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Items: 47

1.

CaMKII does not control mitochondrial Ca2+ uptake in cardiac myocytes.

Nickel AG, Kohlhaas M, Bertero E, Wilhelm D, Wagner M, Sequeira V, Kreusser MM, Dewenter M, Kappl R, Hoth M, Dudek J, Backs J, Maack C.

J Physiol. 2019 Feb 16. doi: 10.1113/JP276766. [Epub ahead of print]

2.

Electrochemical Quantification of Extracellular Local H2O2 Kinetics Originating from Single Cells.

Bozem M, Knapp P, Mirčeski V, Slowik EJ, Bogeski I, Kappl R, Heinemann C, Hoth M.

Antioxid Redox Signal. 2018 Aug 20;29(6):501-517. doi: 10.1089/ars.2016.6840. Epub 2017 May 15.

3.

Low STAT3 expression sensitizes to toxic effects of β-adrenergic receptor stimulation in peripartum cardiomyopathy.

Stapel B, Kohlhaas M, Ricke-Hoch M, Haghikia A, Erschow S, Knuuti J, Silvola JM, Roivainen A, Saraste A, Nickel AG, Saar JA, Sieve I, Pietzsch S, Müller M, Bogeski I, Kappl R, Jauhiainen M, Thackeray JT, Scherr M, Bengel FM, Hagl C, Tudorache I, Bauersachs J, Maack C, Hilfiker-Kleiner D.

Eur Heart J. 2017 Feb 1;38(5):349-361. doi: 10.1093/eurheartj/ehw086.

4.

New insights into the chemistry of Coenzyme Q-0: A voltammetric and spectroscopic study.

Gulaboski R, Bogeski I, Kokoskarova P, Haeri HH, Mitrev S, Stefova M, Stanoeva JP, Markovski V, Mirčeski V, Hoth M, Kappl R.

Bioelectrochemistry. 2016 Oct;111:100-8. doi: 10.1016/j.bioelechem.2016.05.008. Epub 2016 May 29.

PMID:
27268099
5.

A calcium-redox feedback loop controls human monocyte immune responses: The role of ORAI Ca2+ channels.

Saul S, Gibhardt CS, Schmidt B, Lis A, Pasieka B, Conrad D, Jung P, Gaupp R, Wonnenberg B, Diler E, Stanisz H, Vogt T, Schwarz EC, Bischoff M, Herrmann M, Tschernig T, Kappl R, Rieger H, Niemeyer BA, Bogeski I.

Sci Signal. 2016 Mar 8;9(418):ra26. doi: 10.1126/scisignal.aaf1639.

PMID:
26956485
6.

Reversal of Mitochondrial Transhydrogenase Causes Oxidative Stress in Heart Failure.

Nickel AG, von Hardenberg A, Hohl M, Löffler JR, Kohlhaas M, Becker J, Reil JC, Kazakov A, Bonnekoh J, Stadelmaier M, Puhl SL, Wagner M, Bogeski I, Cortassa S, Kappl R, Pasieka B, Lafontaine M, Lancaster CR, Blacker TS, Hall AR, Duchen MR, Kästner L, Lipp P, Zeller T, Müller C, Knopp A, Laufs U, Böhm M, Hoth M, Maack C.

Cell Metab. 2015 Sep 1;22(3):472-84. doi: 10.1016/j.cmet.2015.07.008. Epub 2015 Aug 6.

7.

Recognition of bacterial signal peptides by mammalian formyl peptide receptors: a new mechanism for sensing pathogens.

Bufe B, Schumann T, Kappl R, Bogeski I, Kummerow C, Podgórska M, Smola S, Hoth M, Zufall F.

J Biol Chem. 2015 Mar 20;290(12):7369-87. doi: 10.1074/jbc.M114.626747. Epub 2015 Jan 20.

8.

A natural heme-signature variant of CYP267A1 from Sorangium cellulosum So ce56 executes diverse ω-hydroxylation.

Khatri Y, Hannemann F, Girhard M, Kappl R, Hutter M, Urlacher VB, Bernhardt R.

FEBS J. 2015 Jan;282(1):74-88. doi: 10.1111/febs.13104. Epub 2014 Nov 4.

9.

Inverse regulation of melanoma growth and migration by Orai1/STIM2-dependent calcium entry.

Stanisz H, Saul S, Müller CS, Kappl R, Niemeyer BA, Vogt T, Hoth M, Roesch A, Bogeski I.

Pigment Cell Melanoma Res. 2014 May;27(3):442-53. doi: 10.1111/pcmr.12222. Epub 2014 Mar 7.

PMID:
24472175
10.

Substrate-assisted O2 activation in a cofactor-independent dioxygenase.

Thierbach S, Bui N, Zapp J, Chhabra SR, Kappl R, Fetzner S.

Chem Biol. 2014 Feb 20;21(2):217-25. doi: 10.1016/j.chembiol.2013.11.013. Epub 2014 Jan 2.

11.

Heme impairs the ball-and-chain inactivation of potassium channels.

Sahoo N, Goradia N, Ohlenschläger O, Schönherr R, Friedrich M, Plass W, Kappl R, Hoshi T, Heinemann SH.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):E4036-44. doi: 10.1073/pnas.1313247110. Epub 2013 Sep 30.

12.

Hydroxylated derivatives of dimethoxy-1,4-benzoquinone as redox switchable earth-alkaline metal ligands and radical scavengers.

Gulaboski R, Bogeski I, Mirčeski V, Saul S, Pasieka B, Haeri HH, Stefova M, Stanoeva JP, Mitrev S, Hoth M, Kappl R.

Sci Rep. 2013;3:1865. doi: 10.1038/srep01865.

13.

Novel family members of CYP109 from Sorangium cellulosum So ce56 exhibit characteristic biochemical and biophysical properties.

Khatri Y, Hannemann F, Girhard M, Kappl R, Même A, Ringle M, Janocha S, Leize-Wagner E, Urlacher VB, Bernhardt R.

Biotechnol Appl Biochem. 2013 Jan-Feb;60(1):18-29. doi: 10.1002/bab.1087.

PMID:
23586989
14.

Redox regulation of calcium ion channels: chemical and physiological aspects.

Bogeski I, Kappl R, Kummerow C, Gulaboski R, Hoth M, Niemeyer BA.

Cell Calcium. 2011 Nov;50(5):407-23. doi: 10.1016/j.ceca.2011.07.006. Epub 2011 Sep 17. Review.

PMID:
21930299
15.

Heart-rate reduction by If-channel inhibition with ivabradine restores collateral artery growth in hypercholesterolemic atherosclerosis.

Schirmer SH, Degen A, Baumhäkel M, Custodis F, Schuh L, Kohlhaas M, Friedrich E, Bahlmann F, Kappl R, Maack C, Böhm M, Laufs U.

Eur Heart J. 2012 May;33(10):1223-31. doi: 10.1093/eurheartj/ehr255. Epub 2011 Aug 6.

PMID:
21821843
16.

Determination of copper(II) ion concentration by lifetime measurements of green fluorescent protein.

Hötzer B, Ivanov R, Altmeier S, Kappl R, Jung G.

J Fluoresc. 2011 Nov;21(6):2143-53. doi: 10.1007/s10895-011-0916-1. Epub 2011 Jul 20.

PMID:
21773693
17.

ISC-like [2Fe-2S] ferredoxin (FdxB) dimer from Pseudomonas putida JCM 20004: structural and electron-nuclear double resonance characterization.

Iwasaki T, Kappl R, Bracic G, Shimizu N, Ohmori D, Kumasaka T.

J Biol Inorg Chem. 2011 Aug;16(6):923-35. doi: 10.1007/s00775-011-0793-8. Epub 2011 Jun 7.

PMID:
21647778
18.

Calcium binding and transport by coenzyme Q.

Bogeski I, Gulaboski R, Kappl R, Mirceski V, Stefova M, Petreska J, Hoth M.

J Am Chem Soc. 2011 Jun 22;133(24):9293-303. doi: 10.1021/ja110190t. Epub 2011 May 24.

PMID:
21548646
19.

Structural and thermodynamic characterization of the adrenodoxin-like domain of the electron-transfer protein Etp1 from Schizosaccharomyces pombe.

Müller JJ, Hannemann F, Schiffler B, Ewen KM, Kappl R, Heinemann U, Bernhardt R.

J Inorg Biochem. 2011 Jul;105(7):957-65. doi: 10.1016/j.jinorgbio.2011.04.001. Epub 2011 Apr 9.

PMID:
21536008
20.

Genome mining in Sorangium cellulosum So ce56: identification and characterization of the homologous electron transfer proteins of a myxobacterial cytochrome P450.

Ewen KM, Hannemann F, Khatri Y, Perlova O, Kappl R, Krug D, Hüttermann J, Müller R, Bernhardt R.

J Biol Chem. 2009 Oct 16;284(42):28590-8. doi: 10.1074/jbc.M109.021717. Epub 2009 Aug 20.

21.

The reduced [2Fe-2S] clusters in adrenodoxin and Arthrospira platensis ferredoxin share spin density with protein nitrogens, probed using 2D ESEEM.

Dikanov SA, Samoilova RI, Kappl R, Crofts AR, Hüttermann J.

Phys Chem Chem Phys. 2009 Aug 21;11(31):6807-19. doi: 10.1039/b904597j. Epub 2009 Jul 1.

22.

Large hierarchies from approximate R symmetries.

Kappl R, Nilles HP, Ramos-Sánchez S, Ratz M, Schmidt-Hoberg K, Vaudrevange PK.

Phys Rev Lett. 2009 Mar 27;102(12):121602. Epub 2009 Mar 27.

23.

Quercetinase QueD of Streptomyces sp. FLA, a monocupin dioxygenase with a preference for nickel and cobalt.

Merkens H, Kappl R, Jakob RP, Schmid FX, Fetzner S.

Biochemistry. 2008 Nov 18;47(46):12185-96. doi: 10.1021/bi801398x. Epub 2008 Oct 25.

PMID:
18950192
24.

Mechanism of inhibition of P-glycoprotein mediated efflux by vitamin E TPGS: influence on ATPase activity and membrane fluidity.

Collnot EM, Baldes C, Wempe MF, Kappl R, Hüttermann J, Hyatt JA, Edgar KJ, Schaefer UF, Lehr CM.

Mol Pharm. 2007 May-Jun;4(3):465-74. Epub 2007 Mar 17.

PMID:
17367162
25.

Spectroscopic and biochemical studies on protein variants of quinaldine 4-oxidase: Role of E736 in catalysis and effects of serine ligands on the FeSI and FeSII clusters.

Kappl R, Sielker S, Ranguelova K, Wegner J, Parschat K, Hüttermann J, Fetzner S.

Biochemistry. 2006 Dec 12;45(49):14853-68.

PMID:
17144679
26.

Multi-frequency high-field EPR studies on metal-substituted xylose isomerase.

Kappl R, Ranguelova K, Koch B, Duboc C, Hüttermann J.

Magn Reson Chem. 2005 Nov;43 Spec no.:S65-73.

PMID:
16235215
28.
29.

Functional expression of the quinoline 2-oxidoreductase genes (qorMSL) in Pseudomonas putida KT2440 pUF1 and in P. putida 86-1 deltaqor pUF1 and analysis of the Qor proteins.

Frerichs-Deeken U, Goldenstedt B, Gahl-Janssen R, Kappl R, Hüttermann J, Fetzner S.

Eur J Biochem. 2003 Apr;270(7):1567-77.

30.

The molybdenum-containing hydroxylases of quinoline, isoquinoline, and quinaldine.

Kappl R, Hüttermann J, Fetzner S.

Met Ions Biol Syst. 2002;39:481-537. Review. No abstract available.

PMID:
11913135
31.

Hydrogenases in the "active" state: determination of g-matrix axes and electron spin distribution at the active site by 1H ENDOR spectroscopy.

Müller A, Tscherny I, Kappl R, Hatchikian C, Hüttermann J, Cammack R.

J Biol Inorg Chem. 2002 Jan;7(1-2):177-94. Epub 2001 Sep 21.

PMID:
11862554
32.

Xanthine dehydrogenase from Pseudomonas putida 86: specificity, oxidation-reduction potentials of its redox-active centers, and first EPR characterization.

Parschat K, Canne C, Hüttermann J, Kappl R, Fetzner S.

Biochim Biophys Acta. 2001 Jan 12;1544(1-2):151-65.

PMID:
11341925
33.

Probing magnetic properties of the reduced [2Fe-2S] cluster of the ferredoxin from Arthrospira platensis by 1H ENDOR spectroscopy.

Canne C, Ebelshäuser M, Gay E, Shergill JK, Cammack R, Kappl R, Hüttermann J.

J Biol Inorg Chem. 2000 Aug;5(4):514-26.

PMID:
10968623
34.

Role of the binuclear manganese(II) site in xylose isomerase.

Bogumil R, Kappl R, Hüttermann J.

Met Ions Biol Syst. 2000;37:365-405. Review. No abstract available.

PMID:
10693140
35.

Kinetics and interactions of molybdenum and iron-sulfur centers in bacterial enzymes of the xanthine oxidase family: mechanistic implications.

Canne C, Lowe DJ, Fetzner S, Adams B, Smith AT, Kappl R, Bray RC, Hüttermann J.

Biochemistry. 1999 Oct 19;38(42):14077-87.

PMID:
10529255
36.

Flavonol 2,4-dioxygenase from Aspergillus niger DSM 821, a type 2 CuII-containing glycoprotein.

Hund HK, Breuer J, Lingens F, Hüttermann J, Kappl R, Fetzner S.

Eur J Biochem. 1999 Aug;263(3):871-8.

37.

The active site of purple acid phosphatase from sweet potatoes (Ipomoea batatas) metal content and spectroscopic characterization.

Durmus A, Eicken C, Sift BH, Kratel A, Kappl R, Hüttermann J, Krebs B.

Eur J Biochem. 1999 Mar;260(3):709-16.

38.

A divalent metal site in the small subunit of the manganese-dependent ribonucleotide reductase of Corynebacterium ammoniagenes.

Griepenburg U, Blasczyk K, Kappl R, Hüttermann J, Auling G.

Biochemistry. 1998 Jun 2;37(22):7992-6.

PMID:
9609691
39.
40.

Bacterial Degradation of Quinoline and Derivatives-Pathways and Their Biocatalysts.

Fetzner S, Tshisuaka B, Lingens F, Kappl R, Hüttermann J.

Angew Chem Int Ed Engl. 1998 Mar 16;37(5):576-597. doi: 10.1002/(SICI)1521-3773(19980316)37:5<576::AID-ANIE576>3.0.CO;2-L. Review.

PMID:
29711093
41.

Comparative EPR and redox studies of three prokaryotic enzymes of the xanthine oxidase family: quinoline 2-oxidoreductase, quinaldine 4-oxidase, and isoquinoline 1-oxidoreductase.

Canne C, Stephan I, Finsterbusch J, Lingens F, Kappl R, Fetzner S, Hüttermann J.

Biochemistry. 1997 Aug 12;36(32):9780-90.

PMID:
9245410
42.
43.

Quinoline oxidoreductase from Pseudomonas putida 86: an improved purification procedure and electron paramagnetic resonance spectroscopy.

Tshisuaka B, Kappl R, Hüttermann J, Lingens F.

Biochemistry. 1993 Nov 30;32(47):12928-34.

PMID:
8251516
44.

X- and Q-band EPR studies on the two Mn(2+)-substituted metal-binding sites of D-xylose isomerase.

Bogumil R, Kappl R, Hüttermann J, Sudfeldt C, Witzel H.

Eur J Biochem. 1993 May 1;213(3):1185-92.

45.

EPR-spectroscopy of reduced oxyferrous-P450cam.

Davydov R, Kappl R, Hüttermann J, Peterson JA.

FEBS Lett. 1991 Dec 16;295(1-3):113-5.

46.

Visible, EPR and electron nuclear double-resonance spectroscopic studies on the two metal-binding sites of oxovanadium (IV)-substituted D-xylose isomerase.

Bogumil R, Hüttermann J, Kappl R, Stabler R, Sudfeldt C, Witzel H.

Eur J Biochem. 1991 Mar 14;196(2):305-12.

47.

An ENDOR study of human and bovine erythrocyte superoxide dismutase: 1H and 14N interactions.

Hüttermann J, Kappl R, Banci L, Bertini I.

Biochim Biophys Acta. 1988 Sep 21;956(2):173-88.

PMID:
2844267

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