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Items: 1 to 50 of 71

1.

Reproducing human and cross-species drug toxicities using a Liver-Chip.

Jang KJ, Otieno MA, Ronxhi J, Lim HK, Ewart L, Kodella KR, Petropolis DB, Kulkarni G, Rubins JE, Conegliano D, Nawroth J, Simic D, Lam W, Singer M, Barale E, Singh B, Sonee M, Streeter AJ, Manthey C, Jones B, Srivastava A, Andersson LC, Williams D, Park H, Barrile R, Sliz J, Herland A, Haney S, Karalis K, Ingber DE, Hamilton GA.

Sci Transl Med. 2019 Nov 6;11(517). pii: eaax5516. doi: 10.1126/scitranslmed.aax5516.

PMID:
31694927
2.

Supercritical water anomalies in the vicinity of the Widom line.

Karalis K, Ludwig C, Niceno B.

Sci Rep. 2019 Oct 31;9(1):15731. doi: 10.1038/s41598-019-51843-0.

3.

CRH Promotes the Neurogenic Activity of Neural Stem Cells in the Adult Hippocampus.

Koutmani Y, Gampierakis IA, Polissidis A, Ximerakis M, Koutsoudaki PN, Polyzos A, Agrogiannis G, Karaliota S, Thomaidou D, Rubin LL, Politis PK, Karalis KP.

Cell Rep. 2019 Oct 22;29(4):932-945.e7. doi: 10.1016/j.celrep.2019.09.037.

4.

Bioengineered Human Organ-on-Chip Reveals Intestinal Microenvironment and Mechanical Forces Impacting Shigella Infection.

Grassart A, Malardé V, Gobaa S, Sartori-Rupp A, Kerns J, Karalis K, Marteyn B, Sansonetti P, Sauvonnet N.

Cell Host Microbe. 2019 Oct 9;26(4):565. doi: 10.1016/j.chom.2019.09.007. No abstract available.

PMID:
31600505
5.

Visualization of supercritical water pseudo-boiling at Widom line crossover.

Maxim F, Contescu C, Boillat P, Niceno B, Karalis K, Testino A, Ludwig C.

Nat Commun. 2019 Sep 17;10(1):4114. doi: 10.1038/s41467-019-12117-5.

6.

Bioengineered Human Organ-on-Chip Reveals Intestinal Microenvironment and Mechanical Forces Impacting Shigella Infection.

Grassart A, Malardé V, Gobaa S, Sartori-Rupp A, Kerns J, Karalis K, Marteyn B, Sansonetti P, Sauvonnet N.

Cell Host Microbe. 2019 Sep 11;26(3):435-444.e4. doi: 10.1016/j.chom.2019.08.007. Epub 2019 Sep 3. Erratum in: Cell Host Microbe. 2019 Oct 9;26(4):565.

PMID:
31492657
7.

Evaluation of a new image reconstruction method for digital breast tomosynthesis: effects on the visibility of breast lesions and breast density.

Krammer J, Zolotarev S, Hillman I, Karalis K, Stsepankou D, Vengrinovich V, Hesser J, M Svahn T.

Br J Radiol. 2019 Nov;92(1103):20190345. doi: 10.1259/bjr.20190345. Epub 2019 Sep 5.

PMID:
31453718
8.

Direct determination of amorphous number density from the reduced pair distribution function.

Antipas GSE, Karalis KT.

MethodsX. 2019 Mar 21;6:601-605. doi: 10.1016/j.mex.2019.03.005. eCollection 2019.

9.

Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast.

Liu Z, Pouli D, Alonzo CA, Varone A, Karaliota S, Quinn KP, Münger K, Karalis KP, Georgakoudi I.

Sci Adv. 2018 Mar 7;4(3):eaap9302. doi: 10.1126/sciadv.aap9302. eCollection 2018 Mar.

10.

CD8+ T cells in beige adipogenesis and energy homeostasis.

Moysidou M, Karaliota S, Kodela E, Salagianni M, Koutmani Y, Katsouda A, Kodella K, Tsakanikas P, Ourailidou S, Andreakos E, Kostomitsopoulos N, Skokos D, Chatzigeorgiou A, Chung KJ, Bornstein S, Sleeman MW, Chavakis T, Karalis KP.

JCI Insight. 2018 Mar 8;3(5). pii: 95456. doi: 10.1172/jci.insight.95456.

11.

Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems.

Barrile R, van der Meer AD, Park H, Fraser JP, Simic D, Teng F, Conegliano D, Nguyen J, Jain A, Zhou M, Karalis K, Ingber DE, Hamilton GA, Otieno MA.

Clin Pharmacol Ther. 2018 Dec;104(6):1240-1248. doi: 10.1002/cpt.1054. Epub 2018 Apr 30.

PMID:
29484632
12.

Strain-specific Differences in the Effects of Lymphocytes on the Development of Insulin Resistance and Obesity in Mice.

Kodela E, Moysidou M, Karaliota S, Koutmani Y, Tsakanikas P, Kodella K, Karavia EA, Kypreos KE, Kostomitsopoulos N, Karalis KP.

Comp Med. 2018 Feb 1;68(1):15-24.

13.

Delta-like Ligand-4-Notch Signaling Inhibition Regulates Pancreatic Islet Function and Insulin Secretion.

Billiard F, Karaliota S, Wang B, Stellas D, Serafimidis I, Manousopoulou A, Koutmani Y, Ninou E, Golubov J, DaNave A, Tsakanikas P, Xin Y, Zhang W, Sleeman M, Yancopoulos GD, Murphy AJ, Garbis SD, Karalis K, Skokos D.

Cell Rep. 2018 Jan 23;22(4):895-904. doi: 10.1016/j.celrep.2017.12.076. Epub 2018 Jan 28.

14.

Pragmatic analysis of the electric submerged arc furnace continuum.

Karalis K, Karkalos N, Antipas GSE, Xenidis A.

R Soc Open Sci. 2017 Sep 6;4(9):170313. doi: 10.1098/rsos.170313. eCollection 2017 Sep.

15.

A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity.

Chung KJ, Chatzigeorgiou A, Economopoulou M, Garcia-Martin R, Alexaki VI, Mitroulis I, Nati M, Gebler J, Ziemssen T, Goelz SE, Phieler J, Lim JH, Karalis KP, Papayannopoulou T, Blüher M, Hajishengallis G, Chavakis T.

Nat Immunol. 2017 Jun;18(6):654-664. doi: 10.1038/ni.3728. Epub 2017 Apr 17.

16.

Erratum: Bona-fide method for the determination of short range order and transport properties in a ferro-aluminosilicate slag.

Karalis KT, Dellis D, Antipas GS, Xenidis A.

Sci Rep. 2016 Sep 27;6:33765. doi: 10.1038/srep33765. No abstract available.

17.

Metformin protects against infection-induced myocardial dysfunction.

Tzanavari T, Varela A, Theocharis S, Ninou E, Kapelouzou A, Cokkinos DV, Kontaridis MI, Karalis KP.

Metabolism. 2016 Oct;65(10):1447-58. doi: 10.1016/j.metabol.2016.06.012. Epub 2016 Jul 9.

18.

Two-photon excited fluorescence of intrinsic fluorophores enables label-free assessment of adipose tissue function.

Alonzo CA, Karaliota S, Pouli D, Liu Z, Karalis KP, Georgakoudi I.

Sci Rep. 2016 Aug 5;6:31012. doi: 10.1038/srep31012.

19.

Bona-fide method for the determination of short range order and transport properties in a ferro-aluminosilicate slag.

Karalis KT, Dellis D, Antipas GS, Xenidis A.

Sci Rep. 2016 Jul 26;6:30216. doi: 10.1038/srep30216.

20.

Hypothalamus proteomics from mouse models with obesity and anorexia reveals therapeutic targets of appetite regulation.

Manousopoulou A, Koutmani Y, Karaliota S, Woelk CH, Manolakos ES, Karalis K, Garbis SD.

Nutr Diabetes. 2016 Apr 25;6:e204. doi: 10.1038/nutd.2016.10.

21.

Identification of a novel interaction between corticotropin releasing hormone (Crh) and macroautophagy.

Giannogonas P, Apostolou A, Manousopoulou A, Theocharis S, Macari SA, Psarras S, Garbis SD, Pothoulakis C, Karalis KP.

Sci Rep. 2016 Mar 18;6:23342. doi: 10.1038/srep23342.

22.

Neural stem cells respond to stress hormones: distinguishing beneficial from detrimental stress.

Koutmani Y, Karalis KP.

Front Physiol. 2015 Mar 11;6:77. doi: 10.3389/fphys.2015.00077. eCollection 2015. Review.

23.

Engineered in vitro disease models.

Benam KH, Dauth S, Hassell B, Herland A, Jain A, Jang KJ, Karalis K, Kim HJ, MacQueen L, Mahmoodian R, Musah S, Torisawa YS, van der Meer AD, Villenave R, Yadid M, Parker KK, Ingber DE.

Annu Rev Pathol. 2015;10:195-262. doi: 10.1146/annurev-pathol-012414-040418. Review.

PMID:
25621660
24.

Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation.

Chatzigeorgiou A, Chung KJ, Garcia-Martin R, Alexaki VI, Klotzsche-von Ameln A, Phieler J, Sprott D, Kanczkowski W, Tzanavari T, Bdeir M, Bergmann S, Cartellieri M, Bachmann M, Nikolakopoulou P, Androutsellis-Theotokis A, Siegert G, Bornstein SR, Muders MH, Boon L, Karalis KP, Lutgens E, Chavakis T.

Hepatology. 2014 Oct;60(4):1196-210. doi: 10.1002/hep.27233. Epub 2014 Aug 21.

PMID:
24845056
25.

Atomic order and cluster energetics of a 17 wt% Si-based glass versus the liquid phase.

Antipas GS, Temleitner L, Karalis K, Pusztai L, Xenidis A.

J Phys Condens Matter. 2013 Nov 13;25(45):454206. doi: 10.1088/0953-8984/25/45/454206. Epub 2013 Oct 18.

PMID:
24141046
26.

The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance.

Phieler J, Chung KJ, Chatzigeorgiou A, Klotzsche-von Ameln A, Garcia-Martin R, Sprott D, Moisidou M, Tzanavari T, Ludwig B, Baraban E, Ehrhart-Bornstein M, Bornstein SR, Mziaut H, Solimena M, Karalis KP, Economopoulou M, Lambris JD, Chavakis T.

J Immunol. 2013 Oct 15;191(8):4367-74. doi: 10.4049/jimmunol.1300038. Epub 2013 Sep 16.

27.

Corticotropin-releasing hormone exerts direct effects on neuronal progenitor cells: implications for neuroprotection.

Koutmani Y, Politis PK, Elkouris M, Agrogiannis G, Kemerli M, Patsouris E, Remboutsika E, Karalis KP.

Mol Psychiatry. 2013 Mar;18(3):300-7. doi: 10.1038/mp.2012.198. Epub 2013 Feb 5.

28.

cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation.

Bucci M, Papapetropoulos A, Vellecco V, Zhou Z, Zaid A, Giannogonas P, Cantalupo A, Dhayade S, Karalis KP, Wang R, Feil R, Cirino G.

PLoS One. 2012;7(12):e53319. doi: 10.1371/journal.pone.0053319. Epub 2012 Dec 28.

29.

Lymphocytes in obesity-related adipose tissue inflammation.

Chatzigeorgiou A, Karalis KP, Bornstein SR, Chavakis T.

Diabetologia. 2012 Oct;55(10):2583-2592. doi: 10.1007/s00125-012-2607-0. Epub 2012 Jun 26. Review.

PMID:
22733483
30.

Modulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11beta-hydroxysteroid dehydrogenase.

Schmid J, Ludwig B, Schally AV, Steffen A, Ziegler CG, Block NL, Koutmani Y, Brendel MD, Karalis KP, Simeonovic CJ, Licinio J, Ehrhart-Bornstein M, Bornstein SR.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13722-7. doi: 10.1073/pnas.1110965108. Epub 2011 Aug 8.

31.

A novel role of peripheral corticotropin-releasing hormone (CRH) on dermal fibroblasts.

Rassouli O, Liapakis G, Lazaridis I, Sakellaris G, Gkountelias K, Gravanis A, Margioris AN, Karalis KP, Venihaki M.

PLoS One. 2011;6(7):e21654. doi: 10.1371/journal.pone.0021654. Epub 2011 Jul 13.

32.

Corticotropin-releasing factor regulates TLR4 expression in the colon and protects mice from colitis.

Chaniotou Z, Giannogonas P, Theoharis S, Teli T, Gay J, Savidge T, Koutmani Y, Brugni J, Kokkotou E, Pothoulakis C, Karalis KP.

Gastroenterology. 2010 Dec;139(6):2083-92. doi: 10.1053/j.gastro.2010.08.024. Epub 2010 Aug 20.

PMID:
20732324
33.

TNF-alpha and obesity.

Tzanavari T, Giannogonas P, Karalis KP.

Curr Dir Autoimmun. 2010;11:145-56. doi: 10.1159/000289203. Epub 2010 Feb 18. Review.

PMID:
20173393
34.

Mechanisms of obesity and related pathology: linking immune responses to metabolic stress.

Karalis KP, Giannogonas P, Kodela E, Koutmani Y, Zoumakis M, Teli T.

FEBS J. 2009 Oct;276(20):5747-54. doi: 10.1111/j.1742-4658.2009.07304.x. Epub 2009 Sep 15. Review.

35.

Activation of phosphatidylinositol 3-kinase/protein kinase B by corticotropin-releasing factor in human monocytes.

Chandras C, Koutmani Y, Kokkotou E, Pothoulakis C, Karalis KP.

Endocrinology. 2009 Oct;150(10):4606-14. doi: 10.1210/en.2008-1810. Epub 2009 Jul 23.

36.

Corticotropin-releasing hormone deficiency is associated with reduced local inflammation in a mouse model of experimental colitis.

Gay J, Kokkotou E, O'Brien M, Pothoulakis C, Karalis KP.

Endocrinology. 2008 Jul;149(7):3403-9. doi: 10.1210/en.2007-1703. Epub 2008 Apr 10.

37.

Urocortin II mediates pro-inflammatory effects in human colonocytes via corticotropin-releasing hormone receptor 2alpha.

Moss AC, Anton P, Savidge T, Newman P, Cheifetz AS, Gay J, Paraschos S, Winter MW, Moyer MP, Karalis K, Kokkotou E, Pothoulakis C.

Gut. 2007 Sep;56(9):1210-7. Epub 2007 Apr 5.

38.

Antiproliferative effect of adiponectin on MCF7 breast cancer cells: a potential hormonal link between obesity and cancer.

Arditi JD, Venihaki M, Karalis KP, Chrousos GP.

Horm Metab Res. 2007 Jan;39(1):9-13.

PMID:
17226107
39.

Regulation of appetite and insulin signaling in inflammatory states.

Teli T, Xanthaki D, Karalis KP.

Ann N Y Acad Sci. 2006 Nov;1083:319-28. Review.

PMID:
17148747
40.

Terbutaline inhibits corticotropin-releasing hormone (CRH) expression in human trophoblast cells.

Kontopoulos EV, Chandras C, Karalis K.

J Matern Fetal Neonatal Med. 2006 Nov;19(11):735-9.

PMID:
17127497
41.

Interleukin-6 genetic ablation protects from trinitrobenzene sulfonic acid-induced colitis in mice. Putative effect of antiinflammatory cytokines.

Gay J, Kokkotou E, O'Brien M, Pothoulakis C, Karalis KP.

Neuroimmunomodulation. 2006;13(2):114-21. Epub 2006 Oct 14.

PMID:
17077645
42.

Corticotropin-releasing hormone receptor 2-deficient mice have reduced intestinal inflammatory responses.

Kokkotou E, Torres D, Moss AC, O'Brien M, Grigoriadis DE, Karalis K, Pothoulakis C.

J Immunol. 2006 Sep 1;177(5):3355-61.

43.

Corticotropin-releasing hormone contributes to the peripheral inflammatory response in experimental autoimmune encephalomyelitis.

Benou C, Wang Y, Imitola J, VanVlerken L, Chandras C, Karalis KP, Khoury SJ.

J Immunol. 2005 May 1;174(9):5407-13.

44.

Corticotropin-releasing hormone (CRH) requirement in Clostridium difficile toxin A-mediated intestinal inflammation.

Anton PM, Gay J, Mykoniatis A, Pan A, O'Brien M, Brown D, Karalis K, Pothoulakis C.

Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8503-8. Epub 2004 May 24.

45.

NF-kappaB participates in the corticotropin-releasing, hormone-induced regulation of the pituitary proopiomelanocortin gene.

Karalis KP, Venihaki M, Zhao J, van Vlerken LE, Chandras C.

J Biol Chem. 2004 Mar 19;279(12):10837-40. Epub 2004 Jan 6.

46.

Corticotropin-releasing hormone deficiency results in impaired splenocyte response to lipopolysaccharide.

Venihaki M, Zhao J, Karalis KP.

J Neuroimmunol. 2003 Aug;141(1-2):3-9.

PMID:
12965248
47.

Stress-induced interleukin-6 release in mice is mast cell-dependent and more pronounced in Apolipoprotein E knockout mice.

Huang M, Pang X, Karalis K, Theoharides TC.

Cardiovasc Res. 2003 Jul 1;59(1):241-9.

PMID:
12829195
48.

Leptin mediates Clostridium difficile toxin A-induced enteritis in mice.

Mykoniatis A, Anton PM, Wlk M, Wang CC, Ungsunan L, Blüher S, Venihaki M, Simeonidis S, Zacks J, Zhao D, Sougioultzis S, Karalis K, Mantzoros C, Pothoulakis C.

Gastroenterology. 2003 Mar;124(3):683-91.

PMID:
12612907
49.

Mast cell deficient W/W(v) mice lack stress-induced increase in serum IL-6 levels, as well as in peripheral CRH and vascular permeability, a model of rheumatoid arthritis.

Huang M, Berry J, Kandere K, Lytinas M, Karalis K, Theoharides TC.

Int J Immunopathol Pharmacol. 2002 Sep-Dec;15(3):249-254.

PMID:
12575928
50.

Regulation of nuclear factor-kappaB by corticotropin-releasing hormone in mouse thymocytes.

Zhao J, Karalis KP.

Mol Endocrinol. 2002 Nov;16(11):2561-70.

PMID:
12403845

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