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Items: 22


Oral-Gut Microbiota and Arthritis: Is There an Evidence-Based Axis?

Lorenzo D, GianVincenzo Z, Carlo Luca R, Karan G, Jorge V, Roberto M, Javad P.

J Clin Med. 2019 Oct 22;8(10). pii: E1753. doi: 10.3390/jcm8101753. Review.


A Novel Glycogen Synthase Kinase-3 Inhibitor Optimized for Acute Myeloid Leukemia Differentiation Activity.

Hu S, Ueda M, Stetson L, Ignatz-Hoover J, Moreton S, Chakrabarti A, Xia Z, Karan G, de Lima M, Agrawal MK, Wald DN.

Mol Cancer Ther. 2016 Jul;15(7):1485-1494. doi: 10.1158/1535-7163.MCT-15-0566. Epub 2016 May 9.


Identification of a Small Molecule That Overcomes HdmX-Mediated Suppression of p53.

Karan G, Wang H, Chakrabarti A, Karan S, Liu Z, Xia Z, Gundluru M, Moreton S, Saunthararajah Y, Jackson MW, Agarwal MK, Wald DN.

Mol Cancer Ther. 2016 Apr;15(4):574-582. doi: 10.1158/1535-7163.MCT-15-0467. Epub 2016 Feb 16.


Disruption of nuclear factor (erythroid-derived-2)-like 2 antioxidant signaling: a mechanism for impaired activation of stem cells and delayed regeneration of skeletal muscle.

Shelar SB, Narasimhan M, Shanmugam G, Litovsky SH, Gounder SS, Karan G, Arulvasu C, Kensler TW, Hoidal JR, Darley-Usmar VM, Rajasekaran NS.

FASEB J. 2016 May;30(5):1865-79. doi: 10.1096/fj.201500153. Epub 2016 Feb 2.


Response: Contributions of the Myf5-independent lineage to myogenesis.

Haldar M, Karan G, Watanabe S, Guenther S, Braun T, Capecchi MR.

Dev Cell. 2014 Dec 8;31(5):539-41. doi: 10.1016/j.devcel.2014.11.010.


Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice.

Yang Z, Chen Y, Lillo C, Chien J, Yu Z, Michaelides M, Klein M, Howes KA, Li Y, Kaminoh Y, Chen H, Zhao C, Chen Y, Al-Sheikh YT, Karan G, Corbeil D, Escher P, Kamaya S, Li C, Johnson S, Frederick JM, Zhao Y, Wang C, Cameron DJ, Huttner WB, Schorderet DF, Munier FL, Moore AT, Birch DG, Baehr W, Hunt DM, Williams DS, Zhang K.

J Clin Invest. 2008 Aug;118(8):2908-16. doi: 10.1172/JCI35891.


A small region in the angiotensin-converting enzyme distal ectodomain is required for cleavage-secretion of the protein at the plasma membrane.

Chattopadhyay S, Karan G, Sen I, Sen GC.

Biochemistry. 2008 Aug 12;47(32):8335-41. doi: 10.1021/bi800702a. Epub 2008 Jul 18.


Two cell lineages, myf5 and myf5-independent, participate in mouse skeletal myogenesis.

Haldar M, Karan G, Tvrdik P, Capecchi MR.

Dev Cell. 2008 Mar;14(3):437-45. doi: 10.1016/j.devcel.2008.01.002.


Elovl4 haploinsufficiency does not induce early onset retinal degeneration in mice.

Li W, Chen Y, Cameron DJ, Wang C, Karan G, Yang Z, Zhao Y, Pearson E, Chen H, Deng C, Howes K, Zhang K.

Vision Res. 2007 Mar;47(5):714-22. Epub 2007 Jan 24.


Treatment with carbonic anhydrase inhibitors depresses electroretinogram responsiveness in mice.

Sauvé Y, Karan G, Yang Z, Li C, Hu J, Zhang K.

Adv Exp Med Biol. 2006;572:439-46. No abstract available.


Fundus appearance of choroideremia using optical coherence tomograpy.

Katz BJ, Yang Z, Payne M, Lin Y, Zhao Y, Pearson E, Duan S, Kamaya S, Karan G, Zhang K.

Adv Exp Med Biol. 2006;572:57-61. No abstract available.


Choroidal neovascularization in patients with adult-onset foveomacular dystrophy caused by mutations in the RDS/peripherin gene.

Moshfeghi DM, Yang Z, Faulkner ND, Karan G, Thirumalaichary S, Pearson E, Zhao Y, Tsai T, Zhang K.

Adv Exp Med Biol. 2006;572:35-40. No abstract available.


Loss of ER retention and sequestration of the wild-type ELOVL4 by Stargardt disease dominant negative mutants.

Karan G, Yang Z, Howes K, Zhao Y, Chen Y, Cameron DJ, Lin Y, Pearson E, Zhang K.

Mol Vis. 2005 Aug 30;11:657-64.


Lipofuscin accumulation, abnormal electrophysiology, and photoreceptor degeneration in mutant ELOVL4 transgenic mice: a model for macular degeneration.

Karan G, Lillo C, Yang Z, Cameron DJ, Locke KG, Zhao Y, Thirumalaichary S, Li C, Birch DG, Vollmer-Snarr HR, Williams DS, Zhang K.

Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4164-9. Epub 2005 Mar 4.


Purification of streptomycin adenylyltransferase from a recombinant Escherichia coli.

Jana S, Karan G, Deb JK.

Protein Expr Purif. 2005 Mar;40(1):86-90.


Mutant carbonic anhydrase 4 impairs pH regulation and causes retinal photoreceptor degeneration.

Yang Z, Alvarez BV, Chakarova C, Jiang L, Karan G, Frederick JM, Zhao Y, Sauvé Y, Li X, Zrenner E, Wissinger B, Hollander AI, Katz B, Baehr W, Cremers FP, Casey JR, Bhattacharya SS, Zhang K.

Hum Mol Genet. 2005 Jan 15;14(2):255-65. Epub 2004 Nov 24.


A novel mutation in the ELOVL4 gene causes autosomal dominant Stargardt-like macular dystrophy.

Maugeri A, Meire F, Hoyng CB, Vink C, Van Regemorter N, Karan G, Yang Z, Cremers FP, Zhang K.

Invest Ophthalmol Vis Sci. 2004 Dec;45(12):4263-7.


A novel RDS/peripherin gene mutation associated with diverse macular phenotypes.

Yang Z, Li Y, Jiang L, Karan G, Moshfeghi D, O'Connor S, Li X, Yu Z, Lewis H, Zack D, Jacobson S, Zhang K.

Ophthalmic Genet. 2004 Jun;25(2):133-45.


Recurrent 17 bp duplication in PITX3 is primarily associated with posterior polar cataract (CPP4).

Berry V, Yang Z, Addison PK, Francis PJ, Ionides A, Karan G, Jiang L, Lin W, Hu J, Yang R, Moore A, Zhang K, Bhattacharya SS.

J Med Genet. 2004 Aug;41(8):e109. No abstract available.


Elovl4 mRNA distribution in the developing mouse retina and phylogenetic conservation of Elovl4 genes.

Zhang XM, Yang Z, Karan G, Hashimoto T, Baehr W, Yang XJ, Zhang K.

Mol Vis. 2003 Jul 3;9:301-7.


Amoebic liver abscess. Review of 220 cases.

Hai AA, Singh A, Mittal VK, Karan GC.

Int Surg. 1991 Apr-Jun;76(2):81-3.


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