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Items: 1 to 50 of 70

1.

An integrated approach for mining precise RNA-based cervical cancer staging biomarkers.

Banerjee S, Karunagaran D.

Gene. 2019 Jul 4;712:143961. doi: 10.1016/j.gene.2019.143961. [Epub ahead of print]

PMID:
31279709
2.

Vitamin K3 (menadione) suppresses epithelial-mesenchymal-transition and Wnt signaling pathway in human colorectal cancer cells.

Kishore C, Sundaram S, Karunagaran D.

Chem Biol Interact. 2019 Jun 22;309:108725. doi: 10.1016/j.cbi.2019.108725. [Epub ahead of print]

PMID:
31238027
3.

A novel reporter system for cyclic AMP mediated gene expression in mammalian cells based on synthetic transgene expression system.

Durai L, Vijayalakshmi R, Karunagaran D.

Eur J Pharmacol. 2019 Jul 15;855:56-64. doi: 10.1016/j.ejphar.2019.04.037. Epub 2019 Apr 26.

PMID:
31034821
4.

Entrainment of superoxide rhythm by menadione in HCT116 colon cancer cells.

Kizhuveetil U, Palukuri MV, Sharma P, Karunagaran D, Rengaswamy R, Suraishkumar GK.

Sci Rep. 2019 Mar 4;9(1):3347. doi: 10.1038/s41598-019-40017-7.

5.

Antiproliferative and Apoptotic Activities of the Medicinal Mushroom Phellinus rimosus (Agaricomycetes) on HCT116 Human Colorectal Carcinoma Cells.

Meera CR, Janardhanan KK, Karunagaran D.

Int J Med Mushrooms. 2018;20(10):935-945. doi: 10.1615/IntJMedMushrooms.2018028343.

PMID:
30806266
6.

A Feedback Loop between MicroRNA 155 (miR-155), Programmed Cell Death 4, and Activation Protein 1 Modulates the Expression of miR-155 and Tumorigenesis in Tongue Cancer.

Zargar S, Tomar V, Shyamsundar V, Vijayalakshmi R, Somasundaram K, Karunagaran D.

Mol Cell Biol. 2019 Mar 1;39(6). pii: e00410-18. doi: 10.1128/MCB.00410-18. Print 2019 Mar 15.

PMID:
30617160
7.

Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-κ B and the serine/threonine kinase Akt and is independent of tubulin polymerization.

Bava SV, Puliyappadamba VT, Deepti A, Nair A, Karunagaran D, Anto RJ.

J Biol Chem. 2018 Aug 3;293(31):12283. doi: 10.1074/jbc.AAC118.004745. No abstract available.

8.

miR-214 activates TP53 but suppresses the expression of RELA, CTNNB1, and STAT3 in human cervical and colorectal cancer cells.

Chandrasekaran KS, Sathyanarayanan A, Karunagaran D.

Cell Biochem Funct. 2017 Oct;35(7):464-471. doi: 10.1002/cbf.3304. Epub 2017 Oct 10.

PMID:
29023799
9.

microRNA-145 downregulates SIP1-expression but differentially regulates proliferation, migration, invasion and Wnt signaling in SW480 and SW620 cells.

Sathyanarayanan A, Chandrasekaran KS, Karunagaran D.

J Cell Biochem. 2018 Feb;119(2):2022-2035. doi: 10.1002/jcb.26365. Epub 2017 Sep 18.

PMID:
28833449
10.

Reply: Comment on 'MicroRNA-214 suppresses growth, migration and invasion through a novel target, high mobility group AT-hook 1, in human cervical and colorectal cancer cells'.

Chandrasekaran KS, Sathyanarayanan A, Karunagaran D.

Br J Cancer. 2017 Jan;116(3):e8. doi: 10.1038/bjc.2016.410. Epub 2016 Dec 20. No abstract available.

11.

microRNA-145 modulates epithelial-mesenchymal transition and suppresses proliferation, migration and invasion by targeting SIP1 in human cervical cancer cells.

Sathyanarayanan A, Chandrasekaran KS, Karunagaran D.

Cell Oncol (Dordr). 2017 Apr;40(2):119-131. doi: 10.1007/s13402-016-0307-3. Epub 2016 Dec 8.

PMID:
27933466
12.

microRNA-146a inhibits proliferation, migration and invasion of human cervical and colorectal cancer cells.

Sathyanarayanan A, Chandrasekaran KS, Karunagaran D.

Biochem Biophys Res Commun. 2016 Nov 25;480(4):528-533. doi: 10.1016/j.bbrc.2016.10.054. Epub 2016 Oct 18.

PMID:
27769860
13.

MicroRNA-214 suppresses growth, migration and invasion through a novel target, high mobility group AT-hook 1, in human cervical and colorectal cancer cells.

Chandrasekaran KS, Sathyanarayanan A, Karunagaran D.

Br J Cancer. 2016 Sep 6;115(6):741-51. doi: 10.1038/bjc.2016.234. Epub 2016 Aug 18.

14.

Downregulation of HMGB1 by miR-34a is sufficient to suppress proliferation, migration and invasion of human cervical and colorectal cancer cells.

Chandrasekaran KS, Sathyanarayanan A, Karunagaran D.

Tumour Biol. 2016 Oct;37(10):13155-13166. Epub 2016 Jul 25.

PMID:
27456356
15.

Discrimination of driver and passenger mutations in epidermal growth factor receptor in cancer.

Anoosha P, Huang LT, Sakthivel R, Karunagaran D, Gromiha MM.

Mutat Res. 2015 Oct;780:24-34. doi: 10.1016/j.mrfmmm.2015.07.005. Epub 2015 Jul 20.

PMID:
26264175
16.

Curcumin and emodin down-regulate TGF-β signaling pathway in human cervical cancer cells.

Thacker PC, Karunagaran D.

PLoS One. 2015 Mar 18;10(3):e0120045. doi: 10.1371/journal.pone.0120045. eCollection 2015.

17.

Re-expression of HPV16 E2 in SiHa (human cervical cancer) cells potentiates NF-κB activation induced by TNF-α concurrently increasing senescence and survival.

Prabhavathy D, Subramanian CK, Karunagaran D.

Biosci Rep. 2015 Feb 25;35(1). pii: e00175. doi: 10.1042/BSR20140160.

18.

HPV16 E2 enhances the expression of NF-κB and STAT3 target genes and potentiates NF-κB activation by inflammatory mediators.

Prabhavathy D, Vijayalakshmi R, Kanchana MP, Karunagaran D.

Cell Immunol. 2014 Nov-Dec;292(1-2):70-7.

PMID:
25460081
19.

Emodin suppresses Wnt signaling in human colorectal cancer cells SW480 and SW620.

Pooja T, Karunagaran D.

Eur J Pharmacol. 2014 Nov 5;742:55-64. doi: 10.1016/j.ejphar.2014.08.028. Epub 2014 Sep 6.

PMID:
25205133
20.

Advances in chalcones with anticancer activities.

Karthikeyan C, Moorthy NS, Ramasamy S, Vanam U, Manivannan E, Karunagaran D, Trivedi P.

Recent Pat Anticancer Drug Discov. 2015;10(1):97-115. Review.

PMID:
25138130
21.

MiR-29b downregulates canonical Wnt signaling by suppressing coactivators of β-catenin in human colorectal cancer cells.

Subramanian M, Rao SR, Thacker P, Chatterjee S, Karunagaran D.

J Cell Biochem. 2014 Nov;115(11):1974-84. doi: 10.1002/jcb.24869.

PMID:
24913975
22.

Synthesis and SAR study of novel anticancer and antimicrobial naphthoquinone amide derivatives.

Sreelatha T, Kandhasamy S, Dinesh R, Shruthy S, Shweta S, Mukesh D, Karunagaran D, Balaji R, Mathivanan N, Perumal PT.

Bioorg Med Chem Lett. 2014 Aug 1;24(15):3647-51. doi: 10.1016/j.bmcl.2014.04.080. Epub 2014 May 20.

PMID:
24913712
23.

HPV16 E2-mediated potentiation of NF-κB activation induced by TNF-α involves parallel activation of STAT3 with a reduction in E2-induced apoptosis.

Prabhavathy D, Prabhakar BN, Karunagaran D.

Mol Cell Biochem. 2014 Sep;394(1-2):77-90. doi: 10.1007/s11010-014-2083-6. Epub 2014 May 16.

PMID:
24833467
24.

Plumbagin downregulates Wnt signaling independent of p53 in human colorectal cancer cells.

Raghu D, Karunagaran D.

J Nat Prod. 2014 May 23;77(5):1130-4. doi: 10.1021/np4010085. Epub 2014 May 14.

PMID:
24828199
25.

Proceedings of the Indo-U.S. bilateral workshop on accelerating botanicals/biologics agent development research for cancer chemoprevention, treatment, and survival.

Kumar NB, Dhurandhar M, Aggarwal B, Anant S, Daniel K, Deng G, Djeu J, Dou J, Hawk E, Jayaram B, Jia L, Joshi R, Kararala M, Karunagaran D, Kucuk O, Kumar L, Malafa M, Samathanam GJ, Sarkar F, Siddiqi M, Singh RP, Srivastava A, White JD.

Cancer Med. 2013 Feb;2(1):108-15.

27.

N-substituted 1,2-dihydroquinolines as anticancer agents: electronic control of redox stability, assessment of antiproliferative effects, and mechanistic insights.

John Victor N, Sakthivel R, Muraleedharan KM, Karunagaran D.

ChemMedChem. 2013 Oct;8(10):1623-8. doi: 10.1002/cmdc.201300210. Epub 2013 Aug 5.

PMID:
23918415
28.

MicroRNA-106b-25 cluster targets β-TRCP2, increases the expression of Snail and enhances cell migration and invasion in H1299 (non small cell lung cancer) cells.

Savita U, Karunagaran D.

Biochem Biophys Res Commun. 2013 May 17;434(4):841-7. doi: 10.1016/j.bbrc.2013.04.025. Epub 2013 Apr 20.

PMID:
23611780
29.

4-Amino-2-arylamino-5-indoloyl/cinnamoythiazoles, analogs of topsentin-class of marine alkaloids, induce apoptosis in HeLa cells.

Juneja M, Vanam U, Paranthaman S, Bharathan A, Keerthi VS, Reena JK, Rajaram R, Rajasekharan KN, Karunagaran D.

Eur J Med Chem. 2013 May;63:474-83. doi: 10.1016/j.ejmech.2013.02.032. Epub 2013 Mar 1.

PMID:
23524113
30.

Nimbolide, a neem limonoid abrogates canonical NF-κB and Wnt signaling to induce caspase-dependent apoptosis in human hepatocarcinoma (HepG2) cells.

Kavitha K, Vidya Priyadarsini R, Anitha P, Ramalingam K, Sakthivel R, Purushothaman G, Singh AK, Karunagaran D, Nagini S.

Eur J Pharmacol. 2012 Apr 15;681(1-3):6-14. doi: 10.1016/j.ejphar.2012.01.024. Epub 2012 Jan 31.

PMID:
22327045
31.

Chlorophyll revisited: anti-inflammatory activities of chlorophyll a and inhibition of expression of TNF-α gene by the same.

Subramoniam A, Asha VV, Nair SA, Sasidharan SP, Sureshkumar PK, Rajendran KN, Karunagaran D, Ramalingam K.

Inflammation. 2012 Jun;35(3):959-66. doi: 10.1007/s10753-011-9399-0.

PMID:
22038065
32.

The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition.

Vidya Priyadarsini R, Senthil Murugan R, Maitreyi S, Ramalingam K, Karunagaran D, Nagini S.

Eur J Pharmacol. 2010 Dec 15;649(1-3):84-91. doi: 10.1016/j.ejphar.2010.09.020. Epub 2010 Sep 19.

PMID:
20858478
33.

Intrinsic apoptosis and NF-κB signaling are potential molecular targets for chemoprevention by black tea polyphenols in HepG2 cells in vitro and in a rat hepatocarcinogenesis model in vivo.

Murugan RS, Priyadarsini RV, Ramalingam K, Hara Y, Karunagaran D, Nagini S.

Food Chem Toxicol. 2010 Nov;48(11):3281-7. doi: 10.1016/j.fct.2010.09.002. Epub 2010 Sep 7.

PMID:
20828598
34.

Quercetin attenuates Monocyte Chemoattractant Protein-1 gene expression in glucose primed aortic endothelial cells through NF-kappaB and AP-1.

Panicker SR, Sreenivas P, Babu MS, Karunagaran D, Kartha CC.

Pharmacol Res. 2010 Oct;62(4):328-36. doi: 10.1016/j.phrs.2010.06.003. Epub 2010 Jun 11.

PMID:
20542118
35.

The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells.

Priyadarsini RV, Murugan RS, Sripriya P, Karunagaran D, Nagini S.

Free Radic Res. 2010 Jun;44(6):624-34. doi: 10.3109/10715761003692503.

PMID:
20429769
36.

Changes in expression, and/or mutations in TGF-beta receptors (TGF-beta RI and TGF-beta RII) and Smad 4 in human ovarian tumors.

Antony ML, Nair R, Sebastian P, Karunagaran D.

J Cancer Res Clin Oncol. 2010 Mar;136(3):351-61. doi: 10.1007/s00432-009-0703-4.

PMID:
19916025
37.
38.

Biophysical evaluation of two red-shifted hypocrellin B derivatives as novel PDT agents.

Paul BT, Babu MS, Santhoshkumar TR, Karunagaran D, Selvam GS, Brown K, Woo T, Sharma S, Naicker S, Murugesan R.

J Photochem Photobiol B. 2009 Jan 9;94(1):38-44. doi: 10.1016/j.jphotobiol.2008.09.007. Epub 2008 Sep 30.

PMID:
18977666
39.

Anti-inflammatory effect of curcumin involves downregulation of MMP-9 in blood mononuclear cells.

Saja K, Babu MS, Karunagaran D, Sudhakaran PR.

Int Immunopharmacol. 2007 Dec 15;7(13):1659-67. Epub 2007 Sep 14.

PMID:
17996675
40.

Cell growth regulation.

Karunagaran D, Joseph J, Kumar TR.

Adv Exp Med Biol. 2007;595:245-68. Review.

PMID:
17569215
41.

Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells.

Erlich S, Tal-Or P, Liebling R, Blum R, Karunagaran D, Kloog Y, Pinkas-Kramarski R.

Biochem Pharmacol. 2006 Aug 14;72(4):427-36. Epub 2006 May 13.

PMID:
16780807
42.

Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol.

Mohan J, Gandhi AA, Bhavya BC, Rashmi R, Karunagaran D, Indu R, Santhoshkumar TR.

J Biol Chem. 2006 Jun 30;281(26):17599-611. Epub 2006 Apr 14.

43.

Of humans and canines: a comparative evaluation of heat shock and apoptosis-associated proteins in mammary tumors.

Kumaraguruparan R, Karunagaran D, Balachandran C, Manohar BM, Nagini S.

Clin Chim Acta. 2006 Mar;365(1-2):168-76. Epub 2005 Sep 19.

PMID:
16176813
44.

Biological and chemical inhibitors of NF-kappaB sensitize SiHa cells to cisplatin-induced apoptosis.

Venkatraman M, Anto RJ, Nair A, Varghese M, Karunagaran D.

Mol Carcinog. 2005 Sep;44(1):51-9.

PMID:
16044419
45.

Induction of apoptosis by curcumin and its implications for cancer therapy.

Karunagaran D, Rashmi R, Kumar TR.

Curr Cancer Drug Targets. 2005 Mar;5(2):117-29. Review.

PMID:
15810876
46.
47.
48.
49.

Differential activation of Smads in HeLa and SiHa cells that differ in their response to transforming growth factor-beta.

Maliekal TT, Anto RJ, Karunagaran D.

J Biol Chem. 2004 Aug 27;279(35):36287-92. Epub 2004 Jun 10.

50.

Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells.

Oommen S, Anto RJ, Srinivas G, Karunagaran D.

Eur J Pharmacol. 2004 Feb 6;485(1-3):97-103.

PMID:
14757128

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