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Items: 1 to 50 of 300

1.

Understanding Subdural Collections in Pediatric Abusive Head Trauma.

Wittschieber D, Karger B, Pfeiffer H, Hahnemann ML.

AJNR Am J Neuroradiol. 2018 Dec 6. doi: 10.3174/ajnr.A5855. [Epub ahead of print] Review.

PMID:
30523144
2.

Multi-Omics Study on the Impact of Cysteine Feed Level on Cell Viability and mAb Production in a CHO Bioprocess.

Ali AS, Raju R, Kshirsagar R, Ivanov AR, Gilbert A, Zang L, Karger BL.

Biotechnol J. 2018 Nov 28:e1800352. doi: 10.1002/biot.201800352. [Epub ahead of print]

PMID:
30485675
3.

Complementary middle-down and intact monoclonal antibody proteoform characterization by capillary zone electrophoresis - mass spectrometry.

Belov AM, Zang L, Sebastiano R, Santos MR, Bush DR, Karger BL, Ivanov AR.

Electrophoresis. 2018 Aug;39(16):2069-2082. doi: 10.1002/elps.201800067. Epub 2018 Jun 5.

4.

Quantitative Proteomic Profiling of the Human Ovary from Early to Mid-Gestation Reveals Protein Expression Dynamics of Oogenesis and Folliculogenesis.

Bothun AM, Gao Y, Takai Y, Ishihara O, Seki H, Karger B, Tilly JL, Woods DC.

Stem Cells Dev. 2018 Jun 1;27(11):723-735. doi: 10.1089/scd.2018.0002. Epub 2018 May 29.

PMID:
29631484
5.

Lipidomics of CHO Cell Bioprocessing: Relation to Cell Growth and Specific Productivity of a Monoclonal Antibody.

Ali AS, Raju R, Ray S, Kshirsagar R, Gilbert A, Zang L, Karger BL.

Biotechnol J. 2018 Oct;13(10):e1700745. doi: 10.1002/biot.201700745. Epub 2018 Mar 26.

PMID:
29521466
6.

Analysis of Proteins, Protein Complexes, and Organellar Proteomes Using Sheathless Capillary Zone Electrophoresis - Native Mass Spectrometry.

Belov AM, Viner R, Santos MR, Horn DM, Bern M, Karger BL, Ivanov AR.

J Am Soc Mass Spectrom. 2017 Dec;28(12):2614-2634. doi: 10.1007/s13361-017-1781-1. Epub 2017 Sep 5.

7.

Host Cell Protein Profiling by Targeted and Untargeted Analysis of Data Independent Acquisition Mass Spectrometry Data with Parallel Reaction Monitoring Verification.

Kreimer S, Gao Y, Ray S, Jin M, Tan Z, Mussa NA, Tao L, Li Z, Ivanov AR, Karger BL.

Anal Chem. 2017 May 16;89(10):5294-5302. doi: 10.1021/acs.analchem.6b04892. Epub 2017 Apr 26.

PMID:
28402653
8.

Binding Site Characterization of AM1336, a Novel Covalent Inverse Agonist at Human Cannabinoid 2 Receptor, Using Mass Spectrometric Analysis.

Mallipeddi S, Kreimer S, Zvonok N, Vemuri K, Karger BL, Ivanov AR, Makriyannis A.

J Proteome Res. 2017 Jul 7;16(7):2419-2428. doi: 10.1021/acs.jproteome.7b00023. Epub 2017 Jun 19.

PMID:
28374590
9.

Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma.

Fulciniti M, Martinez-Lopez J, Senapedis W, Oliva S, Lakshmi Bandi R, Amodio N, Xu Y, Szalat R, Gulla A, Samur MK, Roccaro A, Linares M, Cea M, Baloglu E, Argueta C, Landesman Y, Shacham S, Liu S, Schenone M, Wu SL, Karger B, Prabhala R, Anderson KC, Munshi NC.

Blood. 2017 Apr 20;129(16):2233-2245. doi: 10.1182/blood-2016-06-724831. Epub 2017 Jan 17.

10.

Advanced Precursor Ion Selection Algorithms for Increased Depth of Bottom-Up Proteomic Profiling.

Kreimer S, Belov ME, Danielson WF, Levitsky LI, Gorshkov MV, Karger BL, Ivanov AR.

J Proteome Res. 2016 Oct 7;15(10):3563-3573. Epub 2016 Sep 7.

11.

Combined metabolomics and proteomics reveals hypoxia as a cause of lower productivity on scale-up to a 5000-liter CHO bioprocess.

Gao Y, Ray S, Dai S, Ivanov AR, Abu-Absi NR, Lewis AM, Huang Z, Xing Z, Borys MC, Li ZJ, Karger BL.

Biotechnol J. 2016 Sep;11(9):1190-200. doi: 10.1002/biot.201600030. Epub 2016 Jun 29.

PMID:
27213298
12.

High Resolution CZE-MS Quantitative Characterization of Intact Biopharmaceutical Proteins: Proteoforms of Interferon-β1.

Bush DR, Zang L, Belov AM, Ivanov AR, Karger BL.

Anal Chem. 2016 Jan 19;88(2):1138-46. doi: 10.1021/acs.analchem.5b03218. Epub 2015 Dec 24.

PMID:
26641950
13.

A quantitative proteomic analysis of cellular responses to high glucose media in Chinese hamster ovary cells.

Liu Z, Dai S, Bones J, Ray S, Cha S, Karger BL, Li JJ, Wilson L, Hinckle G, Rossomando A.

Biotechnol Prog. 2015 Jul-Aug;31(4):1026-38. doi: 10.1002/btpr.2090. Epub 2015 Apr 29.

PMID:
25857574
14.

Reply to van de Sandt and Rimmelzwaan: Matching epitope display with functional avidity.

Keskin DB, Reinhold BR, Zhang GL, Ivanov AR, Karger BL, Reinherz EL.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):E2418. doi: 10.1073/pnas.1503931112. Epub 2015 Apr 6. No abstract available. Erratum in: Proc Natl Acad Sci U S A. 2015 May 26;112(21):E2845.

15.

Reply: To PMID 24948499.

Wittschieber D, Karger B, Niederstadt T, Pfeiffer H, Hahnemann ML.

AJNR Am J Neuroradiol. 2015 May;36(5):E37. doi: 10.3174/ajnr.A4327. Epub 2015 Mar 12. No abstract available.

16.

An Integrated Platform for Isolation, Processing, and Mass Spectrometry-based Proteomic Profiling of Rare Cells in Whole Blood.

Li S, Plouffe BD, Belov AM, Ray S, Wang X, Murthy SK, Karger BL, Ivanov AR.

Mol Cell Proteomics. 2015 Jun;14(6):1672-83. doi: 10.1074/mcp.M114.045724. Epub 2015 Mar 9.

17.

Immunological mechanisms of the antitumor effects of supplemental oxygenation.

Hatfield SM, Kjaergaard J, Lukashev D, Schreiber TH, Belikoff B, Abbott R, Sethumadhavan S, Philbrook P, Ko K, Cannici R, Thayer M, Rodig S, Kutok JL, Jackson EK, Karger B, Podack ER, Ohta A, Sitkovsky MV.

Sci Transl Med. 2015 Mar 4;7(277):277ra30. doi: 10.1126/scitranslmed.aaa1260.

18.

Physical detection of influenza A epitopes identifies a stealth subset on human lung epithelium evading natural CD8 immunity.

Keskin DB, Reinhold BB, Zhang GL, Ivanov AR, Karger BL, Reinherz EL.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2151-6. doi: 10.1073/pnas.1423482112. Epub 2015 Feb 2.

19.

Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas.

Olsen L, Campos B, Winther O, Sgroi DC, Karger BL, Brusic V.

BMC Med Genomics. 2014;7 Suppl 3:S2. doi: 10.1186/1755-8794-7-S3-S2. Epub 2014 Dec 8.

20.

Pathway analysis and transcriptomics improve protein identification by shotgun proteomics from samples comprising small number of cells--a benchmarking study.

Sun J, Zhang GL, Li S, Ivanov AR, Fenyo D, Lisacek F, Murthy SK, Karger BL, Brusic V.

BMC Genomics. 2014;15 Suppl 9:S1. doi: 10.1186/1471-2164-15-S9-S1. Epub 2014 Dec 8.

21.

Development of LC-MS methods for quantitation of hepcidin and demonstration of siRNA-mediated hepcidin suppression in serum.

Li S, Nakayama T, Akinc A, Wu SL, Karger BL.

J Pharmacol Toxicol Methods. 2015 Jan-Feb;71:110-9. doi: 10.1016/j.vascn.2014.09.008. Epub 2014 Oct 2.

PMID:
25281793
22.

Imaging of bridging vein thrombosis in infants with abusive head trauma: the "Tadpole Sign".

Hahnemann ML, Kinner S, Schweiger B, Bajanowski T, Karger B, Pfeiffer H, Wittschieber D.

Eur Radiol. 2015 Feb;25(2):299-305. doi: 10.1007/s00330-014-3443-z. Epub 2014 Oct 3.

PMID:
25274619
23.

Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection.

Hatfield SM, Kjaergaard J, Lukashev D, Belikoff B, Schreiber TH, Sethumadhavan S, Abbott R, Philbrook P, Thayer M, Shujia D, Rodig S, Kutok JL, Ren J, Ohta A, Podack ER, Karger B, Jackson EK, Sitkovsky M.

J Mol Med (Berl). 2014 Dec;92(12):1283-92. doi: 10.1007/s00109-014-1189-3. Epub 2014 Aug 15.

24.

Near-zero growth kinetics of Pseudomonas putida deduced from proteomic analysis.

Panikov NS, Mandalakis M, Dai S, Mulcahy LR, Fowle W, Garrett WS, Karger BL.

Environ Microbiol. 2015 Jan;17(1):215-28. doi: 10.1111/1462-2920.12584. Epub 2014 Aug 27.

PMID:
25088710
25.

Subdural hygromas in abusive head trauma: pathogenesis, diagnosis, and forensic implications.

Wittschieber D, Karger B, Niederstadt T, Pfeiffer H, Hahnemann ML.

AJNR Am J Neuroradiol. 2015 Mar;36(3):432-9. doi: 10.3174/ajnr.A3989. Epub 2014 Jun 19. Review.

26.

Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments.

Brazin KN, Mallis RJ, Li C, Keskin DB, Arthanari H, Gao Y, Wu SL, Karger BL, Wagner G, Reinherz EL.

J Biol Chem. 2014 Jul 4;289(27):18880-92. doi: 10.1074/jbc.M114.574996. Epub 2014 May 21. Erratum in: J Biol Chem. 2015 Jan 2;290(1):239.

27.

Comparative proteomic analysis reveals mechanistic insights into Pseudomonas putida F1 growth on benzoate and citrate.

Mandalakis M, Panikov N, Dai S, Ray S, Karger BL.

AMB Express. 2013 Oct 25;3(1):64. doi: 10.1186/2191-0855-3-64.

28.

Human folliculin delays cell cycle progression through late S and G2/M-phases: effect of phosphorylation and tumor associated mutations.

Laviolette LA, Wilson J, Koller J, Neil C, Hulick P, Rejtar T, Karger B, Teh BT, Iliopoulos O.

PLoS One. 2013 Jul 11;8(7):e66775. doi: 10.1371/journal.pone.0066775. Print 2013.

29.

Comparability analysis of anti-CD20 commercial (rituximab) and RNAi-mediated fucosylated antibodies by two LC-MS approaches.

Li C, Rossomando A, Wu SL, Karger BL.

MAbs. 2013 Jul-Aug;5(4):565-75. doi: 10.4161/mabs.24814. Epub 2013 Apr 25.

30.

In-depth characterization of N-linked oligosaccharides using fluoride-mediated negative ion microfluidic chip LC-MS.

Ni W, Bones J, Karger BL.

Anal Chem. 2013 Mar 19;85(6):3127-35. doi: 10.1021/ac3031898. Epub 2013 Feb 27.

31.

Integrated proteomic analysis of major isoaspartyl-containing proteins in the urine of wild type and protein L-isoaspartate O-methyltransferase-deficient mice.

Dai S, Ni W, Patananan AN, Clarke SG, Karger BL, Zhou ZS.

Anal Chem. 2013 Feb 19;85(4):2423-30. doi: 10.1021/ac303428h. Epub 2013 Feb 6.

32.

Complete mapping of a cystine knot and nested disulfides of recombinant human arylsulfatase A by multi-enzyme digestion and LC-MS analysis using CID and ETD.

Ni W, Lin M, Salinas P, Savickas P, Wu SL, Karger BL.

J Am Soc Mass Spectrom. 2013 Jan;24(1):125-33. doi: 10.1007/s13361-012-0510-z. Epub 2012 Dec 4.

33.

Evaluation of exogenous siRNA addition as a metabolic engineering tool for modifying biopharmaceuticals.

Tummala S, Titus M, Wilson L, Wang C, Ciatto C, Thill G, Foster D, Li C, Szabo Z, Guttman A, Bettencourt B, Jayaraman M, Deroot J, Kocisko D, Pollard S, Charisse K, Kuchimanchi S, Hinkle G, Milstein S, Meyers R, Wu SL, Karger BL, Rossomando A.

Biotechnol Prog. 2013 Mar-Apr;29(2):415-24. doi: 10.1002/btpr.1667. Epub 2013 Feb 13.

34.

Reversion of the ErbB malignant phenotype and the DNA damage response.

Runkle EA, Zhang H, Cai Z, Zhu Z, Karger BL, Wu SL, O'Rourke DM, Zhou Z, Wang Q, Greene MI.

Exp Mol Pathol. 2012 Dec;93(3):324-33. doi: 10.1016/j.yexmp.2012.09.007. Epub 2012 Sep 27. Review.

35.

Sialic acid speciation using capillary electrophoresis: optimization of analyte derivatization and separation.

Szabo Z, Bones J, Guttman A, Glick J, Karger BL.

Anal Chem. 2012 Sep 18;84(18):7638-42. doi: 10.1021/ac301840f. Epub 2012 Aug 29.

36.

Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function.

Song X, Li B, Xiao Y, Chen C, Wang Q, Liu Y, Berezov A, Xu C, Gao Y, Li Z, Wu SL, Cai Z, Zhang H, Karger BL, Hancock WW, Wells AD, Zhou Z, Greene MI.

Cell Rep. 2012 Jun 28;1(6):665-75. doi: 10.1016/j.celrep.2012.04.012. Epub 2012 Jun 15.

37.

Ultrasensitive capillary electrophoretic analysis of potentially immunogenic carbohydrate residues in biologics: galactose-α-1,3-galactose containing oligosaccharides.

Szabo Z, Guttman A, Bones J, Shand RL, Meh D, Karger BL.

Mol Pharm. 2012 Jun 4;9(6):1612-9. doi: 10.1021/mp200612n. Epub 2012 May 15.

38.

Suicide with two shots to the head inflicted by a captive-bolt gun.

Fanton L, Karger B.

J Forensic Leg Med. 2012 Feb;19(2):90-3. doi: 10.1016/j.jflm.2011.07.010. Epub 2011 Aug 5.

PMID:
22281217
39.

Integrated proteomic, transcriptomic, and biological network analysis of breast carcinoma reveals molecular features of tumorigenesis and clinical relapse.

Imielinski M, Cha S, Rejtar T, Richardson EA, Karger BL, Sgroi DC.

Mol Cell Proteomics. 2012 Jun;11(6):M111.014910. doi: 10.1074/mcp.M111.014910. Epub 2012 Jan 12.

40.

Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope.

Zhou Z, Du X, Cai Z, Song X, Zhang H, Mizuno T, Suzuki E, Yee MR, Berezov A, Murali R, Wu SL, Karger BL, Greene MI, Wang Q.

J Biol Chem. 2012 Feb 17;287(8):5317-26. doi: 10.1074/jbc.M111.304543. Epub 2011 Dec 14.

41.
42.

Microproteomic analysis of 10,000 laser captured microdissected breast tumor cells using short-range sodium dodecyl sulfate-polyacrylamide gel electrophoresis and porous layer open tubular liquid chromatography tandem mass spectrometry.

Thakur D, Rejtar T, Wang D, Bones J, Cha S, Clodfelder-Miller B, Richardson E, Binns S, Dahiya S, Sgroi D, Karger BL.

J Chromatogr A. 2011 Nov 11;1218(45):8168-74. doi: 10.1016/j.chroma.2011.09.022. Epub 2011 Sep 14.

43.

Discovery of lung cancer biomarkers by profiling the plasma proteome with monoclonal antibody libraries.

Guergova-Kuras M, Kurucz I, Hempel W, Tardieu N, Kádas J, Malderez-Bloes C, Jullien A, Kieffer Y, Hincapie M, Guttman A, Csánky E, Dezso B, Karger BL, Takács L.

Mol Cell Proteomics. 2011 Dec;10(12):M111.010298. doi: 10.1074/mcp.M111.010298. Epub 2011 Sep 26.

44.

Mass spectrometry-based proteomics of human cannabinoid receptor 2: covalent cysteine 6.47(257)-ligand interaction affording megagonist receptor activation.

Szymanski DW, Papanastasiou M, Melchior K, Zvonok N, Mercier RW, Janero DR, Thakur GA, Cha S, Wu B, Karger B, Makriyannis A.

J Proteome Res. 2011 Oct 7;10(10):4789-98. doi: 10.1021/pr2005583. Epub 2011 Sep 13.

45.

Histone deacetylase activity is necessary for left-right patterning during vertebrate development.

Carneiro K, Donnet C, Rejtar T, Karger BL, Barisone GA, Díaz E, Kortagere S, Lemire JM, Levin M.

BMC Dev Biol. 2011 May 20;11:29. doi: 10.1186/1471-213X-11-29.

46.

Rapid high-resolution characterization of functionally important monoclonal antibody N-glycans by capillary electrophoresis.

Szabo Z, Guttman A, Bones J, Karger BL.

Anal Chem. 2011 Jul 1;83(13):5329-36. doi: 10.1021/ac2007587. Epub 2011 Jun 2.

47.

2D-LC analysis of BRP 3 erythropoietin N-glycosylation using anion exchange fractionation and hydrophilic interaction UPLC reveals long poly-N-acetyl lactosamine extensions.

Bones J, McLoughlin N, Hilliard M, Wynne K, Karger BL, Rudd PM.

Anal Chem. 2011 Jun 1;83(11):4154-62. doi: 10.1021/ac200406z. Epub 2011 May 2.

48.

Characterization and comparison of disulfide linkages and scrambling patterns in therapeutic monoclonal antibodies: using LC-MS with electron transfer dissociation.

Wang Y, Lu Q, Wu SL, Karger BL, Hancock WS.

Anal Chem. 2011 Apr 15;83(8):3133-40. doi: 10.1021/ac200128d. Epub 2011 Mar 23.

50.

Retrograde venous cerebral air embolism from disconnected central venous catheter: an experimental model.

Fracasso T, Karger B, Schmidt PF, Reinbold WD, Pfeiffer H.

J Forensic Sci. 2011 Jan;56 Suppl 1:S101-4. doi: 10.1111/j.1556-4029.2010.01572.x. Epub 2010 Sep 30.

PMID:
20887355

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