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Items: 1 to 50 of 133


Single-Stage Direct-to-Implant Breast Reconstruction: A Comparison Between Subpectoral Versus Prepectoral Implant Placement.

Manrique OJ, Kapoor T, Banuelos J, Jacobson SR, Martinez-Jorge J, Nguyen MT, Tran NV, Harless CA, Degnim AC, Jakub JW.

Ann Plast Surg. 2019 Oct 14. doi: 10.1097/SAP.0000000000002028. [Epub ahead of print]


Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins.

Pisa R, Cupido T, Steinman JB, Jones NH, Kapoor TM.

Cell Chem Biol. 2019 Sep 19;26(9):1263-1273.e5. doi: 10.1016/j.chembiol.2019.06.001. Epub 2019 Jun 27.


High-resolution imaging reveals how the spindle midzone impacts chromosome movement.

Pamula MC, Carlini L, Forth S, Verma P, Suresh S, Legant WR, Khodjakov A, Betzig E, Kapoor TM.

J Cell Biol. 2019 Aug 5;218(8):2529-2544. doi: 10.1083/jcb.201904169. Epub 2019 Jun 27.


Postoperative Management After Total Pharyngolaryngectomy Using the Free Ileocolon Flap: A 5-Year Surgical Intensive Care Unit Experience.

Manrique OJ, Sabbagh MD, Kapoor T, Ciudad P, Chen HC.

Ann Plast Surg. 2019 Jun 25. doi: 10.1097/SAP.0000000000001953. [Epub ahead of print]


Association between hydroxychloroquine levels and disease activity in a predominantly Hispanic systemic lupus erythematosus cohort.

Geraldino-Pardilla L, Perel-Winkler A, Miceli J, Neville K, Danias G, Nguyen S, Dervieux T, Kapoor T, Giles J, Askanase A.

Lupus. 2019 Jun;28(7):862-867. doi: 10.1177/0961203319851558. Epub 2019 May 24.


Using chemical inhibitors to probe AAA protein conformational dynamics and cellular functions.

Steinman JB, Kapoor TM.

Curr Opin Chem Biol. 2019 Jun;50:45-54. doi: 10.1016/j.cbpa.2019.02.019. Epub 2019 Mar 23. Review.


Designing Allele-Specific Inhibitors of Spastin, a Microtubule-Severing AAA Protein.

Pisa R, Cupido T, Kapoor TM.

J Am Chem Soc. 2019 Apr 10;141(14):5602-5606. doi: 10.1021/jacs.8b13257. Epub 2019 Mar 27.


Return of baseline kidney function after bilateral renal artery stent occlusion and treatment delay following fenestrated endografting.

Kapoor T, Oderich GS, DeMartino RR.

J Vasc Surg. 2019 Jul;70(1):262-266. doi: 10.1016/j.jvs.2018.12.020. Epub 2019 Mar 8.


Designing a chemical inhibitor for the AAA protein spastin using active site mutations.

Cupido T, Pisa R, Kelley ME, Kapoor TM.

Nat Chem Biol. 2019 May;15(5):444-452. doi: 10.1038/s41589-019-0225-6. Epub 2019 Feb 18.


Cost Analysis and Supply Utilization of Laparoscopic Cholecystectomy.

Kapoor T, Wrenn SM, Callas PW, Abu-Jaish W.

Minim Invasive Surg. 2018 Dec 10;2018:7838103. doi: 10.1155/2018/7838103. eCollection 2018.


Atypical septate junctions maintain the somatic enclosure around maturing spermatids and prevent premature sperm release in Drosophila testis.

Dubey P, Kapoor T, Gupta S, Shirolikar S, Ray K.

Biol Open. 2019 Feb 4;8(2). pii: bio036939. doi: 10.1242/bio.036939.


Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis.

Chen Z, Suzuki H, Kobayashi Y, Wang AC, DiMaio F, Kawashima SA, Walz T, Kapoor TM.

Cell. 2018 Oct 18;175(3):822-834.e18. doi: 10.1016/j.cell.2018.09.015. Epub 2018 Oct 11.


Renal Manifestations of Rheumatoid Arthritis.

Kapoor T, Bathon J.

Rheum Dis Clin North Am. 2018 Nov;44(4):571-584. doi: 10.1016/j.rdc.2018.06.008. Epub 2018 Sep 7. Review.


Human β-Tubulin Isotypes Can Regulate Microtubule Protofilament Number and Stability.

Ti SC, Alushin GM, Kapoor TM.

Dev Cell. 2018 Oct 22;47(2):175-190.e5. doi: 10.1016/j.devcel.2018.08.014. Epub 2018 Sep 20.


Analysis of clinical outcomes of upper and lower extremity reconstructions in patients with soft-tissue sarcoma.

Kapoor T, Banuelos J, Adabi K, Moran SL, Manrique OJ.

J Surg Oncol. 2018 Sep;118(4):614-620. doi: 10.1002/jso.25201. Epub 2018 Sep 9.


Damage accrual in systemic lupus erythematosus in Dominicans in New York City and the Dominican Republic.

Geraldino-Pardilla L, Kapoor T, Canto I, Perez-Recio T, Then J, Tineo C, Loyo E, Askanase A.

Lupus. 2018 Oct;27(12):1989-1995. doi: 10.1177/0961203318791764. Epub 2018 Aug 9.


Analyzing the micromechanics of the cell division apparatus.

Shimamoto Y, Kapoor TM.

Methods Cell Biol. 2018;145:173-190. doi: 10.1016/bs.mcb.2018.03.022. Epub 2018 May 1.


A Stepwise Approach to Laparoscopic Enucleation and Excision of Retroperitoneal Cysts.

Jan H, Kapoor T, Ghai V.

J Minim Invasive Gynecol. 2019 Feb;26(2):367-368. doi: 10.1016/j.jmig.2018.05.009. Epub 2018 May 18.


A Chemical Proteomics Approach to Reveal Direct Protein-Protein Interactions in Living Cells.

Kleiner RE, Hang LE, Molloy KR, Chait BT, Kapoor TM.

Cell Chem Biol. 2018 Jan 18;25(1):110-120.e3. doi: 10.1016/j.chembiol.2017.10.001. Epub 2017 Nov 5.


Leveraging Chemotype-Specific Resistance for Drug Target Identification and Chemical Biology.

Kapoor TM, Miller RM.

Trends Pharmacol Sci. 2017 Dec;38(12):1100-1109. doi: 10.1016/ Epub 2017 Oct 13. Review.


Comparison of the Lupus Foundation of America-Rapid Evaluation of Activity in Lupus to More Complex Disease Activity Instruments As Evaluated by Clinical Investigators or Real-World Clinicians.

Askanase AD, Nguyen SC, Costenbader K, Lim SS, Kamen D, Aranow C, Grossman J, Kapoor TM, Baker-Frost D, Aberle T, Thanou-Stavraki A, Hanrahan LM, Kim M, Merrill JT.

Arthritis Care Res (Hoboken). 2018 Jul;70(7):1058-1063. doi: 10.1002/acr.23445. Epub 2018 May 21.


Increased risk organ transplantation in the pediatric population.

Wrenn SM, Callas PW, Kapoor T, Aunchman AF, Paine AN, Pineda JA, Marroquin CE.

Pediatr Transplant. 2017 Dec;21(8). doi: 10.1111/petr.13041. Epub 2017 Sep 17.


Analysis of patient-detected breast cancer recurrence.

Kapoor T, Wrenn S, Callas P, James TA.

Breast Dis. 2017;37(2):77-82. doi: 10.3233/BD-170288.


Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action.

Steinman JB, Santarossa CC, Miller RM, Yu LS, Serpinskaya AS, Furukawa H, Morimoto S, Tanaka Y, Nishitani M, Asano M, Zalyte R, Ondrus AE, Johnson AG, Ye F, Nachury MV, Fukase Y, Aso K, Foley MA, Gelfand VI, Chen JK, Carter AP, Kapoor TM.

Elife. 2017 May 19;6. pii: e25174. doi: 10.7554/eLife.25174.


The mechanics of microtubule networks in cell division.

Forth S, Kapoor TM.

J Cell Biol. 2017 Jun 5;216(6):1525-1531. doi: 10.1083/jcb.201612064. Epub 2017 May 10. Review.


Low prevalence of Pneumocystis pneumonia in hospitalized patients with systemic lupus erythematosus: review of a clinical data warehouse.

Kapoor TM, Mahadeshwar P, Nguyen S, Li J, Kapoor S, Bathon J, Giles J, Askanase A.

Lupus. 2017 Dec;26(14):1473-1482. doi: 10.1177/0961203317703494. Epub 2017 Apr 11.


Metaphase Spindle Assembly.

Kapoor TM.

Biology (Basel). 2017 Feb 3;6(1). pii: E8. doi: 10.3390/biology6010008. Review.


Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis.

Kawashima SA, Chen Z, Aoi Y, Patgiri A, Kobayashi Y, Nurse P, Kapoor TM.

Cell. 2016 Oct 6;167(2):512-524.e14. doi: 10.1016/j.cell.2016.08.070. Epub 2016 Sep 22.


Global Distribution of Businesses Marketing Stem Cell-Based Interventions.

Berger I, Ahmad A, Bansal A, Kapoor T, Sipp D, Rasko JEJ.

Cell Stem Cell. 2016 Aug 4;19(2):158-162. doi: 10.1016/j.stem.2016.07.015.


Near-atomic cryo-EM structure of PRC1 bound to the microtubule.

Kellogg EH, Howes S, Ti SC, Ramírez-Aportela E, Kapoor TM, Chacón P, Nogales E.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9430-9. doi: 10.1073/pnas.1609903113. Epub 2016 Aug 4.


The structured core of human β tubulin confers isotype-specific polymerization properties.

Pamula MC, Ti SC, Kapoor TM.

J Cell Biol. 2016 May 23;213(4):425-33. doi: 10.1083/jcb.201603050. Epub 2016 May 16.


Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends.

Ti SC, Pamula MC, Howes SC, Duellberg C, Cade NI, Kleiner RE, Forth S, Surrey T, Nogales E, Kapoor TM.

Dev Cell. 2016 Apr 4;37(1):72-84. doi: 10.1016/j.devcel.2016.03.003.


Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity.

See SK, Hoogendoorn S, Chung AH, Ye F, Steinman JB, Sakata-Kato T, Miller RM, Cupido T, Zalyte R, Carter AP, Nachury MV, Kapoor TM, Chen JK.

ACS Chem Biol. 2016 Jan 15;11(1):53-60. doi: 10.1021/acschembio.5b00895. Epub 2015 Nov 11.


Measuring Pushing and Braking Forces Generated by Ensembles of Kinesin-5 Crosslinking Two Microtubules.

Shimamoto Y, Forth S, Kapoor TM.

Dev Cell. 2015 Sep 28;34(6):669-81. doi: 10.1016/j.devcel.2015.08.017.


Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response.

Kleiner RE, Verma P, Molloy KR, Chait BT, Kapoor TM.

Nat Chem Biol. 2015 Oct;11(10):807-14. doi: 10.1038/nchembio.1908. Epub 2015 Sep 7.


Reconstitution of the augmin complex provides insights into its architecture and function.

Hsia KC, Wilson-Kubalek EM, Dottore A, Hao Q, Tsai KL, Forth S, Shimamoto Y, Milligan RA, Kapoor TM.

Nat Cell Biol. 2014 Sep;16(9):852-63. doi: 10.1038/ncb3030. Epub 2014 Aug 31.


Direct kinetochore-spindle pole connections are not required for chromosome segregation.

Sikirzhytski V, Magidson V, Steinman JB, He J, Le Berre M, Tikhonenko I, Ault JG, McEwen BF, Chen JK, Sui H, Piel M, Kapoor TM, Khodjakov A.

J Cell Biol. 2014 Jul 21;206(2):231-43. doi: 10.1083/jcb.201401090. Epub 2014 Jul 14.


The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment.

He M, Subramanian R, Bangs F, Omelchenko T, Liem KF Jr, Kapoor TM, Anderson KV.

Nat Cell Biol. 2014 Jul;16(7):663-72. doi: 10.1038/ncb2988. Epub 2014 Jun 22.


DrugTargetSeqR: a genomics- and CRISPR-Cas9-based method to analyze drug targets.

Kasap C, Elemento O, Kapoor TM.

Nat Chem Biol. 2014 Aug;10(8):626-8. doi: 10.1038/nchembio.1551. Epub 2014 Jun 15.


MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress.

Rosenbaum M, Andreani V, Kapoor T, Herp S, Flach H, Duchniewicz M, Grosschedl R.

Genes Dev. 2014 Jun 1;28(11):1165-78. doi: 10.1101/gad.240762.114.


Asymmetric friction of nonmotor MAPs can lead to their directional motion in active microtubule networks.

Forth S, Hsia KC, Shimamoto Y, Kapoor TM.

Cell. 2014 Apr 10;157(2):420-432. doi: 10.1016/j.cell.2014.02.018.


Using 'biased-privileged' scaffolds to identify lysine methyltransferase inhibitors.

Kashyap S, Sandler J, Peters U, Martinez EJ, Kapoor TM.

Bioorg Med Chem. 2014 Apr 1;22(7):2253-60. doi: 10.1016/j.bmc.2014.02.024. Epub 2014 Feb 28.


Dissecting the first and the second meiotic divisions using a marker-less drug-hypersensitive fission yeast.

Aoi Y, Sato M, Sutani T, Shirahige K, Kapoor TM, Kawashima SA.

Cell Cycle. 2014;13(8):1327-34. doi: 10.4161/cc.28294. Epub 2014 Mar 3.


Micromechanics of the vertebrate meiotic spindle examined by stretching along the pole-to-pole axis.

Takagi J, Itabashi T, Suzuki K, Shimamoto Y, Kapoor TM, Ishiwata S.

Biophys J. 2014 Feb 4;106(3):735-40. doi: 10.1016/j.bpj.2013.12.033.


Slipping past the spindle assembly checkpoint.

Subramanian R, Kapoor TM.

Nat Cell Biol. 2013 Nov;15(11):1261-3. doi: 10.1038/ncb2876.


Using micromanipulation to analyze control of vertebrate meiotic spindle size.

Takagi J, Itabashi T, Suzuki K, Kapoor TM, Shimamoto Y, Ishiwata S.

Cell Rep. 2013 Oct 17;5(1):44-50. doi: 10.1016/j.celrep.2013.09.021. Epub 2013 Oct 10.


Centrosome repositioning in T cells is biphasic and driven by microtubule end-on capture-shrinkage.

Yi J, Wu X, Chung AH, Chen JK, Kapoor TM, Hammer JA.

J Cell Biol. 2013 Sep 2;202(5):779-92. doi: 10.1083/jcb.201301004. Epub 2013 Aug 26.


Bumping up kinase activity with an ATP-derived neo-substrate.

Kleiner RE, Kapoor TM.

Cell. 2013 Aug 15;154(4):716-8. doi: 10.1016/j.cell.2013.07.043.


Site-specific chemistry on the microtubule polymer.

Kleiner RE, Ti SC, Kapoor TM.

J Am Chem Soc. 2013 Aug 28;135(34):12520-3. doi: 10.1021/ja405199h. Epub 2013 Aug 15.


Marking and measuring single microtubules by PRC1 and kinesin-4.

Subramanian R, Ti SC, Tan L, Darst SA, Kapoor TM.

Cell. 2013 Jul 18;154(2):377-90. doi: 10.1016/j.cell.2013.06.021. Erratum in: Cell. 2013 Nov 21;155(5):1188.

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