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Items: 1 to 50 of 61

1.

ATG16 mediates the autophagic degradation of the 19S proteasomal subunits PSMD1 and PSMD2.

Xiong Q, Fischer S, Karow M, Müller R, Meßling S, Eichinger L.

Eur J Cell Biol. 2018 Nov;97(8):523-532. doi: 10.1016/j.ejcb.2018.09.002. Epub 2018 Sep 17.

2.

The regulatory subunit phr2AB of Dictyostelium discoideum phosphatase PP2A interacts with the centrosomal protein CEP161, a CDK5RAP2 ortholog.

Müller R, Stumpf M, Wehrstedt R, Sukumaran SK, Karow MA, Marko M, Noegel AA, Eichinger L.

Genes Cells. 2018 Oct;23(10):923-931. doi: 10.1111/gtc.12637. Epub 2018 Sep 21.

PMID:
30133996
3.

Expression of N471D strumpellin leads to defects in the endolysosomal system.

Song L, Rijal R, Karow M, Stumpf M, Hahn O, Park L, Insall R, Schröder R, Hofmann A, Clemen CS, Eichinger L.

Dis Model Mech. 2018 Sep 13;11(9). pii: dmm033449. doi: 10.1242/dmm.033449.

4.

Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program.

Karow M, Camp JG, Falk S, Gerber T, Pataskar A, Gac-Santel M, Kageyama J, Brazovskaja A, Garding A, Fan W, Riedemann T, Casamassa A, Smiyakin A, Schichor C, Götz M, Tiwari VK, Treutlein B, Berninger B.

Nat Neurosci. 2018 Jul;21(7):932-940. doi: 10.1038/s41593-018-0168-3. Epub 2018 Jun 18.

PMID:
29915193
5.

Technical Challenges and Opportunities when Implementing Pharmacogenomics Decision Support Integrated in the Electronic Health Record.

Caraballo PJ, Sutton JA, Moyer AM, Blair D, Hines LC, Rao PS, Adams MF, Murthy S, Garza T, Karow ME, Singh H, Giri J, Gabrielson DB, Sauver JS, Bielinski SJ, Parkulo MA.

Stud Health Technol Inform. 2017;245:1255.

PMID:
29295340
6.

Natural and forced neurogenesis: similar and yet different?

Falk S, Karow M.

Cell Tissue Res. 2018 Jan;371(1):181-187. doi: 10.1007/s00441-017-2690-0. Epub 2017 Sep 25. Review. No abstract available.

PMID:
28948355
7.

A tripeptidyl peptidase 1 is a binding partner of the Golgi pH regulator (GPHR) in Dictyostelium.

Stumpf M, Müller R, Gaßen B, Wehrstedt R, Fey P, Karow MA, Eichinger L, Glöckner G, Noegel AA.

Dis Model Mech. 2017 Jul 1;10(7):897-907. doi: 10.1242/dmm.029280. Epub 2017 May 25.

8.

Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming.

Gascón S, Murenu E, Masserdotti G, Ortega F, Russo GL, Petrik D, Deshpande A, Heinrich C, Karow M, Robertson SP, Schroeder T, Beckers J, Irmler M, Berndt C, Angeli JP, Conrad M, Berninger B, Götz M.

Cell Stem Cell. 2016 Mar 3;18(3):396-409. doi: 10.1016/j.stem.2015.12.003. Epub 2015 Dec 31.

9.

In-TOX-icating neurogenesis.

Karow M, Berninger B.

EMBO J. 2015 Apr 1;34(7):832-4. doi: 10.15252/embj.201591107. Epub 2015 Feb 17.

10.

Lineage-reprogramming of pericyte-derived cells of the adult human brain into induced neurons.

Karow M, Schichor C, Beckervordersandforth R, Berninger B.

J Vis Exp. 2014 May 12;(87). doi: 10.3791/51433.

11.

Recombinase-mediated reprogramming and dystrophin gene addition in mdx mouse induced pluripotent stem cells.

Zhao C, Farruggio AP, Bjornson CR, Chavez CL, Geisinger JM, Neal TL, Karow M, Calos MP.

PLoS One. 2014 Apr 29;9(4):e96279. doi: 10.1371/journal.pone.0096279. eCollection 2014.

12.

Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes.

Macdonald LE, Karow M, Stevens S, Auerbach W, Poueymirou WT, Yasenchak J, Frendewey D, Valenzuela DM, Giallourakis CC, Alt FW, Yancopoulos GD, Murphy AJ.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5147-52. doi: 10.1073/pnas.1323896111. Epub 2014 Mar 25.

13.

Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice.

Murphy AJ, Macdonald LE, Stevens S, Karow M, Dore AT, Pobursky K, Huang TT, Poueymirou WT, Esau L, Meola M, Mikulka W, Krueger P, Fairhurst J, Valenzuela DM, Papadopoulos N, Yancopoulos GD.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5153-8. doi: 10.1073/pnas.1324022111. Epub 2014 Mar 25.

14.

Mountaineering pericytes--a universal key to tissue repair?

Karow M.

Bioessays. 2013 Sep;35(9):771-4. doi: 10.1002/bies.201300055. Epub 2013 Jun 11.

PMID:
23757054
15.

Evolution and emergence of therapeutic monoclonal antibodies: what cardiologists need to know.

Foltz IN, Karow M, Wasserman SM.

Circulation. 2013 Jun 4;127(22):2222-30. doi: 10.1161/CIRCULATIONAHA.113.002033. Review. No abstract available.

PMID:
23733968
16.

Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex.

Foltz IN, Hu S, King C, Wu X, Yang C, Wang W, Weiszmann J, Stevens J, Chen JS, Nuanmanee N, Gupte J, Komorowski R, Sekirov L, Hager T, Arora T, Ge H, Baribault H, Wang F, Sheng J, Karow M, Wang M, Luo Y, McKeehan W, Wang Z, Véniant MM, Li Y.

Sci Transl Med. 2012 Nov 28;4(162):162ra153. doi: 10.1126/scitranslmed.3004690.

17.

Beam quality degradation of a single-frequency Yb-doped photonic crystal fiber amplifier with low mode instability threshold power.

Karow M, Tünnermann H, Neumann J, Kracht D, Wessels P.

Opt Lett. 2012 Oct 15;37(20):4242-4. doi: 10.1364/OL.37.004242.

PMID:
23073424
18.

Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells.

Karow M, Sánchez R, Schichor C, Masserdotti G, Ortega F, Heinrich C, Gascón S, Khan MA, Lie DC, Dellavalle A, Cossu G, Goldbrunner R, Götz M, Berninger B.

Cell Stem Cell. 2012 Oct 5;11(4):471-6. doi: 10.1016/j.stem.2012.07.007.

19.

Safe genetic modification of cardiac stem cells using a site-specific integration technique.

Lan F, Liu J, Narsinh KH, Hu S, Han L, Lee AS, Karow M, Nguyen PK, Nag D, Calos MP, Robbins RC, Wu JC.

Circulation. 2012 Sep 11;126(11 Suppl 1):S20-8.

20.

LRP6 mediates Wnt/β-catenin signaling and regulates adipogenic differentiation in human mesenchymal stem cells.

Peröbner I, Karow M, Jochum M, Neth P.

Int J Biochem Cell Biol. 2012 Nov;44(11):1970-82. doi: 10.1016/j.biocel.2012.07.025. Epub 2012 Aug 2.

PMID:
22871567
21.

Impact of amplified spontaneous emission on Brillouin scattering of a single-frequency signal.

Karow M, Neumann J, Kracht D, Weßels P.

Opt Express. 2012 May 7;20(10):10572-82. doi: 10.1364/OE.20.010572.

PMID:
22565683
22.

TEM 00 mode content of a two stage single-frequency Yb-doped PCF MOPA with 246 W of output power.

Karow M, Basu C, Kracht D, Neumann J, Wessels P.

Opt Express. 2012 Feb 27;20(5):5319-24. doi: 10.1364/OE.20.005319.

PMID:
22418338
23.

Mice completely lacking immunoproteasomes show major changes in antigen presentation.

Kincaid EZ, Che JW, York I, Escobar H, Reyes-Vargas E, Delgado JC, Welsh RM, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rock KL.

Nat Immunol. 2011 Dec 25;13(2):129-35. doi: 10.1038/ni.2203.

24.

Site-specific recombinase strategy to create induced pluripotent stem cells efficiently with plasmid DNA.

Karow M, Chavez CL, Farruggio AP, Geisinger JM, Keravala A, Jung WE, Lan F, Wu JC, Chen-Tsai Y, Calos MP.

Stem Cells. 2011 Nov;29(11):1696-704. doi: 10.1002/stem.730.

25.

Reporter gene HEK 293 cells and WNT/Frizzled fusion proteins as tools to study WNT signaling pathways.

Ring L, Peröbner I, Karow M, Jochum M, Neth P, Faussner A.

Biol Chem. 2011 Nov;392(11):1011-20. doi: 10.1515/BC.2011.164.

PMID:
21864196
26.

The effects of a plant proteinase inhibitor from Enterolobium contortisiliquum on human tumor cell lines.

Nakahata AM, Mayer B, Ries C, de Paula CA, Karow M, Neth P, Sampaio MU, Jochum M, Oliva ML.

Biol Chem. 2011 Apr;392(4):327-36. doi: 10.1515/BC.2011.031.

PMID:
21781023
27.

The therapeutic potential of ΦC31 integrase as a gene therapy system.

Karow M, Calos MP.

Expert Opin Biol Ther. 2011 Oct;11(10):1287-96. doi: 10.1517/14712598.2011.601293. Epub 2011 Jul 8. Review.

PMID:
21736536
28.

Interleukin-19 is a negative regulator of innate immunity and critical for colonic protection.

Azuma YT, Matsuo Y, Nakajima H, Yancopoulos GD, Valenzuela DM, Murphy AJ, Karow M, Takeuchi T.

J Pharmacol Sci. 2011;115(2):105-11. Epub 2010 Dec 9. Review.

29.

Virulence genes and genotypic associations in nasal carriage, community-associated methicillin-susceptible and methicillin-resistant USA400 Staphylococcus aureus isolates.

Shukla SK, Karow ME, Brady JM, Stemper ME, Kislow J, Moore N, Wroblewski K, Chyou PH, Warshauer DM, Reed KD, Lynfield R, Schwan WR.

J Clin Microbiol. 2010 Oct;48(10):3582-92. doi: 10.1128/JCM.00657-10. Epub 2010 Jul 28.

30.

Interleukin-19 protects mice from innate-mediated colonic inflammation.

Azuma YT, Matsuo Y, Kuwamura M, Yancopoulos GD, Valenzuela DM, Murphy AJ, Nakajima H, Karow M, Takeuchi T.

Inflamm Bowel Dis. 2010 Jun;16(6):1017-28. doi: 10.1002/ibd.21151.

PMID:
19834971
31.

Wnt signalling in mouse mesenchymal stem cells: impact on proliferation, invasion and MMP expression.

Karow M, Popp T, Egea V, Ries C, Jochum M, Neth P.

J Cell Mol Med. 2009 Aug;13(8B):2506-20. doi: 10.1111/j.1582-4934.2008.00619.x. Epub 2008 Dec 24.

32.

Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung.

Nair MG, Du Y, Perrigoue JG, Zaph C, Taylor JJ, Goldschmidt M, Swain GP, Yancopoulos GD, Valenzuela DM, Murphy A, Karow M, Stevens S, Pearce EJ, Artis D.

J Exp Med. 2009 Apr 13;206(4):937-52. doi: 10.1084/jem.20082048. Epub 2009 Apr 6. Erratum in: J Exp Med. 2009 May 11;206(5):1201.

33.

Human osteoblast-derived factors induce early osteogenic markers in human mesenchymal stem cells.

Ilmer M, Karow M, Geissler C, Jochum M, Neth P.

Tissue Eng Part A. 2009 Sep;15(9):2397-409. doi: 10.1089/ten.tea.2008.0427.

PMID:
19292682
34.

Goblet cell-derived resistin-like molecule beta augments CD4+ T cell production of IFN-gamma and infection-induced intestinal inflammation.

Nair MG, Guild KJ, Du Y, Zaph C, Yancopoulos GD, Valenzuela DM, Murphy A, Stevens S, Karow M, Artis D.

J Immunol. 2008 Oct 1;181(7):4709-15.

35.

Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections.

Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL.

J Immunol. 2008 Feb 1;180(3):1704-12.

36.

Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation.

Zenewicz LA, Yancopoulos GD, Valenzuela DM, Murphy AJ, Karow M, Flavell RA.

Immunity. 2007 Oct;27(4):647-59. Epub 2007 Oct 4.

37.

The Wnt signal transduction pathway in stem cells and cancer cells: influence on cellular invasion.

Neth P, Ries C, Karow M, Egea V, Ilmer M, Jochum M.

Stem Cell Rev. 2007 Jan;3(1):18-29. Review.

PMID:
17873378
38.

Resistin-like molecule-beta is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung.

Mishra A, Wang M, Schlotman J, Nikolaidis NM, DeBrosse CW, Karow ML, Rothenberg ME.

Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L305-13. Epub 2007 Jun 1.

39.
40.

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.

Haigis MC, Mostoslavsky R, Haigis KM, Fahie K, Christodoulou DC, Murphy AJ, Valenzuela DM, Yancopoulos GD, Karow M, Blander G, Wolberger C, Prolla TA, Weindruch R, Alt FW, Guarente L.

Cell. 2006 Sep 8;126(5):941-54.

41.

Cutting edge: IL-23 cross-regulates IL-12 production in T cell-dependent experimental colitis.

Becker C, Dornhoff H, Neufert C, Fantini MC, Wirtz S, Huebner S, Nikolaev A, Lehr HA, Murphy AJ, Valenzuela DM, Yancopoulos GD, Galle PR, Karow M, Neurath MF.

J Immunol. 2006 Sep 1;177(5):2760-4.

42.

Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility.

Hogan SP, Seidu L, Blanchard C, Groschwitz K, Mishra A, Karow ML, Ahrens R, Artis D, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rothenberg ME.

J Allergy Clin Immunol. 2006 Jul;118(1):257-68.

43.

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6.

Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mostoslavsky G, Franco S, Murphy MM, Mills KD, Patel P, Hsu JT, Hong AL, Ford E, Cheng HL, Kennedy C, Nunez N, Bronson R, Frendewey D, Auerbach W, Valenzuela D, Karow M, Hottiger MO, Hursting S, Barrett JC, Guarente L, Mulligan R, Demple B, Yancopoulos GD, Alt FW.

Cell. 2006 Jan 27;124(2):315-29.

44.

Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation.

Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL.

J Immunol. 2005 Nov 15;175(10):6605-14.

45.

The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia.

Pope SM, Zimmermann N, Stringer KF, Karow ML, Rothenberg ME.

J Immunol. 2005 Oct 15;175(8):5341-50.

46.

Recognition of single-stranded RNA viruses by Toll-like receptor 7.

Lund JM, Alexopoulou L, Sato A, Karow M, Adams NC, Gale NW, Iwasaki A, Flavell RA.

Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5598-603. Epub 2004 Mar 19.

47.

Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering.

Davis S, Papadopoulos N, Aldrich TH, Maisonpierre PC, Huang T, Kovac L, Xu A, Leidich R, Radziejewska E, Rafique A, Goldberg J, Jain V, Bailey K, Karow M, Fandl J, Samuelsson SJ, Ioffe E, Rudge JS, Daly TJ, Radziejewski C, Yancopoulos GD.

Nat Struct Biol. 2003 Jan;10(1):38-44. Erratum in: Nat Struct Biol. 2003 Feb;10(2):146.

PMID:
12469114
48.

Suppression of TGA mutations in the Bacillus subtilis spoIIR gene by prfB mutations.

Karow ML, Rogers EJ, Lovett PS, Piggot PJ.

J Bacteriol. 1998 Aug;180(16):4166-70.

49.

Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor.

Carpenter LR, Farruggella TJ, Symes A, Karow ML, Yancopoulos GD, Stahl N.

Proc Natl Acad Sci U S A. 1998 May 26;95(11):6061-6.

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