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Items: 22

1.

Efficient CD4Cre-Mediated Conditional KRas Expression in Alveolar Macrophages and Alveolar Epithelial Cells Causes Fatal Hyperproliferative Pneumonitis.

Chen P, Wang S, Janardhan KS, Zemans RL, Deng W, Karmaus P, Shen S, Sunday M, Que LG, Fessler MB, Zhong XP.

J Immunol. 2019 Sep 1;203(5):1208-1217. doi: 10.4049/jimmunol.1900566. Epub 2019 Jul 17.

PMID:
31315887
2.

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.

Karmaus PWF, Chen X, Lim SA, Herrada AA, Nguyen TM, Xu B, Dhungana Y, Rankin S, Chen W, Rosencrance C, Yang K, Fan Y, Cheng Y, Easton J, Neale G, Vogel P, Chi H.

Nature. 2019 Jan;565(7737):101-105. doi: 10.1038/s41586-018-0806-7. Epub 2018 Dec 19.

3.

Challenges for Integrating Immunotoxicology into the Twenty-First-Century Toxicology Testing Paradigm.

Karmaus PWF, Karmaus AL.

Methods Mol Biol. 2018;1803:385-396. doi: 10.1007/978-1-4939-8549-4_23.

PMID:
29882151
4.

Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells.

Du X, Wen J, Wang Y, Karmaus PWF, Khatamian A, Tan H, Li Y, Guy C, Nguyen TM, Dhungana Y, Neale G, Peng J, Yu J, Chi H.

Nature. 2018 Jun;558(7708):141-145. doi: 10.1038/s41586-018-0177-0. Epub 2018 May 30.

5.

Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.

Karmaus PWF, Herrada AA, Guy C, Neale G, Dhungana Y, Long L, Vogel P, Avila J, Clish CB, Chi H.

J Exp Med. 2017 Sep 4;214(9):2629-2647. doi: 10.1084/jem.20161855. Epub 2017 Aug 7.

6.

Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis.

Qi X, Gurung P, Malireddi RK, Karmaus PW, Sharma D, Vogel P, Chi H, Green DR, Kanneganti TD.

Mucosal Immunol. 2017 Jan;10(1):128-138. doi: 10.1038/mi.2016.25. Epub 2016 Mar 23.

7.

Contributions of nonhematopoietic cells and mediators to immune responses: implications for immunotoxicology.

Kaplan BL, Li J, LaPres JJ, Pruett SB, Karmaus PW.

Toxicol Sci. 2015 Jun;145(2):214-32. doi: 10.1093/toxsci/kfv060. Review.

8.

mTOR and metabolic regulation of conventional and regulatory T cells.

Liu C, Chapman NM, Karmaus PW, Zeng H, Chi H.

J Leukoc Biol. 2015 May;97(5):837-847. doi: 10.1189/jlb.2RI0814-408R. Epub 2015 Feb 24. Review.

9.

Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs.

Shrestha S, Yang K, Wei J, Karmaus PW, Neale G, Chi H.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14858-63. doi: 10.1073/pnas.1404264111. Epub 2014 Sep 30.

10.

c-Myc and AP4: a relay team for metabolic reprogramming of CD8+ T cells.

Karmaus PW, Chi H.

Nat Immunol. 2014 Sep;15(9):828-9. doi: 10.1038/ni.2962. No abstract available.

PMID:
25137465
11.

Genetic dissection of dendritic cell homeostasis and function: lessons from cell type-specific gene ablation.

Karmaus PW, Chi H.

Cell Mol Life Sci. 2014 May;71(10):1893-906. doi: 10.1007/s00018-013-1534-7. Epub 2013 Dec 24. Review.

12.

T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.

Yang K, Shrestha S, Zeng H, Karmaus PW, Neale G, Vogel P, Guertin DA, Lamb RF, Chi H.

Immunity. 2013 Dec 12;39(6):1043-56. doi: 10.1016/j.immuni.2013.09.015. Epub 2013 Dec 5.

13.

Cannabidiol (CBD) enhances lipopolysaccharide (LPS)-induced pulmonary inflammation in C57BL/6 mice.

Karmaus PW, Wagner JG, Harkema JR, Kaminski NE, Kaplan BL.

J Immunotoxicol. 2013 Jul-Sep;10(3):321-8. doi: 10.3109/1547691X.2012.741628. Epub 2012 Nov 23.

14.

Δ9-tetrahydrocannabinol impairs the inflammatory response to influenza infection: role of antigen-presenting cells and the cannabinoid receptors 1 and 2.

Karmaus PW, Chen W, Crawford R, Kaplan BL, Kaminski NE.

Toxicol Sci. 2013 Feb;131(2):419-33. doi: 10.1093/toxsci/kfs315. Epub 2012 Nov 14.

15.

Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection.

Karmaus PW, Chen W, Crawford RB, Harkema JR, Kaplan BL, Kaminski NE.

J Leukoc Biol. 2011 Nov;90(5):983-95. doi: 10.1189/jlb.0511219. Epub 2011 Aug 26.

16.

Δ9-tetrahydrocannabinol suppresses cytotoxic T lymphocyte function independent of CB1 and CB 2, disrupting early activation events.

Karmaus PW, Chen W, Kaplan BL, Kaminski NE.

J Neuroimmune Pharmacol. 2012 Dec;7(4):843-55. doi: 10.1007/s11481-011-9293-4. Epub 2011 Jul 26.

17.

The effects of targeted deletion of cannabinoid receptors CB1 and CB2 on intranasal sensitization and challenge with adjuvant-free ovalbumin.

Kaplan BL, Lawver JE, Karmaus PW, Ngaotepprutaram T, Birmingham NP, Harkema JR, Kaminski NE.

Toxicol Pathol. 2010 Apr;38(3):382-92. doi: 10.1177/0192623310362706. Epub 2010 Feb 26.

18.

Effects of targeted deletion of cannabinoid receptors CB1 and CB2 on immune competence and sensitivity to immune modulation by Delta9-tetrahydrocannabinol.

Springs AE, Karmaus PW, Crawford RB, Kaplan BL, Kaminski NE.

J Leukoc Biol. 2008 Dec;84(6):1574-84. doi: 10.1189/jlb.0508282. Epub 2008 Sep 12.

19.

Targeted deletion of cannabinoid receptors CB1 and CB2 produced enhanced inflammatory responses to influenza A/PR/8/34 in the absence and presence of Δ9 -tetrahydrocannabinol.

Buchweitz JP, Karmaus PWF, Williams KJ, Harkema JR, Kaminski NE.

J Leukoc Biol. 2008 Mar;83(3):785-796. doi: 10.1189/jlb.0907618.

PMID:
29350853
20.

Targeted deletion of cannabinoid receptors CB1 and CB2 produced enhanced inflammatory responses to influenza A/PR/8/34 in the absence and presence of Delta9-tetrahydrocannabinol.

Buchweitz JP, Karmaus PW, Williams KJ, Harkema JR, Kaminski NE.

J Leukoc Biol. 2008 Mar;83(3):785-96. Epub 2007 Dec 11.

PMID:
18073275
21.

Modulation of airway responses to influenza A/PR/8/34 by Delta9-tetrahydrocannabinol in C57BL/6 mice.

Buchweitz JP, Karmaus PW, Harkema JR, Williams KJ, Kaminski NE.

J Pharmacol Exp Ther. 2007 Nov;323(2):675-83. Epub 2007 Aug 28.

PMID:
17726158
22.

2,2',4,4'-Tetrachlorobiphenyl upregulates cyclooxygenase-2 in HL-60 cells via p38 mitogen-activated protein kinase and NF-kappaB.

Bezdecny SA, Karmaus P, Roth RA, Ganey PE.

Toxicol Appl Pharmacol. 2007 Jun 15;221(3):285-94. Epub 2007 Mar 30.

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