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Items: 1 to 50 of 510

1.

Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules.

Krovi SH, Kappler JW, Marrack P, Gapin L.

Proc Natl Acad Sci U S A. 2019 Sep 30. pii: 201909504. doi: 10.1073/pnas.1909504116. [Epub ahead of print]

2.

Structural characteristics of lipocalin allergens: Crystal structure of the immunogenic dog allergen Can f 6.

Clayton GM, White J, Lee S, Kappler JW, Chan SK.

PLoS One. 2019 Sep 16;14(9):e0213052. doi: 10.1371/journal.pone.0213052. eCollection 2019.

3.

Memory-kernel extraction for different molecular solutes in solvents of varying viscosity in confinement.

Kowalik B, Daldrop JO, Kappler J, Schulz JCF, Schlaich A, Netz RR.

Phys Rev E. 2019 Jul;100(1-1):012126. doi: 10.1103/PhysRevE.100.012126.

PMID:
31499907
4.

Non-Markovian barrier crossing with two-time-scale memory is dominated by the faster memory component.

Kappler J, Hinrichsen VB, Netz RR.

Eur Phys J E Soft Matter. 2019 Sep 10;42(9):119. doi: 10.1140/epje/i2019-11886-7.

PMID:
31494784
5.

How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.

Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S.

Sci Immunol. 2019 Apr 5;4(34). pii: eaav7517. doi: 10.1126/sciimmunol.aav7517.

PMID:
30952805
6.

Diagnostic accuracy of physician-staffed emergency medical teams: a retrospective observational cohort study of prehospital versus hospital diagnosis in a 10-year interval.

Schewe JC, Kappler J, Dovermann K, Graeff I, Ehrentraut SF, Heister U, Hoeft A, Weber SU, Muenster S.

Scand J Trauma Resusc Emerg Med. 2019 Apr 2;27(1):36. doi: 10.1186/s13049-019-0617-3.

7.

Cyclization and Relaxation Dynamics of Finite-Length Collapsed Self-Avoiding Polymers.

Kappler J, Noé F, Netz RR.

Phys Rev Lett. 2019 Feb 15;122(6):067801. doi: 10.1103/PhysRevLett.122.067801.

PMID:
30822085
8.

Collective hydrogen-bond rearrangement dynamics in liquid water.

Schulz R, von Hansen Y, Daldrop JO, Kappler J, Noé F, Netz RR.

J Chem Phys. 2018 Dec 28;149(24):244504. doi: 10.1063/1.5054267.

PMID:
30599706
9.

Atomic Scale Evidence of the Switching Mechanism in a Photomagnetic CoFe Dinuclear Prussian Blue Analogue.

Jafri SF, Koumousi ES, Arrio MA, Juhin A, Mitcov D, Rouzières M, Dechambenoit P, Li D, Otero E, Wilhelm F, Rogalev A, Joly L, Kappler JP, Cartier Dit Moulin C, Mathonière C, Clérac R, Sainctavit P.

J Am Chem Soc. 2019 Feb 27;141(8):3470-3479. doi: 10.1021/jacs.8b10484. Epub 2018 Dec 17.

PMID:
30501181
10.

Ultralow-temperature device dedicated to soft X-ray magnetic circular dichroism experiments.

Kappler JP, Otero E, Li W, Joly L, Schmerber G, Muller B, Scheurer F, Leduc F, Gobaut B, Poggini L, Serrano G, Choueikani F, Lhotel E, Cornia A, Sessoli R, Mannini M, Arrio MA, Sainctavit P, Ohresser P.

J Synchrotron Radiat. 2018 Nov 1;25(Pt 6):1727-1735. doi: 10.1107/S1600577518012717. Epub 2018 Oct 19.

11.

Development of T cell lines sensitive to antigen stimulation.

Williams T, Krovi HS, Landry LG, Crawford F, Jin N, Hohenstein A, DeNicola ME, Michels AW, Davidson HW, Kent SC, Gapin L, Kappler JW, Nakayama M.

J Immunol Methods. 2018 Nov;462:65-73. doi: 10.1016/j.jim.2018.08.011. Epub 2018 Aug 28.

PMID:
30165064
12.

Butane dihedral angle dynamics in water is dominated by internal friction.

Daldrop JO, Kappler J, Brünig FN, Netz RR.

Proc Natl Acad Sci U S A. 2018 May 15;115(20):5169-5174. doi: 10.1073/pnas.1722327115. Epub 2018 Apr 30.

13.

Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.

Liu H, Wang C, Lee S, Ning F, Wang Y, Zhang Q, Chen Z, Zang J, Nix J, Dai S, Marrack P, Hagman J, Kappler J, Zhang G.

Sci Rep. 2018 Feb 19;8(1):3275. doi: 10.1038/s41598-018-21432-8.

14.

MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection.

Rozanov DV, Rozanov ND, Chiotti KE, Reddy A, Wilmarth PA, David LL, Cha SW, Woo S, Pevzner P, Bafna V, Burrows GG, Rantala JK, Levin T, Anur P, Johnson-Camacho K, Tabatabaei S, Munson DJ, Bruno TC, Slansky JE, Kappler JW, Hirano N, Boegel S, Fox BA, Egelston C, Simons DL, Jimenez G, Lee PP, Gray JW, Spellman PT.

J Proteomics. 2018 Mar 30;176:13-23. doi: 10.1016/j.jprot.2018.01.004. Epub 2018 Jan 10.

15.

Memory-induced acceleration and slowdown of barrier crossing.

Kappler J, Daldrop JO, Brünig FN, Boehle MD, Netz RR.

J Chem Phys. 2018 Jan 7;148(1):014903. doi: 10.1063/1.4998239.

PMID:
29306292
16.

C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.

Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S.

Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):162-167. doi: 10.1073/pnas.1716527115. Epub 2017 Dec 18.

17.

Synthesis, spectroscopic characterisation and transmetalation of lithium and potassium diaminophosphanide-boranes.

Blum M, Kappler J, Schlindwein SH, Nieger M, Gudat D.

Dalton Trans. 2017 Dec 19;47(1):112-119. doi: 10.1039/c7dt04110a.

PMID:
29188837
18.

The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor.

Marrack P, Krovi SH, Silberman D, White J, Kushnir E, Nakayama M, Crooks J, Danhorn T, Leach S, Anselment R, Scott-Browne J, Gapin L, Kappler J.

Elife. 2017 Nov 17;6. pii: e30918. doi: 10.7554/eLife.30918.

19.

Hydration Friction in Nanoconfinement: From Bulk via Interfacial to Dry Friction.

Schlaich A, Kappler J, Netz RR.

Nano Lett. 2017 Oct 11;17(10):5969-5976. doi: 10.1021/acs.nanolett.7b02000. Epub 2017 Sep 21.

PMID:
28910108
20.

Clipping of arginine-methylated histone tails by JMJD5 and JMJD7.

Liu H, Wang C, Lee S, Deng Y, Wither M, Oh S, Ning F, Dege C, Zhang Q, Liu X, Johnson AM, Zang J, Chen Z, Janknecht R, Hansen K, Marrack P, Li CY, Kappler JW, Hagman J, Zhang G.

Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):E7717-E7726. doi: 10.1073/pnas.1706831114. Epub 2017 Aug 28.

21.

The domestic cat antibody response to feline herpesvirus-1 increases with age.

Munks MW, Montoya AM, Pywell CM, Talmage G, Forssen A, Campbell TL, Dodge DD, Kappler JW, Marrack P.

Vet Immunol Immunopathol. 2017 Jun;188:65-70. doi: 10.1016/j.vetimm.2017.05.002. Epub 2017 May 4.

PMID:
28615129
22.

B cells expressing the transcription factor T-bet drive lupus-like autoimmunity.

Rubtsova K, Rubtsov AV, Thurman JM, Mennona JM, Kappler JW, Marrack P.

J Clin Invest. 2017 Apr 3;127(4):1392-1404. doi: 10.1172/JCI91250. Epub 2017 Feb 27.

23.

Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes.

Michels AW, Landry LG, McDaniel KA, Yu L, Campbell-Thompson M, Kwok WW, Jones KL, Gottlieb PA, Kappler JW, Tang Q, Roep BO, Atkinson MA, Mathews CE, Nakayama M.

Diabetes. 2017 Mar;66(3):722-734. doi: 10.2337/db16-1025. Epub 2016 Dec 5.

24.

T Cell Production of IFNγ in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses.

Rubtsova K, Rubtsov AV, Halemano K, Li SX, Kappler JW, Santiago ML, Marrack P.

PLoS One. 2016 Nov 23;11(11):e0166322. doi: 10.1371/journal.pone.0166322. eCollection 2016.

25.

Pillars Article: Characterization of a Monoclonal Antibody Which Detects All Murine αβ T Cell Receptors. J. Immunol. 1989. 142: 2736-2742.

Kubo RT, Born W, Kappler JW, Marrack P, Pigeon M.

J Immunol. 2016 Nov 1;197(9):3437-3443. No abstract available.

26.

Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion.

Ranasinghe S, Lamothe PA, Soghoian DZ, Kazer SW, Cole MB, Shalek AK, Yosef N, Jones RB, Donaghey F, Nwonu C, Jani P, Clayton GM, Crawford F, White J, Montoya A, Power K, Allen TM, Streeck H, Kaufmann DE, Picker LJ, Kappler JW, Walker BD.

Immunity. 2016 Oct 18;45(4):917-930. doi: 10.1016/j.immuni.2016.09.015.

27.

Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors.

Silberman D, Krovi SH, Tuttle KD, Crooks J, Reisdorph R, White J, Gross J, Matsuda JL, Gapin L, Marrack P, Kappler JW.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5608-17. doi: 10.1073/pnas.1609717113. Epub 2016 Sep 1.

28.

Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines.

Noges LE, White J, Cambier JC, Kappler JW, Marrack P.

J Immunol. 2016 Aug 15;197(4):1221-30. doi: 10.4049/jimmunol.1501565. Epub 2016 Jun 29.

29.

Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR.

Munson DJ, Egelston CA, Chiotti KE, Parra ZE, Bruno TC, Moore BL, Nakano TA, Simons DL, Jimenez G, Yim JH, Rozanov DV, Falta MT, Fontenot AP, Reynolds PR, Leach SM, Borges VF, Kappler JW, Spellman PT, Lee PP, Slansky JE.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8272-7. doi: 10.1073/pnas.1606994113. Epub 2016 Jun 15.

30.

Versatile variable temperature insert at the DEIMOS beamline for in situ electrical transport measurements.

Joly L, Muller B, Sternitzky E, Faullumel JG, Boulard A, Otero E, Choueikani F, Kappler JP, Studniarek M, Bowen M, Ohresser P.

J Synchrotron Radiat. 2016 May;23(Pt 3):652-7. doi: 10.1107/S1600577516002551. Epub 2016 Apr 2.

PMID:
27140143
31.

Beryllium-Induced Hypersensitivity: Genetic Susceptibility and Neoantigen Generation.

Fontenot AP, Falta MT, Kappler JW, Dai S, McKee AS.

J Immunol. 2016 Jan 1;196(1):22-7. doi: 10.4049/jimmunol.1502011. Review.

32.

Anti-inflammatory activity of low molecular weight polysialic acid on human macrophages.

Shahraz A, Kopatz J, Mathy R, Kappler J, Winter D, Kapoor S, Schütza V, Scheper T, Gieselmann V, Neumann H.

Sci Rep. 2015 Nov 19;5:16800. doi: 10.1038/srep16800.

33.

N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes.

Jin N, Wang Y, Crawford F, White J, Marrack P, Dai S, Kappler JW.

Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13318-23. doi: 10.1073/pnas.1517862112. Epub 2015 Oct 9.

34.

A Rapid Method to Characterize Mouse IgG Antibodies and Isolate Native Antigen Binding IgG B Cell Hybridomas.

Liu H, White J, Crawford F, Jin N, Ju X, Liu K, Jiang C, Marrack P, Zhang G, Kappler JW.

PLoS One. 2015 Aug 28;10(8):e0136613. doi: 10.1371/journal.pone.0136613. eCollection 2015.

35.

Outcome of out-of-hospital cardiac arrest over a period of 15 years in comparison to the RACA score in a physician staffed urban emergency medical service in Germany.

Schewe JC, Kappler J, Heister U, Weber SU, Diepenseifen CJ, Frings B, Hoeft A, Fischer M.

Resuscitation. 2015 Nov;96:232-8. doi: 10.1016/j.resuscitation.2015.07.025. Epub 2015 Aug 22.

PMID:
26303572
36.

Metal-specific CD4+ T-cell responses induced by beryllium exposure in HLA-DP2 transgenic mice.

Falta MT, Tinega AN, Mack DG, Bowerman NA, Crawford F, Kappler JW, Pinilla C, Fontenot AP.

Mucosal Immunol. 2016 Jan;9(1):218-28. doi: 10.1038/mi.2015.54. Epub 2015 Jul 1.

37.

CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs.

Rubtsov AV, Rubtsova K, Kappler JW, Jacobelli J, Friedman RS, Marrack P.

J Immunol. 2015 Jul 1;195(1):71-9. doi: 10.4049/jimmunol.1500055. Epub 2015 Jun 1.

38.

Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects.

Nakayama M, McDaniel K, Fitzgerald-Miller L, Kiekhaefer C, Snell-Bergeon JK, Davidson HW, Rewers M, Yu L, Gottlieb P, Kappler JW, Michels A.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4429-34. doi: 10.1073/pnas.1502967112. Epub 2015 Mar 23.

39.

Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease.

Ito Y, Hashimoto M, Hirota K, Ohkura N, Morikawa H, Nishikawa H, Tanaka A, Furu M, Ito H, Fujii T, Nomura T, Yamazaki S, Morita A, Vignali DA, Kappler JW, Matsuda S, Mimori T, Sakaguchi N, Sakaguchi S.

Science. 2014 Oct 17;346(6207):363-8. doi: 10.1126/science.1259077.

40.

Monitoring of cerebral oxygen saturation during resuscitation in out-of-hospital cardiac arrest: a feasibility study in a physician staffed emergency medical system.

Schewe JC, Thudium MO, Kappler J, Steinhagen F, Eichhorn L, Erdfelder F, Heister U, Ellerkmann R.

Scand J Trauma Resusc Emerg Med. 2014 Oct 5;22:58. doi: 10.1186/s13049-014-0058-y.

41.

Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes.

Yang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14840-5. doi: 10.1073/pnas.1416864111. Epub 2014 Sep 29.

42.

Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.

Clayton GM, Wang Y, Crawford F, Novikov A, Wimberly BT, Kieft JS, Falta MT, Bowerman NA, Marrack P, Fontenot AP, Dai S, Kappler JW.

Cell. 2014 Jul 3;158(1):132-42. doi: 10.1016/j.cell.2014.04.048.

43.

Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease.

Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8553-8. doi: 10.1073/pnas.1408048111. Epub 2014 May 27.

44.

Hysteretic behaviour in a vacuum deposited submonolayer of single ion magnets.

Klar D, Candini A, Joly L, Klyatskaya S, Krumme B, Ohresser P, Kappler JP, Ruben M, Wende H.

Dalton Trans. 2014 Jul 28;43(28):10686-9. doi: 10.1039/c4dt01005a.

PMID:
24875369
45.

Molecules in medicine mini review: the αβ T cell receptor.

Clambey ET, Davenport B, Kappler JW, Marrack P, Homann D.

J Mol Med (Berl). 2014 Jul;92(7):735-41. doi: 10.1007/s00109-014-1145-2. Epub 2014 May 22. Review.

46.

Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation.

David A, Crawford F, Garside P, Kappler JW, Marrack P, MacLeod M.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7735-40. doi: 10.1073/pnas.1406218111. Epub 2014 May 12.

47.

Identification of multiple public TCR repertoires in chronic beryllium disease.

Bowerman NA, Falta MT, Mack DG, Wehrmann F, Crawford F, Mroz MM, Maier LA, Kappler JW, Fontenot AP.

J Immunol. 2014 May 15;192(10):4571-80. doi: 10.4049/jimmunol.1400007. Epub 2014 Apr 9.

48.

Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes.

Zhang L, Crawford F, Yu L, Michels A, Nakayama M, Davidson HW, Kappler JW, Eisenbarth GS.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2656-61. doi: 10.1073/pnas.1323436111. Epub 2014 Feb 3.

49.

DEIMOS: a beamline dedicated to dichroism measurements in the 350-2500 eV energy range.

Ohresser P, Otero E, Choueikani F, Chen K, Stanescu S, Deschamps F, Moreno T, Polack F, Lagarde B, Daguerre JP, Marteau F, Scheurer F, Joly L, Kappler JP, Muller B, Bunau O, Sainctavit P.

Rev Sci Instrum. 2014 Jan;85(1):013106. doi: 10.1063/1.4861191.

PMID:
24517744
50.

Altered MCM protein levels and autophagic flux in aged and systemic sclerosis dermal fibroblasts.

Dumit VI, Küttner V, Käppler J, Piera-Velazquez S, Jimenez SA, Bruckner-Tuderman L, Uitto J, Dengjel J.

J Invest Dermatol. 2014 Sep;134(9):2321-2330. doi: 10.1038/jid.2014.69. Epub 2014 Feb 4.

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