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Items: 1 to 50 of 290

1.

A top priority in pre-eclampsia research: development of a reliable and inexpensive urinary screening test.

Scioscia M, Dekker GA, Chaouat G, Dawonauth L, Dechend R, Goldman-Wohl D, Gumilar E, Karumanchi SA, Kell DB, Rademacher TW, Robertson S, Saito S, Scherjon S, Staff AC, Vatish M, Robillard PY.

Lancet Glob Health. 2019 Oct;7(10):e1312-e1313. doi: 10.1016/S2214-109X(19)30319-5. No abstract available.

2.

A Step-Wedge in the Biochemical Diagnosis of Preeclampsia.

Lemoine ER, Karumanchi SA.

Clin Chem. 2019 Aug 6. pii: clinchem.2019.305920. doi: 10.1373/clinchem.2019.305920. [Epub ahead of print] No abstract available.

PMID:
31387886
3.

Oral regimen management of acute hypertension in pregnancy.

Lemoine ER, Karumanchi SA.

Lancet. 2019 Sep 21;394(10203):981-982. doi: 10.1016/S0140-6736(19)31717-9. Epub 2019 Aug 1. No abstract available.

4.

Risk of ischemic placental disease is increased following in vitro fertilization with oocyte donation: a retrospective cohort study.

Modest AM, Johnson KM, Karumanchi SA, Resetkova N, Young BC, Fox MP, Wise LA, Hacker MR.

J Assist Reprod Genet. 2019 Sep;36(9):1917-1926. doi: 10.1007/s10815-019-01545-3. Epub 2019 Jul 29.

PMID:
31359234
5.

Placental sFLT1 is associated with complement activation and syncytiotrophoblast damage in preeclampsia.

Yonekura Collier AR, Zsengeller Z, Pernicone E, Salahuddin S, Khankin EV, Karumanchi SA.

Hypertens Pregnancy. 2019 Aug;38(3):193-199. doi: 10.1080/10641955.2019.1640725. Epub 2019 Jul 10.

6.

Vitamin D-Binding Protein Deficiency and Homozygous Deletion of the GC Gene.

Berg AH, Karumanchi SA, Thadhani R.

N Engl J Med. 2019 Jun 27;380(26):2584-2585. doi: 10.1056/NEJMc1905282. No abstract available.

PMID:
31242375
7.

Author Correction: Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury.

Zhou HL, Zhang R, Anand P, Stomberski CT, Qian Z, Hausladen A, Wang L, Rhee EP, Parikh SM, Karumanchi SA, Stamler JS.

Nature. 2019 Jun;570(7759):E23. doi: 10.1038/s41586-019-1225-0.

PMID:
31089212
8.

Author Correction: Pre-eclampsia: pathogenesis, novel diagnostics and therapies.

Phipps EA, Thadhani R, Benzing T, Karumanchi SA.

Nat Rev Nephrol. 2019 Jun;15(6):386. doi: 10.1038/s41581-019-0156-1.

PMID:
31068691
9.

Solving Baroreceptor Mystery: Role of PIEZO Ion Channels.

Burke SD, Jordan J, Harrison DG, Karumanchi SA.

J Am Soc Nephrol. 2019 Jun;30(6):911-913. doi: 10.1681/ASN.2019020160. Epub 2019 May 1. No abstract available.

PMID:
31043433
10.

Failure in Physiologic Flexibility: Adverse Pregnancy Outcomes in Women with Reduced Renal Reserve.

Lemoine E, Karumanchi SA.

Am J Nephrol. 2019;49(5):397-399. doi: 10.1159/000499966. Epub 2019 Apr 12. No abstract available.

11.

Preeclampsia.

Rana S, Lemoine E, Granger J, Karumanchi SA.

Circ Res. 2019 Mar 29;124(7):1094-1112. doi: 10.1161/CIRCRESAHA.118.313276.

PMID:
30920918
12.

Pre-eclampsia: pathogenesis, novel diagnostics and therapies.

Phipps EA, Thadhani R, Benzing T, Karumanchi SA.

Nat Rev Nephrol. 2019 May;15(5):275-289. doi: 10.1038/s41581-019-0119-6. Review. Erratum in: Nat Rev Nephrol. 2019 Jun;15(6):386.

PMID:
30792480
13.

Research Recommendations From the National Institutes of Health Workshop on Predicting, Preventing, and Treating Preeclampsia.

Maric-Bilkan C, Abrahams VM, Arteaga SS, Bourjeily G, Conrad KP, Catov JM, Costantine MM, Cox B, Garovic V, George EM, Gernand AD, Jeyabalan A, Karumanchi SA, Laposky AD, Miodovnik M, Mitchell M, Pemberton VL, Reddy UM, Santillan MK, Tsigas E, Thornburg KLR, Ward K, Myatt L, Roberts JM.

Hypertension. 2019 Apr;73(4):757-766. doi: 10.1161/HYPERTENSIONAHA.118.11644. No abstract available.

PMID:
30686084
14.

Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury.

Zhou HL, Zhang R, Anand P, Stomberski CT, Qian Z, Hausladen A, Wang L, Rhee EP, Parikh SM, Karumanchi SA, Stamler JS.

Nature. 2019 Jan;565(7737):96-100. doi: 10.1038/s41586-018-0749-z. Epub 2018 Nov 28. Erratum in: Nature. 2019 Jun;570(7759):E23.

15.

RNAi modulation of placental sFLT1 for the treatment of preeclampsia.

Turanov AA, Lo A, Hassler MR, Makris A, Ashar-Patel A, Alterman JF, Coles AH, Haraszti RA, Roux L, Godinho BMDC, Echeverria D, Pears S, Iliopoulos J, Shanmugalingam R, Ogle R, Zsengeller ZK, Hennessy A, Karumanchi SA, Moore MJ, Khvorova A.

Nat Biotechnol. 2018 Nov 19. doi: 10.1038/nbt.4297. [Epub ahead of print]

16.

AP39, a Modulator of Mitochondrial Bioenergetics, Reduces Antiangiogenic Response and Oxidative Stress in Hypoxia-Exposed Trophoblasts: Relevance for Preeclampsia Pathogenesis.

Covarrubias AE, Lecarpentier E, Lo A, Salahuddin S, Gray KJ, Karumanchi SA, Zsengellér ZK.

Am J Pathol. 2019 Jan;189(1):104-114. doi: 10.1016/j.ajpath.2018.09.007. Epub 2018 Oct 11.

PMID:
30315766
17.

Complement 7 Is Up-Regulated in Human Early Diabetic Kidney Disease.

Sircar M, Rosales IA, Selig MK, Xu D, Zsengeller ZK, Stillman IE, Libermann TA, Karumanchi SA, Thadhani RI.

Am J Pathol. 2018 Oct;188(10):2147-2154. doi: 10.1016/j.ajpath.2018.06.018.

18.

Updates on Screening, Prevention, Treatment, and Genetic Markers for Preeclampsia.

Palomaki GE, Martin JN Jr, Karumanchi SA, Poon LC.

Clin Chem. 2018 Dec;64(12):1684-1689. doi: 10.1373/clinchem.2018.289801. Epub 2018 Sep 10. No abstract available.

PMID:
30201802
19.

Angiogenic biomarkers in triage and risk for preeclampsia with severe features.

Rana S, Salahuddin S, Mueller A, Berg AH, Thadhani RI, Karumanchi SA.

Pregnancy Hypertens. 2018 Jul;13:100-106. doi: 10.1016/j.preghy.2018.05.008. Epub 2018 May 25.

PMID:
30177034
20.

Serum Angiopoietin-2 Predicts Mortality and Kidney Outcomes in Decompensated Cirrhosis.

Allegretti AS, Vela Parada X, Ortiz GA, Long J, Krinsky S, Zhao S, Fuchs BC, Sojoodi M, Zhang D, Karumanchi SA, Kalim S, Nigwekar SU, Thadhani RI, Parikh SM, Chung RT.

Hepatology. 2019 Feb;69(2):729-741. doi: 10.1002/hep.30230. Epub 2019 Jan 4.

PMID:
30141205
21.

Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFβ1 Axis.

Prete A, Lo AS, Sadow PM, Bhasin SS, Antonello ZA, Vodopivec DM, Ullas S, Sims JN, Clohessy J, Dvorak AM, Sciuto T, Bhasin M, Murphy-Ullrich JE, Lawler J, Karumanchi SA, Nucera C.

Clin Cancer Res. 2018 Dec 1;24(23):6078-6097. doi: 10.1158/1078-0432.CCR-18-0693. Epub 2018 Aug 3.

PMID:
30076136
22.

Gene-Centric Analysis of Preeclampsia Identifies Maternal Association at PLEKHG1.

Gray KJ, Kovacheva VP, Mirzakhani H, Bjonnes AC, Almoguera B, DeWan AT, Triche EW, Saftlas AF, Hoh J, Bodian DL, Klein E, Huddleston KC, Ingles SA, Lockwood CJ, Hakonarson H, McElrath TF, Murray JC, Wilson ML, Norwitz ER, Karumanchi SA, Bateman BT, Keating BJ, Saxena R.

Hypertension. 2018 Aug;72(2):408-416. doi: 10.1161/HYPERTENSIONAHA.117.10688. Epub 2018 Jul 2.

23.

Risk of Preeclampsia and Pregnancy Complications in Women With a History of Acute Kidney Injury.

Tangren JS, Wan Md Adnan WAH, Powe CE, Ecker J, Bramham K, Hladunewich MA, Ankers E, Karumanchi SA, Thadhani R.

Hypertension. 2018 Aug;72(2):451-459. doi: 10.1161/HYPERTENSIONAHA.118.11161. Epub 2018 Jun 18.

24.

Hypertensive Disorders of Pregnancy: ISSHP Classification, Diagnosis, and Management Recommendations for International Practice.

Brown MA, Magee LA, Kenny LC, Karumanchi SA, McCarthy FP, Saito S, Hall DR, Warren CE, Adoyi G, Ishaku S; International Society for the Study of Hypertension in Pregnancy (ISSHP).

Hypertension. 2018 Jul;72(1):24-43. doi: 10.1161/HYPERTENSIONAHA.117.10803. Review. No abstract available.

PMID:
29899139
25.

Cerebrospinal Fluid Protein Changes in Preeclampsia.

Ciampa E, Li Y, Dillon S, Lecarpentier E, Sorabella L, Libermann TA, Karumanchi SA, Hess PE.

Hypertension. 2018 Jul;72(1):219-226. doi: 10.1161/HYPERTENSIONAHA.118.11153. Epub 2018 May 29.

PMID:
29844151
26.

The hypertensive disorders of pregnancy: ISSHP classification, diagnosis & management recommendations for international practice.

Brown MA, Magee LA, Kenny LC, Karumanchi SA, McCarthy FP, Saito S, Hall DR, Warren CE, Adoyi G, Ishaku S; International Society for the Study of Hypertension in Pregnancy (ISSHP).

Pregnancy Hypertens. 2018 Jul;13:291-310. doi: 10.1016/j.preghy.2018.05.004. Epub 2018 May 24. Review. No abstract available.

PMID:
29803330
27.

In Reply.

Lecarpentier E, Karumanchi SA, Haddad B.

Obstet Gynecol. 2018 May;131(5):936. doi: 10.1097/AOG.0000000000002606. No abstract available.

PMID:
29683899
28.

Angiogenic factors in pre-eclampsia: implications for clinical practice.

Karumanchi SA.

BJOG. 2018 Oct;125(11):1396. doi: 10.1111/1471-0528.15180. Epub 2018 Apr 11. No abstract available.

29.

Metabolic and Hypertensive Complications of Pregnancy in Women with Nephrolithiasis.

Tangren JS, Powe CE, Ecker J, Bramham K, Ankers E, Karumanchi SA, Thadhani R.

Clin J Am Soc Nephrol. 2018 Apr 6;13(4):612-619. doi: 10.2215/CJN.12171017. Epub 2018 Feb 22.

30.

Smooth Muscle Cell-Mineralocorticoid Receptor as a Mediator of Cardiovascular Stiffness With Aging.

Kim SK, McCurley AT, DuPont JJ, Aronovitz M, Moss ME, Stillman IE, Karumanchi SA, Christou DD, Jaffe IZ.

Hypertension. 2018 Apr;71(4):609-621. doi: 10.1161/HYPERTENSIONAHA.117.10437. Epub 2018 Feb 20.

31.

Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo.

Hassler MR, Turanov AA, Alterman JF, Haraszti RA, Coles AH, Osborn MF, Echeverria D, Nikan M, Salomon WE, Roux L, Godinho BMDC, Davis SM, Morrissey DV, Zamore PD, Karumanchi SA, Moore MJ, Aronin N, Khvorova A.

Nucleic Acids Res. 2018 Mar 16;46(5):2185-2196. doi: 10.1093/nar/gky037.

32.

Hepatic dysfunction and thrombocytopenia induced by excess sFlt1 in mice lacking endothelial nitric oxide synthase.

Oe Y, Ko M, Fushima T, Sato E, Karumanchi SA, Sato H, Sugawara J, Ito S, Takahashi N.

Sci Rep. 2018 Jan 8;8(1):102. doi: 10.1038/s41598-017-18260-7.

33.

Acute Homeostatic Changes Following Vitamin D2 Supplementation.

Berg AH, Bhan I, Powe C, Karumanchi SA, Xu D, Thadhani RI.

J Endocr Soc. 2017 Jul 19;1(9):1135-1149. doi: 10.1210/js.2017-00244. eCollection 2017 Sep 1.

34.

Angiogenic Factor Profiles in Pregnant Women With a History of Early-Onset Severe Preeclampsia Receiving Low-Molecular-Weight Heparin Prophylaxis.

Lecarpentier E, Gris JC, Cochery-Nouvellon E, Mercier E, Touboul C, Thadhani R, Karumanchi SA, Haddad B.

Obstet Gynecol. 2018 Jan;131(1):63-69. doi: 10.1097/AOG.0000000000002380.

PMID:
29215518
35.

Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAFV600E.

Antonello ZA, Hsu N, Bhasin M, Roti G, Joshi M, Van Hummelen P, Ye E, Lo AS, Karumanchi SA, Bryke CR, Nucera C.

Oncotarget. 2017 Sep 24;8(49):84743-84760. doi: 10.18632/oncotarget.21262. eCollection 2017 Oct 17.

36.

Genetic predisposition to preeclampsia is conferred by fetal DNA variants near FLT1, a gene involved in the regulation of angiogenesis.

Gray KJ, Saxena R, Karumanchi SA.

Am J Obstet Gynecol. 2018 Feb;218(2):211-218. doi: 10.1016/j.ajog.2017.11.562. Epub 2017 Nov 11. Review.

37.

FLT1 and transcriptome-wide polyadenylation site (PAS) analysis in preeclampsia.

Ashar-Patel A, Kaymaz Y, Rajakumar A, Bailey JA, Karumanchi SA, Moore MJ.

Sci Rep. 2017 Sep 22;7(1):12139. doi: 10.1038/s41598-017-11639-6.

38.

Soluble Fms-Like Tyrosine Kinase 1 (sFlt-1) and Risk of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage.

Griessenauer CJ, Chua MH, Hanafy KA, Baffour YT, Chen R, LeBlanc RH 3rd, Patel AS, Salem M, Karumanchi SA, Xu D, Thadhani R, Ogilvy CS, Thomas AJ.

World Neurosurg. 2017 Dec;108:84-89. doi: 10.1016/j.wneu.2017.08.128. Epub 2017 Sep 1.

PMID:
28867315
39.

Identification of Novel Non-secosteroidal Vitamin D Receptor Agonists with Potent Cardioprotective Effects and devoid of Hypercalcemia.

Khedkar SA, Samad MA, Choudhury S, Lee JY, Zhang D, Thadhani RI, Karumanchi SA, Rigby AC, Kang PM.

Sci Rep. 2017 Aug 16;7(1):8427. doi: 10.1038/s41598-017-08670-y.

40.

Preeclampsia: Pathogenesis, Prevention, and Long-Term Complications.

Jim B, Karumanchi SA.

Semin Nephrol. 2017 Jul;37(4):386-397. doi: 10.1016/j.semnephrol.2017.05.011. Review.

PMID:
28711078
41.

The pathology of eclampsia: An autopsy series.

Hecht JL, Ordi J, Carrilho C, Ismail MR, Zsengeller ZK, Karumanchi SA, Rosen S.

Hypertens Pregnancy. 2017 Aug;36(3):259-268. doi: 10.1080/10641955.2017.1329430. Epub 2017 Jul 5.

PMID:
28678644
42.

Down-regulation of soluble fms-like tyrosine kinase 1 expression in invasive placentation.

Shainker SA, Dannheim K, Gerson KD, Neo D, Zsengeller ZK, Pernicone E, Karumanchi SA, Hacker MR, Hecht JL.

Arch Gynecol Obstet. 2017 Aug;296(2):257-262. doi: 10.1007/s00404-017-4432-7. Epub 2017 Jun 19.

PMID:
28631072
43.

Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes.

Nezu M, Souma T, Yu L, Sekine H, Takahashi N, Wei AZ, Ito S, Fukamizu A, Zsengeller ZK, Nakamura T, Hozawa A, Karumanchi SA, Suzuki N, Yamamoto M.

Sci Signal. 2017 May 16;10(479). pii: eaam5711. doi: 10.1126/scisignal.aam5711.

PMID:
28512147
44.

Placental soluble fms-like tyrosine kinase expression in small for gestational age infants and risk for adverse outcomes.

Spiel M, Salahuddin S, Pernicone E, Zsengeller Z, Wang A, Modest AM, Karumanchi SA, Hecht JL.

Placenta. 2017 Apr;52:10-16. doi: 10.1016/j.placenta.2017.02.011. Epub 2017 Feb 10.

PMID:
28454690
45.

Offspring Cardiovascular Disease in Preeclampsia: Nature Versus Nurture?

Wang AM, Karumanchi SA.

Hypertension. 2017 Apr;69(4):589-590. doi: 10.1161/HYPERTENSIONAHA.117.08957. Epub 2017 Feb 21. No abstract available.

PMID:
28223476
46.

Relationship between hypoxia and downstream pathogenic pathways in preeclampsia.

Korkes HA, De Oliveira L, Sass N, Salahuddin S, Karumanchi SA, Rajakumar A.

Hypertens Pregnancy. 2017 May;36(2):145-150. doi: 10.1080/10641955.2016.1259627. Epub 2017 Jan 9.

PMID:
28067578
47.

Pregnancy Outcomes after Clinical Recovery from AKI.

Tangren JS, Powe CE, Ankers E, Ecker J, Bramham K, Hladunewich MA, Karumanchi SA, Thadhani R.

J Am Soc Nephrol. 2017 May;28(5):1566-1574. doi: 10.1681/ASN.2016070806. Epub 2016 Dec 22.

48.

PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model.

Erpenbeck L, Chowdhury CS, Zsengellér ZK, Gallant M, Burke SD, Cifuni S, Hahn S, Wagner DD, Karumanchi SA.

Biol Reprod. 2016 Dec;95(6):132. doi: 10.1095/biolreprod.116.140293. Epub 2016 Nov 9.

49.

Gelsolin is an endogenous inhibitor of syncytiotrophoblast extracellular vesicle shedding in pregnancy.

Nadkarni NA, Rajakumar A, Mokhashi N, Burke SD, Rana S, Salahuddin S, Dang Q, Thadhani R, Krishnan R, Stossel TP, Karumanchi SA.

Pregnancy Hypertens. 2016 Oct;6(4):333-339. doi: 10.1016/j.preghy.2016.07.003. Epub 2016 Jul 11.

PMID:
27939478
50.

A protocol for developing, disseminating, and implementing a core outcome set for pre-eclampsia.

Duffy JM, van 't Hooft J, Gale C, Brown M, Grobman W, Fitzpatrick R, Karumanchi SA, Lucas N, Magee L, Mol B, Stark M, Thangaratinam S, Wilson M, von Dadelszen P, Williamson P, Khan KS, Ziebland S, McManus RJ; International Collaboration to Harmonise Outcomes for Pre-eclampsia (iHOPE).

Pregnancy Hypertens. 2016 Oct;6(4):274-278. doi: 10.1016/j.preghy.2016.04.008. Epub 2016 May 4.

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