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Items: 15


DKK3 (Dikkopf-3) Transdifferentiates Fibroblasts Into Functional Endothelial Cells-Brief Report.

Chen T, Karamariti E, Hong X, Deng J, Wu Y, Gu W, Simpson R, Wong MM, Yu B, Hu Y, Qu A, Xu Q, Zhang L.

Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):765-773. doi: 10.1161/ATVBAHA.118.311919.


DKK3 (Dickkopf 3) Alters Atherosclerotic Plaque Phenotype Involving Vascular Progenitor and Fibroblast Differentiation Into Smooth Muscle Cells.

Karamariti E, Zhai C, Yu B, Qiao L, Wang Z, Potter CMF, Wong MM, Simpson RML, Zhang Z, Wang X, Del Barco Barrantes I, Niehrs C, Kong D, Zhao Q, Zhang Y, Hu Y, Zhang C, Xu Q.

Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):425-437. doi: 10.1161/ATVBAHA.117.310079. Epub 2017 Dec 28.


Adventitial SCA-1+ Progenitor Cell Gene Sequencing Reveals the Mechanisms of Cell Migration in Response to Hyperlipidemia.

Kokkinopoulos I, Wong MM, Potter CMF, Xie Y, Yu B, Warren DT, Nowak WN, Le Bras A, Ni Z, Zhou C, Ruan X, Karamariti E, Hu Y, Zhang L, Xu Q.

Stem Cell Reports. 2017 Aug 8;9(2):681-696. doi: 10.1016/j.stemcr.2017.06.011. Epub 2017 Jul 27.


A Cytokine-Like Protein Dickkopf-Related Protein 3 Is Atheroprotective.

Yu B, Kiechl S, Qi D, Wang X, Song Y, Weger S, Mayr A, Le Bras A, Karamariti E, Zhang Z, Barco Barrantes ID, Niehrs C, Schett G, Hu Y, Wang W, Willeit J, Qu A, Xu Q.

Circulation. 2017 Sep 12;136(11):1022-1036. doi: 10.1161/CIRCULATIONAHA.117.027690. Epub 2017 Jul 3.


Vascular Stem/Progenitor Cell Migration Induced by Smooth Muscle Cell-Derived Chemokine (C-C Motif) Ligand 2 and Chemokine (C-X-C motif) Ligand 1 Contributes to Neointima Formation.

Yu B, Wong MM, Potter CM, Simpson RM, Karamariti E, Zhang Z, Zeng L, Warren D, Hu Y, Wang W, Xu Q.

Stem Cells. 2016 Sep;34(9):2368-80. doi: 10.1002/stem.2410. Epub 2016 Jun 28.


Hyaluronan Is Crucial for Stem Cell Differentiation into Smooth Muscle Lineage.

Simpson RM, Hong X, Wong MM, Karamariti E, Bhaloo SI, Warren D, Kong W, Hu Y, Xu Q.

Stem Cells. 2016 May;34(5):1225-38. doi: 10.1002/stem.2328. Epub 2016 Mar 4.


Dickkopf Homolog 3 Induces Stem Cell Differentiation into Smooth Muscle Lineage via ATF6 Signalling.

Wang X, Karamariti E, Simpson R, Wang W, Xu Q.

J Biol Chem. 2015 Aug 7;290(32):19844-52. doi: 10.1074/jbc.M115.641415. Epub 2015 Jun 23.


Origin and differentiation of vascular smooth muscle cells.

Wang G, Jacquet L, Karamariti E, Xu Q.

J Physiol. 2015 Jul 15;593(14):3013-30. doi: 10.1113/JP270033. Epub 2015 Jun 9. Review.


Generation and grafting of tissue-engineered vessels in a mouse model.

Wong MM, Hong X, Karamariti E, Hu Y, Xu Q.

J Vis Exp. 2015 Mar 18;(97). doi: 10.3791/52565.


Endothelial lineage differentiation from induced pluripotent stem cells is regulated by microRNA-21 and transforming growth factor β2 (TGF-β2) pathways.

Di Bernardini E, Campagnolo P, Margariti A, Zampetaki A, Karamariti E, Hu Y, Xu Q.

J Biol Chem. 2014 Feb 7;289(6):3383-93. doi: 10.1074/jbc.M113.495531. Epub 2013 Dec 19.


Sirolimus stimulates vascular stem/progenitor cell migration and differentiation into smooth muscle cells via epidermal growth factor receptor/extracellular signal-regulated kinase/β-catenin signaling pathway.

Wong MM, Winkler B, Karamariti E, Wang X, Yu B, Simpson R, Chen T, Margariti A, Xu Q.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2397-406. doi: 10.1161/ATVBAHA.113.301595. Epub 2013 Aug 8.


Smooth muscle cells differentiated from reprogrammed embryonic lung fibroblasts through DKK3 signaling are potent for tissue engineering of vascular grafts.

Karamariti E, Margariti A, Winkler B, Wang X, Hong X, Baban D, Ragoussis J, Huang Y, Han JD, Wong MM, Sag CM, Shah AM, Hu Y, Xu Q.

Circ Res. 2013 May 24;112(11):1433-43. doi: 10.1161/CIRCRESAHA.111.300415. Epub 2013 Mar 25.


XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation.

Margariti A, Li H, Chen T, Martin D, Vizcay-Barrena G, Alam S, Karamariti E, Xiao Q, Zampetaki A, Zhang Z, Wang W, Jiang Z, Gao C, Ma B, Chen YG, Cockerill G, Hu Y, Xu Q, Zeng L.

J Biol Chem. 2013 Jan 11;288(2):859-72. doi: 10.1074/jbc.M112.412783. Epub 2012 Nov 26.


Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels.

Margariti A, Winkler B, Karamariti E, Zampetaki A, Tsai TN, Baban D, Ragoussis J, Huang Y, Han JD, Zeng L, Hu Y, Xu Q.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13793-8. doi: 10.1073/pnas.1205526109. Epub 2012 Aug 6.


Histone deacetylase 7 controls endothelial cell growth through modulation of beta-catenin.

Margariti A, Zampetaki A, Xiao Q, Zhou B, Karamariti E, Martin D, Yin X, Mayr M, Li H, Zhang Z, De Falco E, Hu Y, Cockerill G, Xu Q, Zeng L.

Circ Res. 2010 Apr 16;106(7):1202-11. doi: 10.1161/CIRCRESAHA.109.213165. Epub 2010 Mar 11.


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