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Items: 10

1.

Colonic CD90+ Crypt Fibroblasts Secrete Semaphorins to Support Epithelial Growth.

Karpus ON, Westendorp BF, Vermeulen JLM, Meisner S, Koster J, Muncan V, Wildenberg ME, van den Brink GR.

Cell Rep. 2019 Mar 26;26(13):3698-3708.e5. doi: 10.1016/j.celrep.2019.02.101.

2.

Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response.

Westendorp BF, Büller NVJA, Karpus ON, van Dop WA, Koster J, Versteeg R, Koelink PJ, Snel CY, Meisner S, Roelofs JJTH, Uhmann A, Ver Loren van Themaat E, Heijmans J, Hahn H, Muncan V, Wildenberg ME, van den Brink GR.

Cell Mol Gastroenterol Hepatol. 2017 Sep 5;5(1):67-82.e1. doi: 10.1016/j.jcmgh.2017.08.004. eCollection 2018.

3.

Stromal cell markers are differentially expressed in the synovial tissue of patients with early arthritis.

Choi IY, Karpus ON, Turner JD, Hardie D, Marshall JL, de Hair MJH, Maijer KI, Tak PP, Raza K, Hamann J, Buckley CD, Gerlag DM, Filer A.

PLoS One. 2017 Aug 9;12(8):e0182751. doi: 10.1371/journal.pone.0182751. eCollection 2017.

4.

Intracellular delivery of poly(I:C) induces apoptosis of fibroblast-like synoviocytes via an unknown dsRNA sensor.

Karpus ON, Hsiao CC, de Kort H, Tak PP, Hamann J.

Biochem Biophys Res Commun. 2016 Aug 26;477(3):343-9. doi: 10.1016/j.bbrc.2016.06.104. Epub 2016 Jun 22.

PMID:
27343555
5.

CD55 deposited on synovial collagen fibers protects from immune complex-mediated arthritis.

Karpus ON, Kiener HP, Niederreiter B, Yilmaz-Elis AS, van der Kaa J, Ramaglia V, Arens R, Smolen JS, Botto M, Tak PP, Verbeek JS, Hamann J.

Arthritis Res Ther. 2015 Jan 17;17:6. doi: 10.1186/s13075-015-0518-4.

6.

Absence of Fms-like tyrosine kinase 3 ligand (Flt3L) signalling protects against collagen-induced arthritis.

Ramos MI, Karpus ON, Broekstra P, Aarrass S, Jacobsen SE, Tak PP, Lebre MC.

Ann Rheum Dis. 2015 Jan;74(1):211-9. doi: 10.1136/annrheumdis-2013-203371. Epub 2013 Sep 24.

PMID:
24064002
7.

Mice overexpressing CD97 in intestinal epithelial cells provide a unique model for mammalian postnatal intestinal cylindrical growth.

Aust G, Kerner C, Gonsior S, Sittig D, Schneider H, Buske P, Scholz M, Dietrich N, Oldenburg S, Karpus ON, Galle J, Amasheh S, Hamann J.

Mol Biol Cell. 2013 Jul;24(14):2256-68. doi: 10.1091/mbc.E13-04-0175. Epub 2013 May 15.

8.

Shear stress-dependent downregulation of the adhesion-G protein-coupled receptor CD97 on circulating leukocytes upon contact with its ligand CD55.

Karpus ON, Veninga H, Hoek RM, Flierman D, van Buul JD, Vandenakker CC, vanBavel E, Medof ME, van Lier RA, Reedquist KA, Hamann J.

J Immunol. 2013 Apr 1;190(7):3740-8. doi: 10.4049/jimmunol.1202192. Epub 2013 Feb 27.

9.

Triggering of the dsRNA sensors TLR3, MDA5, and RIG-I induces CD55 expression in synovial fibroblasts.

Karpus ON, Heutinck KM, Wijnker PJ, Tak PP, Hamann J.

PLoS One. 2012;7(5):e35606. doi: 10.1371/journal.pone.0035606. Epub 2012 May 10.

10.

Silencing the expression of Ras family GTPase homologues decreases inflammation and joint destruction in experimental arthritis.

de Launay D, Vreijling J, Hartkamp LM, Karpus ON, Abreu JR, van Maanen MA, Sanders ME, Grabiec AM, Hamann J, Ørum H, Vervoordeldonk MJ, Fluiter K, Tak PP, Reedquist KA.

Am J Pathol. 2010 Dec;177(6):3010-24. doi: 10.2353/ajpath.2010.091053. Epub 2010 Oct 22.

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