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Items: 19

1.

Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.

Bell CC, Fennell KA, Chan YC, Rambow F, Yeung MM, Vassiliadis D, Lara L, Yeh P, Martelotto LG, Rogiers A, Kremer BE, Barbash O, Mohammad HP, Johanson TM, Burr ML, Dhar A, Karpinich N, Tian L, Tyler DS, MacPherson L, Shi J, Pinnawala N, Yew Fong C, Papenfuss AT, Grimmond SM, Dawson SJ, Allan RS, Kruger RG, Vakoc CR, Goode DL, Naik SH, Gilan O, Lam EYN, Marine JC, Prinjha RK, Dawson MA.

Nat Commun. 2019 Jun 20;10(1):2723. doi: 10.1038/s41467-019-10652-9.

PMID:
31222014
2.

Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subtypes.

Smitheman KN, Severson TM, Rajapurkar SR, McCabe MT, Karpinich N, Foley J, Pappalardi MB, Hughes A, Halsey W, Thomas E, Traini C, Federowicz KE, Laraio J, Mobegi F, Ferron-Brady G, Prinjha RK, Carpenter CL, Kruger RG, Wessels L, Mohammad HP.

Haematologica. 2019 Jun;104(6):1156-1167. doi: 10.3324/haematol.2018.199190. Epub 2018 Dec 4.

3.

MEK inhibitors overcome resistance to BET inhibition across a number of solid and hematologic cancers.

Wyce A, Matteo JJ, Foley SW, Felitsky DJ, Rajapurkar SR, Zhang XP, Musso MC, Korenchuk S, Karpinich NO, Keenan KM, Stern M, Mathew LK, McHugh CF, McCabe MT, Tummino PJ, Kruger RG, Carpenter C, Barbash O.

Oncogenesis. 2018 Apr 20;7(4):35. doi: 10.1038/s41389-018-0043-9.

4.

Gap junction coupling is required for tumor cell migration through lymphatic endothelium.

Karpinich NO, Caron KM.

Arterioscler Thromb Vasc Biol. 2015 May;35(5):1147-55. doi: 10.1161/ATVBAHA.114.304752. Epub 2015 Mar 19.

5.

Decoy receptor CXCR7 modulates adrenomedullin-mediated cardiac and lymphatic vascular development.

Klein KR, Karpinich NO, Espenschied ST, Willcockson HH, Dunworth WP, Hoopes SL, Kushner EJ, Bautch VL, Caron KM.

Dev Cell. 2014 Sep 8;30(5):528-40. doi: 10.1016/j.devcel.2014.07.012.

6.

Schlemm's canal: more than meets the eye, lymphatics in disguise.

Karpinich NO, Caron KM.

J Clin Invest. 2014 Sep;124(9):3701-3. doi: 10.1172/JCI77507. Epub 2014 Jul 25.

7.

Midregional pro-adrenomedullin plasma concentrations are blunted in severe preeclampsia.

Matson BC, Corty RW, Karpinich NO, Murtha AP, Valdar W, Grotegut CA, Caron KM.

Placenta. 2014 Sep;35(9):780-3. doi: 10.1016/j.placenta.2014.07.003. Epub 2014 Jul 10.

8.

Apelin signaling: new G protein-coupled receptor pathway in lymphatic vascular development.

Karpinich NO, Caron KM.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):239-41. doi: 10.1161/ATVBAHA.113.302905. No abstract available.

9.

Cooperativity between MAPK and PI3K signaling activation is required for glioblastoma pathogenesis.

Vitucci M, Karpinich NO, Bash RE, Werneke AM, Schmid RS, White KK, McNeill RS, Huff B, Wang S, Van Dyke T, Miller CR.

Neuro Oncol. 2013 Oct;15(10):1317-29. doi: 10.1093/neuonc/not084. Epub 2013 Jun 27.

10.

Adrenomedullin gene dosage correlates with tumor and lymph node lymphangiogenesis.

Karpinich NO, Kechele DO, Espenschied ST, Willcockson HH, Fedoriw Y, Caron KM.

FASEB J. 2013 Feb;27(2):590-600. doi: 10.1096/fj.12-214080. Epub 2012 Oct 25.

11.

Adrenomedullin Function in Vascular Endothelial Cells: Insights from Genetic Mouse Models.

Karpinich NO, Hoopes SL, Kechele DO, Lenhart PM, Caron KM.

Curr Hypertens Rev. 2011 Dec;7(4):228-239.

12.

ERK-1 MAP kinase prevents TNF-induced apoptosis through bad phosphorylation and inhibition of Bax translocation in HeLa Cells.

Pucci B, Indelicato M, Paradisi V, Reali V, Pellegrini L, Aventaggiato M, Karpinich NO, Fini M, Russo MA, Farber JL, Tafani M.

J Cell Biochem. 2009 Dec 1;108(5):1166-74. doi: 10.1002/jcb.22345.

PMID:
19777442
13.

Detailing the role of Bax translocation, cytochrome c release, and perinuclear clustering of the mitochondria in the killing of HeLa cells by TNF.

Pucci B, Bertani F, Karpinich NO, Indelicato M, Russo MA, Farber JL, Tafani M.

J Cell Physiol. 2008 Nov;217(2):442-9. doi: 10.1002/jcp.21513.

PMID:
18546202
15.

The course of etoposide-induced apoptosis in Jurkat cells lacking p53 and Bax.

Karpinich NO, Tafani M, Schneider T, Russo MA, Farber JL.

J Cell Physiol. 2006 Jul;208(1):55-63.

PMID:
16547931
16.

Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha.

Tafani M, Cohn JA, Karpinich NO, Rothman RJ, Russo MA, Farber JL.

J Biol Chem. 2002 Dec 20;277(51):49569-76. Epub 2002 Oct 18.

17.

The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c.

Karpinich NO, Tafani M, Rothman RJ, Russo MA, Farber JL.

J Biol Chem. 2002 May 10;277(19):16547-52. Epub 2002 Feb 25.

18.

Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition.

Tafani M, Karpinich NO, Hurster KA, Pastorino JG, Schneider T, Russo MA, Farber JL.

J Biol Chem. 2002 Mar 22;277(12):10073-82. Epub 2002 Jan 14.

19.

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