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Items: 11

1.

GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration.

Ackeifi C, Wang P, Karakose E, Manning Fox JE, González BJ, Liu H, Wilson J, Swartz E, Berrouet C, Li Y, Kumar K, MacDonald PE, Sanchez R, Thorens B, DeVita R, Homann D, Egli D, Scott DK, Garcia-Ocaña A, Stewart AF.

Sci Transl Med. 2020 Feb 12;12(530). pii: eaaw9996. doi: 10.1126/scitranslmed.aaw9996.

PMID:
32051230
2.

Relationship between Sarcopenia and Surgical Site Infection in Patients Undergoing Colorectal Cancer Surgical Procedures.

Olmez T, Karakose E, Keklikkiran ZZ, Ofluoglu CB, Bas T, Uzun O, Duman M, Polat E.

Surg Infect (Larchmt). 2019 Dec 20. doi: 10.1089/sur.2019.285. [Epub ahead of print]

PMID:
31859591
3.

Pharmacologic and genetic approaches define human pancreatic β cell mitogenic targets of DYRK1A inhibitors.

Ackeifi C, Swartz E, Kumar K, Liu H, Chalada S, Karakose E, Scott DK, Garcia-Ocaña A, Sanchez R, DeVita RJ, Stewart AF, Wang P.

JCI Insight. 2020 Jan 16;5(1). pii: 132594. doi: 10.1172/jci.insight.132594.

4.

Epigenetic modulation of β cells by interferon-α via PNPT1/mir-26a/TET2 triggers autoimmune diabetes.

Stefan-Lifshitz M, Karakose E, Cui L, Ettela A, Yi Z, Zhang W, Tomer Y.

JCI Insight. 2019 Mar 7;4(5). pii: 126663. doi: 10.1172/jci.insight.126663. eCollection 2019 Mar 7.

5.

Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells.

Wang P, Karakose E, Liu H, Swartz E, Ackeifi C, Zlatanic V, Wilson J, González BJ, Bender A, Takane KK, Ye L, Harb G, Pagliuca F, Homann D, Egli D, Argmann C, Scott DK, Garcia-Ocaña A, Stewart AF.

Cell Metab. 2019 Mar 5;29(3):638-652.e5. doi: 10.1016/j.cmet.2018.12.005. Epub 2018 Dec 20.

PMID:
30581122
6.

Advances in drug discovery for human beta cell regeneration.

Karakose E, Ackeifi C, Wang P, Stewart AF.

Diabetologia. 2018 Aug;61(8):1693-1699. doi: 10.1007/s00125-018-4639-6. Epub 2018 May 16. Review.

7.

Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas.

Wang H, Bender A, Wang P, Karakose E, Inabnet WB, Libutti SK, Arnold A, Lambertini L, Stang M, Chen H, Kasai Y, Mahajan M, Kinoshita Y, Fernandez-Ranvier G, Becker TC, Takane KK, Walker LA, Saul S, Chen R, Scott DK, Ferrer J, Antipin Y, Donovan M, Uzilov AV, Reva B, Schadt EE, Losic B, Argmann C, Stewart AF.

Nat Commun. 2017 Oct 3;8(1):767. doi: 10.1038/s41467-017-00992-9.

8.

The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites.

Karaköse E, Geiger T, Flynn K, Lorenz-Baath K, Zent R, Mann M, Fässler R.

J Cell Sci. 2015 Mar 1;128(5):1023-33. doi: 10.1242/jcs.162545. Epub 2015 Jan 20.

9.

PINCH-1 promotes Bcl-2-dependent survival signalling and inhibits JNK-mediated apoptosis in the primitive endoderm.

Montanez E, Karaköse E, Tischner D, Villunger A, Fässler R.

J Cell Sci. 2012 Nov 1;125(Pt 21):5233-40. doi: 10.1242/jcs.112029. Epub 2012 Sep 3.

10.

The kindlins at a glance.

Karaköse E, Schiller HB, Fässler R.

J Cell Sci. 2010 Jul 15;123(Pt 14):2353-6. doi: 10.1242/jcs.064600. Review. No abstract available.

11.

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