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Items: 7


A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing.

Kapoor-Vazirani P, Vertino PM.

J Biol Chem. 2014 Mar 14;289(11):7425-37. doi: 10.1074/jbc.M113.520783. Epub 2014 Jan 23.


A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation.

Duncan CG, Barwick BG, Jin G, Rago C, Kapoor-Vazirani P, Powell DR, Chi JT, Bigner DD, Vertino PM, Yan H.

Genome Res. 2012 Dec;22(12):2339-55. doi: 10.1101/gr.132738.111. Epub 2012 Aug 16.


SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation.

Kapoor-Vazirani P, Kagey JD, Vertino PM.

Mol Cell Biol. 2011 Apr;31(8):1594-609. doi: 10.1128/MCB.00524-10. Epub 2011 Feb 14.


Long-term stability of demethylation after transient exposure to 5-aza-2'-deoxycytidine correlates with sustained RNA polymerase II occupancy.

Kagey JD, Kapoor-Vazirani P, McCabe MT, Powell DR, Vertino PM.

Mol Cancer Res. 2010 Jul;8(7):1048-59. doi: 10.1158/1541-7786.MCR-10-0189. Epub 2010 Jun 29.


Methylation-sensitive regulation of TMS1/ASC by the Ets factor, GA-binding protein-alpha.

Lucas ME, Crider KS, Powell DR, Kapoor-Vazirani P, Vertino PM.

J Biol Chem. 2009 May 29;284(22):14698-709. doi: 10.1074/jbc.M901104200. Epub 2009 Mar 25.


Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity.

Kapoor-Vazirani P, Kagey JD, Powell DR, Vertino PM.

Cancer Res. 2008 Aug 15;68(16):6810-21. doi: 10.1158/0008-5472.CAN-08-0141.


Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase.

Subramanian K, Jia D, Kapoor-Vazirani P, Powell DR, Collins RE, Sharma D, Peng J, Cheng X, Vertino PM.

Mol Cell. 2008 May 9;30(3):336-47. doi: 10.1016/j.molcel.2008.03.022.

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