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Items: 17

1.

Chasing tails: Cathepsin-L improves structural analysis of histones by HX-MS.

Papanastasiou M, Mullahoo J, DeRuff KC, Bajrami B, Karageorgos I, Johnston SE, Peckner R, Myers SA, Carr SA, Jaffe JD.

Mol Cell Proteomics. 2019 Aug 13. pii: mcp.RA119.001325. doi: 10.1074/mcp.RA119.001325. [Epub ahead of print]

2.

Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb.

Hudgens JW, Gallagher ES, Karageorgos I, Anderson KW, Filliben JJ, Huang RY, Chen G, Bou-Assaf GM, Espada A, Chalmers MJ, Harguindey E, Zhang HM, Walters BT, Zhang J, Venable J, Steckler C, Park I, Brock A, Lu X, Pandey R, Chandramohan A, Anand GS, Nirudodhi SN, Sperry JB, Rouse JC, Carroll JA, Rand KD, Leurs U, Weis DD, Al-Naqshabandi MA, Hageman TS, Deredge D, Wintrode PL, Papanastasiou M, Lambris JD, Li S, Urata S.

Anal Chem. 2019 Jun 4;91(11):7336-7345. doi: 10.1021/acs.analchem.9b01100. Epub 2019 May 14.

PMID:
31045344
3.

Structure of the Fc fragment of the NIST reference antibody RM8671.

Gallagher DT, Galvin CV, Karageorgos I.

Acta Crystallogr F Struct Biol Commun. 2018 Sep 1;74(Pt 9):524-529. doi: 10.1107/S2053230X18009834. Epub 2018 Aug 29.

4.

Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase.

Tyukhtenko S, Rajarshi G, Karageorgos I, Zvonok N, Gallagher ES, Huang H, Vemuri K, Hudgens JW, Ma X, Nasr ML, Pavlopoulos S, Makriyannis A.

Sci Rep. 2018 Jan 29;8(1):1719. doi: 10.1038/s41598-017-19135-7.

5.

Data on crystal organization in the structure of the Fab fragment from the NIST reference antibody, RM 8671.

Gallagher DT, Karageorgos I, Hudgens JW, Galvin CV.

Data Brief. 2017 Nov 8;16:29-36. doi: 10.1016/j.dib.2017.11.013. eCollection 2018 Feb.

6.

Biophysical characterization and structure of the Fab fragment from the NIST reference antibody, RM 8671.

Karageorgos I, Gallagher ES, Galvin C, Gallagher DT, Hudgens JW.

Biologicals. 2017 Nov;50:27-34. doi: 10.1016/j.biologicals.2017.09.005. Epub 2017 Sep 29.

7.

The role of human monoacylglycerol lipase (hMAGL) binding pocket in breakup of unsaturated phospholipid membranes.

Karageorgos I, Silin VI, Zvonok N, Marino J, Janero DR, Makriyannis A.

Anal Biochem. 2017 Nov 1;536:90-95. doi: 10.1016/j.ab.2017.08.009. Epub 2017 Aug 17.

PMID:
28822686
8.

Structural characterization of membrane-bound human immunodeficiency virus-1 Gag matrix with neutron reflectometry.

Eells R, Barros M, Scott KM, Karageorgos I, Heinrich F, Lösche M.

Biointerphases. 2017 May 16;12(2):02D408. doi: 10.1116/1.4983155.

9.

Soluble analog of ApoER2 targeting beta2-glycoprotein I in immune complexes counteracts hypertension in lupus-prone mice with spontaneous antiphospholipid syndrome.

Kolyada A, Ke Q, Karageorgos I, Mahlawat P, Barrios DA, Kang PM, Beglova N.

J Thromb Haemost. 2016 Jun;14(6):1298-307. doi: 10.1111/jth.13314. Epub 2016 May 3.

10.

Membrane Binding of HIV-1 Matrix Protein: Dependence on Bilayer Composition and Protein Lipidation.

Barros M, Heinrich F, Datta SAK, Rein A, Karageorgos I, Nanda H, Lösche M.

J Virol. 2016 Apr 14;90(9):4544-4555. doi: 10.1128/JVI.02820-15. Print 2016 May.

11.

Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES.

Tyukhtenko S, Karageorgos I, Rajarshi G, Zvonok N, Pavlopoulos S, Janero DR, Makriyannis A.

J Biol Chem. 2016 Feb 5;291(6):2556-65. doi: 10.1074/jbc.M115.670257. Epub 2015 Nov 10.

12.

Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach.

Karageorgos I, Mizzi C, Giannopoulou E, Pavlidis C, Peters BA, Zagoriti Z, Stenson PD, Mitropoulos K, Borg J, Kalofonos HP, Drmanac R, Stubbs A, van der Spek P, Cooper DN, Katsila T, Patrinos GP.

Hum Genomics. 2015 Jun 20;9:12. doi: 10.1186/s40246-015-0034-2.

13.

An A1-A1 mutant with improved binding and inhibition of β2GPI/antibody complexes in antiphospholipid syndrome.

Kolyada A, Karageorgos I, Mahlawat P, Beglova N.

FEBS J. 2015 Mar;282(5):864-73. doi: 10.1111/febs.13185. Epub 2015 Jan 27.

14.

Active-site inhibitors modulate the dynamic properties of human monoacylglycerol lipase: a hydrogen exchange mass spectrometry study.

Karageorgos I, Wales TE, Janero DR, Zvonok N, Vemuri VK, Engen JR, Makriyannis A.

Biochemistry. 2013 Jul 23;52(29):5016-26. doi: 10.1021/bi400430k. Epub 2013 Jul 8.

15.

Endocannabinoid enzyme engineering: soluble human thio-monoacylglycerol lipase (sol-S-hMGL).

Karageorgos I, Zvonok N, Janero DR, Vemuri VK, Shukla V, Wales TE, Engen JR, Makriyannis A.

ACS Chem Neurosci. 2012 May 16;3(5):393-9. doi: 10.1021/cn3000263. Epub 2012 Mar 20.

16.
17.

Covalent inhibitors of human monoacylglycerol lipase: ligand-assisted characterization of the catalytic site by mass spectrometry and mutational analysis.

Zvonok N, Pandarinathan L, Williams J, Johnston M, Karageorgos I, Janero DR, Krishnan SC, Makriyannis A.

Chem Biol. 2008 Aug 25;15(8):854-62. doi: 10.1016/j.chembiol.2008.06.008.

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