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Items: 31

1.

Commentary on the EMA Reflection Paper on the use of extrapolation in the development of medicines for paediatrics.

Ollivier C, Thomson A, Manolis E, Blake K, Karlsson KE, Knibbe CAJ, Pons G, Hemmings R.

Br J Clin Pharmacol. 2019 Apr;85(4):659-668. doi: 10.1111/bcp.13883. Epub 2019 Feb 28.

PMID:
30707770
2.

Commentary on the MID3 Good Practices Paper.

Manolis E, Brogren J, Cole S, Hay JL, Nordmark A, Karlsson KE, Lentz F, Benda N, Wangorsch G, Pons G, Zhao W, Gigante V, Serone F, Standing JF, Dokoumetzidis A, Vakkilainen J, van den Heuvel M, Mangas Sanjuan V, Taminiau J, Kerwash E, Khan D, Musuamba FT, Skottheim Rusten I; EMA Modelling and Simulation Working Group.

CPT Pharmacometrics Syst Pharmacol. 2017 Jul;6(7):416-417. doi: 10.1002/psp4.12223. Epub 2017 Jul 22.

3.

Edoxaban Exposure-Response Analysis and Clinical Utility Index Assessment in Patients With Symptomatic Deep-Vein Thrombosis or Pulmonary Embolism.

Nyberg J, Karlsson KE, Jönsson S, Yin O, Miller R, Karlsson MO, Simonsson U.

CPT Pharmacometrics Syst Pharmacol. 2016 Apr;5(4):222-32. doi: 10.1002/psp4.12077. Epub 2016 Apr 15.

4.

Population Pharmacokinetics of Edoxaban in Patients with Non-Valvular Atrial Fibrillation in the ENGAGE AF-TIMI 48 Study, a Phase III Clinical Trial.

Krekels EH, Niebecker R, Karlsson MO, Miller R, Shimizu T, Karlsson KE, Ruff CT, Simonsson US, Jönsson S.

Clin Pharmacokinet. 2016 Sep;55(9):1079-90. doi: 10.1007/s40262-016-0378-3.

PMID:
26951208
5.

Comparisons of Analysis Methods for Proof-of-Concept Trials.

Karlsson KE, Vong C, Bergstrand M, Jonsson EN, Karlsson MO.

CPT Pharmacometrics Syst Pharmacol. 2013 Jan 16;2:e23. doi: 10.1038/psp.2012.24.

6.

Performance of three estimation methods in repeated time-to-event modeling.

Karlsson KE, Plan EL, Karlsson MO.

AAPS J. 2011 Mar;13(1):83-91. doi: 10.1208/s12248-010-9248-3. Epub 2011 Jan 13.

7.

Modeling disease progression in acute stroke using clinical assessment scales.

Karlsson KE, Wilkins JJ, Jonsson F, Zingmark PH, Karlsson MO, Jonsson EN.

AAPS J. 2010 Dec;12(4):683-91. doi: 10.1208/s12248-010-9230-0. Epub 2010 Sep 21.

8.

Approaches to simultaneous analysis of frequency and severity of symptoms.

Plan EL, Karlsson KE, Karlsson MO.

Clin Pharmacol Ther. 2010 Aug;88(2):255-9. doi: 10.1038/clpt.2010.118. Epub 2010 Jul 7. Review. No abstract available.

PMID:
20613722
9.

Randomized exposure-controlled trials; impact of randomization and analysis strategies.

Karlsson KE, Grahnén A, Karlsson MO, Jonsson EN.

Br J Clin Pharmacol. 2007 Sep;64(3):266-77. Epub 2007 Apr 10.

10.

Diurnal variation in serum levels of cartilage oligomeric matrix protein in patients with knee osteoarthritis or rheumatoid arthritis.

Andersson ML, Petersson IF, Karlsson KE, Jonsson EN, Månsson B, Heinegård D, Saxne T.

Ann Rheum Dis. 2006 Nov;65(11):1490-4. Epub 2006 May 17.

11.

Derivatization using dimethylamine for tandem mass spectrometric structure analysis of enzymatically and acidically depolymerized methyl cellulose.

Momcilovic D, Schagerlöf H, Röme D, Jörntén-Karlsson M, Karlsson KE, Wittgren B, Tjerneld F, Wahlund KG, Brinkmalm G.

Anal Chem. 2005 May 1;77(9):2948-59.

PMID:
15859615
12.

Use of liquid chromatography-diode-array detection and mass spectrometry for rapid product identification in biotechnological synthesis of a hydroxyprogesterone.

Lindholm J, Westerlund D, Karlsson KE, Caldwell K, Fornstedt T.

J Chromatogr A. 2003 Apr 11;992(1-2):85-100.

PMID:
12735465
13.

Polar organic phase liquid chromatography with packed capillary columns using a vancomycin chiral stationary phase

Svensson LA, Donnecke J, Karlsson KE, Karlsson A, Vessman J.

Chirality. 2000 Aug;12(8):606-13.

PMID:
10897097
14.

[The "green keyhole" project for public health. The effect of society's impact on health is difficult to measure].

Lindholm L, Janlert U, Karlsson KE, Waldau S, Weinehall L.

Lakartidningen. 1997 May 14;94(20):1905-7. Swedish. No abstract available.

PMID:
9190481
15.

Serpin conformational change in ovalbumin. Enhanced reactive center loop insertion through hinge region mutations.

Huntington JA, Fan B, Karlsson KE, Deinum J, Lawrence DA, Gettins PG.

Biochemistry. 1997 May 6;36(18):5432-40.

PMID:
9154925
16.

Characterisation of the complex of plasminogen activator inhibitor type 1 with tissue-type plasminogen activator by mass spectrometry and size-exclusion chromatography.

Strömqvist M, Karlsson KE, Björquist P, Andersson JO, Byström M, Hansson L, Johansson T, Deinum J.

Biochim Biophys Acta. 1996 Jun 7;1295(1):103-9.

PMID:
8679667
17.

Identification of a new by-product detected in metoprolol tartrate.

Erickson M, Karlsson KE, Lamm B, Larsson S, Svensson LA, Vessman J.

J Pharm Biomed Anal. 1995 Apr;13(4-5):567-74.

PMID:
9696571
18.

A metabolic route of omeprazole involving conjugation with glutathione identified in the rat.

Weidolf L, Karlsson KE, Nilsson I.

Drug Metab Dispos. 1992 Mar-Apr;20(2):262-7.

PMID:
1352219
19.

Separation efficiency of slurry-packed liquid chromatography microcolumns with very small inner diameters.

Karlsson KE, Novotny M.

Anal Chem. 1988 Sep 1;60(17):1662-5. No abstract available.

PMID:
3232810
20.

Direct derivatization of drugs in untreated biological samples for gas chromatographic analysis.

Vessman J, Karlsson KE, Gyllenhaal O.

J Pharm Biomed Anal. 1986;4(6):825-34.

PMID:
16867563
21.

7-[(Chlorocarbonyl)methoxy]-4-methylcoumarin: a novel fluorescent reagent for the precolumn derivatization of hydroxy compounds in liquid chromatography.

Karlsson KE, Wiesler D, Alasandro M, Novotny M.

Anal Chem. 1985 Jan;57(1):229-34. No abstract available.

PMID:
3985337
22.

New biochemical separations using precolumn derivatization and microcolumn liquid chromatography.

Novotny M, Karlsson KE, Konishi M, Alasandro M.

J Chromatogr. 1984 May 25;292(1):159-67.

PMID:
6547449
24.

A comparison of three injectable corticosteroids for the treatment of patients with seasonal hay fever.

Ohlander BO, Hansson RE, Karlsson KE.

J Int Med Res. 1980;8(1):63-9.

PMID:
7358206
25.

A selected ion monitoring method for the determination of pethidine and norpethidine in plasma. Comparison with a gas chromatographic method using electron capture detection.

Lindberg C, Berg M, Boréus LO, Hartvig P, Karlsson KE, Palmér L, Thörnblad AM.

Biomed Mass Spectrom. 1978 Sep;5(9):540-3.

PMID:
708856
26.

Determination of pethidinic acid and norpethidinic acid in urine by mass fragmentography after extractive alkylation.

Lindberg C, Karlsson KE, Hartvig P.

Acta Pharm Suec. 1978;15(5):327-36. No abstract available.

PMID:
747092
27.
28.
29.

A computer program for an open two compartment system distinguishing three models.

Cederblad G, Floderus A, Karlsson KE.

Acta Physiol Scand. 1976 Apr;96(4):471-7.

PMID:
1274622
30.

Electron capture gas chromatography of nanogram amounts of tertiary amines as trichloroethyl carbamates.

Hartvig P, Ahnfelt NO, Karlsson KE.

Acta Pharm Suec. 1976;13(2):181-9. No abstract available.

PMID:
937011
31.

Gene for improved nutritional value in barley seed protein.

Munck L, Karlsson KE, Hagberg A, Eggum BO.

Science. 1970 May 22;168(3934):985-7.

PMID:
4909621

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