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Items: 38

1.

Positive maternal mental health during pregnancy associated with specific forms of adaptive development in early childhood: Evidence from a longitudinal study-CORRIGENDUM.

Phua DY, Kee MKZL, Koh DXP, Rifkin-Graboi A, Daniels M, Chen H, Chong YS, Broekman BFP, Magiati I, Karnani N, Pluess M, Meaney MJ; Growing Up In Singapore Towards Healthy Outcomes Study Group.

Dev Psychopathol. 2018 Aug 10:1. doi: 10.1017/S0954579418000858. [Epub ahead of print] No abstract available.

PMID:
30095064
2.

Optimizing drug combinations against multiple myeloma using a quadratic phenotypic optimization platform (QPOP).

Rashid MBMA, Toh TB, Hooi L, Silva A, Zhang Y, Tan PF, Teh AL, Karnani N, Jha S, Ho CM, Chng WJ, Ho D, Chow EK.

Sci Transl Med. 2018 Aug 8;10(453). pii: eaan0941. doi: 10.1126/scitranslmed.aan0941.

PMID:
30089632
3.

The early care environment and DNA methylome variation in childhood.

Garg E, Chen L, Nguyen TTT, Pokhvisneva I, Chen LM, Unternaehrer E, MacIsaac JL, McEwen LM, Mah SM, Gaudreau H, Levitan R, Moss E, Sokolowski MB, Kennedy JL, Steiner MS, Meaney MJ, Holbrook JD, Silveira PP, Karnani N, Kobor MS, O'Donnell KJ; Mavan Study Team.

Dev Psychopathol. 2018 Aug;30(3):891-903. doi: 10.1017/S0954579418000627.

PMID:
30068421
4.

TIP60 represses activation of endogenous retroviral elements.

Rajagopalan D, Tirado-Magallanes R, Bhatia SS, Teo WS, Sian S, Hora S, Lee KK, Zhang Y, Jadhav SP, Wu Y, Gan YH, Karnani N, Benoukraf T, Jha S.

Nucleic Acids Res. 2018 Jul 24. doi: 10.1093/nar/gky659. [Epub ahead of print]

PMID:
30053221
5.

Long-chain polyunsaturated fatty acids, gestation duration, and birth size: a Mendelian randomization study using fatty acid desaturase variants.

Bernard JY, Pan H, Aris IM, Moreno-Betancur M, Soh SE, Yap F, Tan KH, Shek LP, Chong YS, Gluckman PD, Calder PC, Godfrey KM, Chong MF, Kramer MS, Karnani N, Lee YS.

Am J Clin Nutr. 2018 Jul 1;108(1):92-100. doi: 10.1093/ajcn/nqy079.

PMID:
29878044
6.

Improving mass-univariate analysis of neuroimaging data by modelling important unknown covariates: Application to Epigenome-Wide Association Studies.

Guillaume B, Wang C, Poh J, Shen MJ, Ong ML, Tan PF, Karnani N, Meaney M, Qiu A.

Neuroimage. 2018 Jun;173:57-71. doi: 10.1016/j.neuroimage.2018.01.073. Epub 2018 Feb 12.

7.

DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-up.

O'Donnell KJ, Chen L, MacIsaac JL, McEwen LM, Nguyen T, Beckmann K, Zhu Y, Chen LM, Brooks-Gunn J, Goldman D, Grigorenko EL, Leckman JF, Diorio J, Karnani N, Olds DL, Holbrook JD, Kobor MS, Meaney MJ.

Transl Psychiatry. 2018 Jan 10;8(1):15. doi: 10.1038/s41398-017-0063-9.

8.

Choice of surrogate tissue influences neonatal EWAS findings.

Lin X, Teh AL, Chen L, Lim IY, Tan PF, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Lee YS, Holbrook JD, Godfrey KM, Meaney MJ, Kobor MS, Chong YS, Gluckman PD, Karnani N.

BMC Med. 2017 Dec 5;15(1):211. doi: 10.1186/s12916-017-0970-x.

9.

Positive maternal mental health during pregnancy associated with specific forms of adaptive development in early childhood: Evidence from a longitudinal study.

Phua DY, Kee MKZL, Koh DXP, Rifkin-Graboi A, Daniels M, Chen H, Chong YS, Broekman BFP, Magiati I, Karnani N, Pluess M, Meaney MJ; Growing Up In Singapore Towards Healthy Outcomes Study Group.

Dev Psychopathol. 2017 Dec;29(5):1573-1587. doi: 10.1017/S0954579417001249.

PMID:
29162171
10.

ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity.

Lillycrop K, Murray R, Cheong C, Teh AL, Clarke-Harris R, Barton S, Costello P, Garratt E, Cook E, Titcombe P, Shunmuganathan B, Liew SJ, Chua YC, Lin X, Wu Y, Burdge GC, Cooper C, Inskip HM, Karnani N, Hopkins JC, Childs CE, Chavez CP, Calder PC, Yap F, Lee YS, Chong YS, Melton PE, Beilin L, Huang RC, Gluckman PD, Harvey N, Hanson MA, Holbrook JD; EpiGen Consortium, Godfrey KM.

EBioMedicine. 2017 May;19:60-72. doi: 10.1016/j.ebiom.2017.03.037. Epub 2017 Apr 26.

11.

Gestational Diabetes Alters Functions in Offspring's Umbilical Cord Cells With Implications for Cardiovascular Health.

Amrithraj AI, Kodali A, Nguyen L, Teo AKK, Chang CW, Karnani N, Ng KL, Gluckman PD, Chong YS, Stünkel W.

Endocrinology. 2017 Jul 1;158(7):2102-2112. doi: 10.1210/en.2016-1889.

PMID:
28431037
12.

Effects of Antenatal Maternal Depressive Symptoms and Socio-Economic Status on Neonatal Brain Development are Modulated by Genetic Risk.

Qiu A, Shen M, Buss C, Chong YS, Kwek K, Saw SM, Gluckman PD, Wadhwa PD, Entringer S, Styner M, Karnani N, Heim CM, O'Donnell KJ, Holbrook JD, Fortier MV, Meaney MJ; the GUSTO study group.

Cereb Cortex. 2017 May 1;27(5):3080-3092. doi: 10.1093/cercor/bhx065.

13.

Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome.

Lin X, Lim IY, Wu Y, Teh AL, Chen L, Aris IM, Soh SE, Tint MT, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Holbrook JD, Lee YS, Gluckman PD, Karnani N; GUSTO study group.

BMC Med. 2017 Mar 7;15(1):50. doi: 10.1186/s12916-017-0800-1.

14.

TIP60 inhibits metastasis by ablating DNMT1-SNAIL2-driven epithelial-mesenchymal transition program.

Zhang Y, Subbaiah VK, Rajagopalan D, Tham CY, Abdullah LN, Toh TB, Gong M, Tan TZ, Jadhav SP, Pandey AK, Karnani N, Chow EK, Thiery JP, Jha S.

J Mol Cell Biol. 2016 Sep 20. pii: mjw038. [Epub ahead of print]

PMID:
27651430
15.

An Alternative Strategy for Pan-acetyl-lysine Antibody Generation.

Kim SY, Sim CK, Zhang Q, Tang H, Brunmeir R, Pan H, Karnani N, Han W, Zhang K, Xu F.

PLoS One. 2016 Sep 8;11(9):e0162528. doi: 10.1371/journal.pone.0162528. eCollection 2016.

17.

Comparison of Methyl-capture Sequencing vs. Infinium 450K methylation array for methylome analysis in clinical samples.

Teh AL, Pan H, Lin X, Lim YI, Patro CP, Cheong CY, Gong M, MacIsaac JL, Kwoh CK, Meaney MJ, Kobor MS, Chong YS, Gluckman PD, Holbrook JD, Karnani N.

Epigenetics. 2016;11(1):36-48. doi: 10.1080/15592294.2015.1132136. Epub 2016 Jan 19.

18.

Rate of establishing the gut microbiota in infancy has consequences for future health.

Dogra S, Sakwinska O, Soh SE, Ngom-Bru C, Brück WM, Berger B, Brüssow H, Karnani N, Lee YS, Yap F, Chong YS, Godfrey KM, Holbrook JD.

Gut Microbes. 2015;6(5):321-5. doi: 10.1080/19490976.2015.1078051. Epub 2015 Aug 20.

19.

HIF3A association with adiposity: the story begins before birth.

Pan H, Lin X, Wu Y, Chen L, Teh AL, Soh SE, Lee YS, Tint MT, MacIsaac JL, Morin AM, Tan KH, Yap F, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Gluckman PD, Karnani N, Holbrook JD; GUSTO Study Group.

Epigenomics. 2015;7(6):937-50. doi: 10.2217/epi.15.45. Epub 2015 May 26.

20.

Increased risk of Mycobacterium tuberculosis infection in household child contacts exposed to passive tobacco smoke.

Sridhar S, Karnani N, Connell DW, Millington KA, Dosanjh D, Bakir M, Soysal A, Deeks J, Lalvani A.

Pediatr Infect Dis J. 2014 Dec;33(12):1303-6. doi: 10.1097/INF.0000000000000506.

21.

The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes.

Teh AL, Pan H, Chen L, Ong ML, Dogra S, Wong J, MacIsaac JL, Mah SM, McEwen LM, Saw SM, Godfrey KM, Chong YS, Kwek K, Kwoh CK, Soh SE, Chong MF, Barton S, Karnani N, Cheong CY, Buschdorf JP, Stünkel W, Kobor MS, Meaney MJ, Gluckman PD, Holbrook JD.

Genome Res. 2014 Jul;24(7):1064-74. doi: 10.1101/gr.171439.113. Epub 2014 Apr 7.

22.

The effect of the intra-S-phase checkpoint on origins of replication in human cells.

Karnani N, Dutta A.

Genes Dev. 2011 Mar 15;25(6):621-33. doi: 10.1101/gad.2029711.

23.

Bubble-chip analysis of human origin distributions demonstrates on a genomic scale significant clustering into zones and significant association with transcription.

Mesner LD, Valsakumar V, Karnani N, Dutta A, Hamlin JL, Bekiranov S.

Genome Res. 2011 Mar;21(3):377-89. doi: 10.1101/gr.111328.110. Epub 2010 Dec 20. Erratum in: Genome Res. 2011 Sep;21(9):1561.

24.

CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation.

Abbas T, Shibata E, Park J, Jha S, Karnani N, Dutta A.

Mol Cell. 2010 Oct 8;40(1):9-21. doi: 10.1016/j.molcel.2010.09.014.

25.

Genomic study of replication initiation in human chromosomes reveals the influence of transcription regulation and chromatin structure on origin selection.

Karnani N, Taylor CM, Malhotra A, Dutta A.

Mol Biol Cell. 2010 Feb 1;21(3):393-404. doi: 10.1091/mbc.E09-08-0707. Epub 2009 Dec 2.

26.

Microarray analysis of DNA replication timing.

Karnani N, Taylor CM, Dutta A.

Methods Mol Biol. 2009;556:191-203. doi: 10.1007/978-1-60327-192-9_14.

27.

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

ENCODE Project Consortium, Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, Asthana S, Malhotra A, Adzhubei I, Greenbaum JA, Andrews RM, Flicek P, Boyle PJ, Cao H, Carter NP, Clelland GK, Davis S, Day N, Dhami P, Dillon SC, Dorschner MO, Fiegler H, Giresi PG, Goldy J, Hawrylycz M, Haydock A, Humbert R, James KD, Johnson BE, Johnson EM, Frum TT, Rosenzweig ER, Karnani N, Lee K, Lefebvre GC, Navas PA, Neri F, Parker SC, Sabo PJ, Sandstrom R, Shafer A, Vetrie D, Weaver M, Wilcox S, Yu M, Collins FS, Dekker J, Lieb JD, Tullius TD, Crawford GE, Sunyaev S, Noble WS, Dunham I, Denoeud F, Reymond A, Kapranov P, Rozowsky J, Zheng D, Castelo R, Frankish A, Harrow J, Ghosh S, Sandelin A, Hofacker IL, Baertsch R, Keefe D, Dike S, Cheng J, Hirsch HA, Sekinger EA, Lagarde J, Abril JF, Shahab A, Flamm C, Fried C, Hackermüller J, Hertel J, Lindemeyer M, Missal K, Tanzer A, Washietl S, Korbel J, Emanuelsson O, Pedersen JS, Holroyd N, Taylor R, Swarbreck D, Matthews N, Dickson MC, Thomas DJ, Weirauch MT, Gilbert J, Drenkow J, Bell I, Zhao X, Srinivasan KG, Sung WK, Ooi HS, Chiu KP, Foissac S, Alioto T, Brent M, Pachter L, Tress ML, Valencia A, Choo SW, Choo CY, Ucla C, Manzano C, Wyss C, Cheung E, Clark TG, Brown JB, Ganesh M, Patel S, Tammana H, Chrast J, Henrichsen CN, Kai C, Kawai J, Nagalakshmi U, Wu J, Lian Z, Lian J, Newburger P, Zhang X, Bickel P, Mattick JS, Carninci P, Hayashizaki Y, Weissman S, Hubbard T, Myers RM, Rogers J, Stadler PF, Lowe TM, Wei CL, Ruan Y, Struhl K, Gerstein M, Antonarakis SE, Fu Y, Green ED, Karaöz U, Siepel A, Taylor J, Liefer LA, Wetterstrand KA, Good PJ, Feingold EA, Guyer MS, Cooper GM, Asimenos G, Dewey CN, Hou M, Nikolaev S, Montoya-Burgos JI, Löytynoja A, Whelan S, Pardi F, Massingham T, Huang H, Zhang NR, Holmes I, Mullikin JC, Ureta-Vidal A, Paten B, Seringhaus M, Church D, Rosenbloom K, Kent WJ, Stone EA; NISC Comparative Sequencing Program; Baylor College of Medicine Human Genome Sequencing Center; Washington University Genome Sequencing Center; Broad Institute; Children's Hospital Oakland Research Institute, Batzoglou S, Goldman N, Hardison RC, Haussler D, Miller W, Sidow A, Trinklein ND, Zhang ZD, Barrera L, Stuart R, King DC, Ameur A, Enroth S, Bieda MC, Kim J, Bhinge AA, Jiang N, Liu J, Yao F, Vega VB, Lee CW, Ng P, Shahab A, Yang A, Moqtaderi Z, Zhu Z, Xu X, Squazzo S, Oberley MJ, Inman D, Singer MA, Richmond TA, Munn KJ, Rada-Iglesias A, Wallerman O, Komorowski J, Fowler JC, Couttet P, Bruce AW, Dovey OM, Ellis PD, Langford CF, Nix DA, Euskirchen G, Hartman S, Urban AE, Kraus P, Van Calcar S, Heintzman N, Kim TH, Wang K, Qu C, Hon G, Luna R, Glass CK, Rosenfeld MG, Aldred SF, Cooper SJ, Halees A, Lin JM, Shulha HP, Zhang X, Xu M, Haidar JN, Yu Y, Ruan Y, Iyer VR, Green RD, Wadelius C, Farnham PJ, Ren B, Harte RA, Hinrichs AS, Trumbower H, Clawson H, Hillman-Jackson J, Zweig AS, Smith K, Thakkapallayil A, Barber G, Kuhn RM, Karolchik D, Armengol L, Bird CP, de Bakker PI, Kern AD, Lopez-Bigas N, Martin JD, Stranger BE, Woodroffe A, Davydov E, Dimas A, Eyras E, Hallgrímsdóttir IB, Huppert J, Zody MC, Abecasis GR, Estivill X, Bouffard GG, Guan X, Hansen NF, Idol JR, Maduro VV, Maskeri B, McDowell JC, Park M, Thomas PJ, Young AC, Blakesley RW, Muzny DM, Sodergren E, Wheeler DA, Worley KC, Jiang H, Weinstock GM, Gibbs RA, Graves T, Fulton R, Mardis ER, Wilson RK, Clamp M, Cuff J, Gnerre S, Jaffe DB, Chang JL, Lindblad-Toh K, Lander ES, Koriabine M, Nefedov M, Osoegawa K, Yoshinaga Y, Zhu B, de Jong PJ.

Nature. 2007 Jun 14;447(7146):799-816.

28.
29.

Nuclear localization of RFC40 by RIalpha: a link between cellular signaling and proliferation.

Karnani N, Dutta A.

Cancer Biol Ther. 2005 Apr;4(4):438-9. Epub 2005 Apr 29. No abstract available.

PMID:
15908789
30.

Evaluation of chronic dyspnea.

Karnani NG, Reisfield GM, Wilson GR.

Am Fam Physician. 2005 Apr 15;71(8):1529-37. Review.

31.

Temporal profile of replication of human chromosomes.

Jeon Y, Bekiranov S, Karnani N, Kapranov P, Ghosh S, MacAlpine D, Lee C, Hwang DS, Gingeras TR, Dutta A.

Proc Natl Acad Sci U S A. 2005 May 3;102(18):6419-24. Epub 2005 Apr 21.

32.
33.

Genome-wide expression profile of steroid response in Saccharomyces cerevisiae.

Banerjee D, Pillai B, Karnani N, Mukhopadhyay G, Prasad R.

Biochem Biophys Res Commun. 2004 Apr 30;317(2):406-13.

PMID:
15063773
34.

SRE1 and SRE2 are two specific steroid-responsive modules of Candida drug resistance gene 1 (CDR1) promoter.

Karnani N, Gaur NA, Jha S, Puri N, Krishnamurthy S, Goswami SK, Mukhopadhyay G, Prasad R.

Yeast. 2004 Feb;21(3):219-39.

35.

Identification of a negative regulatory element which regulates basal transcription of a multidrug resistance gene CDR1 of Candida albicans.

Gaur NA, Puri N, Karnani N, Mukhopadhyay G, Goswami SK, Prasad R.

FEMS Yeast Res. 2004 Jan;4(4-5):389-99.

36.

Covalent modification of cysteine 193 impairs ATPase function of nucleotide-binding domain of a Candida drug efflux pump.

Jha S, Karnani N, Lynn AM, Prasad R.

Biochem Biophys Res Commun. 2003 Oct 24;310(3):869-75.

PMID:
14550284
37.

Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis.

Jha S, Karnani N, Dhar SK, Mukhopadhayay K, Shukla S, Saini P, Mukhopadhayay G, Prasad R.

Biochemistry. 2003 Sep 16;42(36):10822-32.

PMID:
12962507
38.

Molecular cloning and functional characterisation of a glucose transporter, CaHGT1, of Candida albicans.

Varma A, Singh BB, Karnani N, Lichtenberg-Fraté H, Höfer M, Magee BB, Prasad R.

FEMS Microbiol Lett. 2000 Jan 1;182(1):15-21.

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