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Items: 1 to 50 of 67

1.

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.

Zammit NW, Siggs OM, Gray PE, Horikawa K, Langley DB, Walters SN, Daley SR, Loetsch C, Warren J, Yap JY, Cultrone D, Russell A, Malle EK, Villanueva JE, Cowley MJ, Gayevskiy V, Dinger ME, Brink R, Zahra D, Chaudhri G, Karupiah G, Whittle B, Roots C, Bertram E, Yamada M, Jeelall Y, Enders A, Clifton BE, Mabbitt PD, Jackson CJ, Watson SR, Jenne CN, Lanier LL, Wiltshire T, Spitzer MH, Nolan GP, Schmitz F, Aderem A, Porebski BT, Buckle AM, Abbott DW, Ziegler JB, Craig ME, Benitez-Aguirre P, Teo J, Tangye SG, King C, Wong M, Cox MP, Phung W, Tang J, Sandoval W, Wertz IE, Christ D, Goodnow CC, Grey ST.

Nat Immunol. 2019 Oct;20(10):1299-1310. doi: 10.1038/s41590-019-0492-0. Epub 2019 Sep 18.

PMID:
31534238
2.

Viral Replicative Capacity, Antigen Availability via Hematogenous Spread, and High TFH:TFR Ratios Drive Induction of Potent Neutralizing Antibody Responses.

Eldi P, Chaudhri G, Nutt SL, Newsome TP, Karupiah G.

J Virol. 2019 Mar 5;93(6). pii: e01795-18. doi: 10.1128/JVI.01795-18. Print 2019 Mar 15.

3.

Propagation and Purification of Ectromelia Virus.

Chaudhri G, Kaladimou G, Pandey P, Karupiah G.

Curr Protoc Microbiol. 2018 Nov;51(1):e65. doi: 10.1002/cpmc.65. Epub 2018 Oct 3.

PMID:
30281950
4.

LMP2 immunoproteasome promotes lymphocyte survival by degrading apoptotic BH3-only proteins.

Zanker D, Pang K, Oveissi S, Lu C, Faou P, Nowell C, Mbogo GW, Carotta S, Quillici C, Karupiah G, Hibbs ML, Nutt SL, Neeson P, Puthalakath H, Chen W.

Immunol Cell Biol. 2018 Oct;96(9):981-993. doi: 10.1111/imcb.12163. Epub 2018 Jun 3.

PMID:
29738610
5.

Loss of Actin-Based Motility Impairs Ectromelia Virus Release In Vitro but Is Not Critical to Spread In Vivo.

Duncan ML, Horsington J, Eldi P, Al Rumaih Z, Karupiah G, Newsome TP.

Viruses. 2018 Mar 5;10(3). pii: E111. doi: 10.3390/v10030111.

6.

Evidence for Persistence of Ectromelia Virus in Inbred Mice, Recrudescence Following Immunosuppression and Transmission to Naïve Mice.

Sakala IG, Chaudhri G, Scalzo AA, Eldi P, Newsome TP, Buller RM, Karupiah G.

PLoS Pathog. 2015 Dec 23;11(12):e1005342. doi: 10.1371/journal.ppat.1005342. eCollection 2015 Dec.

7.

Deficiency in Th2 cytokine responses exacerbate orthopoxvirus infection.

Sakala IG, Chaudhri G, Eldi P, Buller RM, Karupiah G.

PLoS One. 2015 Mar 9;10(3):e0118685. doi: 10.1371/journal.pone.0118685. eCollection 2015.

8.

A natural genetic variant of granzyme B confers lethality to a common viral infection.

Andoniou CE, Sutton VR, Wikstrom ME, Fleming P, Thia KY, Matthews AY, Kaiserman D, Schuster IS, Coudert JD, Eldi P, Chaudhri G, Karupiah G, Bird PI, Trapani JA, Degli-Esposti MA.

PLoS Pathog. 2014 Dec 11;10(12):e1004526. doi: 10.1371/journal.ppat.1004526. eCollection 2014 Dec.

9.

Vaccine-induced protection against orthopoxvirus infection is mediated through the combined functions of CD4 T cell-dependent antibody and CD8 T cell responses.

Chaudhri G, Tahiliani V, Eldi P, Karupiah G.

J Virol. 2015 Feb;89(3):1889-99. doi: 10.1128/JVI.02572-14. Epub 2014 Nov 26.

10.

A36-dependent actin filament nucleation promotes release of vaccinia virus.

Horsington J, Lynn H, Turnbull L, Cheng D, Braet F, Diefenbach RJ, Whitchurch CB, Karupiah G, Newsome TP.

PLoS Pathog. 2013 Mar;9(3):e1003239. doi: 10.1371/journal.ppat.1003239. Epub 2013 Mar 21.

11.

The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells.

Gatto D, Wood K, Caminschi I, Murphy-Durland D, Schofield P, Christ D, Karupiah G, Brink R.

Nat Immunol. 2013 May;14(5):446-53. doi: 10.1038/ni.2555. Epub 2013 Mar 17. Erratum in: Nat Immunol. 2013 Aug;14(8):876.

PMID:
23502855
12.

The orchestrated functions of innate leukocytes and T cell subsets contribute to humoral immunity, virus control, and recovery from secondary poxvirus challenge.

Tahiliani V, Chaudhri G, Eldi P, Karupiah G.

J Virol. 2013 Apr;87(7):3852-61. doi: 10.1128/JVI.03038-12. Epub 2013 Jan 23.

13.

Breakdown in repression of IFN-γ mRNA leads to accumulation of self-reactive effector CD8+ T cells.

Chang PP, Lee SK, Hu X, Davey G, Duan G, Cho JH, Karupiah G, Sprent J, Heath WR, Bertram EM, Vinuesa CG.

J Immunol. 2012 Jul 15;189(2):701-10. doi: 10.4049/jimmunol.1102432. Epub 2012 Jun 8.

14.

Loss of cytoskeletal transport during egress critically attenuates ectromelia virus infection in vivo.

Lynn H, Horsington J, Ter LK, Han S, Chew YL, Diefenbach RJ, Way M, Chaudhri G, Karupiah G, Newsome TP.

J Virol. 2012 Jul;86(13):7427-43. doi: 10.1128/JVI.06636-11. Epub 2012 Apr 24.

15.

Granzyme B expression by CD8+ T cells is required for the development of experimental cerebral malaria.

Haque A, Best SE, Unosson K, Amante FH, de Labastida F, Anstey NM, Karupiah G, Smyth MJ, Heath WR, Engwerda CR.

J Immunol. 2011 Jun 1;186(11):6148-56. doi: 10.4049/jimmunol.1003955. Epub 2011 Apr 27.

16.

Alternate mechanisms of initial pattern recognition drive differential immune responses to related poxviruses.

O'Gorman WE, Sampath P, Simonds EF, Sikorski R, O'Malley M, Krutzik PO, Chen H, Panchanathan V, Chaudhri G, Karupiah G, Lewis DB, Thorne SH, Nolan GP.

Cell Host Microbe. 2010 Aug 19;8(2):174-85. doi: 10.1016/j.chom.2010.07.008.

17.

Antiviral protection following immunization correlates with humoral but not cell-mediated immunity.

Panchanathan V, Chaudhri G, Karupiah G.

Immunol Cell Biol. 2010 May-Jun;88(4):461-7. doi: 10.1038/icb.2009.110. Epub 2010 Jan 12.

PMID:
20066003
18.

T cell receptor sharing by cytotoxic T lymphocytes facilitates efficient virus control.

Chaudhri G, Quah BJ, Wang Y, Tan AH, Zhou J, Karupiah G, Parish CR.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14984-9. doi: 10.1073/pnas.0906554106. Epub 2009 Aug 18.

19.

IL-12p40 and IL-18 play pivotal roles in orchestrating the cell-mediated immune response to a poxvirus infection.

Wang Y, Chaudhri G, Jackson RJ, Karupiah G.

J Immunol. 2009 Sep 1;183(5):3324-31. doi: 10.4049/jimmunol.0803985. Epub 2009 Aug 5.

20.

Correlates of protective immunity in poxvirus infection: where does antibody stand?

Panchanathan V, Chaudhri G, Karupiah G.

Immunol Cell Biol. 2008 Jan;86(1):80-6. Epub 2007 Oct 9. Review.

PMID:
17923850
21.

Genetic resistance to smallpox: lessons from mousepox.

Karupiah G, Panchanathan V, Sakala IG, Chaudhri G.

Novartis Found Symp. 2007;281:129-36; discussion 136-40, 208-9. Review.

PMID:
17534070
22.

Poxvirus-encoded gamma interferon binding protein dampens the host immune response to infection.

Sakala IG, Chaudhri G, Buller RM, Nuara AA, Bai H, Chen N, Karupiah G.

J Virol. 2007 Apr;81(7):3346-53. Epub 2007 Jan 17.

23.

Immunopathogenesis of poxvirus infections: forecasting the impending storm.

Stanford MM, McFadden G, Karupiah G, Chaudhri G.

Immunol Cell Biol. 2007 Feb-Mar;85(2):93-102. Epub 2007 Jan 16. Review.

PMID:
17228320
24.

Immunopathogenesis of infectious disease: injury and death from friendly fire.

Karupiah G, Chaudhri G.

Immunol Cell Biol. 2007 Jan;85(1):5. No abstract available.

PMID:
17203109
25.
26.

Obligatory requirement for antibody in recovery from a primary poxvirus infection.

Chaudhri G, Panchanathan V, Bluethmann H, Karupiah G.

J Virol. 2006 Jul;80(13):6339-44. Erratum in: J Virol. 2006 Sep;80(17):8844.

27.
28.

Poxvirus CD8+ T-cell determinants and cross-reactivity in BALB/c mice.

Tscharke DC, Woo WP, Sakala IG, Sidney J, Sette A, Moss DJ, Bennink JR, Karupiah G, Yewdell JW.

J Virol. 2006 Jul;80(13):6318-23.

29.

Interferon function is not required for recovery from a secondary poxvirus infection.

Panchanathan V, Chaudhri G, Karupiah G.

Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12921-6. Epub 2005 Aug 25.

30.

Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines.

Tscharke DC, Karupiah G, Zhou J, Palmore T, Irvine KR, Haeryfar SM, Williams S, Sidney J, Sette A, Bennink JR, Yewdell JW.

J Exp Med. 2005 Jan 3;201(1):95-104. Epub 2004 Dec 28.

31.

Acute effects of parainfluenza virus on epithelial electrolyte transport.

Kunzelmann K, König J, Sun J, Markovich D, King NJ, Karupiah G, Young JA, Cook DI.

J Biol Chem. 2004 Nov 19;279(47):48760-6. Epub 2004 Sep 10.

32.

Polarized type 1 cytokine response and cell-mediated immunity determine genetic resistance to mousepox.

Chaudhri G, Panchanathan V, Buller RM, van den Eertwegh AJ, Claassen E, Zhou J, de Chazal R, Laman JD, Karupiah G.

Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):9057-62. Epub 2004 Jun 7.

33.

Cutting edge: conventional CD8 alpha+ dendritic cells are generally involved in priming CTL immunity to viruses.

Belz GT, Smith CM, Eichner D, Shortman K, Karupiah G, Carbone FR, Heath WR.

J Immunol. 2004 Feb 15;172(4):1996-2000.

34.

Enhanced resistance in STAT6-deficient mice to infection with ectromelia virus.

Mahalingam S, Karupiah G, Takeda K, Akira S, Matthaei KI, Foster PS.

Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6812-7. Epub 2001 May 22.

35.

NADPH oxidase, Nramp1 and nitric oxide synthase 2 in the host antimicrobial response.

Karupiah G, Hunt NH, King NJ, Chaudhri G.

Rev Immunogenet. 2000;2(3):387-415. Review.

PMID:
11256747
36.
37.

Interferon-inducible chemokines and immunity to poxvirus infections.

Mahalingam S, Foster PS, Lobigs M, Farber JM, Karupiah G.

Immunol Rev. 2000 Oct;177:127-33. Review.

PMID:
11138770
38.

Transcription of the interferon gamma (IFN-gamma )-inducible chemokine Mig in IFN-gamma-deficient mice.

Mahalingam S, Chaudhri G, Tan CL, John A, Foster PS, Karupiah G.

J Biol Chem. 2001 Mar 9;276(10):7568-74. Epub 2000 Oct 9.

39.

Unexpected effects of pathogens on epithelial Na+ channels.

Kunzelmann K, Beesley A, King N, Karupiah G, Young J, Cook D.

J Korean Med Sci. 2000 Aug;15 Suppl:S59-60. No abstract available.

40.

Influenza virus inhibits amiloride-sensitive Na+ channels in respiratory epithelia.

Kunzelmann K, Beesley AH, King NJ, Karupiah G, Young JA, Cook DI.

Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10282-7.

41.

Modulation of chemokines by poxvirus infections.

Mahalingam S, Karupiah G.

Curr Opin Immunol. 2000 Aug;12(4):409-12. Review.

PMID:
10899024
42.

Techniques for studying murine natural killer cells in defense against viral infection.

Scalzo AA, Farrell HE, Karupiah G.

Methods Mol Biol. 2000;121:163-77. Review. No abstract available.

PMID:
10818725
43.
44.

Chemokines and chemokine receptors in infectious diseases.

Mahalingam S, Karupiah G.

Immunol Cell Biol. 1999 Dec;77(6):469-75. Review.

PMID:
10571666
45.

Analysis of the Th1/Th2 paradigm in transplantation: interferon-gamma deficiency converts Th1-type proislet allograft rejection to a Th2-type xenograft-like response.

Simeonovic CJ, Townsend MJ, Karupiah G, Wilson JD, Zarb JC, Mann DA, Young IG.

Cell Transplant. 1999 Jul-Aug;8(4):365-73.

PMID:
10478716
46.

Inhibition of allergic airway inflammation in mice lacking nitric oxide synthase 2.

Xiong Y, Karupiah G, Hogan SP, Foster PS, Ramsay AJ.

J Immunol. 1999 Jan 1;162(1):445-52.

47.

The interferon-inducible chemokines MuMig and Crg-2 exhibit antiviral activity In vivo.

Mahalingam S, Farber JM, Karupiah G.

J Virol. 1999 Feb;73(2):1479-91.

48.
49.

Identification of nitric oxide synthase 2 as an innate resistance locus against ectromelia virus infection.

Karupiah G, Chen JH, Nathan CF, Mahalingam S, MacMicking JD.

J Virol. 1998 Sep;72(9):7703-6.

50.

Type 1 and type 2 cytokines in antiviral defense.

Karupiah G.

Vet Immunol Immunopathol. 1998 May 15;63(1-2):105-9. Review.

PMID:
9656445

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