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The implementation of the bioequivalence certification policy in Chile: An analysis of market authorization data.

Kaplan WA, Cárdenas J, Mansilla C, Tobar T, Wirtz VJ.

PLoS One. 2019 May 29;14(5):e0217334. doi: 10.1371/journal.pone.0217334. eCollection 2019.


Evaluation of the effects of a generic substitution policy implemented in Chile.

Mansilla C, Cárdenas J, Kaplan WA, Wirtz VJ, Kuhn-Barrientos L, Ortíz de Zárate M, Tobar T, Herrera CA.

BMJ Glob Health. 2019 Mar 4;2(Suppl 3):e000922. doi: 10.1136/bmjgh-2018-000922. eCollection 2017.


A perspective on global access to insulin: a descriptive study of the market, trade flows and prices.

Beran D, Laing RO, Kaplan W, Knox R, Sharma A, Wirtz VJ, Frye J, Ewen M.

Diabet Med. 2019 Jun;36(6):726-733. doi: 10.1111/dme.13947. Epub 2019 Apr 7.


Modular Total Synthesis and Cell-Based Anticancer Activity Evaluation of Ouabagenin and Other Cardiotonic Steroids with Varying Degrees of Oxygenation.

Khatri HR, Bhattarai B, Kaplan W, Li Z, Curtis Long MJ, Aye Y, Nagorny P.

J Am Chem Soc. 2019 Mar 27;141(12):4849-4860. doi: 10.1021/jacs.8b12870. Epub 2019 Mar 14.


Retrospective analysis of long-term gastrointestinal symptoms after Clostridium difficile infection in a nonelderly cohort.

Barlam TF, Soria-Saucedo R, Ameli O, Cabral HJ, Kaplan WA, Kazis LE.

PLoS One. 2018 Dec 17;13(12):e0209152. doi: 10.1371/journal.pone.0209152. eCollection 2018.


The Medical Genome Reference Bank: a whole-genome data resource of 4000 healthy elderly individuals. Rationale and cohort design.

Lacaze P, Pinese M, Kaplan W, Stone A, Brion MJ, Woods RL, McNamara M, McNeil JJ, Dinger ME, Thomas DM.

Eur J Hum Genet. 2019 Feb;27(2):308-316. doi: 10.1038/s41431-018-0279-z. Epub 2018 Oct 24.


Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer.

Tsoli M, Wadham C, Pinese M, Failes T, Joshi S, Mould E, Yin JX, Gayevskiy V, Kumar A, Kaplan W, Ekert PG, Saletta F, Franshaw L, Liu J, Gifford A, Weber MA, Rodriguez M, Cohn RJ, Arndt G, Tyrrell V, Haber M, Trahair T, Marshall GM, McDonald K, Cowley MJ, Ziegler DS.

Cancer Biol Ther. 2018;19(12):1078-1087. doi: 10.1080/15384047.2018.1491498. Epub 2018 Oct 9.


The Open Insulin Project: A Case Study for 'Biohacked' Medicines.

Gallegos JE, Boyer C, Pauwels E, Kaplan WA, Peccoud J.

Trends Biotechnol. 2018 Dec;36(12):1211-1218. doi: 10.1016/j.tibtech.2018.07.009. Epub 2018 Sep 13. Review.


Is Taiwan's National Health Insurance a perfect system? Problems related to health care utilization of the aboriginal population in rural townships.

Lee YT, Lee YH, Kaplan WA.

Int J Health Plann Manage. 2019 Jan;34(1):e6-e10. doi: 10.1002/hpm.2653. Epub 2018 Sep 13.


The growth hormone-insulin-like growth factor-I axis in the diagnosis and treatment of growth disorders.

Blum WF, Alherbish A, Alsagheir A, El Awwa A, Kaplan W, Koledova E, Savage MO.

Endocr Connect. 2018 Jun;7(6):R212-R222. doi: 10.1530/EC-18-0099. Epub 2018 May 3. Review.


Challenges constraining insulin access in Nepal-a country with no local insulin production.

Sharma A, Bhandari PM, Neupane D, Kaplan WA, Mishra SR.

Int Health. 2018 May 1;10(3):182-190. doi: 10.1093/inthealth/ihy012.


Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance.

Fazakerley DJ, Chaudhuri R, Yang P, Maghzal GJ, Thomas KC, Krycer JR, Humphrey SJ, Parker BL, Fisher-Wellman KH, Meoli CC, Hoffman NJ, Diskin C, Burchfield JG, Cowley MJ, Kaplan W, Modrusan Z, Kolumam G, Yang JY, Chen DL, Samocha-Bonet D, Greenfield JR, Hoehn KL, Stocker R, James DE.

Elife. 2018 Feb 6;7. pii: e32111. doi: 10.7554/eLife.32111.


Hyperglycaemic hyperosmolar syndrome in a 5-year-old girl with newly diagnosed type 2 diabetes mellitus.

Al Hassani N, Kaplan W.

Diabetes Metab. 2019 Oct;45(5):488-489. doi: 10.1016/j.diabet.2017.11.004. Epub 2017 Nov 25. No abstract available.


Effect of Growth Hormone on Final Height in Children with Idiopathic Short Stature: A UAE, Eastern Region Experience.

Mreish S, Kaplan W, Chedid F.

Oman Med J. 2017 Nov;32(6):467-470. doi: 10.5001/omj.2017.90.


Comparison of continuous glucose monitoring in adolescents with type 1 diabetes: Ramadan versus non-Ramadan.

Kaplan W, Afandi B, Al Hassani N, Hadi S, Zoubeidi T.

Diabetes Res Clin Pract. 2017 Dec;134:178-182. doi: 10.1016/j.diabres.2017.10.010. Epub 2017 Oct 20.


Disproportionate Exposure to Antibiotics in Children at Risk for Invasive Pneumococcal Disease: Potential for Emerging Resistance and Opportunity for Antibiotic Stewardship.

Barlam TF, Morgan JR, Kaplan WA, Outterson K, Pelton SI.

J Pediatric Infect Dis Soc. 2019 Mar 28;8(1):63-65. doi: 10.1093/jpids/pix070.


Trade in medicines and the public's health: a time series analysis of import disruptions during the 2015 India-Nepal border blockade.

Sharma A, Mishra SR, Kaplan WA.

Global Health. 2017 Aug 22;13(1):61. doi: 10.1186/s12992-017-0282-0.


Optical control of capacitance in a metal-insulator-semiconductor diode with embedded metal nanoparticles.

Mikhelashvili V, Ankonina G, Kauffmann Y, Atiya G, Kaplan WD, Padmanabhan R, Eisenstein G.

J Appl Phys. 2017 Jun 7;121(21):214504. doi: 10.1063/1.4983760. Epub 2017 Jun 6.


Challenges constraining access to insulin in the private-sector market of Delhi, India.

Sharma A, Kaplan WA.

BMJ Glob Health. 2016 Oct 12;1(3):e000112. doi: 10.1136/bmjgh-2016-000112. eCollection 2016.


Comparison of medicines management strategies in insurance schemes in middle-income countries: four case studies.

Kaplan WA, Ashigbie PG, Brooks MI, Wirtz VJ.

J Pharm Policy Pract. 2017 May 16;10:17. doi: 10.1186/s40545-017-0105-y. eCollection 2017.


Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells.

Kräutler NJ, Suan D, Butt D, Bourne K, Hermes JR, Chan TD, Sundling C, Kaplan W, Schofield P, Jackson J, Basten A, Christ D, Brink R.

J Exp Med. 2017 May 1;214(5):1259-1267. doi: 10.1084/jem.20161533. Epub 2017 Mar 31.


Correlation between pre-ramadan glycemic control and subsequent glucose fluctuation during fasting in adolescents with Type 1 diabetes.

Afandi B, Kaplan W, Al Hassani N, Hadi S, Mohamed A.

J Endocrinol Invest. 2017 Jul;40(7):741-744. doi: 10.1007/s40618-017-0633-y. Epub 2017 Feb 26.


Prices and availability of locally produced and imported medicines in Ethiopia and Tanzania.

Ewen M, Kaplan W, Gedif T, Justin-Temu M, Vialle-Valentin C, Mirza Z, Regeer B, Zweekhorst M, Laing R.

J Pharm Policy Pract. 2017 Jan 16;10:7. doi: 10.1186/s40545-016-0095-1. eCollection 2017.


Growing concerns and controversies to Taiwan's National Health Insurance-what are the lessons from mainland China, South Korea and Singapore?

Lee YH, Ang TFA, Chiang TC, Kaplan WA.

Int J Health Plann Manage. 2018 Jan;33(1):e357-e366. doi: 10.1002/hpm.2387. Epub 2016 Oct 10.


Response by Wirtz et al to Letter Regarding Article, "Access to Medications for Cardiovascular Diseases in Low- and Middle-Income Countries".

Wirtz VJ, Kaplan WA, Kwan GF, Laing RO.

Circulation. 2016 Oct 4;134(14):e305-e306. No abstract available.


The primary immune response to Vaccinia virus vaccination includes cells with a distinct cytotoxic effector CD4 T-cell phenotype.

Munier CML, van Bockel D, Bailey M, Ip S, Xu Y, Alcantara S, Liu SM, Denyer G, Kaplan W; PHIIDO Study group, Suzuki K, Croft N, Purcell A, Tscharke D, Cooper DA, Kent SJ, Zaunders JJ, Kelleher AD.

Vaccine. 2016 Oct 17;34(44):5251-5261. doi: 10.1016/j.vaccine.2016.09.009. Epub 2016 Sep 14.


Diagnosis and management of growth disorders in Gulf Cooperation Council (GCC) countries: Current procedures and key recommendations for best practice.

Al Herbish AS, Almutair A, Bin Abbas B, Alsagheir A, Alqahtani M, Kaplan W, Deeb A, El-Awwa A, Al Khawari M, Koledova E, Savage MO.

Int J Pediatr Adolesc Med. 2016 Sep;3(3):91-102. doi: 10.1016/j.ijpam.2016.07.002. Epub 2016 Aug 10. Review.


Low Serum Testosterone Level Predisposes to Artificial Urinary Sphincter Cuff Erosion.

Hofer MD, Morey AF, Sheth K, Tausch TJ, Siegel J, Cordon BH, Bury MI, Cheng EY, Sharma AK, Gonzalez CM, Kaplan WE, Kavoussi NL, Klein A, Roehrborn CG.

Urology. 2016 Nov;97:245-249. doi: 10.1016/j.urology.2016.04.065. Epub 2016 Jul 20.


The global intellectual property ecosystem for insulin and its public health implications: an observational study.

Kaplan WA, Beall RF.

J Pharm Policy Pract. 2016 Jul 19;10:3. doi: 10.1186/s40545-016-0072-8. eCollection 2017.


Modeling duration of time lived in a residence, a community and mobility in rural areas of Merced and Ventura, California to assess potential health risks to airborne contaminants.

Driver J, Price P, vanWesenbeeck I, Kaplan W, Holden L, Ross J, Landenberger B.

Sci Total Environ. 2016 Nov 1;569-570:861-868. doi: 10.1016/j.scitotenv.2016.06.139. Epub 2016 Jul 16.


Endoscopic ureterocele-otomy - Retrograde incision from orifice (RIO) of urethral segment of ureterocele and extending to bladder neck is a feasible and simple procedure.

Maizels M, Liu D, Gong EM, Kaplan WE, Cheng EY.

J Pediatr Urol. 2016 Jun;12(3):137-8. doi: 10.1016/j.jpurol.2016.05.010. Epub 2016 Jun 3. No abstract available.


Concise Enantioselective Total Synthesis of Cardiotonic Steroids 19-Hydroxysarmentogenin and Trewianin Aglycone.

Kaplan W, Khatri HR, Nagorny P.

J Am Chem Soc. 2016 Jun 8;138(22):7194-8. doi: 10.1021/jacs.6b04029. Epub 2016 May 27.


Access to Medications for Cardiovascular Diseases in Low- and Middle-Income Countries.

Wirtz VJ, Kaplan WA, Kwan GF, Laing RO.

Circulation. 2016 May 24;133(21):2076-85. doi: 10.1161/CIRCULATIONAHA.115.008722. Review.


Liberating data to combat NCDs.

Mishra SR, Sharma A, Kaplan WA, Adhikari B, Neupane D.

Lancet Diabetes Endocrinol. 2016 Jun;4(6):482-3. doi: 10.1016/S2213-8587(16)30054-7. No abstract available.


Role of the private sector in vaccination service delivery in India: evidence from private-sector vaccine sales data, 2009-12.

Sharma A, Kaplan WA, Chokshi M, Zodpey SP.

Health Policy Plan. 2016 Sep;31(7):884-96. doi: 10.1093/heapol/czw008. Epub 2016 Mar 14.


Is Patent "Evergreening" Restricting Access to Medicine/Device Combination Products?

Beall RF, Nickerson JW, Kaplan WA, Attaran A.

PLoS One. 2016 Feb 24;11(2):e0148939. doi: 10.1371/journal.pone.0148939. eCollection 2016.


Insulin patents and market exclusivities: unresolved issues.

Kaplan W, Laing R, Ewen M, Beran D.

Lancet Diabetes Endocrinol. 2016 Feb;4(2):98. doi: 10.1016/S2213-8587(15)00496-9. No abstract available.


ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.

Gallego-Ortega D, Ledger A, Roden DL, Law AM, Magenau A, Kikhtyak Z, Cho C, Allerdice SL, Lee HJ, Valdes-Mora F, Herrmann D, Salomon R, Young AI, Lee BY, Sergio CM, Kaplan W, Piggin C, Conway JR, Rabinovich B, Millar EK, Oakes SR, Chtanova T, Swarbrick A, Naylor MJ, O'Toole S, Green AR, Timpson P, Gee JM, Ellis IO, Clark SJ, Ormandy CJ.

PLoS Biol. 2015 Dec 30;13(12):e1002330. doi: 10.1371/journal.pbio.1002330. eCollection 2015 Dec.


Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche.

Lawson MA, McDonald MM, Kovacic N, Hua Khoo W, Terry RL, Down J, Kaplan W, Paton-Hough J, Fellows C, Pettitt JA, Neil Dear T, Van Valckenborgh E, Baldock PA, Rogers MJ, Eaton CL, Vanderkerken K, Pettit AR, Quinn JM, Zannettino AC, Phan TG, Croucher PI.

Nat Commun. 2015 Dec 3;6:8983. doi: 10.1038/ncomms9983.


Concise Enantioselective Synthesis of Oxygenated Steroids via Sequential Copper(II)-Catalyzed Michael Addition/Intramolecular Aldol Cyclization Reactions.

Cichowicz NR, Kaplan W, Khomutnyk Y, Bhattarai B, Sun Z, Nagorny P.

J Am Chem Soc. 2015 Nov 18;137(45):14341-8. doi: 10.1021/jacs.5b08528. Epub 2015 Nov 10.


Genetic characteristics, clinical spectrum, and incidence of neonatal diabetes in the Emirate of AbuDhabi, United Arab Emirates.

Deeb A, Habeb A, Kaplan W, Attia S, Hadi S, Osman A, Al-Jubeh J, Flanagan S, DeFranco E, Ellard S.

Am J Med Genet A. 2016 Mar;170(3):602-9. doi: 10.1002/ajmg.a.37419. Epub 2015 Oct 13.


MATERIALS SCIENCE. The mechanism of crystal deformation.

Kaplan WD.

Science. 2015 Sep 4;349(6252):1059-60. doi: 10.1126/science.aac9623. No abstract available.


Blood glucose fluctuation during Ramadan fasting in adolescents with type 1 diabetes: findings of continuous glucose monitoring.

Kaplan W, Afandi B.

Diabetes Care. 2015 Oct;38(10):e162-3. doi: 10.2337/dc15-1108. Epub 2015 Aug 20. No abstract available.


Recognizing Differences in Hospital Quality Performance for Pediatric Inpatient Care.

Berry JG, Zaslavsky AM, Toomey SL, Chien AT, Jang J, Bryant MC, Klein DJ, Kaplan WJ, Schuster MA.

Pediatrics. 2015 Aug;136(2):251-62. doi: 10.1542/peds.2014-3131. Epub 2015 Jul 13.


MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene.

Phua YW, Nguyen A, Roden DL, Elsworth B, Deng N, Nikolic I, Yang J, Mcfarland A, Russell R, Kaplan W, Cowley MJ, Nair R, Zotenko E, O'Toole S, Tan SX, James DE, Clark SJ, Kouros-Mehr H, Swarbrick A.

Breast Cancer Res. 2015 Jun 13;17:83. doi: 10.1186/s13058-015-0593-0.


T follicular helper cells have distinct modes of migration and molecular signatures in naive and memory immune responses.

Suan D, Nguyen A, Moran I, Bourne K, Hermes JR, Arshi M, Hampton HR, Tomura M, Miwa Y, Kelleher AD, Kaplan W, Deenick EK, Tangye SG, Brink R, Chtanova T, Phan TG.

Immunity. 2015 Apr 21;42(4):704-18. doi: 10.1016/j.immuni.2015.03.002. Epub 2015 Mar 31.


ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype.

Junankar S, Baker LA, Roden DL, Nair R, Elsworth B, Gallego-Ortega D, Lacaze P, Cazet A, Nikolic I, Teo WS, Yang J, McFarland A, Harvey K, Naylor MJ, Lakhani SR, Simpson PT, Raghavendra A, Saunus J, Madore J, Kaplan W, Ormandy C, Millar EK, O'Toole S, Yun K, Swarbrick A.

Nat Commun. 2015 Mar 27;6:6548. doi: 10.1038/ncomms7548.


Androgen supplementation in rats increases the inflammatory response and prolongs urethral healing.

Hofer MD, Cheng EY, Bury MI, Xu W, Hong SJ, Kaplan WE, Sharma AK.

Urology. 2015 Mar;85(3):691-7. doi: 10.1016/j.urology.2014.11.025.


Implications of private sector Hib vaccine coverage for the introduction of public sector Hib-containing pentavalent vaccine in India: evidence from retrospective time series data.

Sharma A, Kaplan WA, Chokshi M, Hasan Farooqui H, Zodpey SP.

BMJ Open. 2015 Feb 23;5(2):e007038. doi: 10.1136/bmjopen-2014-007038.


mRNA Structural constraints on EBNA1 synthesis impact on in vivo antigen presentation and early priming of CD8+ T cells.

Tellam JT, Zhong J, Lekieffre L, Bhat P, Martinez M, Croft NP, Kaplan W, Tellam RL, Khanna R.

PLoS Pathog. 2014 Oct 9;10(10):e1004423. doi: 10.1371/journal.ppat.1004423. eCollection 2014 Oct.

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