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Items: 1 to 50 of 470

1.

Gastrointestinal microbiota contributes to the development of murine transfusion-related acute lung injury.

Kapur R, Kim M, Rebetz J, Hallström B, Björkman JT, Takabe-French A, Kim N, Liu J, Shanmugabhavananthan S, Milosevic S, McVey MJ, Speck ER, Semple JW.

Blood Adv. 2018 Jul 10;2(13):1651-1663. doi: 10.1182/bloodadvances.2018018903.

2.

Antiplatelet antibody-induced thrombocytopenia does not correlate with megakaryocyte abnormalities in murine immune thrombocytopenia.

Guo L, Kapur R, Aslam R, Hunt K, Hou Y, Zufferey A, Speck ER, Rondina MT, Lazarus AH, Ni H, Semple JW.

Scand J Immunol. 2018 Jul;88(1):e12678. doi: 10.1111/sji.12678.

PMID:
29855061
3.

Parallel detection of lactobacillus and bacterial vaginosis-associated bacterial DNA in the chorioamnion and vagina of pregnant women at term.

Lannon SMR, Adams Waldorf KM, Fiedler T, Kapur RP, Agnew K, Rajagopal L, Gravett MG, Fredricks DN.

J Matern Fetal Neonatal Med. 2018 Mar 12:1-9. doi: 10.1080/14767058.2018.1446208. [Epub ahead of print]

PMID:
29478370
4.

Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway.

Palam LR, Mali RS, Ramdas B, Srivatsan SN, Visconte V, Tiu RV, Vanhaesebroeck B, Roers A, Gerbaulet A, Xu M, Janga SC, Takemoto CM, Paczesny S, Kapur R.

JCI Insight. 2018 Feb 22;3(4). pii: 94679. doi: 10.1172/jci.insight.94679. [Epub ahead of print]

5.

Rapid development of myeloproliferative neoplasm in mice with Ptpn11D61Y mutation and haploinsufficient for Dnmt3a.

Deng L, Richine BM, Virts EL, Jideonwo-Auman VN, Chan RJ, Kapur R.

Oncotarget. 2017 Dec 26;9(5):6055-6061. doi: 10.18632/oncotarget.23680. eCollection 2018 Jan 19.

6.

Consecutive epigenetically-active agent combinations act in ID1-RUNX3-TET2 and HOXA pathways for Flt3ITD+ve AML.

Sayar H, Liu Y, Gao R, Zaid MA, Cripe LD, Weisenbach J, Sargent KJ, Nassiri M, Li L, Konig H, Suvannasankha A, Pan F, Shanmugam R, Goswami C, Kapur R, Xu M, Boswell HS.

Oncotarget. 2017 Dec 25;9(5):5703-5715. doi: 10.18632/oncotarget.23655. eCollection 2018 Jan 19.

7.

AR Expression in Breast Cancer CTCs Associates with Bone Metastases.

Aceto N, Bardia A, Wittner BS, Donaldson MC, O'Keefe R, Engstrom A, Bersani F, Zheng Y, Comaills V, Niederhoffer K, Zhu H, Mackenzie O, Shioda T, Sgroi D, Kapur R, Ting DT, Moy B, Ramaswamy S, Toner M, Haber DA, Maheswaran S.

Mol Cancer Res. 2018 Apr;16(4):720-727. doi: 10.1158/1541-7786.MCR-17-0480. Epub 2018 Feb 16.

PMID:
29453314
8.

Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy.

Hong X, Sullivan RJ, Kalinich M, Kwan TT, Giobbie-Hurder A, Pan S, LiCausi JA, Milner JD, Nieman LT, Wittner BS, Ho U, Chen T, Kapur R, Lawrence DP, Flaherty KT, Sequist LV, Ramaswamy S, Miyamoto DT, Lawrence M, Toner M, Isselbacher KJ, Maheswaran S, Haber DA.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2467-2472. doi: 10.1073/pnas.1719264115. Epub 2018 Feb 16.

9.

Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal brain.

Adams Waldorf KM, Nelson BR, Stencel-Baerenwald JE, Studholme C, Kapur RP, Armistead B, Walker CL, Merillat S, Vornhagen J, Tisoncik-Go J, Baldessari A, Coleman M, Dighe MK, Shaw DWW, Roby JA, Santana-Ufret V, Boldenow E, Li J, Gao X, Davis MA, Swanstrom JA, Jensen K, Widman DG, Baric RS, Medwid JT, Hanley KA, Ogle J, Gough GM, Lee W, English C, Durning WM, Thiel J, Gatenby C, Dewey EC, Fairgrieve MR, Hodge RD, Grant RF, Kuller L, Dobyns WB, Hevner RF, Gale M Jr, Rajagopal L.

Nat Med. 2018 Mar;24(3):368-374. doi: 10.1038/nm.4485. Epub 2018 Feb 5.

PMID:
29400709
10.

Targeting Transfusion-Related Acute Lung Injury: The Journey From Basic Science to Novel Therapies.

Semple JW, McVey MJ, Kim M, Rebetz J, Kuebler WM, Kapur R.

Crit Care Med. 2018 May;46(5):e452-e458. doi: 10.1097/CCM.0000000000002989.

PMID:
29384784
11.

An RNA-Based Digital Circulating Tumor Cell Signature Is Predictive of Drug Response and Early Dissemination in Prostate Cancer.

Miyamoto DT, Lee RJ, Kalinich M, LiCausi JA, Zheng Y, Chen T, Milner JD, Emmons E, Ho U, Broderick K, Silva E, Javaid S, Kwan TT, Hong X, Dahl DM, McGovern FJ, Efstathiou JA, Smith MR, Sequist LV, Kapur R, Wu CL, Stott SL, Ting DT, Giobbie-Hurder A, Toner M, Maheswaran S, Haber DA.

Cancer Discov. 2018 Mar;8(3):288-303. doi: 10.1158/2159-8290.CD-16-1406. Epub 2018 Jan 4.

PMID:
29301747
12.

Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets.

Zufferey A, Speck ER, Machlus KR, Aslam R, Guo L, McVey MJ, Kim M, Kapur R, Boilard E, Italiano JE Jr, Semple JW.

Blood Adv. 2017 Sep 8;1(20):1773-1785. doi: 10.1182/bloodadvances.2017007021. eCollection 2017 Sep 12.

13.

The mirn23a and mirn23b microrna clusters are necessary for proper hematopoietic progenitor cell production and differentiation.

Kurkewich JL, Boucher A, Klopfenstein N, Baskar R, Kapur R, Dahl R.

Exp Hematol. 2018 Mar;59:14-29. doi: 10.1016/j.exphem.2017.12.007. Epub 2017 Dec 27.

PMID:
29288704
14.

Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53.

Chen S, Gao R, Yao C, Kobayashi M, Liu SZ, Yoder MC, Broxmeyer H, Kapur R, Boswell HS, Mayo LD, Liu Y.

Leukemia. 2018 Mar;32(3):850-854. doi: 10.1038/leu.2017.325. Epub 2017 Nov 16. No abstract available.

15.

VACTERL phenotype with mosaic trisomy 5 and uniparental disomy 5.

Hwang S, Rudd MK, Finch L, Peterson SE, Kapur RP.

Am J Med Genet A. 2018 Feb;176(2):502-504. doi: 10.1002/ajmg.a.38579. Epub 2017 Dec 18. No abstract available.

PMID:
29250894
16.

Pharmacologic inhibition of PI3K p110δ in mutant Shp2E76K-expressing mice.

Deng L, Virts EL, Kapur R, Chan RJ.

Oncotarget. 2017 Oct 3;8(49):84776-84781. doi: 10.18632/oncotarget.21455. eCollection 2017 Oct 17.

17.

Colonic Adventitial Fibromuscular Dysplasia: A Nonspecific Arteriopathy Associated With Hirschsprung Disease and Other Obstructive Disorders.

Thaker AI, Kapur RP.

Pediatr Dev Pathol. 2017 Jan 1:1093526617739772. doi: 10.1177/1093526617739772. [Epub ahead of print]

PMID:
29108502
18.

A highly purified form of staphylococcal protein A alleviates murine immune thrombocytopenia (ITP).

Kapur R, Catalina MD, Aslam R, Speck ER, Francovitch RF, Semple JW.

Br J Haematol. 2017 Oct 19. doi: 10.1111/bjh.14985. [Epub ahead of print] No abstract available.

PMID:
29048127
19.

Specifically differentiated T cell subset promotes tumor immunity over fatal immunity.

Ramadan A, Griesenauer B, Adom D, Kapur R, Hanenberg H, Liu C, Kaplan MH, Paczesny S.

J Exp Med. 2017 Dec 4;214(12):3577-3596. doi: 10.1084/jem.20170041. Epub 2017 Oct 16.

20.

Differential regulation of two FLNA transcripts explains some of the phenotypic heterogeneity in the loss-of-function filaminopathies.

Jenkins ZA, Macharg A, Chang CY, van Kogelenberg M, Morgan T, Frentz S, Wei W, Pilch J, Hannibal M, Foulds N, McGillivray G, Leventer RJ, García-Miñaúr S, Sugito S, Nightingale S, Markie DM, Dudding T, Kapur RP, Robertson SP.

Hum Mutat. 2018 Jan;39(1):103-113. doi: 10.1002/humu.23355. Epub 2017 Nov 2.

PMID:
29024177
21.

Infection and Erosion Rates in Trials of a Cranially Implanted Neurostimulator Do Not Increase with Subsequent Neurostimulator Placements.

Weber PB, Kapur R, Gwinn RP, Zimmerman RS, Courtney TA, Morrell MJ.

Stereotact Funct Neurosurg. 2017;95(5):325-329. doi: 10.1159/000479288. Epub 2017 Sep 15.

22.

Prevalence and associated Risk Factors of Severe Early Childhood Caries in 12- to 36-month-old Children of Sirmaur District, Himachal Pradesh, India.

G Mangla R, Kapur R, Dhindsa A, Madan M.

Int J Clin Pediatr Dent. 2017 Apr-Jun;10(2):183-187. doi: 10.5005/jp-journals-10005-1431. Epub 2017 Jun 1.

23.

Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells.

Fachin F, Spuhler P, Martel-Foley JM, Edd JF, Barber TA, Walsh J, Karabacak M, Pai V, Yu M, Smith K, Hwang H, Yang J, Shah S, Yarmush R, Sequist LV, Stott SL, Maheswaran S, Haber DA, Kapur R, Toner M.

Sci Rep. 2017 Sep 7;7(1):10936. doi: 10.1038/s41598-017-11119-x.

24.

Low levels of interleukin-10 in patients with transfusion-related acute lung injury.

Kapur R, Kim M, Rebetz J, Rondina MT, Porcelijn L, Semple JW.

Ann Transl Med. 2017 Aug;5(16):339. doi: 10.21037/atm.2017.04.37. No abstract available.

25.

Non-equilibrium Inertial Separation Array for High-throughput, Large-volume Blood Fractionation.

Mutlu BR, Smith KC, Edd JF, Nadar P, Dlamini M, Kapur R, Toner M.

Sci Rep. 2017 Aug 30;7(1):9915. doi: 10.1038/s41598-017-10295-0.

26.

Kinase inhibitors in clinical practice: An expanding world.

Pandey R, Kapur R.

J Allergy Clin Immunol. 2018 Feb;141(2):522-524. doi: 10.1016/j.jaci.2017.07.016. Epub 2017 Aug 8. No abstract available.

27.

Paroxysmal Atrial Fibrillation due to Venomous Snake Bite.

Virmani S, Bhat R, Rao R, Kapur R, Dsouza S.

J Clin Diagn Res. 2017 Jun;11(6):OD01-OD02. doi: 10.7860/JCDR/2017/27553.9971. Epub 2017 Jun 1.

28.

Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells.

Metts J, Bradley HL, Wang Z, Shah NP, Kapur R, Arbiser JL, Bunting KD.

Sci Rep. 2017 Jun 30;7(1):4447. doi: 10.1038/s41598-017-04796-1.

29.

Choline Transporter Immunohistochemistry: An Effective Substitute for Acetylcholinesterase Histochemistry to Diagnose Hirschsprung Disease With Formalin-fixed Paraffin-embedded Rectal Biopsies.

Kapur RP, Raess PW, Hwang S, Winter C.

Pediatr Dev Pathol. 2017 Jul-Aug;20(4):308-320. doi: 10.1177/1093526617697060. Epub 2017 Mar 23.

PMID:
28649946
30.

Impact of hypoglycaemia on patient-reported outcomes from a global, 24-country study of 27,585 people with type 1 and insulin-treated type 2 diabetes.

Khunti K, Alsifri S, Aronson R, Cigrovski Berković M, Enters-Weijnen C, Forsén T, Galstyan G, Geelhoed-Duijvestijn P, Goldfracht M, Gydesen H, Kapur R, Lalic N, Ludvik B, Moberg E, Pedersen-Bjergaard U, Ramachandran A; HAT Investigator Group.

Diabetes Res Clin Pract. 2017 Aug;130:121-129. doi: 10.1016/j.diabres.2017.05.004. Epub 2017 May 12.

31.

Microfluidic Isolation of Circulating Tumor Cell Clusters by Size and Asymmetry.

Au SH, Edd J, Stoddard AE, Wong KHK, Fachin F, Maheswaran S, Haber DA, Stott SL, Kapur R, Toner M.

Sci Rep. 2017 May 26;7(1):2433. doi: 10.1038/s41598-017-01150-3.

32.

LIM kinases: cofilin and beyond.

Prunier C, Prudent R, Kapur R, Sadoul K, Lafanechère L.

Oncotarget. 2017 Jun 20;8(25):41749-41763. doi: 10.18632/oncotarget.16978. Review.

33.

Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis.

Kulkarni S, Micci MA, Leser J, Shin C, Tang SC, Fu YY, Liu L, Li Q, Saha M, Li C, Enikolopov G, Becker L, Rakhilin N, Anderson M, Shen X, Dong X, Butte MJ, Song H, Southard-Smith EM, Kapur RP, Bogunovic M, Pasricha PJ.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):E3709-E3718. doi: 10.1073/pnas.1619406114. Epub 2017 Apr 18.

34.

Brain-responsive neurostimulation in patients with medically intractable seizures arising from eloquent and other neocortical areas.

Jobst BC, Kapur R, Barkley GL, Bazil CW, Berg MJ, Bergey GK, Boggs JG, Cash SS, Cole AJ, Duchowny MS, Duckrow RB, Edwards JC, Eisenschenk S, Fessler AJ, Fountain NB, Geller EB, Goldman AM, Goodman RR, Gross RE, Gwinn RP, Heck C, Herekar AA, Hirsch LJ, King-Stephens D, Labar DR, Marsh WR, Meador KJ, Miller I, Mizrahi EM, Murro AM, Nair DR, Noe KH, Olejniczak PW, Park YD, Rutecki P, Salanova V, Sheth RD, Skidmore C, Smith MC, Spencer DC, Srinivasan S, Tatum W, Van Ness P, Vossler DG, Wharen RE Jr, Worrell GA, Yoshor D, Zimmerman RS, Skarpaas TL, Morrell MJ.

Epilepsia. 2017 Jun;58(6):1005-1014. doi: 10.1111/epi.13739. Epub 2017 Apr 7.

35.

DPP4 truncated GM-CSF and IL-3 manifest distinct receptor-binding and regulatory functions compared with their full-length forms.

O'Leary HA, Capitano M, Cooper S, Mantel C, Boswell HS, Kapur R, Ramdas B, Chan R, Deng L, Qu CK, Broxmeyer HE.

Leukemia. 2017 Nov;31(11):2468-2478. doi: 10.1038/leu.2017.98. Epub 2017 Mar 27.

36.

Focal Brain Injury Associated with a Model of Severe Hypoxic-Ischemic Encephalopathy in Nonhuman Primates.

McAdams RM, McPherson RJ, Kapur RP, Juul SE.

Dev Neurosci. 2017;39(1-4):107-123. doi: 10.1159/000456658. Epub 2017 Mar 25.

37.

Role of mTORC1-S6K1 signaling pathway in regulation of hematopoietic stem cell and acute myeloid leukemia.

Ghosh J, Kapur R.

Exp Hematol. 2017 Jun;50:13-21. doi: 10.1016/j.exphem.2017.02.004. Epub 2017 Mar 22. Review.

38.

Role of SHP2 in hematopoiesis and leukemogenesis.

Pandey R, Saxena M, Kapur R.

Curr Opin Hematol. 2017 Jul;24(4):307-313. doi: 10.1097/MOH.0000000000000345. Review.

39.

Phosphatase PRL2 promotes AML1-ETO-induced acute myeloid leukemia.

Kobayashi M, Chen S, Bai Y, Yao C, Gao R, Sun XJ, Mu C, Twiggs TA, Yu ZH, Boswell HS, Yoder MC, Kapur R, Mulloy JC, Zhang ZY, Liu Y.

Leukemia. 2017 Jun;31(6):1453-1457. doi: 10.1038/leu.2017.67. Epub 2017 Feb 21. No abstract available.

40.

Pathogenesis and Therapeutic Mechanisms in  Immune Thrombocytopenia (ITP).

Zufferey A, Kapur R, Semple JW.

J Clin Med. 2017 Feb 9;6(2). pii: E16. doi: 10.3390/jcm6020016. Review.

41.

T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10.

Kapur R, Kim M, Aslam R, McVey MJ, Tabuchi A, Luo A, Liu J, Li Y, Shanmugabhavananthan S, Speck ER, Zufferey A, Yousef G, Zhang H, Rondina MT, Weyrich AS, Porcelijn L, Kuebler WM, Slutsky AS, Semple JW.

Blood. 2017 May 4;129(18):2557-2569. doi: 10.1182/blood-2016-12-758185. Epub 2017 Feb 15.

42.

Guidelines for the management of postoperative obstructive symptoms in children with Hirschsprung disease.

Langer JC, Rollins MD, Levitt M, Gosain A, Torre L, Kapur RP, Cowles RA, Horton J, Rothstein DH, Goldstein AM; American Pediatric Surgical Association Hirschsprung Disease Interest Group.

Pediatr Surg Int. 2017 May;33(5):523-526. doi: 10.1007/s00383-017-4066-7. Epub 2017 Feb 8. Review.

PMID:
28180937
43.

p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation.

Hinge A, Xu J, Javier J, Mose E, Kumar S, Kapur R, Srour EF, Malik P, Aronow BJ, Filippi MD.

Nat Commun. 2017 Feb 8;8:14382. doi: 10.1038/ncomms14382.

44.

Alleviation of gram-negative bacterial lung inflammation by targeting HECTD2.

Kapur R, Semple JW.

Ann Transl Med. 2016 Dec;4(24):488. doi: 10.21037/atm.2016.11.41. No abstract available.

45.

Feasibility of detecting orthopaedic screw overtightening using acoustic emission.

Pullin R, Wright BJ, Kapur R, McCrory JP, Pearson M, Evans SL, Crivelli D.

Proc Inst Mech Eng H. 2017 Mar;231(3):213-221. doi: 10.1177/0954411916689112. Epub 2017 Jan 24.

PMID:
28116977
46.

An RNA-based signature enables high specificity detection of circulating tumor cells in hepatocellular carcinoma.

Kalinich M, Bhan I, Kwan TT, Miyamoto DT, Javaid S, LiCausi JA, Milner JD, Hong X, Goyal L, Sil S, Choz M, Ho U, Kapur R, Muzikansky A, Zhang H, Weitz DA, Sequist LV, Ryan DP, Chung RT, Zhu AX, Isselbacher KJ, Ting DT, Toner M, Maheswaran S, Haber DA.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1123-1128. doi: 10.1073/pnas.1617032114. Epub 2017 Jan 17.

47.

Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors.

Kobayashi M, Nabinger SC, Bai Y, Yoshimoto M, Gao R, Chen S, Yao C, Dong Y, Zhang L, Rodriguez S, Yashiro-Ohtani Y, Pear WS, Carlesso N, Yoder MC, Kapur R, Kaplan MH, Daniel Lacorazza H, Zhang ZY, Liu Y.

Stem Cells. 2017 Apr;35(4):1053-1064. doi: 10.1002/stem.2559. Epub 2017 Jan 19.

48.

Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia.

Kapur R, Aslam R, Kim M, Guo L, Ni H, Segel GB, Semple JW.

Platelets. 2017 Jul;28(5):521-524. doi: 10.1080/09537104.2016.1246718. Epub 2016 Nov 25.

PMID:
27885866
49.

Platelets as immune-sensing cells.

Kapur R, Semple JW.

Blood Adv. 2016 Nov 22;1(1):10-14. doi: 10.1182/bloodadvances.2016000067. eCollection 2016 Nov 29.

50.

Acoustic emission in orthopaedics: A state of the art review.

Kapur RA.

J Biomech. 2016 Dec 8;49(16):4065-4072. doi: 10.1016/j.jbiomech.2016.10.038. Epub 2016 Oct 28. Review.

PMID:
27816181

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