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Items: 1 to 50 of 52

1.

Establishment and characterization of a novel vincristine-resistant diffuse large B-cell lymphoma cell line containing the 8q24 homogeneously staining region.

Mizuno S, Hanamura I, Ota A, Karnan S, Kanasugi J, Nakamura A, Takasugi S, Uchino K, Horio T, Goto M, Murakami S, Gotou M, Yamamoto H, Watarai M, Shikami M, Hosokawa Y, Miwa H, Taniwaki M, Ueda R, Nitta M, Takami A.

FEBS Open Bio. 2018 Nov 20;8(12):1977-1991. doi: 10.1002/2211-5463.12538. eCollection 2018 Dec.

2.

Establishment and characterization of CRISPR/Cas9-mediated NF2-/- human mesothelial cell line: Molecular insight into fibroblast growth factor receptor 2 in malignant pleural mesothelioma.

Wahiduzzaman M, Karnan S, Ota A, Hanamura I, Murakami H, Inoko A, Rahman ML, Hyodo T, Konishi H, Tsuzuki S, Hosokawa Y.

Cancer Sci. 2019 Jan;110(1):180-193. doi: 10.1111/cas.13871. Epub 2018 Dec 14.

3.

The plant alkaloid conophylline inhibits matrix formation of fibroblasts.

Tezuka T, Ota A, Karnan S, Matsuura K, Yokoo K, Hosokawa Y, Vigetti D, Passi A, Hatano S, Umezawa K, Watanabe H.

J Biol Chem. 2018 Dec 28;293(52):20214-20226. doi: 10.1074/jbc.RA118.005783. Epub 2018 Oct 30.

PMID:
30377255
4.

Generation of PTEN‑knockout (‑/‑) murine prostate cancer cells using the CRISPR/Cas9 system and comprehensive gene expression profiling.

Takao A, Yoshikawa K, Karnan S, Ota A, Uemura H, De Velasco MA, Kura Y, Suzuki S, Ueda R, Nishino T, Hosokawa Y.

Oncol Rep. 2018 Nov;40(5):2455-2466. doi: 10.3892/or.2018.6683. Epub 2018 Sep 5.

PMID:
30226608
5.

Novel combined Ato-C treatment synergistically suppresses proliferation of Bcr-Abl-positive leukemic cells in vitro and in vivo.

Wahiduzzaman M, Ota A, Karnan S, Hanamura I, Mizuno S, Kanasugi J, Rahman ML, Hyodo T, Konishi H, Tsuzuki S, Takami A, Hosokawa Y.

Cancer Lett. 2018 Oct 1;433:117-130. doi: 10.1016/j.canlet.2018.06.027. Epub 2018 Jun 23.

PMID:
29944906
6.

Inhibition of NADPH oxidase 2 induces apoptosis in osteosarcoma: The role of reactive oxygen species in cell proliferation.

Kitamoto K, Miura Y, Karnan S, Ota A, Konishi H, Hosokawa Y, Sato K.

Oncol Lett. 2018 May;15(5):7955-7962. doi: 10.3892/ol.2018.8291. Epub 2018 Mar 19.

7.

Novel ATP-competitive Akt inhibitor afuresertib suppresses the proliferation of malignant pleural mesothelioma cells.

Yamaji M, Ota A, Wahiduzzaman M, Karnan S, Hyodo T, Konishi H, Tsuzuki S, Hosokawa Y, Haniuda M.

Cancer Med. 2017 Nov;6(11):2646-2659. doi: 10.1002/cam4.1179. Epub 2017 Sep 27.

8.

Versican A-subdomain is required for its adequate function in dermal development.

Hatano S, Nagai N, Sugiura N, Tsuchimoto J, Isogai Z, Kimata K, Ota A, Karnan S, Hosokawa Y, Watanabe H.

Connect Tissue Res. 2018 Mar;59(2):178-190. doi: 10.1080/03008207.2017.1324432. Epub 2017 Jun 8.

PMID:
28488903
9.

Confounding features of ectopic craniopharyngioma: A differential for tumors showing diffusion restriction.

Karnan S, Krishnamoorthy V, Natarajan K, Sathyanathan BP.

Asian J Neurosurg. 2017 Jan-Mar;12(1):123-126. doi: 10.4103/1793-5482.149999.

10.

Δ40p53α suppresses tumor cell proliferation and induces cellular senescence in hepatocellular carcinoma cells.

Ota A, Nakao H, Sawada Y, Karnan S, Wahiduzzaman M, Inoue T, Kobayashi Y, Yamamoto T, Ishii N, Ohashi T, Nakade Y, Sato K, Itoh K, Konishi H, Hosokawa Y, Yoneda M.

J Cell Sci. 2017 Feb 1;130(3):614-625. doi: 10.1242/jcs.190736. Epub 2016 Dec 15.

11.

Inhibition of Nox1 induces apoptosis by attenuating the AKT signaling pathway in oral squamous cell carcinoma cell lines.

Ito K, Ota A, Ono T, Nakaoka T, Wahiduzzaman M, Karnan S, Konishi H, Furuhashi A, Hayashi T, Yamada Y, Hosokawa Y, Kazaoka Y.

Oncol Rep. 2016 Nov;36(5):2991-2998. doi: 10.3892/or.2016.5068. Epub 2016 Sep 5.

PMID:
27600098
12.

Improved methods of AAV-mediated gene targeting for human cell lines using ribosome-skipping 2A peptide.

Karnan S, Ota A, Konishi Y, Wahiduzzaman M, Hosokawa Y, Konishi H.

Nucleic Acids Res. 2016 Apr 7;44(6):e54. doi: 10.1093/nar/gkv1338. Epub 2015 Dec 10.

13.

Overexpression of salivary-type amylase reduces the sensitivity to bortezomib in multiple myeloma cells.

Mizuno S, Hanamura I, Ota A, Karnan S, Narita T, Ri M, Mizutani M, Goto M, Gotou M, Tsunekawa N, Shikami M, Iida S, Hosokawa Y, Miwa H, Ueda R, Nitta M, Takami A.

Int J Hematol. 2015 Nov;102(5):569-78. doi: 10.1007/s12185-015-1859-0. Epub 2015 Sep 4.

PMID:
26341959
14.

Inhibition of NADPH oxidase 4 induces apoptosis in malignant mesothelioma: Role of reactive oxygen species.

Tanaka M, Miura Y, Numanami H, Karnan S, Ota A, Konishi H, Hosokawa Y, Hanyuda M.

Oncol Rep. 2015 Oct;34(4):1726-32. doi: 10.3892/or.2015.4155. Epub 2015 Jul 27.

PMID:
26238284
15.

Plumbagin suppresses tumor cell growth in oral squamous cell carcinoma cell lines.

Ono T, Ota A, Ito K, Nakaoka T, Karnan S, Konishi H, Furuhashi A, Hayashi T, Yamada Y, Hosokawa Y, Kazaoka Y.

Oral Dis. 2015 May;21(4):501-11. doi: 10.1111/odi.12310. Epub 2015 Jan 29.

PMID:
25580997
16.

High-resolution 400K oligonucleotide array comparative genomic hybridization analysis of neurofibromatosis type 1-associated cutaneous neurofibromas.

Asai A, Karnan S, Ota A, Takahashi M, Damdindorj L, Konishi Y, Hossain E, Konishi H, Nagata A, Yokoo K, Hosokawa Y.

Gene. 2015 Mar 10;558(2):220-6. doi: 10.1016/j.gene.2014.12.064. Epub 2015 Jan 3.

PMID:
25562418
17.

Lipopolysaccharide augments the uptake of oxidized LDL by up-regulating lectin-like oxidized LDL receptor-1 in macrophages.

Hossain E, Ota A, Karnan S, Takahashi M, Mannan SB, Konishi H, Hosokawa Y.

Mol Cell Biochem. 2015 Feb;400(1-2):29-40. doi: 10.1007/s11010-014-2259-0. Epub 2014 Oct 28.

PMID:
25348362
18.

A comparative analysis of constitutive promoters located in adeno-associated viral vectors.

Damdindorj L, Karnan S, Ota A, Hossain E, Konishi Y, Hosokawa Y, Konishi H.

PLoS One. 2014 Aug 29;9(8):e106472. doi: 10.1371/journal.pone.0106472. eCollection 2014.

19.
20.

Clonal heterogeneity of lymphoid malignancies correlates with poor prognosis.

Suguro M, Yoshida N, Umino A, Kato H, Tagawa H, Nakagawa M, Fukuhara N, Karnan S, Takeuchi I, Hocking TD, Arita K, Karube K, Tsuzuki S, Nakamura S, Kinoshita T, Seto M.

Cancer Sci. 2014 Jul;105(7):897-904. doi: 10.1111/cas.12442. Epub 2014 Jul 1.

21.

Combined arsenic trioxide-cisplatin treatment enhances apoptosis in oral squamous cell carcinoma cells.

Nakaoka T, Ota A, Ono T, Karnan S, Konishi H, Furuhashi A, Ohmura Y, Yamada Y, Hosokawa Y, Kazaoka Y.

Cell Oncol (Dordr). 2014 Apr;37(2):119-29. doi: 10.1007/s13402-014-0167-7. Epub 2014 Mar 6.

PMID:
24599717
22.

Arsenic augments the uptake of oxidized LDL by upregulating the expression of lectin-like oxidized LDL receptor in mouse aortic endothelial cells.

Hossain E, Ota A, Karnan S, Damdindorj L, Takahashi M, Konishi Y, Konishi H, Hosokawa Y.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):651-8. doi: 10.1016/j.taap.2013.10.012. Epub 2013 Oct 19.

PMID:
24145059
23.

Touraine-Solente-Gole syndrome: The complete form needs to be recognized.

Karnan S, Krishnamoorthy V, Ethiraj P, Sathyanathan BP.

Indian J Nucl Med. 2012 Jul;27(3):201-4. doi: 10.4103/0972-3919.112743.

24.

Arsenic upregulates the expression of angiotensin II Type I receptor in mouse aortic endothelial cells.

Hossain E, Ota A, Takahashi M, Karnan S, Damdindorj L, Konishi Y, Konishi H, Hosokawa Y.

Toxicol Lett. 2013 Jun 20;220(1):70-5. doi: 10.1016/j.toxlet.2013.04.006. Epub 2013 Apr 17.

PMID:
23603059
25.

Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation.

Wang GM, Wong HY, Konishi H, Blair BG, Abukhdeir AM, Gustin JP, Rosen DM, Denmeade SR, Rasheed Z, Matsui W, Garay JP, Mohseni M, Higgins MJ, Cidado J, Jelovac D, Croessmann S, Cochran RL, Karnan S, Konishi Y, Ota A, Hosokawa Y, Argani P, Lauring J, Park BH.

Cancer Res. 2013 Jun 1;73(11):3248-61. doi: 10.1158/0008-5472.CAN-12-1578. Epub 2013 Apr 11.

26.

Arsenic trioxide prevents nitric oxide production in lipopolysaccharide -stimulated RAW 264.7 by inhibiting a TRIF-dependent pathway.

Takahashi M, Ota A, Karnan S, Hossain E, Konishi Y, Damdindorj L, Konishi H, Yokochi T, Nitta M, Hosokawa Y.

Cancer Sci. 2013 Feb;104(2):165-70. doi: 10.1111/cas.12053. Epub 2012 Dec 13.

27.

Simple monitoring of gene targeting efficiency in human somatic cell lines using the PIGA gene.

Karnan S, Konishi Y, Ota A, Takahashi M, Damdindorj L, Hosokawa Y, Konishi H.

PLoS One. 2012;7(10):e47389. doi: 10.1371/journal.pone.0047389. Epub 2012 Oct 8.

28.

A system for the measurement of gene targeting efficiency in human cell lines using an antibiotic resistance-GFP fusion gene.

Konishi Y, Karnan S, Takahashi M, Ota A, Damdindorj L, Hosokawa Y, Konishi H.

Biotechniques. 2012 Sep;53(3):141-52. doi: 10.2144/0000113911.

29.

Assessment of the long-term transcriptional activity of a 550-bp-long human β-actin promoter region.

Damdindorj L, Karnan S, Ota A, Takahashi M, Konishi Y, Hossain E, Hosokawa Y, Konishi H.

Plasmid. 2012 Nov;68(3):195-200. doi: 10.1016/j.plasmid.2012.07.003. Epub 2012 Jul 28.

PMID:
22846724
30.

Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells.

Konishi H, Mohseni M, Tamaki A, Garay JP, Croessmann S, Karnan S, Ota A, Wong HY, Konishi Y, Karakas B, Tahir K, Abukhdeir AM, Gustin JP, Cidado J, Wang GM, Cosgrove D, Cochran R, Jelovac D, Higgins MJ, Arena S, Hawkins L, Lauring J, Gross AL, Heaphy CM, Hosokawa Y, Gabrielson E, Meeker AK, Visvanathan K, Argani P, Bachman KE, Park BH.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17773-8. doi: 10.1073/pnas.1110969108. Epub 2011 Oct 10.

31.

Genomic profiling combined with gene expression profiling in primary central nervous system lymphoma.

Sung CO, Kim SC, Karnan S, Karube K, Shin HJ, Nam DH, Suh YL, Kim SH, Kim JY, Kim SJ, Kim WS, Seto M, Ko YH.

Blood. 2011 Jan 27;117(4):1291-300. doi: 10.1182/blood-2010-07-297861. Epub 2010 Nov 18.

PMID:
21088137
32.

Enteropathy-associated T-cell lymphoma--a clinicopathologic and array comparative genomic hybridization study.

Ko YH, Karnan S, Kim KM, Park CK, Kang ES, Kim YH, Kang WK, Kim SJ, Kim WS, Lee WY, Chun HK, Seto M.

Hum Pathol. 2010 Sep;41(9):1231-7. doi: 10.1016/j.humpath.2009.11.020. Epub 2010 Apr 18.

PMID:
20399483
33.

Controversial BRCA1 allelotypes in commonly used breast cancer cell lines.

Karnan S, Mohseni M, Konishi Y, Tamaki A, Hosokawa Y, Park BH, Konishi H.

Breast Cancer Res Treat. 2010 Jan;119(1):249-51. doi: 10.1007/s10549-009-0465-3. Epub 2009 Jul 8. No abstract available.

34.

Array comparative genomic hybridization analysis of PTCL-U reveals a distinct subgroup with genetic alterations similar to lymphoma-type adult T-cell leukemia/lymphoma.

Nakagawa M, Nakagawa-Oshiro A, Karnan S, Tagawa H, Utsunomiya A, Nakamura S, Takeuchi I, Ohshima K, Seto M.

Clin Cancer Res. 2009 Jan 1;15(1):30-8. doi: 10.1158/1078-0432.CCR-08-1808.

35.

Genome-wide analysis of DNA copy number alterations and gene expression in gastric cancer.

Tsukamoto Y, Uchida T, Karnan S, Noguchi T, Nguyen LT, Tanigawa M, Takeuchi I, Matsuura K, Hijiya N, Nakada C, Kishida T, Kawahara K, Ito H, Murakami K, Fujioka T, Seto M, Moriyama M.

J Pathol. 2008 Dec;216(4):471-82. doi: 10.1002/path.2424.

PMID:
18798223
36.

High-resolution analysis of DNA copy number alterations and gene expression in renal clear cell carcinoma.

Yoshimoto T, Matsuura K, Karnan S, Tagawa H, Nakada C, Tanigawa M, Tsukamoto Y, Uchida T, Kashima K, Akizuki S, Takeuchi I, Sato F, Mimata H, Seto M, Moriyama M.

J Pathol. 2007 Dec;213(4):392-401.

PMID:
17922474
37.

TNFAIP3 is the target gene of chromosome band 6q23.3-q24.1 loss in ocular adnexal marginal zone B cell lymphoma.

Honma K, Tsuzuki S, Nakagawa M, Karnan S, Aizawa Y, Kim WS, Kim YD, Ko YH, Seto M.

Genes Chromosomes Cancer. 2008 Jan;47(1):1-7.

PMID:
17886247
38.

Genome-wide array-based comparative genomic hybridization of ocular marginal zone B cell lymphoma: comparison with pulmonary and nodal marginal zone B cell lymphoma.

Kim WS, Honma K, Karnan S, Tagawa H, Kim YD, Oh YL, Seto M, Ko YH.

Genes Chromosomes Cancer. 2007 Aug;46(8):776-83.

PMID:
17492759
39.

[Array CGH analysis for malignant lymphoma].

Seto M, Karnan S, Tagawa H.

Nihon Rinsho. 2007 Jan 28;65 Suppl 1:182-8. Review. Japanese. No abstract available.

PMID:
17474411
40.

Genetic abnormalities involved in t(12;21) TEL-AML1 acute lymphoblastic leukemia: analysis by means of array-based comparative genomic hybridization.

Tsuzuki S, Karnan S, Horibe K, Matsumoto K, Kato K, Inukai T, Goi K, Sugita K, Nakazawa S, Kasugai Y, Ueda R, Seto M.

Cancer Sci. 2007 May;98(5):698-706. Epub 2007 Mar 21.

41.

Genomic profiling of malignant pleural mesothelioma with array-based comparative genomic hybridization shows frequent non-random chromosomal alteration regions including JUN amplification on 1p32.

Taniguchi T, Karnan S, Fukui T, Yokoyama T, Tagawa H, Yokoi K, Ueda Y, Mitsudomi T, Horio Y, Hida T, Yatabe Y, Seto M, Sekido Y.

Cancer Sci. 2007 Mar;98(3):438-46.

42.

Characterization of target genes at the 2p15-16 amplicon in diffuse large B-cell lymphoma.

Fukuhara N, Tagawa H, Kameoka Y, Kasugai Y, Karnan S, Kameoka J, Sasaki T, Morishima Y, Nakamura S, Seto M.

Cancer Sci. 2006 Jun;97(6):499-504.

43.

Genomewide array-based comparative genomic hybridization analysis of acute promyelocytic leukemia.

Karnan S, Tsuzuki S, Kiyoi H, Tagawa H, Ueda R, Seto M, Naoe T.

Genes Chromosomes Cancer. 2006 Apr;45(4):420-5.

PMID:
16419057
44.

Genome-wide array-based comparative genomic hybridization of natural killer cell lymphoma/leukemia: different genomic alteration patterns of aggressive NK-cell leukemia and extranodal Nk/T-cell lymphoma, nasal type.

Nakashima Y, Tagawa H, Suzuki R, Karnan S, Karube K, Ohshima K, Muta K, Nawata H, Morishima Y, Nakamura S, Seto M.

Genes Chromosomes Cancer. 2005 Nov;44(3):247-55.

PMID:
16049916
45.

Comparison of genome profiles for identification of distinct subgroups of diffuse large B-cell lymphoma.

Tagawa H, Suguro M, Tsuzuki S, Matsuo K, Karnan S, Ohshima K, Okamoto M, Morishima Y, Nakamura S, Seto M.

Blood. 2005 Sep 1;106(5):1770-7. Epub 2005 May 10. Erratum in: Blood. 2006 Apr 15;107(8):3052.

PMID:
15886317
46.

Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM.

Tagawa H, Karnan S, Suzuki R, Matsuo K, Zhang X, Ota A, Morishima Y, Nakamura S, Seto M.

Oncogene. 2005 Feb 17;24(8):1348-58.

PMID:
15608680
47.

Comparison of genetic aberrations in CD10+ diffused large B-cell lymphoma and follicular lymphoma by comparative genomic hybridization and tissue-fluorescence in situ hybridization.

Zhang X, Karnan S, Tagawa H, Suzuki R, Tsuzuki S, Hosokawa Y, Morishima Y, Nakamura S, Seto M.

Cancer Sci. 2004 Oct;95(10):809-14.

48.

Contig array CGH at 3p14.2 points to the FRA3B/FHIT common fragile region as the target gene in diffuse large B-cell lymphoma.

Kameoka Y, Tagawa H, Tsuzuki S, Karnan S, Ota A, Suguro M, Suzuki R, Yamaguchi M, Morishima Y, Nakamura S, Seto M.

Oncogene. 2004 Dec 2;23(56):9148-54.

PMID:
15480422
49.

Genome-wide array-based comparative genomic hybridization of diffuse large B-cell lymphoma: comparison between CD5-positive and CD5-negative cases.

Tagawa H, Tsuzuki S, Suzuki R, Karnan S, Ota A, Kameoka Y, Suguro M, Matsuo K, Yamaguchi M, Okamoto M, Morishima Y, Nakamura S, Seto M.

Cancer Res. 2004 Sep 1;64(17):5948-55.

50.

Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma.

Ota A, Tagawa H, Karnan S, Tsuzuki S, Karpas A, Kira S, Yoshida Y, Seto M.

Cancer Res. 2004 May 1;64(9):3087-95.

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