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Items: 34

1.

The effects of electronic cigarette vapour on the lung: direct comparison to tobacco smoke.

Reinikovaite V, Rodriguez IE, Karoor V, Rau A, Trinh BB, Deleyiannis FW, Taraseviciene-Stewart L.

Eur Respir J. 2018 Apr 4;51(4). pii: 1701661. doi: 10.1183/13993003.01661-2017. Print 2018 Apr. No abstract available.

PMID:
29449423
2.

Sustained Activation of Rho GTPases Promotes a Synthetic Pulmonary Artery Smooth Muscle Cell Phenotype in Neprilysin Null Mice.

Karoor V, Fini MA, Loomis Z, Sullivan T, Hersh LB, Gerasimovskaya E, Irwin D, Dempsey EC.

Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):154-163. doi: 10.1161/ATVBAHA.117.310207. Epub 2017 Nov 30.

PMID:
29191928
3.

Alcohol abuse is associated with enhanced pulmonary and systemic xanthine oxidoreductase activity.

Fini MA, Gaydos J, McNally A, Karoor V, Burnham EL.

Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1047-L1057. doi: 10.1152/ajplung.00570.2016. Epub 2017 Aug 24.

PMID:
28839105
4.

Correction: Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation.

Loomis Z, Eigenberger P, Redinius K, Lisk C, Karoor V, Nozik-Grayck E, Ferguson SK, Hassell K, Nuss R, Stenmark KR, Buehler PW, Irwin DC.

PLoS One. 2017 Mar 6;12(3):e0173652. doi: 10.1371/journal.pone.0173652. eCollection 2017.

5.

Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation.

Loomis Z, Eigenberger P, Redinius K, Lisk C, Karoor V, Nozik-Grayck E, Ferguson SK, Hassell K, Nuss R, Stenmark K, Buehler P, Irwin DC.

PLoS One. 2017 Feb 2;12(2):e0171219. doi: 10.1371/journal.pone.0171219. eCollection 2017. Erratum in: PLoS One. 2017 Mar 6;12 (3):e0173652.

6.

Glycolysis and oxidative phosphorylation are essential for purinergic receptor-mediated angiogenic responses in vasa vasorum endothelial cells.

Lapel M, Weston P, Strassheim D, Karoor V, Burns N, Lyubchenko T, Paucek P, Stenmark KR, Gerasimovskaya EV.

Am J Physiol Cell Physiol. 2017 Jan 1;312(1):C56-C70. doi: 10.1152/ajpcell.00250.2016. Epub 2016 Nov 16.

7.

Neprilysin regulates pulmonary artery smooth muscle cell phenotype through a platelet-derived growth factor receptor-dependent mechanism.

Karoor V, Oka M, Walchak SJ, Hersh LB, Miller YE, Dempsey EC.

Hypertension. 2013 Apr;61(4):921-30. doi: 10.1161/HYPERTENSIONAHA.111.199588. Epub 2013 Feb 4.

8.

Sleep-disordered breathing, hypoxemia, and cancer mortality.

Miller YE, Karoor V, Dempsey EC, Fagan KA.

Am J Respir Crit Care Med. 2013 Feb 1;187(3):330-1. No abstract available.

PMID:
23378442
9.

Alveolar hypoxia promotes murine lung tumor growth through a VEGFR-2/EGFR-dependent mechanism.

Karoor V, Le M, Merrick D, Fagan KA, Dempsey EC, Miller YE.

Cancer Prev Res (Phila). 2012 Aug;5(8):1061-71. doi: 10.1158/1940-6207.CAPR-12-0069-T. Epub 2012 Jun 14.

10.

Vascular endothelial growth factor receptor 2-targeted chemoprevention of murine lung tumors.

Karoor V, Le M, Merrick D, Dempsey EC, Miller YE.

Cancer Prev Res (Phila). 2010 Sep;3(9):1141-7. doi: 10.1158/1940-6207.CAPR-10-0005. Epub 2010 Jul 20.

11.

Chemoprevention of murine lung cancer by gefitinib in combination with prostacyclin synthase overexpression.

Keith RL, Karoor V, Mozer AB, Hudish TM, Le M, Miller YE.

Lung Cancer. 2010 Oct;70(1):37-42. doi: 10.1016/j.lungcan.2010.01.004. Epub 2010 Jan 29.

12.

Sustained hypoxia promotes the development of a pulmonary artery-specific chronic inflammatory microenvironment.

Burke DL, Frid MG, Kunrath CL, Karoor V, Anwar A, Wagner BD, Strassheim D, Stenmark KR.

Am J Physiol Lung Cell Mol Physiol. 2009 Aug;297(2):L238-50. doi: 10.1152/ajplung.90591.2008. Epub 2009 May 22.

13.

Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia.

Dempsey EC, Wick MJ, Karoor V, Barr EJ, Tallman DW, Wehling CA, Walchak SJ, Laudi S, Le M, Oka M, Majka S, Cool CD, Fagan KA, Klemm DJ, Hersh LB, Gerard NP, Gerard C, Miller YE.

Am J Pathol. 2009 Mar;174(3):782-96. doi: 10.2353/ajpath.2009.080345.

14.

Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosterone.

Homma N, Nagaoka T, Karoor V, Imamura M, Taraseviciene-Stewart L, Walker LA, Fagan KA, McMurtry IF, Oka M.

Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L71-8. doi: 10.1152/ajplung.90251.2008. Epub 2008 May 9.

15.

Endothelin-1 and serotonin are involved in activation of RhoA/Rho kinase signaling in the chronically hypoxic hypertensive rat pulmonary circulation.

Homma N, Nagaoka T, Morio Y, Ota H, Gebb SA, Karoor V, McMurtry IF, Oka M.

J Cardiovasc Pharmacol. 2007 Dec;50(6):697-702.

PMID:
18091588
16.

Dehydroepiandrosterone upregulates soluble guanylate cyclase and inhibits hypoxic pulmonary hypertension.

Oka M, Karoor V, Homma N, Nagaoka T, Sakao E, Golembeski SM, Limbird J, Imamura M, Gebb SA, Fagan KA, McMurtry IF.

Cardiovasc Res. 2007 Jun 1;74(3):377-87. Epub 2007 Feb 12.

17.

Role of rho in the increased migration of pulmonary artery smooth muscle cells observed in the neprilysin knockout mouse.

Karoor V, Walchak SJ, Miller YE, Dempsey EC.

Chest. 2005 Dec;128(6 Suppl):582S-583S. No abstract available.

PMID:
16373846
18.

Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat.

Nagaoka T, Gebb SA, Karoor V, Homma N, Morris KG, McMurtry IF, Oka M.

J Appl Physiol (1985). 2006 Mar;100(3):996-1002. Epub 2005 Dec 1.

19.

Agonist-dependent internalization of the angiotensin II type one receptor (AT1): role of C-terminus phosphorylation in recruitment of beta-arrestins.

Kule CE, Karoor V, Day JN, Thomas WG, Baker KM, Dinh D, Acker KA, Booz GW.

Regul Pept. 2004 Aug 15;120(1-3):141-8.

PMID:
15177932
20.

Propranolol prevents enhanced stress signaling in Gs alpha cardiomyopathy: potential mechanism for beta-blockade in heart failure.

Karoor V, Vatner SF, Takagi G, Yang G, Thaisz J, Sadoshima J, Vatner DE.

J Mol Cell Cardiol. 2004 Feb;36(2):305-12.

PMID:
14871558
21.

Neurally-mediated increase in calcineurin activity regulates cardiac contractile function in absence of hypertrophy.

Li J, Yatani A, Kim SJ, Takagi G, Irie K, Zhang Q, Karoor V, Hong C, Yang G, Sadoshima J, Depre C, Vatner DE, West MJ, Vatner SF.

Cardiovasc Res. 2003 Sep 1;59(3):649-57.

PMID:
14499866
22.

The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy.

Sadoshima J, Montagne O, Wang Q, Yang G, Warden J, Liu J, Takagi G, Karoor V, Hong C, Johnson GL, Vatner DE, Vatner SF.

J Clin Invest. 2002 Jul;110(2):271-9.

23.

Cyclosporine reduces left ventricular mass with chronic aortic banding in mice, which could be due to apoptosis and fibrosis.

Yang G, Meguro T, Hong C, Asai K, Takagi G, Karoor VL, Sadoshima J, Vatner DE, Bishop SP, Vatner SF.

J Mol Cell Cardiol. 2001 Aug;33(8):1505-14.

PMID:
11448138
24.

Cardiotrophin-1 increases angiotensinogen mRNA in rat cardiac myocytes through STAT3 : an autocrine loop for hypertrophy.

Fukuzawa J, Booz GW, Hunt RA, Shimizu N, Karoor V, Baker KM, Dostal DE.

Hypertension. 2000 Jun;35(6):1191-6.

PMID:
10856262
25.
26.

G-protein-linked receptors as tyrosine kinase substrates: new paradigms in signal integration.

Malbon CC, Karoor V.

Cell Signal. 1998 Sep;10(8):523-7. Review.

PMID:
9794250
27.

Phosphorylation of the angiotensin II (AT1A) receptor carboxyl terminus: a role in receptor endocytosis.

Thomas WG, Motel TJ, Kule CE, Karoor V, Baker KM.

Mol Endocrinol. 1998 Oct;12(10):1513-24.

PMID:
9773975
28.

Molecular mechanisms of angiotensin II in modulating cardiac function: intracardiac effects and signal transduction pathways.

Dostal DE, Hunt RA, Kule CE, Bhat GJ, Karoor V, McWhinney CD, Baker KM.

J Mol Cell Cardiol. 1997 Nov;29(11):2893-902. Review.

PMID:
9405164
29.

G-protein-linked receptors as substrates for tyrosine kinases: cross-talk in signaling.

Karoor V, Malbon CC.

Adv Pharmacol. 1998;42:425-8. No abstract available.

PMID:
9327930
31.

Regulating expression and function of G-protein-linked receptors.

Karoor V, Shih M, Tholanikunnel B, Malbon CC.

Prog Neurobiol. 1996 Apr;48(6):555-68. Review.

PMID:
8809908
32.

The beta-adrenergic receptor is a substrate for the insulin receptor tyrosine kinase.

Baltensperger K, Karoor V, Paul H, Ruoho A, Czech MP, Malbon CC.

J Biol Chem. 1996 Jan 12;271(2):1061-4.

33.

Phosphorylation of tyrosyl residues 350/354 of the beta-adrenergic receptor is obligatory for counterregulatory effects of insulin.

Karoor V, Baltensperger K, Paul H, Czech MP, Malbon CC.

J Biol Chem. 1995 Oct 27;270(43):25305-8.

34.

Utilization of selenocysteyl-tRNA[Ser]Sec and seryl-tRNA[Ser]Sec in protein synthesis.

Jung JE, Karoor V, Sandbaken MG, Lee BJ, Ohama T, Gesteland RF, Atkins JF, Mullenbach GT, Hill KE, Wahba AJ, et al.

J Biol Chem. 1994 Nov 25;269(47):29739-45.

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