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Items: 14


Reconstitution of immune cell populations in multiple sclerosis patients after autologous stem cell transplantation.

Karnell FG, Lin D, Motley S, Duhen T, Lim N, Campbell DJ, Turka LA, Maecker HT, Harris KM.

Clin Exp Immunol. 2017 Sep;189(3):268-278. doi: 10.1111/cei.12985. Epub 2017 Jun 7.


CD19 and CD32b differentially regulate human B cell responsiveness.

Karnell JL, Dimasi N, Karnell FG 3rd, Fleming R, Kuta E, Wilson M, Wu H, Gao C, Herbst R, Ettinger R.

J Immunol. 2014 Feb 15;192(4):1480-90. doi: 10.4049/jimmunol.1301361. Epub 2014 Jan 17.


Mycophenolic acid differentially impacts B cell function depending on the stage of differentiation.

Karnell JL, Karnell FG 3rd, Stephens GL, Rajan B, Morehouse C, Li Y, Swerdlow B, Wilson M, Goldbach-Mansky R, Groves C, Coyle AJ, Herbst R, Ettinger R.

J Immunol. 2011 Oct 1;187(7):3603-12. doi: 10.4049/jimmunol.1003319. Epub 2011 Aug 26.


Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling.

Stadanlick JE, Kaileh M, Karnell FG, Scholz JL, Miller JP, Quinn WJ 3rd, Brezski RJ, Treml LS, Jordan KA, Monroe JG, Sen R, Cancro MP.

Nat Immunol. 2008 Dec;9(12):1379-87. doi: 10.1038/ni.1666. Epub 2008 Nov 2.


Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies.

Zweidler-McKay PA, He Y, Xu L, Rodriguez CG, Karnell FG, Carpenter AC, Aster JC, Allman D, Pear WS.

Blood. 2005 Dec 1;106(12):3898-906. Epub 2005 Aug 23.


Membrane cholesterol content accounts for developmental differences in surface B cell receptor compartmentalization and signaling.

Karnell FG, Brezski RJ, King LB, Silverman MA, Monroe JG.

J Biol Chem. 2005 Jul 8;280(27):25621-8. Epub 2005 May 5.


The coiled-coil domain and Tyr177 of bcr are required to induce a murine chronic myelogenous leukemia-like disease by bcr/abl.

He Y, Wertheim JA, Xu L, Miller JP, Karnell FG, Choi JK, Ren R, Pear WS.

Blood. 2002 Apr 15;99(8):2957-68.


Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1.

Izon DJ, Aster JC, He Y, Weng A, Karnell FG, Patriub V, Xu L, Bakkour S, Rodriguez C, Allman D, Pear WS.

Immunity. 2002 Feb;16(2):231-43.


p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl).

Di Cristofano A, Niki M, Zhao M, Karnell FG, Clarkson B, Pear WS, Van Aelst L, Pandolfi PP.

J Exp Med. 2001 Aug 6;194(3):275-84.


Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells.

Allman D, Karnell FG, Punt JA, Bakkour S, Xu L, Myung P, Koretzky GA, Pui JC, Aster JC, Pear WS.

J Exp Med. 2001 Jul 2;194(1):99-106.


Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength.

Izon DJ, Punt JA, Xu L, Karnell FG, Allman D, Myung PS, Boerth NJ, Pui JC, Koretzky GA, Pear WS.

Immunity. 2001 Mar;14(3):253-64.


Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.

Aster JC, Xu L, Karnell FG, Patriub V, Pui JC, Pear WS.

Mol Cell Biol. 2000 Oct;20(20):7505-15.


Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

Pui JC, Allman D, Xu L, DeRocco S, Karnell FG, Bakkour S, Lee JY, Kadesch T, Hardy RR, Aster JC, Pear WS.

Immunity. 1999 Sep;11(3):299-308.

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