der Hoorn RAL.

Plant Biotechnol J. 2018 Oct;16(10):1797-1810. doi: 10.1111/pbi.12916. Epub 2018 May 24.

19.

An apoplastic peptide activates salicylic acid signalling in maize.

Ziemann S, van der Linde K, Lahrmann U, Acar B, Kaschani F, Colby T, Kaiser M, Ding Y, Schmelz E, Huffaker A, Holton N, Zipfel C, Doehlemann G.

Nat Plants. 2018 Mar;4(3):172-180. doi: 10.1038/s41477-018-0116-y. Epub 2018 Feb 26.

PMID:
29483684
20.

A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases.

Pöhler R, Krahn JH, van den Boom J, Dobrynin G, Kaschani F, Eggenweiler HM, Zenke FT, Kaiser M, Meyer H.

Angew Chem Int Ed Engl. 2018 Feb 5;57(6):1576-1580. doi: 10.1002/anie.201711429. Epub 2018 Jan 15.

PMID:
29271116
21.

The transcriptome, extracellular proteome and active secretome of agroinfiltrated Nicotiana benthamiana uncover a large, diverse protease repertoire.

Grosse-Holz F, Kelly S, Blaskowski S, Kaschani F, Kaiser M, van der Hoorn RAL.

Plant Biotechnol J. 2018 May;16(5):1068-1084. doi: 10.1111/pbi.12852. Epub 2017 Dec 17.

22.

Turning-ON Proteasomes.

Krahn JH, Kaschani F, Kaiser M.

Cell Chem Biol. 2017 Jun 22;24(6):653-655. doi: 10.1016/j.chembiol.2017.06.005.

23.

Activity-based protein profiling as a robust method for enzyme identification and screening in extremophilic Archaea.

Zweerink S, Kallnik V, Ninck S, Nickel S, Verheyen J, Blum M, Wagner A, Feldmann I, Sickmann A, Albers SV, Bräsen C, Kaschani F, Siebers B, Kaiser M.

Nat Commun. 2017 May 8;8:15352. doi: 10.1038/ncomms15352.

24.

The Root Growth-Regulating Brevicompanine Natural Products Modulate the Plant Circadian Clock.

de Montaigu A, Oeljeklaus J, Krahn JH, Suliman MNS, Halder V, de Ansorena E, Nickel S, Schlicht M, Plíhal O, Kubiasová K, Radová L, Kracher B, Tóth R, Kaschani F, Coupland G, Kombrink E, Kaiser M.

ACS Chem Biol. 2017 Jun 16;12(6):1466-1471. doi: 10.1021/acschembio.6b00978. Epub 2017 Apr 19.

25.

Proteasome Activity Profiling Uncovers Alteration of Catalytic β2 and β5 Subunits of the Stress-Induced Proteasome during Salinity Stress in Tomato Roots.

Kovács J, Poór P, Kaschani F, Chandrasekar B, Hong TN, Misas-Villamil JC, Xin BT, Kaiser M, Overkleeft HS, Tari I, van der Hoorn RA.

Front Plant Sci. 2017 Feb 3;8:107. doi: 10.3389/fpls.2017.00107. eCollection 2017.

26.

Subunit-selective proteasome activity profiling uncovers uncoupled proteasome subunit activities during bacterial infections.

Misas-Villamil JC, van der Burgh AM, Grosse-Holz F, Bach-Pages M, Kovács J, Kaschani F, Schilasky S, Emon AE, Ruben M, Kaiser M, Overkleeft HS, van der Hoorn RA.

Plant J. 2017 Apr;90(2):418-430. doi: 10.1111/tpj.13494. Epub 2017 Mar 14.

27.

Major Cys protease activities are not essential for senescence in individually darkened Arabidopsis leaves.

Pružinská A, Shindo T, Niessen S, Kaschani F, Tóth R, Millar AH, van der Hoorn RA.

BMC Plant Biol. 2017 Jan 6;17(1):4. doi: 10.1186/s12870-016-0955-5.

28.

Quantitative Proteomics Reveals Ecophysiological Effects of Light and Silver Stress on the Mixotrophic Protist Poterioochromonas malhamensis.

Beisser D, Kaschani F, Graupner N, Grossmann L, Jensen M, Ninck S, Schulz F, Rahmann S, Boenigk J, Kaiser M.

PLoS One. 2017 Jan 5;12(1):e0168183. doi: 10.1371/journal.pone.0168183. eCollection 2017.

29.

Activity-Based Protein Profiling with Natural Product-Derived Chemical Probes in Human Cell Lysates.

Zweerink S, Pollmann T, Ninck S, Kaschani F, Kaiser M.

Methods Mol Biol. 2017;1491:23-46.

PMID:
27778279
30.

VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair.

van den Boom J, Wolf M, Weimann L, Schulze N, Li F, Kaschani F, Riemer A, Zierhut C, Kaiser M, Iliakis G, Funabiki H, Meyer H.

Mol Cell. 2016 Oct 6;64(1):189-198. doi: 10.1016/j.molcel.2016.08.037.

31.

Screen of Non-annotated Small Secreted Proteins of Pseudomonas syringae Reveals a Virulence Factor That Inhibits Tomato Immune Proteases.

Shindo T, Kaschani F, Yang F, Kovács J, Tian F, Kourelis J, Hong TN, Colby T, Shabab M, Chawla R, Kumari S, Ilyas M, Hörger AC, Alfano JR, van der Hoorn RA.

PLoS Pathog. 2016 Sep 7;12(9):e1005874. doi: 10.1371/journal.ppat.1005874. eCollection 2016 Sep.

32.

Mesenchymal Stem Cell Therapy Protects Lungs from Radiation-Induced Endothelial Cell Loss by Restoring Superoxide Dismutase 1 Expression.

Klein D, Steens J, Wiesemann A, Schulz F, Kaschani F, Röck K, Yamaguchi M, Wirsdörfer F, Kaiser M, Fischer JW, Stuschke M, Jendrossek V.

Antioxid Redox Signal. 2017 Apr 10;26(11):563-582. doi: 10.1089/ars.2016.6748. Epub 2016 Nov 14.

33.

Capture of endogenously biotinylated proteins from Pseudomonas aeruginosa displays unexpected downregulation of LiuD upon iron nutrition.

Kaschani F, Wei Q, Dingemans J, van der Hoorn RA, Cornelis P, Kaiser M.

Bioorg Med Chem. 2016 Aug 1;24(15):3330-5. doi: 10.1016/j.bmc.2016.04.051. Epub 2016 Apr 26.

PMID:
27160053
34.

A novel quenched fluorescent activity-based probe reveals caspase-3 activity in the endoplasmic reticulum during apoptosis.

Shaulov-Rotem Y, Merquiol E, Weiss-Sadan T, Moshel O, Salpeter S, Shabat D, Kaschani F, Kaiser M, Blum G.

Chem Sci. 2016 Feb 1;7(2):1322-1337. doi: 10.1039/c5sc03207e. Epub 2015 Nov 11.

35.

Determinants of amyloid fibril degradation by the PDZ protease HTRA1.

Poepsel S, Sprengel A, Sacca B, Kaschani F, Kaiser M, Gatsogiannis C, Raunser S, Clausen T, Ehrmann M.

Nat Chem Biol. 2015 Nov;11(11):862-9. doi: 10.1038/nchembio.1931. Epub 2015 Oct 5.

PMID:
26436840
36.

Functional Divergence of Two Secreted Immune Proteases of Tomato.

Ilyas M, Hörger AC, Bozkurt TO, van den Burg HA, Kaschani F, Kaiser M, Belhaj K, Smoker M, Joosten MH, Kamoun S, van der Hoorn RA.

Curr Biol. 2015 Aug 31;25(17):2300-6. doi: 10.1016/j.cub.2015.07.030. Epub 2015 Aug 20.

37.

Chemoproteomic Evaluation of the Polyacetylene Callyspongynic Acid.

Nickel S, Serwa RA, Kaschani F, Ninck S, Zweerink S, Tate EW, Kaiser M.

Chemistry. 2015 Jul 20;21(30):10721-8. doi: 10.1002/chem.201500934. Epub 2015 Jun 16.

38.

Chemical proteomics versus leishmaniasis.

Ehrmann M, Kaschani F, Kaiser M.

Chem Biol. 2015 Mar 19;22(3):309-10. doi: 10.1016/j.chembiol.2015.03.001.

39.

Peptidyl succinimidyl peptides as taspase 1 inhibitors.

van den Boom J, Mamić M, Baccelliere D, Zweerink S, Kaschani F, Knauer S, Bayer P, Kaiser M.

Chembiochem. 2014 Oct 13;15(15):2233-7. doi: 10.1002/cbic.201402108. Epub 2014 Aug 21.

PMID:
25146997
40.

Profiling protein kinases and other ATP binding proteins in Arabidopsis using Acyl-ATP probes.

Villamor JG, Kaschani F, Colby T, Oeljeklaus J, Zhao D, Kaiser M, Patricelli MP, van der Hoorn RA.

Mol Cell Proteomics. 2013 Sep;12(9):2481-96. doi: 10.1074/mcp.M112.026278. Epub 2013 May 29.

41.

Pseudomonas syringae pv. syringae uses proteasome inhibitor syringolin A to colonize from wound infection sites.

Misas-Villamil JC, Kolodziejek I, Crabill E, Kaschani F, Niessen S, Shindo T, Kaiser M, Alfano JR, van der Hoorn RA.

PLoS Pathog. 2013 Mar;9(3):e1003281. doi: 10.1371/journal.ppat.1003281. Epub 2013 Mar 28.

42.

A substrate-inspired probe monitors translocation, activation, and subcellular targeting of bacterial type III effector protease AvrPphB.

Lu H, Wang Z, Shabab M, Oeljeklaus J, Verhelst SH, Kaschani F, Kaiser M, Bogyo M, van der Hoorn RA.

Chem Biol. 2013 Feb 21;20(2):168-76. doi: 10.1016/j.chembiol.2012.11.007.

43.

Streamlining chemical probe discovery: libraries of "fully functionalized" small molecules for phenotypic screening.

Oeljeklaus J, Kaschani F, Kaiser M.

Angew Chem Int Ed Engl. 2013 Jan 28;52(5):1368-70. doi: 10.1002/anie.201207306. Epub 2012 Dec 20. No abstract available.

PMID:
23281006
44.

The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains.

Stolze SC, Deu E, Kaschani F, Li N, Florea BI, Richau KH, Colby T, van der Hoorn RA, Overkleeft HS, Bogyo M, Kaiser M.

Chem Biol. 2012 Dec 21;19(12):1546-55. doi: 10.1016/j.chembiol.2012.09.020.

45.

Activity profiling of vacuolar processing enzymes reveals a role for VPE during oomycete infection.

Misas-Villamil JC, Toenges G, Kolodziejek I, Sadaghiani AM, Kaschani F, Colby T, Bogyo M, van der Hoorn RA.

Plant J. 2013 Feb;73(4):689-700. doi: 10.1111/tpj.12062. Epub 2012 Dec 28.

46.

Identification of a selective, activity-based probe for glyceraldehyde 3-phosphate dehydrogenases.

Kaschani F, Clerc J, Krahn D, Bier D, Hong TN, Ottmann C, Niessen S, Colby T, van der Hoorn RA, Kaiser M.

Angew Chem Int Ed Engl. 2012 May 21;51(21):5230-3. doi: 10.1002/anie.201107276. Epub 2012 Apr 5. No abstract available.

PMID:
22489074
47.

A maize cystatin suppresses host immunity by inhibiting apoplastic cysteine proteases.

van der Linde K, Hemetsberger C, Kastner C, Kaschani F, van der Hoorn RA, Kumlehn J, Doehlemann G.

Plant Cell. 2012 Mar;24(3):1285-300. doi: 10.1105/tpc.111.093732. Epub 2012 Mar 27.

48.

Post-translational regulation and trafficking of the granulin-containing protease RD21 of Arabidopsis thaliana.

Gu C, Shabab M, Strasser R, Wolters PJ, Shindo T, Niemer M, Kaschani F, Mach L, van der Hoorn RA.

PLoS One. 2012;7(3):e32422. doi: 10.1371/journal.pone.0032422. Epub 2012 Mar 2.

49.

Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics.

Richau KH, Kaschani F, Verdoes M, Pansuriya TC, Niessen S, Stüber K, Colby T, Overkleeft HS, Bogyo M, Van der Hoorn RA.

Plant Physiol. 2012 Apr;158(4):1583-99. doi: 10.1104/pp.112.194001. Epub 2012 Feb 27.

50.

Activity-based protein profiling of infected plants.

Kaschani F, Gu C, van der Hoorn RA.

Methods Mol Biol. 2012;835:47-59. doi: 10.1007/978-1-61779-501-5_3.

PMID:
22183646

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