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Items: 1 to 50 of 64

1.

Ludwig Boltzmann Cluster Oncology (LBC ONC): first 10 years and future perspectives.

Valent P, Hadzijusufovic E, Grunt T, Karlic H, Peter B, Herrmann H, Eisenwort G, Hoermann G, Schulenburg A, Willmann M, Hubmann R, Shehata M, Selzer E, Gleixner KV, Rülicke T, Sperr WR, Marian B, Pfeilstöcker M, Pehamberger H, Keil F, Jäger U, Zielinski C.

Wien Klin Wochenschr. 2018 Sep;130(17-18):517-529. doi: 10.1007/s00508-018-1355-7. Epub 2018 Jul 13. Review.

2.

Statin and Bisphosphonate Induce Starvation in Fast-Growing Cancer Cell Lines.

Karlic H, Haider F, Thaler R, Spitzer S, Klaushofer K, Varga F.

Int J Mol Sci. 2017 Sep 15;18(9). pii: E1982. doi: 10.3390/ijms18091982.

3.

Anabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate.

Thaler R, Maurizi A, Roschger P, Sturmlechner I, Khani F, Spitzer S, Rumpler M, Zwerina J, Karlic H, Dudakovic A, Klaushofer K, Teti A, Rucci N, Varga F, van Wijnen AJ.

J Biol Chem. 2016 Mar 25;291(13):6754-71. doi: 10.1074/jbc.M115.678235. Epub 2016 Jan 12.

4.

Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells.

Karlic H, Thaler R, Gerner C, Grunt T, Proestling K, Haider F, Varga F.

Cancer Genet. 2015 May;208(5):241-52. doi: 10.1016/j.cancergen.2015.03.008. Epub 2015 Mar 18.

5.

The role of epigenetics in the regulation of apoptosis in myelodysplastic syndromes and acute myeloid leukemia.

Karlic H, Herrmann H, Varga F, Thaler R, Reitermaier R, Spitzer S, Ghanim V, Blatt K, Sperr WR, Valent P, Pfeilstöcker M.

Crit Rev Oncol Hematol. 2014 Apr;90(1):1-16. doi: 10.1016/j.critrevonc.2013.10.003. Epub 2013 Oct 12. Review.

PMID:
24183913
6.

Ibandronate increases the expression of the pro-apoptotic gene FAS by epigenetic mechanisms in tumor cells.

Thaler R, Spitzer S, Karlic H, Berger C, Klaushofer K, Varga F.

Biochem Pharmacol. 2013 Jan 15;85(2):173-85. doi: 10.1016/j.bcp.2012.10.016. Epub 2012 Oct 24.

7.

Epigenetics and the power of art.

Karlic H, Baurek P.

Clin Epigenetics. 2011 Aug;2(2):279-82. doi: 10.1007/s13148-011-0033-7. Epub 2011 Apr 15.

8.

Epigenetic mechanisms in anti-cancer actions of bioactive food components--the implications in cancer prevention.

Stefanska B, Karlic H, Varga F, Fabianowska-Majewska K, Haslberger A.

Br J Pharmacol. 2012 Sep;167(2):279-97. doi: 10.1111/j.1476-5381.2012.02002.x. Review.

9.

DMSO is a strong inducer of DNA hydroxymethylation in pre-osteoblastic MC3T3-E1 cells.

Thaler R, Spitzer S, Karlic H, Klaushofer K, Varga F.

Epigenetics. 2012 Jun 1;7(6):635-51. doi: 10.4161/epi.20163. Epub 2012 Jun 1.

10.

5-azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS-demethylation and FAS re-expression, and synergism with FAS-ligand.

Ghanim V, Herrmann H, Heller G, Peter B, Hadzijusufovic E, Blatt K, Schuch K, Cerny-Reiterer S, Mirkina I, Karlic H, Pickl WF, Zöchbauer-Müller S, Valent P.

Blood. 2012 May 3;119(18):4242-52. doi: 10.1182/blood-2011-09-382770. Epub 2012 Mar 21.

PMID:
22438247
11.

Determination of surface concentrations of individual molecule-layers used in nanoscale biosensors by in situ ATR-FTIR spectroscopy.

Punzet M, Baurecht D, Varga F, Karlic H, Heitzinger C.

Nanoscale. 2012 Apr 7;4(7):2431-8. doi: 10.1039/c2nr12038k. Epub 2012 Mar 8.

PMID:
22399200
12.

Blockade of fatty acid synthase induces ubiquitination and degradation of phosphoinositide-3-kinase signaling proteins in ovarian cancer.

Tomek K, Wagner R, Varga F, Singer CF, Karlic H, Grunt TW.

Mol Cancer Res. 2011 Dec;9(12):1767-79. doi: 10.1158/1541-7786.MCR-10-0467. Epub 2011 Oct 4.

13.

Functional aspects of cytidine-guanosine dinucleotides and their locations in genes.

Varga F, Karlic H, Thaler R, Klaushofer K.

Biomol Concepts. 2011 Oct 1;2(5):391-405. doi: 10.1515/BMC.2011.036.

PMID:
25962044
14.

Impact of vitamin D metabolism on clinical epigenetics.

Karlic H, Varga F.

Clin Epigenetics. 2011 Apr;2(1):55-61. doi: 10.1007/s13148-011-0021-y. Epub 2011 Feb 8.

15.

Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1, and epigenetic DNA methylation.

Thaler R, Agsten M, Spitzer S, Paschalis EP, Karlic H, Klaushofer K, Varga F.

J Biol Chem. 2011 Feb 18;286(7):5578-88. doi: 10.1074/jbc.M110.166181. Epub 2010 Dec 9.

16.

Cancer patients' perception of information exchange between hospital-based doctors and their general practitioners.

Spiegel W, Zidek T, Karlic H, Maier M, Vutuc C, Isak K, Micksche M.

J Eval Clin Pract. 2010 Dec;16(6):1309-13. doi: 10.1111/j.1365-2753.2009.01333.x. Epub 2010 Aug 24.

PMID:
20738477
17.

[Tumor stem cell research - basis and challenge for diagnosis and therapy].

Karlic H, Herrmann H, Schulenburg A, Grunt TW, Laffer S, Mirkina I, Hubmann R, Shehata M, Marian B, Selzer E, Pfeilstöcker M, Pittermann E, Jäger U, Pehamberger H, Zielinski C, Valent P.

Wien Klin Wochenschr. 2010 Jul;122(13-14):423-36. doi: 10.1007/s00508-010-1408-z. Epub 2010 Jul 22. Review. German.

PMID:
20645015
18.

Extra-cellular matrix suppresses expression of the apoptosis mediator Fas by epigenetic DNA methylation.

Thaler R, Karlic H, Spitzer S, Klaushofer K, Varga F.

Apoptosis. 2010 Jun;15(6):728-37. doi: 10.1007/s10495-010-0462-3.

PMID:
20428952
19.

Neoplastic stem cells: current concepts and clinical perspectives.

Schulenburg A, Brämswig K, Herrmann H, Karlic H, Mirkina I, Hubmann R, Laffer S, Marian B, Shehata M, Krepler C, Pehamberger H, Grunt T, Jäger U, Zielinski CC, Valent P.

Crit Rev Oncol Hematol. 2010 Nov;76(2):79-98. doi: 10.1016/j.critrevonc.2010.01.001. Epub 2010 Feb 25. Review.

PMID:
20185329
20.

Osteocalcin attenuates T3- and increases vitamin D3-induced expression of MMP-13 in mouse osteoblasts.

Varga F, Rumpler M, Spitzer S, Karlic H, Klaushofer K.

Endocr J. 2009;56(3):441-50. Epub 2009 Feb 18.

21.

Relationship between carnitine, fatty acids and insulin resistance.

Lohninger A, Radler U, Jinniate S, Lohninger S, Karlic H, Lechner S, Mascher D, Tammaa A, Salzer H.

Gynakol Geburtshilfliche Rundsch. 2009;49(4):230-5. doi: 10.1159/000301075. Epub 2010 May 19.

PMID:
20530934
22.

Vegetarian diet affects genes of oxidative metabolism and collagen synthesis.

Karlic H, Schuster D, Varga F, Klindert G, Lapin A, Haslberger A, Handschur M.

Ann Nutr Metab. 2008;53(1):29-32. doi: 10.1159/000152871. Epub 2008 Sep 5.

PMID:
18772587
23.

Epigenetic regulation of human buccal mucosa mitochondrial superoxide dismutase gene expression by diet.

Thaler R, Karlic H, Rust P, Haslberger AG.

Br J Nutr. 2009 Mar;101(5):743-9. doi: 10.1017/S0007114508047685. Epub 2008 Aug 7.

PMID:
18684339
24.

Breaking bad news to cancer patients: survey and analysis.

Spiegel W, Zidek T, Maier M, Vutuc C, Isak K, Karlic H, Micksche M.

Psychooncology. 2009 Feb;18(2):179-86. doi: 10.1002/pon.1383.

PMID:
18677710
25.

Lysyl oxidase (LOX) mRNA expression and genes of the differentiated osteoblastic phenotype are upregulated in human osteosarcoma cells by suramin.

Buchinger B, Spitzer S, Karlic H, Klaushofer K, Varga F.

Cancer Lett. 2008 Jun 28;265(1):45-54. doi: 10.1016/j.canlet.2008.02.008. Epub 2008 Apr 18.

PMID:
18374478
26.

Preanalytic removal of human DNA eliminates false signals in general 16S rDNA PCR monitoring of bacterial pathogens in blood.

Handschur M, Karlic H, Hertel C, Pfeilstöcker M, Haslberger AG.

Comp Immunol Microbiol Infect Dis. 2009 May;32(3):207-19. doi: 10.1016/j.cimid.2007.10.005. Epub 2008 Feb 7.

PMID:
18261798
27.

Myelodysplastic syndromes, aging, and age: correlations, common mechanisms, and clinical implications.

Pfeilstöcker M, Karlic H, Nösslinger T, Sperr W, Stauder R, Krieger O, Valent P.

Leuk Lymphoma. 2007 Oct;48(10):1900-9. Review.

PMID:
17917959
28.

Imatinib mesylate (IM)-induced growth inhibition is associated with production of spliced osteocalcin-mRNA in cell lines.

Wihlidal P, Karlic H, Pfeilstöcker M, Klaushofer K, Varga F.

Leuk Res. 2008 Mar;32(3):437-43. Epub 2007 Sep 5.

PMID:
17822760
29.

Recursive causality in evolution: a model for epigenetic mechanisms in cancer development.

Haslberger A, Varga F, Karlic H.

Med Hypotheses. 2006;67(6):1448-54. Epub 2006 Jul 17.

PMID:
16844314
30.

Does mRNA level of microsomal carnitine palmitoyltransferase predict yield of peripheral blood stem cell apheresis?

Fillitz M, Karlic H, Tüchler H, Zeibig J, Spiegel W, Wihlidal P, Varga F, Pittermann E, Pfeilstöcker M.

Ann Hematol. 2006 Jun;85(6):386-93. Epub 2006 Mar 24.

PMID:
16557380
31.

Expression and functional significance of osteocalcin splicing in disease progression of hematological malignancies.

Wihlidal P, Varga F, Pfeilstöcker M, Karlic H.

Leuk Res. 2006 Oct;30(10):1241-8. Epub 2006 Jan 4.

PMID:
16387359
32.

Effects of doxorubicin-containing chemotherapy and a combination with L-carnitine on oxidative metabolism in patients with non-Hodgkin lymphoma.

Waldner R, Laschan C, Lohninger A, Gessner M, Tüchler H, Huemer M, Spiegel W, Karlic H.

J Cancer Res Clin Oncol. 2006 Feb;132(2):121-8. Epub 2005 Nov 8.

PMID:
16283381
33.

Do blood cells mimic gene expression profile alterations known to occur in muscular adaptation to endurance training?

Zeibig J, Karlic H, Lohninger A, Damsgaard R, Smekal G.

Eur J Appl Physiol. 2005 Sep;95(1):96-104. Epub 2005 Apr 7. Erratum in: Eur J Appl Physiol. 2005 Sep;95(1):105. Dumsgaard, R [corrected to Damsgaard, R].

PMID:
15815935
34.

Supplementation of L-carnitine in athletes: does it make sense?

Karlic H, Lohninger A.

Nutrition. 2004 Jul-Aug;20(7-8):709-15. Review.

PMID:
15212755
35.

Downregulation of carnitine acyltransferases and organic cation transporter OCTN2 in mononuclear cells in healthy elderly and patients with myelodysplastic syndromes.

Karlic H, Lohninger A, Laschan C, Lapin A, Böhmer F, Huemer M, Guthann E, Rappold E, Pfeilstöcker M.

J Mol Med (Berl). 2003 Jul;81(7):435-42. Epub 2003 Jun 12.

PMID:
12802501
36.

Assessment of growth and differentiation processes in myelodysplastic syndromes by PCR analysis of Galpha16 and 5'-lipoxygenase.

Pfeilstöcker M, Karlic H, Nösslinger T, Tüchler H, Lohninger A, Pittermann E.

Ann Hematol. 2002 Nov;81(11):632-40. Epub 2002 Oct 23.

PMID:
12454701
37.
38.

Dietary l-carnitine stimulates carnitine acyltransferases in the liver of aged rats.

Karlic H, Lohninger S, Koeck T, Lohninger A.

J Histochem Cytochem. 2002 Feb;50(2):205-12.

PMID:
11799139
39.
40.

Expression of insulin-like growth factor-I (IGF-I) in aneurysmal bone cyst.

Leithner A, Lang S, Windhager R, Leithner K, Karlic H, Kotz R, Haas OA.

Mod Pathol. 2001 Nov;14(11):1100-4.

41.
42.

Hematopoietic recovery after IEV chemotherapy for malignant lymphoma followed by different cytokines can be monitored by analysis of Galpha 16 and CD34.

Pfeilstöcker M, Karlic H, Salamon J, Mühlberger H, Pavlova B, Strobl H, Pittermann E, Heinz R.

Am J Hematol. 2000 Jul;64(3):156-60.

43.

The hemoregulatory peptide pEEDCK may inhibit stem cell proliferation via hydropathic binding to antisense sequence motifs in interleukin-11 and other growth factors.

Paukovits JB, Rutter R, Ganglberger E, Karlic HI, Marian B, Paukovits WR.

Mol Pharmacol. 1999 Oct;56(4):665-74.

PMID:
10496948
44.

In vivo and in vitro effects of cytokines and the hemoregulatory peptide dimer (pEEDCK)2 (pyroGlu-Glu-Asp-Cys-Lys)2 on G alpha16-positive hematopoiesis.

Pfeilstöcker M, Karlic H, Paukovits J, Anzenberger G, Louda N, Salamon J, Mühlberger H, Strobl H, Pittermann E, Heinz R.

Leukemia. 1999 Apr;13(4):590-4.

45.

Monitoring of hematopoietic recovery after autologous stem cell transplantation by analysis of G alpha 16 mRNA and CD34 surface glycoprotein.

Pfeilstöcker M, Karlic H, Salamon J, Mühlberger H, Pavlova B, Selim U, Strobl H, Pittermann E, Heinz R.

Ann Hematol. 1998 Mar-Apr;76(3-4):153-8.

PMID:
9619733
46.

Association of human T-cell leukemia virus and myelodysplastic syndrome in a central European population.

Karlic H, Möstl M, Mucke H, Pavlova B, Pfeilstöcker M, Heinz R.

Cancer Res. 1997 Nov 1;57(21):4718-21.

47.

Expression of G alpha 16, a G-protein alpha subunit specific for hematopoiesis in acute leukemia.

Pfeilstöcker M, Karlic H, Salamon J, Krömer E, Mühlberger H, Pavlova B, Selim U, Tüchler H, Fritsch G, Kneissl S, Heinz R, Pitterman E, Paukovits MR.

Leukemia. 1996 Jul;10(7):1117-21.

PMID:
8683989
48.

Cytogenetic findings in 175 patients indicate that items of the Kiel classification should not be disregarded in the REAL classification of lymphoid neoplasms.

Nowotny H, Karlic H, Grüner H, Hirsch J, Vesely M, Nader A, Heinz R.

Ann Hematol. 1996 May;72(5):291-301.

PMID:
8645741
49.

Variant forms of Philadelphia translocation in two patients with chronic myeloid leukemia.

Valent A, Zámecníková A, Karlic H, Nowotny H, Krizan P.

Neoplasma. 1996;43(4):239-44.

PMID:
8931748
50.

FMS hemizygosity in myeloid dysplasia and acute myeloid leukemia with chromosomal aberration del(5)(q) demonstrated by polymerase chain reaction.

Pfeilstöcker M, Grill R, Koller E, Krieger O, Pittermann E, Karlic H.

J Mol Med (Berl). 1995 Aug;73(8):403-7.

PMID:
8528742

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