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Items: 14

1.

Optical approaches for single-cell and subcellular analysis of GPCR-G protein signaling.

Kankanamge D, Ratnayake K, Senarath K, Tennakoon M, Harmon E, Karunarathne A.

Anal Bioanal Chem. 2019 Mar 30. doi: 10.1007/s00216-019-01774-6. [Epub ahead of print] Review.

PMID:
30927013
2.

G protein αq exerts expression level-dependent distinct signaling paradigms.

Kankanamge D, Tennakoon M, Weerasinghe A, Cedeno-Rosario L, Chadee DN, Karunarathne A.

Cell Signal. 2019 Jun;58:34-43. doi: 10.1016/j.cellsig.2019.02.006. Epub 2019 Mar 5.

PMID:
30849518
3.

Statins Perturb Gβγ Signaling and Cell Behavior in a Gγ Subtype Dependent Manner.

Tennakoon M, Kankanamge D, Senarath K, Fasih Z, Karunarathne A.

Mol Pharmacol. 2019 Apr;95(4):361-375. doi: 10.1124/mol.118.114710. Epub 2019 Feb 14.

PMID:
30765461
4.

Progressive Intramuscular Haematoma in a 12-Year-Old Boy: A Case of Acquired Haemophilia A.

Gamage M, Weerasinghe S, Nasoor M, Karunarathne AMPW, Abeyrathne SP.

Case Rep Hematol. 2018 Oct 24;2018:6208597. doi: 10.1155/2018/6208597. eCollection 2018.

5.

Confocal Imaging and k-Means Clustering of GABAB and mGluR Mediated Modulation of Ca2+ Spiking in Hippocampal Neurons.

Swain S, Gupta RK, Ratnayake K, Priyanka PD, Singh R, Jana S, Mitra K, Karunarathne A, Giri L.

ACS Chem Neurosci. 2018 Dec 19;9(12):3094-3107. doi: 10.1021/acschemneuro.8b00297. Epub 2018 Aug 13.

PMID:
30044088
6.

Blue light excited retinal intercepts cellular signaling.

Ratnayake K, Payton JL, Lakmal OH, Karunarathne A.

Sci Rep. 2018 Jul 5;8(1):10207. doi: 10.1038/s41598-018-28254-8.

7.

G protein γ (Gγ) subtype dependent targeting of GRK2 to M3 receptor by Gβγ.

Samaradivakara S, Kankanamge D, Senarath K, Ratnayake K, Karunarathne A.

Biochem Biophys Res Commun. 2018 Sep 3;503(1):165-170. doi: 10.1016/j.bbrc.2018.05.204. Epub 2018 Jun 11.

PMID:
29864421
8.

Regulation of G Protein βγ Signaling.

Senarath K, Kankanamge D, Samaradivakara S, Ratnayake K, Tennakoon M, Karunarathne A.

Int Rev Cell Mol Biol. 2018;339:133-191. doi: 10.1016/bs.ircmb.2018.02.008. Epub 2018 Mar 28. Review.

PMID:
29776603
9.

Melanopsin (Opn4) utilizes Gαi and Gβγ as major signal transducers.

Kankanamge D, Ratnayake K, Samaradivakara S, Karunarathne A.

J Cell Sci. 2018 Jun 5;131(11). pii: jcs212910. doi: 10.1242/jcs.212910.

10.

Gγ identity dictates efficacy of Gβγ signaling and macrophage migration.

Senarath K, Payton JL, Kankanamge D, Siripurapu P, Tennakoon M, Karunarathne A.

J Biol Chem. 2018 Feb 23;293(8):2974-2989. doi: 10.1074/jbc.RA117.000872. Epub 2018 Jan 9.

11.

Measurement of GPCR-G protein activity in living cells.

Ratnayake K, Kankanamge D, Senarath K, Siripurapu P, Weis N, Tennakoon M, Payton JL, Karunarathne A.

Methods Cell Biol. 2017;142:1-25. doi: 10.1016/bs.mcb.2017.07.008. Epub 2017 Sep 19.

PMID:
28964328
12.

Two independent but synchronized Gβγ subunit-controlled pathways are essential for trailing-edge retraction during macrophage migration.

Siripurapu P, Kankanamge D, Ratnayake K, Senarath K, Karunarathne A.

J Biol Chem. 2017 Oct 20;292(42):17482-17495. doi: 10.1074/jbc.M117.787838. Epub 2017 Sep 1.

13.

Comparison of Calcium Dynamics and Specific Features for G Protein-Coupled Receptor-Targeting Drugs Using Live Cell Imaging and Automated Analysis.

Gupta RK, Swain S, Kankanamge D, Priyanka PD, Singh R, Mitra K, Karunarathne A, Giri L.

SLAS Discov. 2017 Aug;22(7):848-858. doi: 10.1177/2472555217693378. Epub 2017 Mar 7.

PMID:
28267930
14.

Reversible G Protein βγ9 Distribution-Based Assay Reveals Molecular Underpinnings in Subcellular, Single-Cell, and Multicellular GPCR and G Protein Activity.

Senarath K, Ratnayake K, Siripurapu P, Payton JL, Karunarathne A.

Anal Chem. 2016 Dec 6;88(23):11450-11459. Epub 2016 Nov 14.

PMID:
27778511

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