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Items: 33


Assessing Tumor Microenvironment of Metastasis Doorway-Mediated Vascular Permeability Associated with Cancer Cell Dissemination using Intravital Imaging and Fixed Tissue Analysis.

Karagiannis GS, Pastoriza JM, Borriello L, Jafari R, Coste A, Condeelis JS, Oktay MH, Entenberg D.

J Vis Exp. 2019 Jun 26;(148). doi: 10.3791/59633.


The emerging roles of macrophages in cancer metastasis and response to chemotherapy.

Sanchez LR, Borriello L, Entenberg D, Condeelis JS, Oktay MH, Karagiannis GS.

J Leukoc Biol. 2019 Feb 5. doi: 10.1002/JLB.MR0218-056RR. [Epub ahead of print] Review.


Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth.

Mao SPH, Park M, Cabrera RM, Christin JR, Karagiannis GS, Oktay MH, Zaiss DMW, Abrams SI, Guo W, Condeelis JS, Kenny PA, Segall JE.

Breast Cancer Res. 2018 Oct 26;20(1):131. doi: 10.1186/s13058-018-1057-0.


Black race and distant recurrence after neoadjuvant or adjuvant chemotherapy in breast cancer.

Pastoriza JM, Karagiannis GS, Lin J, Lanjewar S, Entenberg D, Condeelis JS, Sparano JA, Xue X, Rohan TE, Oktay MH.

Clin Exp Metastasis. 2018 Oct;35(7):613-623. doi: 10.1007/s10585-018-9932-8. Epub 2018 Aug 22.


Chemotherapy-induced metastasis in breast cancer.

Karagiannis GS, Condeelis JS, Oktay MH.

Oncotarget. 2017 Nov 27;8(67):110733-110734. doi: 10.18632/oncotarget.22717. eCollection 2017 Dec 19. No abstract available.


Chemotherapy-induced metastasis: mechanisms and translational opportunities.

Karagiannis GS, Condeelis JS, Oktay MH.

Clin Exp Metastasis. 2018 Apr;35(4):269-284. doi: 10.1007/s10585-017-9870-x. Epub 2018 Jan 6. Review.


A permanent window for the murine lung enables high-resolution imaging of cancer metastasis.

Entenberg D, Voiculescu S, Guo P, Borriello L, Wang Y, Karagiannis GS, Jones J, Baccay F, Oktay M, Condeelis J.

Nat Methods. 2018 Jan;15(1):73-80. doi: 10.1038/nmeth.4511. Epub 2017 Nov 27.


Inflammation-driven colon neoplasmatogenesis in uPA-deficient mice is associated with an increased expression of Runx transcriptional regulators.

Afaloniati H, Karagiannis GS, Hardas A, Poutahidis T, Angelopoulou K.

Exp Cell Res. 2017 Dec 15;361(2):257-264. doi: 10.1016/j.yexcr.2017.10.025. Epub 2017 Oct 26.


The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors.

Harney AS, Karagiannis GS, Pignatelli J, Smith BD, Kadioglu E, Wise SC, Hood MM, Kaufman MD, Leary CB, Lu WP, Al-Ani G, Chen X, Entenberg D, Oktay MH, Wang Y, Chun L, De Palma M, Jones JG, Flynn DL, Condeelis JS.

Mol Cancer Ther. 2017 Nov;16(11):2486-2501. doi: 10.1158/1535-7163.MCT-17-0241. Epub 2017 Aug 24.


HtrA3 stromal expression is correlated with tumor budding in stage II colorectal cancer.

Forse CL, Rahimi M, Diamandis EP, Assarzadegan N, Dawson H, Grin A, Kennedy E, O'Connor B, Messenger DE, Riddell RH, Kirsch R, Karagiannis GS.

Exp Mol Pathol. 2017 Aug;103(1):94-100. doi: 10.1016/j.yexmp.2017.07.002. Epub 2017 Jul 15.


Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism.

Karagiannis GS, Pastoriza JM, Wang Y, Harney AS, Entenberg D, Pignatelli J, Sharma VP, Xue EA, Cheng E, D'Alfonso TM, Jones JG, Anampa J, Rohan TE, Sparano JA, Condeelis JS, Oktay MH.

Sci Transl Med. 2017 Jul 5;9(397). pii: eaan0026. doi: 10.1126/scitranslmed.aan0026. Erratum in: Sci Transl Med. 2017 Jul 19;9(399):.


Signatures of breast cancer metastasis at a glance.

Karagiannis GS, Goswami S, Jones JG, Oktay MH, Condeelis JS.

J Cell Sci. 2016 May 1;129(9):1751-8. doi: 10.1242/jcs.183129. Epub 2016 Apr 15. Review.


Kallikrein-related peptidases (KLKs) and the hallmarks of cancer.

Filippou PS, Karagiannis GS, Musrap N, Diamandis EP.

Crit Rev Clin Lab Sci. 2016 Aug;53(4):277-91. doi: 10.3109/10408363.2016.1154643. Epub 2016 May 5. Review.


BMP pathway suppression is an early event in inflammation-driven colon neoplasmatogenesis of uPA-deficient mice.

Karagiannis GS, Afaloniati H, Karamanavi E, Poutahidis T, Angelopoulou K.

Tumour Biol. 2016 Feb;37(2):2243-55. doi: 10.1007/s13277-015-3988-8. Epub 2015 Sep 10.


Comparative Proteomics of Ovarian Cancer Aggregate Formation Reveals an Increased Expression of Calcium-activated Chloride Channel Regulator 1 (CLCA1).

Musrap N, Tuccitto A, Karagiannis GS, Saraon P, Batruch I, Diamandis EP.

J Biol Chem. 2015 Jul 10;290(28):17218-27. doi: 10.1074/jbc.M115.639773. Epub 2015 May 24.


Bone morphogenetic protein antagonist gremlin-1 regulates colon cancer progression.

Karagiannis GS, Musrap N, Saraon P, Treacy A, Schaeffer DF, Kirsch R, Riddell RH, Diamandis EP.

Biol Chem. 2015 Feb;396(2):163-83. doi: 10.1515/hsz-2014-0221.


Expression patterns of bone morphogenetic protein antagonists in colorectal cancer desmoplastic invasion fronts.

Karagiannis GS, Treacy A, Messenger D, Grin A, Kirsch R, Riddell RH, Diamandis EP.

Mol Oncol. 2014 Oct;8(7):1240-52. doi: 10.1016/j.molonc.2014.04.004. Epub 2014 Apr 19.


Proteomic analysis of cancer and mesothelial cells reveals an increase in Mucin 5AC during ovarian cancer and peritoneal interaction.

Musrap N, Karagiannis GS, Saraon P, Batruch I, Smith C, Diamandis EP.

J Proteomics. 2014 May 30;103:204-15. doi: 10.1016/j.jprot.2014.03.042. Epub 2014 Apr 12.


In-depth proteomic delineation of the colorectal cancer exoproteome: Mechanistic insight and identification of potential biomarkers.

Karagiannis GS, Pavlou MP, Saraon P, Musrap N, Xie A, Batruch I, Prassas I, Dimitromanolakis A, Petraki C, Diamandis EP.

J Proteomics. 2014 May 30;103:121-36. doi: 10.1016/j.jprot.2014.03.018. Epub 2014 Mar 27.


Collective migration of cancer-associated fibroblasts is enhanced by overexpression of tight junction-associated proteins claudin-11 and occludin.

Karagiannis GS, Schaeffer DF, Cho CK, Musrap N, Saraon P, Batruch I, Grin A, Mitrovic B, Kirsch R, Riddell RH, Diamandis EP.

Mol Oncol. 2014 Mar;8(2):178-95. doi: 10.1016/j.molonc.2013.10.008. Epub 2013 Nov 8.


Proteomic signatures of angiogenesis in androgen-independent prostate cancer.

Karagiannis GS, Saraon P, Jarvi KA, Diamandis EP.

Prostate. 2014 Feb;74(3):260-72. doi: 10.1002/pros.22747. Epub 2013 Oct 26.


Enrichment map profiling of the cancer invasion front suggests regulation of colorectal cancer progression by the bone morphogenetic protein antagonist, gremlin-1.

Karagiannis GS, Berk A, Dimitromanolakis A, Diamandis EP.

Mol Oncol. 2013 Aug;7(4):826-39. doi: 10.1016/j.molonc.2013.04.002. Epub 2013 Apr 18.


Quantitative proteomics reveals that enzymes of the ketogenic pathway are associated with prostate cancer progression.

Saraon P, Cretu D, Musrap N, Karagiannis GS, Batruch I, Drabovich AP, van der Kwast T, Mizokami A, Morrissey C, Jarvi K, Diamandis EP.

Mol Cell Proteomics. 2013 Jun;12(6):1589-601. doi: 10.1074/mcp.M112.023887. Epub 2013 Feb 26.


Quantitative proteomic analysis of amniocytes reveals potentially dysregulated molecular networks in Down syndrome.

Cho CK, Drabovich AP, Karagiannis GS, Martínez-Morillo E, Dason S, Dimitromanolakis A, Diamandis EP.

Clin Proteomics. 2013 Feb 8;10(1):2. doi: 10.1186/1559-0275-10-2.


Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformation.

Karagiannis GS, Weile J, Bader GD, Minta J.

BMC Cardiovasc Disord. 2013 Jan 16;13:4. doi: 10.1186/1471-2261-13-4.


Cancer-associated fibroblasts drive the progression of metastasis through both paracrine and mechanical pressure on cancer tissue.

Karagiannis GS, Poutahidis T, Erdman SE, Kirsch R, Riddell RH, Diamandis EP.

Mol Cancer Res. 2012 Nov;10(11):1403-18. doi: 10.1158/1541-7786.MCR-12-0307. Epub 2012 Sep 28. Review.


Proteomic profiling of androgen-independent prostate cancer cell lines reveals a role for protein S during the development of high grade and castration-resistant prostate cancer.

Saraon P, Musrap N, Cretu D, Karagiannis GS, Batruch I, Smith C, Drabovich AP, Trudel D, van der Kwast T, Morrissey C, Jarvi KA, Diamandis EP.

J Biol Chem. 2012 Oct 5;287(41):34019-31. doi: 10.1074/jbc.M112.384438. Epub 2012 Aug 20.


Proteomic signatures of the desmoplastic invasion front reveal collagen type XII as a marker of myofibroblastic differentiation during colorectal cancer metastasis.

Karagiannis GS, Petraki C, Prassas I, Saraon P, Musrap N, Dimitromanolakis A, Diamandis EP.

Oncotarget. 2012 Mar;3(3):267-85.


Digitoxin-induced cytotoxicity in cancer cells is mediated through distinct kinase and interferon signaling networks.

Prassas I, Karagiannis GS, Batruch I, Dimitromanolakis A, Datti A, Diamandis EP.

Mol Cancer Ther. 2011 Nov;10(11):2083-93. doi: 10.1158/1535-7163.MCT-11-0421. Epub 2011 Aug 22.


Cancer secretomics reveal pathophysiological pathways in cancer molecular oncology.

Karagiannis GS, Pavlou MP, Diamandis EP.

Mol Oncol. 2010 Dec;4(6):496-510. doi: 10.1016/j.molonc.2010.09.001. Epub 2010 Sep 16. Review.


Structural characterization and expression of five novel canine kallikrein-related peptidases in mammary cancer.

Angelopoulou K, Karagiannis GS.

Mamm Genome. 2010 Oct;21(9-10):516-24. doi: 10.1007/s00335-010-9282-6. Epub 2010 Sep 19.


The canine kallikrein-related peptidases 9 and 10: structural characterization and expression in mammary cancer.

Angelopoulou K, Karagiannis GS.

Mamm Genome. 2009 Nov-Dec;20(11-12):758-67. doi: 10.1007/s00335-009-9237-y. Epub 2009 Dec 2.


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