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Items: 1 to 50 of 186

1.

Consistency in Adults' Self-Reported Lifetime Use of Illicit Drugs: A Follow-Up Study Over 13 Years.

Jensen HAR, Karjalainen K, Juel K, Ekholm O.

J Stud Alcohol Drugs. 2018 May;79(3):490-494.

PMID:
29885158
2.

Outcomes of primary anal sphincter repair after obstetric injury and evaluation of a novel three-choice assessment.

Kuismanen K, Nieminen K, Karjalainen K, Lehto K, Uotila J.

Tech Coloproctol. 2018 Mar;22(3):209-214. doi: 10.1007/s10151-018-1770-9. Epub 2018 Mar 15.

3.

The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma.

Soncin I, Sheng J, Chen Q, Foo S, Duan K, Lum J, Poidinger M, Zolezzi F, Karjalainen K, Ruedl C.

Nat Commun. 2018 Feb 8;9(1):582. doi: 10.1038/s41467-018-02834-8.

5.

Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates.

Staquicini DI, D'Angelo S, Ferrara F, Karjalainen K, Sharma G, Smith TL, Tarleton CA, Jaalouk DE, Kuniyasu A, Baze WB, Chaffee BK, Hanley PW, Barnhart KF, Koivunen E, Marchiò S, Sidman RL, Cortes JE, Kantarjian HM, Arap W, Pasqualini R.

Pharmacogenomics J. 2018 May 22;18(3):436-443. doi: 10.1038/tpj.2017.46. Epub 2017 Dec 5.

PMID:
29205207
6.

A Discrete Subset of Monocyte-Derived Cells among Typical Conventional Type 2 Dendritic Cells Can Efficiently Cross-Present.

Sheng J, Chen Q, Soncin I, Ng SL, Karjalainen K, Ruedl C.

Cell Rep. 2017 Oct 31;21(5):1203-1214. doi: 10.1016/j.celrep.2017.10.024.

7.

Social determinants of drug-related mortality in a general population.

Rönkä S, Karjalainen K, Martikainen P, Mäkelä P.

Drug Alcohol Depend. 2017 Dec 1;181:37-43. doi: 10.1016/j.drugalcdep.2017.09.005. Epub 2017 Oct 4.

PMID:
29032023
8.

Long-Lived Innate IL-17-Producing γ/δ T Cells Modulate Antimicrobial Epithelial Host Defense in the Colon.

Muzaki ARBM, Soncin I, Setiagani YA, Sheng J, Tetlak P, Karjalainen K, Ruedl C.

J Immunol. 2017 Nov 15;199(10):3691-3699. doi: 10.4049/jimmunol.1701053. Epub 2017 Oct 13.

PMID:
29030488
9.

Illicit drug use is increasing among non-medical users of prescription drugs-Results from population-based surveys 2002-2014.

Karjalainen K, Lintonen T, Hakkarainen P.

Drug Alcohol Depend. 2017 Sep 1;178:430-434. doi: 10.1016/j.drugalcdep.2017.05.041. Epub 2017 Jul 4.

PMID:
28710967
10.

Measuring Concurrent Polydrug Use in General Populations: A Critical Assessment.

Karjalainen K, Kuussaari K, Kataja K, Tigerstedt C, Hakkarainen P.

Eur Addict Res. 2017;23(3):163-169. doi: 10.1159/000477802. Epub 2017 Jun 23.

PMID:
28641293
11.

Tissue-Resident CD169(+) Macrophages Form a Crucial Front Line against Plasmodium Infection.

Gupta P, Lai SM, Sheng J, Tetlak P, Balachander A, Claser C, Renia L, Karjalainen K, Ruedl C.

Cell Rep. 2016 Aug 9;16(6):1749-1761. doi: 10.1016/j.celrep.2016.07.010. Epub 2016 Jul 28.

12.

Fetal HSCs versus EMP2s.

Sheng J, Ruedl C, Karjalainen K.

Immunity. 2015 Dec 15;43(6):1025. doi: 10.1016/j.immuni.2015.11.023. No abstract available.

13.

Most Tissue-Resident Macrophages Except Microglia Are Derived from Fetal Hematopoietic Stem Cells.

Sheng J, Ruedl C, Karjalainen K.

Immunity. 2015 Aug 18;43(2):382-93. doi: 10.1016/j.immuni.2015.07.016.

14.

The use of psychoactive prescription drugs among DUI suspects.

Karjalainen K, Haukka J, Lintonen T, Joukamaa M, Lillsunde P.

Drug Alcohol Depend. 2015 Oct 1;155:215-21. doi: 10.1016/j.drugalcdep.2015.07.1195. Epub 2015 Aug 8.

PMID:
26282109
15.

Intestinal CD103(+)CD11b(-) dendritic cells restrain colitis via IFN-γ-induced anti-inflammatory response in epithelial cells.

Muzaki AR, Tetlak P, Sheng J, Loh SC, Setiagani YA, Poidinger M, Zolezzi F, Karjalainen K, Ruedl C.

Mucosal Immunol. 2016 Mar;9(2):336-51. doi: 10.1038/mi.2015.64. Epub 2015 Jul 15.

16.

Smoking, alcohol use, socioeconomic background and oral health among young Finnish adults.

Tanner T, Päkkilä J, Karjalainen K, Kämppi A, Järvelin MR, Patinen P, Tjäderhane L, Anttonen V.

Community Dent Oral Epidemiol. 2015 Oct;43(5):406-14. doi: 10.1111/cdoe.12163. Epub 2015 Apr 24.

PMID:
25912378
17.

Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens.

Karjalainen K, Jaalouk DE, Bueso-Ramos C, Bover L, Sun Y, Kuniyasu A, Driessen WH, Cardó-Vila M, Rietz C, Zurita AJ, O'Brien S, Kantarjian HM, Cortes JE, Calin GA, Koivunen E, Arap W, Pasqualini R.

Clin Cancer Res. 2015 Jul 1;21(13):3041-51. doi: 10.1158/1078-0432.CCR-13-3059. Epub 2015 Mar 16.

18.

Growing medicine: small-scale cannabis cultivation for medical purposes in six different countries.

Hakkarainen P, Frank VA, Barratt MJ, Dahl HV, Decorte T, Karjalainen K, Lenton S, Potter G, Werse B.

Int J Drug Policy. 2015 Mar;26(3):250-6. doi: 10.1016/j.drugpo.2014.07.005. Epub 2014 Jul 21.

PMID:
25123694
19.

Personally prescribed psychoactive drugs in overdose deaths among drug abusers: a retrospective register study.

Rönkä S, Karjalainen K, Vuori E, Mäkelä P.

Drug Alcohol Rev. 2015 Jan;34(1):82-9. doi: 10.1111/dar.12182. Epub 2014 Aug 8.

PMID:
25110189
20.

Transient ablation of alveolar macrophages leads to massive pathology of influenza infection without affecting cellular adaptive immunity.

Purnama C, Ng SL, Tetlak P, Setiagani YA, Kandasamy M, Baalasubramanian S, Karjalainen K, Ruedl C.

Eur J Immunol. 2014 Jul;44(7):2003-12. doi: 10.1002/eji.201344359. Epub 2014 Apr 29.

21.

The arrest of drivers under the influence as a predictor of subsequent social disadvantage and death.

Karjalainen K, Haukka J, Lillsunde P, Lintonen T, Mäkelä P.

Drug Alcohol Depend. 2014 Apr 1;137:114-20. doi: 10.1016/j.drugalcdep.2014.01.018. Epub 2014 Feb 4.

PMID:
24566278
22.

Design, development, and validation of a high-throughput drug-screening assay for targeting of human leukemia.

Karjalainen K, Pasqualini R, Cortes JE, Kornblau SM, Lichtiger B, O'Brien S, Kantarjian HM, Sidman RL, Arap W, Koivunen E.

Cancer. 2014 Feb 15;120(4):589-602. doi: 10.1002/cncr.28419. Epub 2013 Oct 25.

23.

The selection of mature B cells is critically dependent on the expression level of the co-receptor CD19.

von Muenchow L, Engdahl C, Karjalainen K, Rolink AG.

Immunol Lett. 2014 Aug;160(2):113-9. doi: 10.1016/j.imlet.2014.01.011. Epub 2014 Jan 25.

PMID:
24472602
24.

An epigenetic profile of early T-cell development from multipotent progenitors to committed T-cell descendants.

Vigano MA, Ivanek R, Balwierz P, Berninger P, van Nimwegen E, Karjalainen K, Rolink A.

Eur J Immunol. 2014 Apr;44(4):1181-93. doi: 10.1002/eji.201344022. Epub 2014 Feb 1.

25.

A prospective, randomized study comparing minilaparotomy and laparoscopic cholecystectomy as a day-surgery procedure: 5-year outcome.

Aspinen S, Harju J, Juvonen P, Karjalainen K, Kokki H, Paajanen H, Eskelinen M.

Surg Endosc. 2014 Mar;28(3):827-32. doi: 10.1007/s00464-013-3214-y. Epub 2013 Oct 3.

PMID:
24196543
26.

Prevalence and polarization of dental caries among young, healthy adults: Cross-sectional epidemiological study.

Tanner T, Kämppi A, Päkkilä J, Patinen P, Rosberg J, Karjalainen K, Järvelin MR, Tjäderhane L, Anttonen V.

Acta Odontol Scand. 2013 Nov;71(6):1436-42. doi: 10.3109/00016357.2013.767932. Epub 2013 Apr 30.

PMID:
23627898
27.

Deficiency in IL-17-committed Vγ4(+) γδ T cells in a spontaneous Sox13-mutant CD45.1(+) congenic mouse substrain provides protection from dermatitis.

Gray EE, Ramírez-Valle F, Xu Y, Wu S, Wu Z, Karjalainen KE, Cyster JG.

Nat Immunol. 2013 Jun;14(6):584-92. doi: 10.1038/ni.2585. Epub 2013 Apr 28.

28.

Mental disorders associated with driving under the influence of alcohol and/or drugs: a register-based study.

Karjalainen K, Lintonen T, Joukamaa M, Lillsunde P.

Eur Addict Res. 2013;19(3):113-20. doi: 10.1159/000342569. Epub 2012 Nov 6.

29.

[Psychoactive drugs and accident risk in road traffic].

Lillsunde P, Langel K, Blencowe T, Kivioja A, Karjalainen K, Lehtonen L.

Duodecim. 2012;128(18):1877-86. Review. Finnish.

PMID:
23088001
30.

Prevalence of the primary LHON mutations in Northern Finland associated with bilateral optic atrophy and tobacco-alcohol amblyopia.

Korkiamäki P, Kervinen M, Karjalainen K, Majamaa K, Uusimaa J, Remes AM.

Acta Ophthalmol. 2013 Nov;91(7):630-4. doi: 10.1111/j.1755-3768.2012.02506.x. Epub 2012 Sep 12.

31.

Cutting edge: Clec9A+ dendritic cells mediate the development of experimental cerebral malaria.

Piva L, Tetlak P, Claser C, Karjalainen K, Renia L, Ruedl C.

J Immunol. 2012 Aug 1;189(3):1128-32. doi: 10.4049/jimmunol.1201171. Epub 2012 Jun 25.

32.

Substance use and social, health and safety-related factors among fatally injured drivers.

Karjalainen K, Blencowe T, Lillsunde P.

Accid Anal Prev. 2012 Mar;45:731-6. doi: 10.1016/j.aap.2011.09.044. Epub 2011 Oct 27.

PMID:
22269564
33.

Evidence for the divergence of innate and adaptive T-cell precursors before commitment to the αβ and γδ lineages.

Kisielow J, Tortola L, Weber J, Karjalainen K, Kopf M.

Blood. 2011 Dec 15;118(25):6591-600. doi: 10.1182/blood-2011-05-352732. Epub 2011 Oct 21.

34.

The association between social determinants and drunken driving: a 15-year register-based study of 81,125 suspects.

Impinen A, Mäkelä P, Karjalainen K, Haukka J, Lintonen T, Lillsunde P, Rahkonen O, Ostamo A.

Alcohol Alcohol. 2011 Nov-Dec;46(6):721-8. doi: 10.1093/alcalc/agr075. Epub 2011 Jun 29.

PMID:
21715414
35.

Socio-economic determinants of drugged driving--a register-based study.

Karjalainen K, Lintonen T, Impinen A, Lillsunde P, Mäkelä P, Rahkonen O, Haukka J, Ostamo A.

Addiction. 2011 Aug;106(8):1448-59. doi: 10.1111/j.1360-0443.2011.03422.x. Epub 2011 May 4.

PMID:
21375644
36.

Induced pluripotent stem cells expressing elevated levels of sox-2, oct-4, and klf-4 are severely reduced in their differentiation from mesodermal to hematopoietic progenitor cells.

Seiler K, Soroush Noghabi M, Karjalainen K, Hummel M, Melchers F, Tsuneto M.

Stem Cells Dev. 2011 Jul;20(7):1131-42. doi: 10.1089/scd.2010.0391. Epub 2011 Feb 24.

PMID:
21348597
37.

Targeting neuropilin-1 in human leukemia and lymphoma.

Karjalainen K, Jaalouk DE, Bueso-Ramos CE, Zurita AJ, Kuniyasu A, Eckhardt BL, Marini FC, Lichtiger B, O'Brien S, Kantarjian HM, Cortes JE, Koivunen E, Arap W, Pasqualini R.

Blood. 2011 Jan 20;117(3):920-7. doi: 10.1182/blood-2010-05-282921. Epub 2010 Nov 9.

38.

Feasibility of minilaparotomy versus laparoscopic cholecystectomy for day surgery: a prospective randomised study.

Harju J, Kokki H, Pääkkönen M, Karjalainen K, Eskelinen M.

Scand J Surg. 2010;99(3):132-6.

PMID:
21044929
39.

High mortality among people suspected of drunk-driving. An 18-year register-based follow-up.

Impinen A, Mäkelä P, Karjalainen K, Rahkonen O, Lintonen T, Lillsunde P, Ostamo A.

Drug Alcohol Depend. 2010 Jul 1;110(1-2):80-4. doi: 10.1016/j.drugalcdep.2010.02.007. Epub 2010 Mar 23.

PMID:
20334987
40.

Mortality and causes of death among drugged drivers.

Karjalainen K, Lintonen T, Impinen A, Mäkelä P, Rahkonen O, Lillsunde P, Ostamo A.

J Epidemiol Community Health. 2010 Jun;64(6):506-12. doi: 10.1136/jech.2009.096990. Epub 2009 Nov 5.

PMID:
19897469
41.

Role of leukemia cell invadosome in extramedullary infiltration.

Stefanidakis M, Karjalainen K, Jaalouk DE, Gahmberg CG, O'Brien S, Pasqualini R, Arap W, Koivunen E.

Blood. 2009 Oct 1;114(14):3008-17. doi: 10.1182/blood-2008-04-148643. Epub 2009 Jul 27.

42.

Post-fracture prescribed calcium and vitamin D supplements alone or, in females, with concomitant anti-osteoporotic drugs is associated with lower mortality in elderly hip fracture patients: a prospective analysis.

Nurmi-Lüthje I, Lüthje P, Kaukonen JP, Kataja M, Kuurne S, Naboulsi H, Karjalainen K.

Drugs Aging. 2009;26(5):409-21. doi: 10.2165/00002512-200926050-00005.

PMID:
19552493
43.

Substance use as a predictor of driving under the influence (DUI) rearrests. a 15-year retrospective study.

Impinen A, Rahkonen O, Karjalainen K, Lintonen T, Lillsunde P, Ostamo A.

Traffic Inj Prev. 2009 Jun;10(3):220-6. doi: 10.1080/15389580902822725.

PMID:
19452362
44.

WITHDRAWN: Biopsychosocial rehabilitation for upper limb repetitive strain injuries in working age adults.

Karjalainen KA, Malmivaara A, van Tulder MW, Roine R, Jauhiainen M, Hurri H, Koes BW.

Cochrane Database Syst Rev. 2009 Jan 21;(1):CD002269. doi: 10.1002/14651858.CD002269.pub2. Review.

PMID:
19160209
45.

Manipulation of immune system via immortal bone marrow stem cells.

Ruedl C, Khameneh HJ, Karjalainen K.

Int Immunol. 2008 Sep;20(9):1211-8. doi: 10.1093/intimm/dxn079. Epub 2008 Jul 21.

PMID:
18644831
46.

SCART scavenger receptors identify a novel subset of adult gammadelta T cells.

Kisielow J, Kopf M, Karjalainen K.

J Immunol. 2008 Aug 1;181(3):1710-6.

47.

WITHDRAWN: Multidisciplinary bio-psycho-social rehabilitation for chronic low-back pain.

Guzmán J, Esmail R, Karjalainen K, Malmivaara A, Irvin E, Bombardier C.

Cochrane Database Syst Rev. 2007 Jul 18;(2):CD000963. Review. Update in: Cochrane Database Syst Rev. 2014;9:CD000963.

PMID:
17636646
48.

Tumor-associated E-cadherin mutations affect binding to the killer cell lectin-like receptor G1 in humans.

Schwartzkopff S, Gründemann C, Schweier O, Rosshart S, Karjalainen KE, Becker KF, Pircher H.

J Immunol. 2007 Jul 15;179(2):1022-9.

49.

Targeting of OSBP-related protein 3 (ORP3) to endoplasmic reticulum and plasma membrane is controlled by multiple determinants.

Lehto M, Hynynen R, Karjalainen K, Kuismanen E, Hyvärinen K, Olkkonen VM.

Exp Cell Res. 2005 Nov 1;310(2):445-62. Epub 2005 Sep 6.

PMID:
16143324
50.

Expression of lymphocyte activation gene 3 (LAG-3) on B cells is induced by T cells.

Kisielow M, Kisielow J, Capoferri-Sollami G, Karjalainen K.

Eur J Immunol. 2005 Jul;35(7):2081-8.

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