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Items: 1 to 50 of 501

1.

SHP2 inhibition reduces leukemogenesis in models of combined genetic and epigenetic mutations.

Pandey R, Ramdas B, Wan C, Sandusky G, Mohseni M, Zhang C, Kapur R.

J Clin Invest. 2019 Nov 4. pii: 130520. doi: 10.1172/JCI130520. [Epub ahead of print]

2.

The Role of Complement in Transfusion-Related Acute Lung Injury.

Jongerius I, Porcelijn L, van Beek AE, Semple JW, van der Schoot CE, Vlaar APJ, Kapur R.

Transfus Med Rev. 2019 Oct 18. pii: S0887-7963(19)30130-0. doi: 10.1016/j.tmrv.2019.09.002. [Epub ahead of print] Review.

PMID:
31676221
3.

Promoter demethylation of the asparagine synthetase gene is required for an ATF4-dependent adaptation to asparagine depletion.

Jiang J, Srivastava S, Seim G, Pavlova NN, King B, Zou L, Zhang C, Zhong M, Feng H, Kapur R, Wek RC, Fan J, Zhang J.

J Biol Chem. 2019 Oct 28. pii: jbc.RA119.010447. doi: 10.1074/jbc.RA119.010447. [Epub ahead of print]

4.

Multimodality and multiterritory vascular imaging in a toddler with acquired, complex, and unusual aortic arch anatomy.

Bhat AH, Trent E, Kapur RP, Permut L.

Echocardiography. 2019 Oct;36(10):1947-1951. doi: 10.1111/echo.14475. Epub 2019 Sep 6.

PMID:
31490577
5.

Treating murine inflammatory diseases with an anti-erythrocyte antibody.

Crow AR, Kapur R, Koernig S, Campbell IK, Jen CC, Mott PJ, Marjoram D, Khan R, Kim M, Brasseit J, Cruz-Leal Y, Amash A, Kahlon S, Yougbare I, Ni H, Zuercher AW, Käsermann F, Semple JW, Lazarus AH.

Sci Transl Med. 2019 Aug 21;11(506). pii: eaau8217. doi: 10.1126/scitranslmed.aau8217.

PMID:
31434758
6.

Transfusion-related Acute Lung Injury in the Perioperative Patient.

McVey MJ, Kapur R, Cserti-Gazdewich C, Semple JW, Karkouti K, Kuebler WM.

Anesthesiology. 2019 Sep;131(3):693-715. doi: 10.1097/ALN.0000000000002687.

PMID:
31408449
7.

The Personalized Parkinson Project: examining disease progression through broad biomarkers in early Parkinson's disease.

Bloem BR, Marks WJ Jr, Silva de Lima AL, Kuijf ML, van Laar T, Jacobs BPF, Verbeek MM, Helmich RC, van de Warrenburg BP, Evers LJW, intHout J, van de Zande T, Snyder TM, Kapur R, Meinders MJ.

BMC Neurol. 2019 Jul 17;19(1):160. doi: 10.1186/s12883-019-1394-3.

8.

Anti-glycoprotein Ibα autoantibodies do not impair circulating thrombopoietin levels in immune thrombocytopenia patients.

Porcelijn L, Schmidt DE, van der Schoot CE, Vidarsson G, de Haas M, Kapur R.

Haematologica. 2019 Jul 11. pii: haematol.2019.228908. doi: 10.3324/haematol.2019.228908. [Epub ahead of print]

9.

The fetal origins of mental illness.

Al-Haddad BJS, Oler E, Armistead B, Elsayed NA, Weinberger DR, Bernier R, Burd I, Kapur R, Jacobsson B, Wang C, Mysorekar I, Rajagopal L, Adams Waldorf KM.

Am J Obstet Gynecol. 2019 Jun 15. pii: S0002-9378(19)30777-X. doi: 10.1016/j.ajog.2019.06.013. [Epub ahead of print] Review.

PMID:
31207234
10.

Thrombopoietin receptor agonist (TPO-RA) treatment raises platelet counts and reduces anti-platelet antibody levels in mice with immune thrombocytopenia (ITP).

Kapur R, Aslam R, Speck ER, Rebetz JM, Semple JW.

Platelets. 2019 May 30:1-4. doi: 10.1080/09537104.2019.1624709. [Epub ahead of print]

PMID:
31146647
11.

Osteopontin mediates murine transfusion-related acute lung injury via stimulation of pulmonary neutrophil accumulation.

Kapur R, Kasetty G, Rebetz J, Egesten A, Semple JW.

Blood. 2019 Jul 4;134(1):74-84. doi: 10.1182/blood.2019000972. Epub 2019 May 10.

PMID:
31076444
12.

Guidelines for synoptic reporting of surgery and pathology in Hirschsprung disease.

Veras LV, Arnold M, Avansino JR, Bove K, Cowles RA, Durham MM, Goldstein AM, Krishnan C, Langer JC, Levitt M, Monforte-Munoz H, Rabah R, Reyes-Mugica M, Rollins MD 2nd, Kapur RP, Gosain A; American Pediatric Surgical Association Hirschsprung Disease Interest Group.

J Pediatr Surg. 2019 Oct;54(10):2017-2023. doi: 10.1016/j.jpedsurg.2019.03.010. Epub 2019 Mar 21. Review.

PMID:
30935730
13.

Infra-anastomotic Innervation of Residual Aganglionic Distal Rectum After Pull-through Surgery for Hirschsprung Disease.

Kapur RP, Arnold MA, Conces MR.

Pediatr Dev Pathol. 2019 Oct;22(5):420-430. doi: 10.1177/1093526619837788. Epub 2019 Mar 27.

PMID:
30915893
14.

Community-based testing of migrants for infectious diseases (COMBAT-ID): impact, acceptability and cost-effectiveness of identifying infectious diseases among migrants in primary care: protocol for an interrupted time-series, qualitative and health economic analysis.

Pareek M, Eborall HC, Wobi F, Ellis KS, Kontopantelis E, Zhang F, Baggaley R, Hollingsworth TD, Baines D, Patel H, Haldar P, Patel M, Stephenson I, Browne I, Gill P, Kapur R, Farooqi A, Abubakar I, Griffiths C.

BMJ Open. 2019 Mar 7;9(3):e029188. doi: 10.1136/bmjopen-2019-029188.

15.

Transfusion-associated circulatory overload and transfusion-related acute lung injury.

Semple JW, Rebetz J, Kapur R.

Blood. 2019 Apr 25;133(17):1840-1853. doi: 10.1182/blood-2018-10-860809. Epub 2019 Feb 26. Review.

PMID:
30808638
16.

Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation.

Garg G, Muschaweckh A, Moreno H, Vasanthakumar A, Floess S, Lepennetier G, Oellinger R, Zhan Y, Regen T, Hiltensperger M, Peter C, Aly L, Knier B, Palam LR, Kapur R, Kaplan MH, Waisman A, Rad R, Schotta G, Huehn J, Kallies A, Korn T.

Cell Rep. 2019 Feb 12;26(7):1854-1868.e5. doi: 10.1016/j.celrep.2019.01.070.

17.

The Ultimate Murine Model of Immune Thrombocytopaenia.

Semple JW, Kapur R.

Thromb Haemost. 2019 Mar;119(3):353-354. doi: 10.1055/s-0039-1678697. Epub 2019 Feb 6.

PMID:
30727005
18.

Mutant p53 enhances leukemia-initiating cell self-renewal to promote leukemia development.

Nabinger SC, Chen S, Gao R, Yao C, Kobayashi M, Vemula S, Fahey AC, Wang C, Daniels C, Boswell HS, Sandusky GE, Mayo LD, Kapur R, Liu Y.

Leukemia. 2019 Jun;33(6):1535-1539. doi: 10.1038/s41375-019-0377-0. Epub 2019 Jan 23. No abstract available.

PMID:
30675010
19.

A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1.

Prudent R, Demoncheaux N, Diemer H, Collin-Faure V, Kapur R, Paublant F, Lafanechère L, Cianférani S, Rabilloud T.

PLoS One. 2018 Dec 14;13(12):e0208979. doi: 10.1371/journal.pone.0208979. eCollection 2018.

20.

Remodeling of Rectal Innervation After Pullthrough Surgery for Hirschsprung Disease: Relevance to Criteria for the Determination of Retained Transition Zone.

Kapur RP, Arnold MA, Conces MR, Ambartsumyan L, Avansino J, Levitt M, Wood R, Mast KJ.

Pediatr Dev Pathol. 2019 Jul-Aug;22(4):292-303. doi: 10.1177/1093526618817658. Epub 2018 Dec 12.

PMID:
30541422
21.

Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis.

Cai Z, Kotzin JJ, Ramdas B, Chen S, Nelanuthala S, Palam LR, Pandey R, Mali RS, Liu Y, Kelley MR, Sandusky G, Mohseni M, Williams A, Henao-Mejia J, Kapur R.

Cell Stem Cell. 2018 Dec 6;23(6):833-849.e5. doi: 10.1016/j.stem.2018.10.013.

PMID:
30526882
22.

The Pathogenic Involvement of Neutrophils in Acute Respiratory Distress Syndrome and Transfusion-Related Acute Lung Injury.

Rebetz J, Semple JW, Kapur R.

Transfus Med Hemother. 2018 Oct;45(5):290-298. doi: 10.1159/000492950. Epub 2018 Sep 21. Review.

23.

Atypical Hepatic Mesenchymal Hamartoma: Histologic Appearance, Immunophenotype, and Molecular Findings.

El Demellawy D, Lee JY, McDonell L, Dyment DA, Knisely AS, McGowan-Jordan J, Ngan B, Finegold M, Kapur RP, Nasr A.

Pediatr Dev Pathol. 2019 Jul-Aug;22(4):365-369. doi: 10.1177/1093526618806750. Epub 2018 Nov 29.

PMID:
30497332
24.

On-chip oocyte denudation from cumulus-oocyte complexes for assisted reproductive therapy.

Weng L, Lee GY, Liu J, Kapur R, Toth TL, Toner M.

Lab Chip. 2018 Dec 4;18(24):3892-3902. doi: 10.1039/c8lc01075g.

PMID:
30465050
25.

Fatal enteric plexus neuropathy after one dose of ipilimumab plus nivolumab: a case report.

Appelbaum J, Wells D, Hiatt JB, Steinbach G, Stewart FM, Thomas H, Nghiem P, Kapur RP, Thompson JA, Bhatia S.

J Immunother Cancer. 2018 Aug 31;6(1):82. doi: 10.1186/s40425-018-0396-9.

26.

Anaesthetic management for cardiac surgery in patients with cold haemagglutinin disease.

Khanuja JS, Aggarwal N, Kapur R, Srivastava S.

Indian J Anaesth. 2018 Aug;62(8):628-631. doi: 10.4103/ija.IJA_264_18.

27.

P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim.

Hu P, Nebreda AR, Hanenberg H, Kinnebrew GH, Ivan M, Yoder MC, Filippi MD, Broxmeyer HE, Kapur R.

Nat Commun. 2018 Aug 29;9(1):3518. doi: 10.1038/s41467-018-05955-2.

28.

Moving target PF4 directs HIT responses.

Semple JW, Kapur R.

Blood. 2018 Aug 16;132(7):678-679. doi: 10.1182/blood-2018-07-859975. No abstract available.

PMID:
30115634
29.

A Digital RNA Signature of Circulating Tumor Cells Predicting Early Therapeutic Response in Localized and Metastatic Breast Cancer.

Kwan TT, Bardia A, Spring LM, Giobbie-Hurder A, Kalinich M, Dubash T, Sundaresan T, Hong X, LiCausi JA, Ho U, Silva EJ, Wittner BS, Sequist LV, Kapur R, Miyamoto DT, Toner M, Haber DA, Maheswaran S.

Cancer Discov. 2018 Oct;8(10):1286-1299. doi: 10.1158/2159-8290.CD-18-0432. Epub 2018 Aug 13.

30.

Intestinal Neuronal Dysplasia Type B: An Updated Review of a Problematic Diagnosis.

Kapur RP, Reyes-Mugica M.

Arch Pathol Lab Med. 2019 Feb;143(2):235-243. doi: 10.5858/arpa.2017-0524-RA. Epub 2018 Aug 8.

PMID:
30088780
31.

Characterization of leaf transcriptome, development and utilization of unigenes-derived microsatellite markers in sugarcane (Saccharum sp. hybrid).

Khan MS, Kumar S, Singh RK, Singh J, Duttamajumder SK, Kapur R.

Physiol Mol Biol Plants. 2018 Jul;24(4):665-682. doi: 10.1007/s12298-018-0563-y. Epub 2018 Jun 4.

32.

Gastrointestinal microbiota contributes to the development of murine transfusion-related acute lung injury.

Kapur R, Kim M, Rebetz J, Hallström B, Björkman JT, Takabe-French A, Kim N, Liu J, Shanmugabhavananthan S, Milosevic S, McVey MJ, Speck ER, Semple JW.

Blood Adv. 2018 Jul 10;2(13):1651-1663. doi: 10.1182/bloodadvances.2018018903.

33.

Antiplatelet antibody-induced thrombocytopenia does not correlate with megakaryocyte abnormalities in murine immune thrombocytopenia.

Guo L, Kapur R, Aslam R, Hunt K, Hou Y, Zufferey A, Speck ER, Rondina MT, Lazarus AH, Ni H, Semple JW.

Scand J Immunol. 2018 Jul;88(1):e12678. doi: 10.1111/sji.12678.

34.

Parallel detection of lactobacillus and bacterial vaginosis-associated bacterial DNA in the chorioamnion and vagina of pregnant women at term.

Lannon SMR, Adams Waldorf KM, Fiedler T, Kapur RP, Agnew K, Rajagopal L, Gravett MG, Fredricks DN.

J Matern Fetal Neonatal Med. 2019 Aug;32(16):2702-2710. doi: 10.1080/14767058.2018.1446208. Epub 2018 Mar 12.

PMID:
29478370
35.

Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway.

Palam LR, Mali RS, Ramdas B, Srivatsan SN, Visconte V, Tiu RV, Vanhaesebroeck B, Roers A, Gerbaulet A, Xu M, Janga SC, Takemoto CM, Paczesny S, Kapur R.

JCI Insight. 2018 Feb 22;3(4). pii: 94679. doi: 10.1172/jci.insight.94679. eCollection 2018 Feb 22.

36.

Rapid development of myeloproliferative neoplasm in mice with Ptpn11D61Y mutation and haploinsufficient for Dnmt3a.

Deng L, Richine BM, Virts EL, Jideonwo-Auman VN, Chan RJ, Kapur R.

Oncotarget. 2017 Dec 26;9(5):6055-6061. doi: 10.18632/oncotarget.23680. eCollection 2018 Jan 19.

37.

Consecutive epigenetically-active agent combinations act in ID1-RUNX3-TET2 and HOXA pathways for Flt3ITD+ve AML.

Sayar H, Liu Y, Gao R, Zaid MA, Cripe LD, Weisenbach J, Sargent KJ, Nassiri M, Li L, Konig H, Suvannasankha A, Pan F, Shanmugam R, Goswami C, Kapur R, Xu M, Boswell HS.

Oncotarget. 2017 Dec 25;9(5):5703-5715. doi: 10.18632/oncotarget.23655. eCollection 2018 Jan 19.

38.

AR Expression in Breast Cancer CTCs Associates with Bone Metastases.

Aceto N, Bardia A, Wittner BS, Donaldson MC, O'Keefe R, Engstrom A, Bersani F, Zheng Y, Comaills V, Niederhoffer K, Zhu H, Mackenzie O, Shioda T, Sgroi D, Kapur R, Ting DT, Moy B, Ramaswamy S, Toner M, Haber DA, Maheswaran S.

Mol Cancer Res. 2018 Apr;16(4):720-727. doi: 10.1158/1541-7786.MCR-17-0480. Epub 2018 Feb 16.

39.

Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy.

Hong X, Sullivan RJ, Kalinich M, Kwan TT, Giobbie-Hurder A, Pan S, LiCausi JA, Milner JD, Nieman LT, Wittner BS, Ho U, Chen T, Kapur R, Lawrence DP, Flaherty KT, Sequist LV, Ramaswamy S, Miyamoto DT, Lawrence M, Toner M, Isselbacher KJ, Maheswaran S, Haber DA.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2467-2472. doi: 10.1073/pnas.1719264115. Epub 2018 Feb 16.

40.

Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal brain.

Adams Waldorf KM, Nelson BR, Stencel-Baerenwald JE, Studholme C, Kapur RP, Armistead B, Walker CL, Merillat S, Vornhagen J, Tisoncik-Go J, Baldessari A, Coleman M, Dighe MK, Shaw DWW, Roby JA, Santana-Ufret V, Boldenow E, Li J, Gao X, Davis MA, Swanstrom JA, Jensen K, Widman DG, Baric RS, Medwid JT, Hanley KA, Ogle J, Gough GM, Lee W, English C, Durning WM, Thiel J, Gatenby C, Dewey EC, Fairgrieve MR, Hodge RD, Grant RF, Kuller L, Dobyns WB, Hevner RF, Gale M Jr, Rajagopal L.

Nat Med. 2018 Mar;24(3):368-374. doi: 10.1038/nm.4485. Epub 2018 Feb 5.

41.

Targeting Transfusion-Related Acute Lung Injury: The Journey From Basic Science to Novel Therapies.

Semple JW, McVey MJ, Kim M, Rebetz J, Kuebler WM, Kapur R.

Crit Care Med. 2018 May;46(5):e452-e458. doi: 10.1097/CCM.0000000000002989. Review.

PMID:
29384784
42.

An RNA-Based Digital Circulating Tumor Cell Signature Is Predictive of Drug Response and Early Dissemination in Prostate Cancer.

Miyamoto DT, Lee RJ, Kalinich M, LiCausi JA, Zheng Y, Chen T, Milner JD, Emmons E, Ho U, Broderick K, Silva E, Javaid S, Kwan TT, Hong X, Dahl DM, McGovern FJ, Efstathiou JA, Smith MR, Sequist LV, Kapur R, Wu CL, Stott SL, Ting DT, Giobbie-Hurder A, Toner M, Maheswaran S, Haber DA.

Cancer Discov. 2018 Mar;8(3):288-303. doi: 10.1158/2159-8290.CD-16-1406. Epub 2018 Jan 4.

43.

Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets.

Zufferey A, Speck ER, Machlus KR, Aslam R, Guo L, McVey MJ, Kim M, Kapur R, Boilard E, Italiano JE Jr, Semple JW.

Blood Adv. 2017 Sep 8;1(20):1773-1785. doi: 10.1182/bloodadvances.2017007021. eCollection 2017 Sep 12.

44.

The mirn23a and mirn23b microrna clusters are necessary for proper hematopoietic progenitor cell production and differentiation.

Kurkewich JL, Boucher A, Klopfenstein N, Baskar R, Kapur R, Dahl R.

Exp Hematol. 2018 Mar;59:14-29. doi: 10.1016/j.exphem.2017.12.007. Epub 2017 Dec 27.

45.

Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53.

Chen S, Gao R, Yao C, Kobayashi M, Liu SZ, Yoder MC, Broxmeyer H, Kapur R, Boswell HS, Mayo LD, Liu Y.

Leukemia. 2018 Mar;32(3):850-854. doi: 10.1038/leu.2017.325. Epub 2017 Nov 16. No abstract available.

46.

VACTERL phenotype with mosaic trisomy 5 and uniparental disomy 5.

Hwang S, Rudd MK, Finch L, Peterson SE, Kapur RP.

Am J Med Genet A. 2018 Feb;176(2):502-504. doi: 10.1002/ajmg.a.38579. Epub 2017 Dec 18. No abstract available.

PMID:
29250894
47.

Pharmacologic inhibition of PI3K p110δ in mutant Shp2E76K-expressing mice.

Deng L, Virts EL, Kapur R, Chan RJ.

Oncotarget. 2017 Oct 3;8(49):84776-84781. doi: 10.18632/oncotarget.21455. eCollection 2017 Oct 17.

48.

Colonic Adventitial Fibromuscular Dysplasia: A Nonspecific Arteriopathy Associated With Hirschsprung Disease and Other Obstructive Disorders.

Thaker AI, Kapur RP.

Pediatr Dev Pathol. 2018 Jul-Aug;21(4):363-370. doi: 10.1177/1093526617739772. Epub 2017 Nov 6.

PMID:
29108502
49.

A highly purified form of staphylococcal protein A alleviates murine immune thrombocytopenia (ITP).

Kapur R, Catalina MD, Aslam R, Speck ER, Francovitch RF, Semple JW.

Br J Haematol. 2018 Nov;183(3):501-503. doi: 10.1111/bjh.14985. Epub 2017 Oct 19. No abstract available.

PMID:
29048127
50.

Specifically differentiated T cell subset promotes tumor immunity over fatal immunity.

Ramadan A, Griesenauer B, Adom D, Kapur R, Hanenberg H, Liu C, Kaplan MH, Paczesny S.

J Exp Med. 2017 Dec 4;214(12):3577-3596. doi: 10.1084/jem.20170041. Epub 2017 Oct 16.

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