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Items: 1 to 50 of 143

1.

FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming.

Hoepel W, Newling M, Vogelpoel LTC, Sritharan L, Hansen IS, Kapsenberg ML, Baeten DLP, Everts B, den Dunnen J.

Front Immunol. 2019 Apr 8;10:739. doi: 10.3389/fimmu.2019.00739. eCollection 2019.

2.

Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells.

Newling M, Hoepel W, Vogelpoel LTC, Heineke MH, van Burgsteden JA, Taanman-Kueter EWM, Eggink D, Kuijpers TW, Beaumont T, van Egmond M, Kapsenberg ML, Baeten DLP, den Dunnen J, Jong EC.

Eur J Immunol. 2018 Nov;48(11):1796-1809. doi: 10.1002/eji.201847615. Epub 2018 Sep 14.

3.

Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages.

Vogelpoel LT, Hansen IS, Rispens T, Muller FJ, van Capel TM, Turina MC, Vos JB, Baeten DL, Kapsenberg ML, de Jong EC, den Dunnen J.

Nat Commun. 2014 Nov 13;5:5444. doi: 10.1038/ncomms6444.

4.

Vitamin D3 metabolite calcidiol primes human dendritic cells to promote the development of immunomodulatory IL-10-producing T cells.

Bakdash G, van Capel TM, Mason LM, Kapsenberg ML, de Jong EC.

Vaccine. 2014 Oct 29;32(47):6294-302. doi: 10.1016/j.vaccine.2014.08.075. Epub 2014 Sep 16.

PMID:
25236584
5.

FcγRIIa cross-talk with TLRs, IL-1R, and IFNγR selectively modulates cytokine production in human myeloid cells.

Vogelpoel LT, Hansen IS, Visser MW, Nagelkerke SQ, Kuijpers TW, Kapsenberg ML, de Jong EC, den Dunnen J.

Immunobiology. 2015 Feb;220(2):193-9. doi: 10.1016/j.imbio.2014.07.016. Epub 2014 Jul 25.

PMID:
25108563
6.

Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells.

Bakdash G, Vogelpoel LT, van Capel TM, Kapsenberg ML, de Jong EC.

Mucosal Immunol. 2015 Mar;8(2):265-78. doi: 10.1038/mi.2014.64. Epub 2014 Jul 16.

PMID:
25027601
7.

Langerhans cells favor skin flora tolerance through limited presentation of bacterial antigens and induction of regulatory T cells.

van der Aar AM, Picavet DI, Muller FJ, de Boer L, van Capel TM, Zaat SA, Bos JD, Janssen H, George TC, Kapsenberg ML, van Ham SM, Teunissen MB, de Jong EC.

J Invest Dermatol. 2013 May;133(5):1240-9. doi: 10.1038/jid.2012.500. Epub 2013 Feb 7.

8.

Intradermal application of vitamin D3 increases migration of CD14+ dermal dendritic cells and promotes the development of Foxp3+ regulatory T cells.

Bakdash G, Schneider LP, van Capel TM, Kapsenberg ML, Teunissen MB, de Jong EC.

Hum Vaccin Immunother. 2013 Feb;9(2):250-8. Epub 2013 Jan 4.

9.

Viral dsRNA-activated human dendritic cells produce IL-27, which selectively promotes cytotoxicity in naive CD8+ T cells.

de Groot R, van Beelen AJ, Bakdash G, Taanman-Kueter EW, de Jong EC, Kapsenberg ML.

J Leukoc Biol. 2012 Sep;92(3):605-10. doi: 10.1189/jlb.0112045. Epub 2012 Jun 13.

PMID:
22701040
10.

IgG opsonization of bacteria promotes Th17 responses via synergy between TLRs and FcγRIIa in human dendritic cells.

den Dunnen J, Vogelpoel LT, Wypych T, Muller FJ, de Boer L, Kuijpers TW, Zaat SA, Kapsenberg ML, de Jong EC.

Blood. 2012 Jul 5;120(1):112-21. doi: 10.1182/blood-2011-12-399931. Epub 2012 May 30.

PMID:
22649103
11.

CD5 costimulation induces stable Th17 development by promoting IL-23R expression and sustained STAT3 activation.

de Wit J, Souwer Y, van Beelen AJ, de Groot R, Muller FJ, Klaasse Bos H, Jorritsma T, Kapsenberg ML, de Jong EC, van Ham SM.

Blood. 2011 Dec 1;118(23):6107-14. doi: 10.1182/blood-2011-05-352682. Epub 2011 Sep 16.

PMID:
21926348
12.

Cutting edge: virus selectively primes human langerhans cells for CD70 expression promoting CD8+ T cell responses.

van der Aar AM, de Groot R, Sanchez-Hernandez M, Taanman EW, van Lier RA, Teunissen MB, de Jong EC, Kapsenberg ML.

J Immunol. 2011 Oct 1;187(7):3488-92. doi: 10.4049/jimmunol.1101105. Epub 2011 Aug 31.

13.

Genetically Modified Lactococcus lactis for Delivery of Human Interleukin-10 to Dendritic Cells.

Huibregtse IL, Zaat SA, Kapsenberg ML, Sartori da Silva MA, Peppelenbosch MP, van Deventer SJ, Braat H.

Gastroenterol Res Pract. 2012;2012:639291. doi: 10.1155/2012/639291. Epub 2011 Jul 27.

14.

Vitamin D3 targets epidermal and dermal dendritic cells for induction of distinct regulatory T cells.

van der Aar AM, Sibiryak DS, Bakdash G, van Capel TM, van der Kleij HP, Opstelten DJ, Teunissen MB, Kapsenberg ML, de Jong EC.

J Allergy Clin Immunol. 2011 Jun;127(6):1532-40.e7. doi: 10.1016/j.jaci.2011.01.068. Epub 2011 Apr 17.

PMID:
21497886
15.

IL-17 and IL-22 in atopic allergic disease.

Souwer Y, Szegedi K, Kapsenberg ML, de Jong EC.

Curr Opin Immunol. 2010 Dec;22(6):821-6. doi: 10.1016/j.coi.2010.10.013. Epub 2010 Nov 17. Review.

PMID:
21087848
16.

Gammadelta T cell receptors without a job.

Kapsenberg ML.

Immunity. 2009 Aug 21;31(2):181-3. doi: 10.1016/j.immuni.2009.08.004.

17.

Aberrant function of peripheral blood myeloid and plasmacytoid dendritic cells in atopic dermatitis patients.

Lebre MC, van Capel TM, Bos JD, Knol EF, Kapsenberg ML, de Jong EC.

J Allergy Clin Immunol. 2008 Nov;122(5):969-976.e5. doi: 10.1016/j.jaci.2008.08.028. Epub 2008 Oct 9.

PMID:
18845325
18.

Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells.

van Beelen AJ, Zelinkova Z, Taanman-Kueter EW, Muller FJ, Hommes DW, Zaat SA, Kapsenberg ML, de Jong EC.

Immunity. 2007 Oct;27(4):660-9. Epub 2007 Oct 4.

19.

Interleukin-17 in inflammatory skin disorders.

van Beelen AJ, Teunissen MB, Kapsenberg ML, de Jong EC.

Curr Opin Allergy Clin Immunol. 2007 Oct;7(5):374-81. Review.

PMID:
17873575
20.

Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation.

Tas SW, Vervoordeldonk MJ, Hajji N, Schuitemaker JH, van der Sluijs KF, May MJ, Ghosh S, Kapsenberg ML, Tak PP, de Jong EC.

Blood. 2007 Sep 1;110(5):1540-9. Epub 2007 May 4.

PMID:
17483297
21.

Future perspectives of novel immunomodulating substances in immunotherapy.

de Jong EC, Kapsenberg ML.

Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe Frankf A M. 2006;(95):207-10; discussion 210. No abstract available.

PMID:
17393741
22.

An improved protocol for generation of immuno-potent dendritic cells through direct electroporation of CD14+ monocytes.

Milano F, van Baal JW, Rygiel AM, Bergman JJ, Van Deventer SJ, Kapsenberg ML, Peppelenbosch MP, Krishnadath KK.

J Immunol Methods. 2007 Apr 10;321(1-2):94-106. Epub 2007 Feb 5.

PMID:
17336322
23.

Loss of TLR2, TLR4, and TLR5 on Langerhans cells abolishes bacterial recognition.

van der Aar AM, Sylva-Steenland RM, Bos JD, Kapsenberg ML, de Jong EC, Teunissen MB.

J Immunol. 2007 Feb 15;178(4):1986-90.

24.

Human keratinocytes express functional Toll-like receptor 3, 4, 5, and 9.

Lebre MC, van der Aar AM, van Baarsen L, van Capel TM, Schuitemaker JH, Kapsenberg ML, de Jong EC.

J Invest Dermatol. 2007 Feb;127(2):331-41. Epub 2006 Oct 26.

25.

Opposing roles of blood myeloid and plasmacytoid dendritic cells in HIV-1 infection of T cells: transmission facilitation versus replication inhibition.

Groot F, van Capel TM, Kapsenberg ML, Berkhout B, de Jong EC.

Blood. 2006 Sep 15;108(6):1957-64. Epub 2006 May 16.

PMID:
16705088
26.

Identification of strong interleukin-10 inducing lactic acid bacteria which down-regulate T helper type 2 cytokines.

Niers LE, Timmerman HM, Rijkers GT, van Bleek GM, van Uden NO, Knol EF, Kapsenberg ML, Kimpen JL, Hoekstra MO.

Clin Exp Allergy. 2005 Nov;35(11):1481-9.

PMID:
16297146
27.
28.

Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin.

Smits HH, Engering A, van der Kleij D, de Jong EC, Schipper K, van Capel TM, Zaat BA, Yazdanbakhsh M, Wierenga EA, van Kooyk Y, Kapsenberg ML.

J Allergy Clin Immunol. 2005 Jun;115(6):1260-7.

PMID:
15940144
29.

Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity.

Bennett CL, van Rijn E, Jung S, Inaba K, Steinman RM, Kapsenberg ML, Clausen BE.

J Cell Biol. 2005 May 23;169(4):569-76. Epub 2005 May 16.

30.

Different faces of regulatory DCs in homeostasis and immunity.

Smits HH, de Jong EC, Wierenga EA, Kapsenberg ML.

Trends Immunol. 2005 Mar;26(3):123-9. Review. No abstract available.

PMID:
15745853
31.

Dendritic cell-mediated T cell polarization.

de Jong EC, Smits HH, Kapsenberg ML.

Springer Semin Immunopathol. 2005 Jan;26(3):289-307. Epub 2004 Oct 14. Review.

PMID:
15609003
32.

Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN.

Bergman MP, Engering A, Smits HH, van Vliet SJ, van Bodegraven AA, Wirth HP, Kapsenberg ML, Vandenbroucke-Grauls CM, van Kooyk Y, Appelmelk BJ.

J Exp Med. 2004 Oct 18;200(8):979-90.

33.

alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity.

Mailliard RB, Wankowicz-Kalinska A, Cai Q, Wesa A, Hilkens CM, Kapsenberg ML, Kirkwood JM, Storkus WJ, Kalinski P.

Cancer Res. 2004 Sep 1;64(17):5934-7.

34.

ICOS expression by activated human Th cells is enhanced by IL-12 and IL-23: increased ICOS expression enhances the effector function of both Th1 and Th2 cells.

Wassink L, Vieira PL, Smits HH, Kingsbury GA, Coyle AJ, Kapsenberg ML, Wierenga EA.

J Immunol. 2004 Aug 1;173(3):1779-86.

35.

Allergen immunotherapy induces a suppressive memory response mediated by IL-10 in a mouse asthma model.

Vissers JL, van Esch BC, Hofman GA, Kapsenberg ML, Weller FR, van Oosterhout AJ.

J Allergy Clin Immunol. 2004 Jun;113(6):1204-10.

PMID:
15208606
36.

Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development.

Smits HH, van Beelen AJ, Hessle C, Westland R, de Jong E, Soeteman E, Wold A, Wierenga EA, Kapsenberg ML.

Eur J Immunol. 2004 May;34(5):1371-80.

37.

ICOS-mediated signaling regulates cytokine production by human T cells and provides a unique signal to selectively control the clonal expansion of Th2 helper cells.

Vieira PL, Wassink L, Smith LM, Nam S, Kingsbury GA, Gutierrez-Ramos JC, Coyle AJ, Kapsenberg ML, Wierenga EA.

Eur J Immunol. 2004 May;34(5):1282-90.

38.

Dichotomy between Lactobacillus rhamnosus and Klebsiella pneumoniae on dendritic cell phenotype and function.

Braat H, de Jong EC, van den Brande JM, Kapsenberg ML, Peppelenbosch MP, van Tol EA, van Deventer SJ.

J Mol Med (Berl). 2004 Mar;82(3):197-205. Epub 2003 Dec 13.

PMID:
14673529
39.

Dendritic-cell control of pathogen-driven T-cell polarization.

Kapsenberg ML.

Nat Rev Immunol. 2003 Dec;3(12):984-93. Review. No abstract available.

PMID:
14647480
40.

Analysis of the CD4+ T cell responses to house dust mite allergoid.

Kalinski P, Lebre MC, Kramer D, De Jong EC, Van Schijndel JW, Kapsenberg ML.

Allergy. 2003 Jul;58(7):648-56.

PMID:
12823126
41.
43.

Glatiramer acetate (copolymer-1, copaxone) promotes Th2 cell development and increased IL-10 production through modulation of dendritic cells.

Vieira PL, Heystek HC, Wormmeester J, Wierenga EA, Kapsenberg ML.

J Immunol. 2003 May 1;170(9):4483-8.

44.

A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization.

van der Kleij D, Latz E, Brouwers JF, Kruize YC, Schmitz M, Kurt-Jones EA, Espevik T, de Jong EC, Kapsenberg ML, Golenbock DT, Tielens AG, Yazdanbakhsh M.

J Biol Chem. 2002 Dec 13;277(50):48122-9. Epub 2002 Sep 30.

45.

Differential transmission of human immunodeficiency virus type 1 by distinct subsets of effector dendritic cells.

Sanders RW, de Jong EC, Baldwin CE, Schuitemaker JH, Kapsenberg ML, Berkhout B.

J Virol. 2002 Aug;76(15):7812-21.

46.

Triggering of innate immune responses by schistosome egg glycolipids and their carbohydrate epitope GalNAc beta 1-4(Fuc alpha 1-2Fuc alpha 1-3)GlcNAc.

Van der Kleij D, Van Remoortere A, Schuitemaker JH, Kapsenberg ML, Deelder AM, Tielens AG, Hokke CH, Yazdanbakhsh M.

J Infect Dis. 2002 Feb 15;185(4):531-9. Epub 2002 Jan 18.

PMID:
11865406
47.

Complementary dendritic cell-activating function of CD8+ and CD4+ T cells: helper role of CD8+ T cells in the development of T helper type 1 responses.

Mailliard RB, Egawa S, Cai Q, Kalinska A, Bykovskaya SN, Lotze MT, Kapsenberg ML, Storkus WJ, Kalinski P.

J Exp Med. 2002 Feb 18;195(4):473-83.

48.

Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development.

Smits HH, de Jong EC, Schuitemaker JH, Geijtenbeek TB, van Kooyk Y, Kapsenberg ML, Wierenga EA.

J Immunol. 2002 Feb 15;168(4):1710-6.

49.

Microbial compounds selectively induce Th1 cell-promoting or Th2 cell-promoting dendritic cells in vitro with diverse th cell-polarizing signals.

de Jong EC, Vieira PL, Kalinski P, Schuitemaker JH, Tanaka Y, Wierenga EA, Yazdanbakhsh M, Kapsenberg ML.

J Immunol. 2002 Feb 15;168(4):1704-9.

50.

How to deal with polarized Th2 cells: exploring the Achilles' heel.

Smits HH, Hilkens CM, Kalinski P, Kapsenberg ML, Wierenga EA.

Int Arch Allergy Immunol. 2001 Oct;126(2):102-10. Review.

PMID:
11729347

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