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Items: 21

1.

Mapping Variation in Cellular and Transcriptional Response to 1,25-Dihydroxyvitamin D3 in Peripheral Blood Mononuclear Cells.

Kariuki SN, Maranville JC, Baxter SS, Jeong C, Nakagome S, Hrusch CL, Witonsky DB, Sperling AI, Di Rienzo A.

PLoS One. 2016 Jul 25;11(7):e0159779. doi: 10.1371/journal.pone.0159779. eCollection 2016.

PMID:
27454520
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2.

Patterns of Transcriptional Response to 1,25-Dihydroxyvitamin D3 and Bacterial Lipopolysaccharide in Primary Human Monocytes.

Kariuki SN, Blischak JD, Nakagome S, Witonsky DB, Di Rienzo A.

G3 (Bethesda). 2016 May 3;6(5):1345-55. doi: 10.1534/g3.116.028712.

PMID:
26976439
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3.

Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.

Kariuki SN, Ghodke-Puranik Y, Dorschner JM, Chrabot BS, Kelly JA, Tsao BP, Kimberly RP, Alarcón-Riquelme ME, Jacob CO, Criswell LA, Sivils KL, Langefeld CD, Harley JB, Skol AD, Niewold TB.

Genes Immun. 2015 Jan-Feb;16(1):15-23. doi: 10.1038/gene.2014.57. Epub 2014 Oct 23.

PMID:
25338677
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4.

Familial aggregation of high tumor necrosis factor alpha levels in systemic lupus erythematosus.

Mangale D, Kariuki SN, Chrabot BS, Kumabe M, Kelly JA, Harley JB, James JA, Sivils KL, Niewold TB.

Clin Dev Immunol. 2013;2013:267430. doi: 10.1155/2013/267430. Epub 2013 Sep 25.

PMID:
24187561
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5.

Genetic variation near IRF8 is associated with serologic and cytokine profiles in systemic lupus erythematosus and multiple sclerosis.

Chrabot BS, Kariuki SN, Zervou MI, Feng X, Arrington J, Jolly M, Boumpas DT, Reder AT, Goulielmos GN, Niewold TB.

Genes Immun. 2013 Dec;14(8):471-8. doi: 10.1038/gene.2013.42. Epub 2013 Aug 22.

PMID:
23965942
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6.

Gene-expression-guided selection of candidate loci and molecular phenotype analyses enhance genetic discovery in systemic lupus erythematosus.

Koldobskaya Y, Ko K, Kumar AA, Agik S, Arrington J, Kariuki SN, Franek BS, Kumabe M, Utset TO, Jolly M, Skol AD, Niewold TB.

Clin Dev Immunol. 2012;2012:682018. doi: 10.1155/2012/682018. Epub 2012 Jul 25.

PMID:
22988468
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7.

Brief Report: IRF5 systemic lupus erythematosus risk haplotype is associated with asymptomatic serologic autoimmunity and progression to clinical autoimmunity in mothers of children with neonatal lupus.

Cherian TS, Kariuki SN, Franek BS, Buyon JP, Clancy RM, Niewold TB.

Arthritis Rheum. 2012 Oct;64(10):3383-7. doi: 10.1002/art.34571.

PMID:
22674082
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8.

Linkage of type I interferon activity and TNF-alpha levels in serum with sarcoidosis manifestations and ancestry.

Sweiss NJ, Zhang W, Franek BS, Kariuki SN, Moller DR, Patterson KC, Bennett P, Girijala LR, Nair V, Baughman RP, Garcia JG, Niewold TB.

PLoS One. 2011;6(12):e29126. doi: 10.1371/journal.pone.0029126. Epub 2011 Dec 14.

PMID:
22195005
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9.

Osteopontin alleles are associated with clinical characteristics in systemic lupus erythematosus.

Trivedi T, Franek BS, Green SL, Kariuki SN, Kumabe M, Mikolaitis RA, Jolly M, Utset TO, Niewold TB.

J Biomed Biotechnol. 2011;2011:802581. doi: 10.1155/2011/802581. Epub 2011 Oct 26.

PMID:
22131818
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10.

IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus.

Niewold TB, Kelly JA, Kariuki SN, Franek BS, Kumar AA, Kaufman KM, Thomas K, Walker D, Kamp S, Frost JM, Wong AK, Merrill JT, Alarcón-Riquelme ME, Tikly M, Ramsey-Goldman R, Reveille JD, Petri MA, Edberg JC, Kimberly RP, Alarcón GS, Kamen DL, Gilkeson GS, Vyse TJ, James JA, Gaffney PM, Moser KL, Crow MK, Harley JB.

Ann Rheum Dis. 2012 Mar;71(3):463-8. doi: 10.1136/annrheumdis-2011-200463. Epub 2011 Nov 16.

PMID:
22088620
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11.

Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients.

Robinson T, Kariuki SN, Franek BS, Kumabe M, Kumar AA, Badaracco M, Mikolaitis RA, Guerrero G, Utset TO, Drevlow BE, Zaacks LS, Grober JS, Cohen LM, Kirou KA, Crow MK, Jolly M, Niewold TB.

J Immunol. 2011 Aug 1;187(3):1298-303. doi: 10.4049/jimmunol.1100857. Epub 2011 Jun 24.

PMID:
21705624
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12.

Promoter variant of PIK3C3 is associated with autoimmunity against Ro and Sm epitopes in African-American lupus patients.

Kariuki SN, Franek BS, Mikolaitis RA, Utset TO, Jolly M, Skol AD, Niewold TB.

J Biomed Biotechnol. 2010;2010:826434. doi: 10.1155/2010/826434. Epub 2010 Jul 4.

PMID:
20671926
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13.

Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus.

Kariuki SN, Franek BS, Kumar AA, Arrington J, Mikolaitis RA, Utset TO, Jolly M, Crow MK, Skol AD, Niewold TB.

Arthritis Res Ther. 2010;12(4):R151. doi: 10.1186/ar3101. Epub 2010 Jul 26.

PMID:
20659327
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14.

Gene-gene-sex interaction in cytokine gene polymorphisms revealed by serum interferon alpha phenotype in juvenile dermatomyositis.

Niewold TB, Kariuki SN, Morgan GA, Shrestha S, Pachman LM.

J Pediatr. 2010 Oct;157(4):653-7. doi: 10.1016/j.jpeds.2010.04.034.

PMID:
20605164
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15.

African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity.

Lodolce JP, Kolodziej LE, Rhee L, Kariuki SN, Franek BS, McGreal NM, Logsdon MF, Bartulis SJ, Perera MA, Ellis NA, Adams EJ, Hanauer SB, Jolly M, Niewold TB, Boone DL.

J Immunol. 2010 Jun 15;184(12):7001-9. doi: 10.4049/jimmunol.1000324. Epub 2010 May 7.

PMID:
20483768
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16.

Genetic regulation of serum cytokines in systemic lupus erythematosus.

Kariuki SN, Niewold TB.

Transl Res. 2010 Mar;155(3):109-17. doi: 10.1016/j.trsl.2009.08.012. Epub 2009 Sep 25. Review.

PMID:
20171594
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17.

Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients.

Salloum R, Franek BS, Kariuki SN, Rhee L, Mikolaitis RA, Jolly M, Utset TO, Niewold TB.

Arthritis Rheum. 2010 Feb;62(2):553-61. doi: 10.1002/art.27182.

PMID:
20112359
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18.

Elevated serum interferon-alpha activity in juvenile dermatomyositis: associations with disease activity at diagnosis and after thirty-six months of therapy.

Niewold TB, Kariuki SN, Morgan GA, Shrestha S, Pachman LM.

Arthritis Rheum. 2009 Jun;60(6):1815-24. doi: 10.1002/art.24555.

PMID:
19479879
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19.

Age- and gender-specific modulation of serum osteopontin and interferon-alpha by osteopontin genotype in systemic lupus erythematosus.

Kariuki SN, Moore JG, Kirou KA, Crow MK, Utset TO, Niewold TB.

Genes Immun. 2009 Jul;10(5):487-94. doi: 10.1038/gene.2009.15. Epub 2009 Apr 2.

PMID:
19339987
Free PMC Article

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20.

Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo.

Kariuki SN, Kirou KA, MacDermott EJ, Barillas-Arias L, Crow MK, Niewold TB.

J Immunol. 2009 Jan 1;182(1):34-8.

PMID:
19109131
Free PMC Article

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21.

The PTPN22 C1858T polymorphism is associated with skewing of cytokine profiles toward high interferon-alpha activity and low tumor necrosis factor alpha levels in patients with lupus.

Kariuki SN, Crow MK, Niewold TB.

Arthritis Rheum. 2008 Sep;58(9):2818-23. doi: 10.1002/art.23728.

PMID:
18759295
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