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Items: 44


A Case Study on Chronic Hepatitis-C Viral infection Associated with Hepatocellular Carcinoma in a Tertiary Hospital of Bangladesh.

Islam MJ, Saha SK, Das AK, Jahan MS, Pervin S, Karim CF, Kabir S.

Mymensingh Med J. 2019 Oct;28(4):935-939.


Structural dynamics of calmodulin-ryanodine receptor interactions: electron paramagnetic resonance using stereospecific spin labels.

Her C, Thompson AR, Karim CB, Thomas DD.

Sci Rep. 2018 Jul 16;8(1):10681. doi: 10.1038/s41598-018-29064-8.


Calcium-Dependent Structural Dynamics of a Spin-Labeled RyR Peptide Bound to Calmodulin.

Her C, McCaffrey JE, Thomas DD, Karim CB.

Biophys J. 2016 Dec 6;111(11):2387-2394. doi: 10.1016/j.bpj.2016.10.025.


Death Receptor 5 Networks Require Membrane Cholesterol for Proper Structure and Function.

Lewis AK, Valley CC, Peery SL, Brummel B, Braun AR, Karim CB, Sachs JN.

J Mol Biol. 2016 Dec 4;428(24 Pt A):4843-4855. doi: 10.1016/j.jmb.2016.10.001. Epub 2016 Oct 6.


Oxidation increases the strength of the methionine-aromatic interaction.

Lewis AK, Dunleavy KM, Senkow TL, Her C, Horn BT, Jersett MA, Mahling R, McCarthy MR, Perell GT, Valley CC, Karim CB, Gao J, Pomerantz WC, Thomas DD, Cembran A, Hinderliter A, Sachs JN.

Nat Chem Biol. 2016 Oct;12(10):860-6. doi: 10.1038/nchembio.2159. Epub 2016 Aug 22.


Erratum: Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation.

Karim CB, Michel Espinoza-Fonseca L, James ZM, Hanse EA, Gaynes JS, Thomas DD, Kelekar A.

Sci Rep. 2015 Oct 29;5:15872. doi: 10.1038/srep15872. No abstract available.


Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation.

Karim CB, Espinoza-Fonseca LM, James ZM, Hanse EA, Gaynes JS, Thomas DD, Kelekar A.

Sci Rep. 2015 Sep 28;5:14557. doi: 10.1038/srep14557. Erratum in: Sci Rep. 2015;5:15872.


Synthetic phosphopeptides enable quantitation of the content and function of the four phosphorylation states of phospholamban in cardiac muscle.

Ablorh NA, Dong X, James ZM, Xiong Q, Zhang J, Thomas DD, Karim CB.

J Biol Chem. 2014 Oct 17;289(42):29397-405. doi: 10.1074/jbc.M114.556621. Epub 2014 Sep 4.


Open and closed conformations of the isolated transmembrane domain of death receptor 5 support a new model of activation.

Lewis AK, James ZM, McCaffrey JE, Braun AR, Karim CB, Thomas DD, Sachs JN.

Biophys J. 2014 Mar 18;106(6):L21-4. doi: 10.1016/j.bpj.2014.01.044.


A sensitive spectrofluorimetric method for the quantification of melamine residue in milk powder using the Mannich reaction in aqueous solutions.

Rima J, Assaker K, El Omar F, karim Cb.

Talanta. 2013 Nov 15;116:277-82. doi: 10.1016/j.talanta.2013.05.035. Epub 2013 May 24.


Neutralization of prolactin receptor function by monoclonal antibody LFA102, a novel potential therapeutic for the treatment of breast cancer.

Damiano JS, Rendahl KG, Karim C, Embry MG, Ghoddusi M, Holash J, Fanidi A, Abrams TJ, Abraham JA.

Mol Cancer Ther. 2013 Mar;12(3):295-305. doi: 10.1158/1535-7163.MCT-12-0886. Epub 2012 Dec 27.


Protein-protein interactions in calcium transport regulation probed by saturation transfer electron paramagnetic resonance.

James ZM, McCaffrey JE, Torgersen KD, Karim CB, Thomas DD.

Biophys J. 2012 Sep 19;103(6):1370-8. doi: 10.1016/j.bpj.2012.08.032.


Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor 5 networks that are highly organized.

Valley CC, Lewis AK, Mudaliar DJ, Perlmutter JD, Braun AR, Karim CB, Thomas DD, Brody JR, Sachs JN.

J Biol Chem. 2012 Jun 15;287(25):21265-78. doi: 10.1074/jbc.M111.306480. Epub 2012 Apr 10.


Structural and functional dynamics of an integral membrane protein complex modulated by lipid headgroup charge.

Li J, James ZM, Dong X, Karim CB, Thomas DD.

J Mol Biol. 2012 May 18;418(5):379-89. doi: 10.1016/j.jmb.2012.02.011. Epub 2012 Feb 28.


Accurate quantitation of phospholamban phosphorylation by immunoblot.

Ablorh NA, Miller T, Nitu F, Gruber SJ, Karim C, Thomas DD.

Anal Biochem. 2012 Jun 1;425(1):68-75. doi: 10.1016/j.ab.2012.01.028. Epub 2012 Feb 3.


Heart rate monitoring in soccer: interest and limits during competitive match play and training, practical application.

Alexandre D, da Silva CD, Hill-Haas S, Wong del P, Natali AJ, De Lima JR, Bara Filho MG, Marins JJ, Garcia ES, Karim C.

J Strength Cond Res. 2012 Oct;26(10):2890-906. Review.


Functional and physical competition between phospholamban and its mutants provides insight into the molecular mechanism of gene therapy for heart failure.

Lockamy EL, Cornea RL, Karim CB, Thomas DD.

Biochem Biophys Res Commun. 2011 May 13;408(3):388-92. doi: 10.1016/j.bbrc.2011.04.023. Epub 2011 Apr 12.


Lipid-mediated folding/unfolding of phospholamban as a regulatory mechanism for the sarcoplasmic reticulum Ca2+-ATPase.

Gustavsson M, Traaseth NJ, Karim CB, Lockamy EL, Thomas DD, Veglia G.

J Mol Biol. 2011 May 13;408(4):755-65. doi: 10.1016/j.jmb.2011.03.015. Epub 2011 Mar 17.


The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose.

Lowman XH, McDonnell MA, Kosloske A, Odumade OA, Jenness C, Karim CB, Jemmerson R, Kelekar A.

Mol Cell. 2010 Dec 10;40(5):823-33. doi: 10.1016/j.molcel.2010.11.035.


The role of sarcolipin and ATP in the transport of phosphate ion into the sarcoplasmic reticulum.

Becucci L, Guidelli R, Karim CB, Thomas DD, Veglia G.

Biophys J. 2009 Nov 18;97(10):2693-9. doi: 10.1016/j.bpj.2009.08.035.


On the function of pentameric phospholamban: ion channel or storage form?

Becucci L, Cembran A, Karim CB, Thomas DD, Guidelli R, Gao J, Veglia G.

Biophys J. 2009 May 20;96(10):L60-2. doi: 10.1016/j.bpj.2009.03.013.


HIV-1 nucleocapsid protein NCp7 and its RNA stem loop 3 partner: rotational dynamics of spin-labeled RNA stem loop 3.

Xi X, Sun Y, Karim CB, Grigoryants VM, Scholes CP.

Biochemistry. 2008 Sep 23;47(38):10099-110. doi: 10.1021/bi800602e. Epub 2008 Aug 26.


Rotational dynamics of HIV-1 nucleocapsid protein NCp7 as probed by a spin label attached by peptide synthesis.

Zhang Z, Xi X, Scholes CP, Karim CB.

Biopolymers. 2008 Dec;89(12):1125-35. doi: 10.1002/bip.21064.


Controlling the inhibition of the sarcoplasmic Ca2+-ATPase by tuning phospholamban structural dynamics.

Ha KN, Traaseth NJ, Verardi R, Zamoon J, Cembran A, Karim CB, Thomas DD, Veglia G.

J Biol Chem. 2007 Dec 21;282(51):37205-14. Epub 2007 Sep 30.


Spectroscopic validation of the pentameric structure of phospholamban.

Traaseth NJ, Verardi R, Torgersen KD, Karim CB, Thomas DD, Veglia G.

Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14676-81. Epub 2007 Sep 5.


An electrochemical investigation of sarcolipin reconstituted into a mercury-supported lipid bilayer.

Becucci L, Guidelli R, Karim CB, Thomas DD, Veglia G.

Biophys J. 2007 Oct 15;93(8):2678-87. Epub 2007 Jun 22.


Rotational dynamics of phospholamban determined by multifrequency electron paramagnetic resonance.

Nesmelov YE, Karim CB, Song L, Fajer PG, Thomas DD.

Biophys J. 2007 Oct 15;93(8):2805-12. Epub 2007 Jun 15.


Synthesis of TOAC spin-labeled proteins and reconstitution in lipid membranes.

Karim CB, Zhang Z, Thomas DD.

Nat Protoc. 2007;2(1):42-9.


Phosphorylation-dependent conformational switch in spin-labeled phospholamban bound to SERCA.

Karim CB, Zhang Z, Howard EC, Torgersen KD, Thomas DD.

J Mol Biol. 2006 May 12;358(4):1032-40. Epub 2006 Mar 9.


Mapping the interaction surface of a membrane protein: unveiling the conformational switch of phospholamban in calcium pump regulation.

Zamoon J, Nitu F, Karim C, Thomas DD, Veglia G.

Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4747-52. Epub 2005 Mar 21.


Phospholamban structural dynamics in lipid bilayers probed by a spin label rigidly coupled to the peptide backbone.

Karim CB, Kirby TL, Zhang Z, Nesmelov Y, Thomas DD.

Proc Natl Acad Sci U S A. 2004 Oct 5;101(40):14437-42. Epub 2004 Sep 24.


Direct detection of phospholamban and sarcoplasmic reticulum Ca-ATPase interaction in membranes using fluorescence resonance energy transfer.

Mueller B, Karim CB, Negrashov IV, Kutchai H, Thomas DD.

Biochemistry. 2004 Jul 13;43(27):8754-65.


Overexpression, purification, and characterization of recombinant Ca-ATPase regulators for high-resolution solution and solid-state NMR studies.

Buck B, Zamoon J, Kirby TL, DeSilva TM, Karim C, Thomas D, Veglia G.

Protein Expr Purif. 2003 Aug;30(2):253-61.


Structure and function of integral membrane protein domains resolved by peptide-amphiphiles: application to phospholamban.

Lockwood NA, Tu RS, Zhang Z, Tirrell MV, Thomas DD, Karim CB.

Biopolymers. 2003 Jul;69(3):283-92.


Solid-state NMR and rigid body molecular dynamics to determine domain orientations of monomeric phospholamban.

Mascioni A, Karim C, Zamoon J, Thomas DD, Veglia G.

J Am Chem Soc. 2002 Aug 14;124(32):9392-3.


Structure and orientation of sarcolipin in lipid environments.

Mascioni A, Karim C, Barany G, Thomas DD, Veglia G.

Biochemistry. 2002 Jan 15;41(2):475-82.


Role of cysteine residues in structural stability and function of a transmembrane helix bundle.

Karim CB, Paterlini MG, Reddy LG, Hunter GW, Barany G, Thomas DD.

J Biol Chem. 2001 Oct 19;276(42):38814-9. Epub 2001 Jul 26.


Sarcolipin, the shorter homologue of phospholamban, forms oligomeric structures in detergent micelles and in liposomes.

Hellstern S, Pegoraro S, Karim CB, Lustig A, Thomas DD, Moroder L, Engel J.

J Biol Chem. 2001 Aug 17;276(33):30845-52. Epub 2001 Jun 18.


Synthetic null-cysteine phospholamban analogue and the corresponding transmembrane domain inhibit the Ca-ATPase.

Karim CB, Marquardt CG, Stamm JD, Barany G, Thomas DD.

Biochemistry. 2000 Sep 5;39(35):10892-7.


Direct spectroscopic detection of molecular dynamics and interactions of the calcium pump and phospholamban.

Thomas DD, Reddy LG, Karim CB, Li M, Cornea R, Autry JM, Jones LR, Stamm J.

Ann N Y Acad Sci. 1998 Sep 16;853:186-94. Review.


Cysteine reactivity and oligomeric structures of phospholamban and its mutants.

Karim CB, Stamm JD, Karim J, Jones LR, Thomas DD.

Biochemistry. 1998 Sep 1;37(35):12074-81.


Interaction of glyceraldehyde-3-phosphate dehydrogenase with AMP as studied by means of a spin-labeled analog.

Karim C, Philipp R, Trommer WE, Park JH.

Biol Chem Hoppe Seyler. 1989 Dec;370(12):1245-52.


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