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Items: 1 to 50 of 403

1.

Corrigendum: STAT4 is required for the generation of Th1 and Th2, but not Th17 immune responses during monophosphoryl lipid A adjuvant activity.

Varikuti S, Oghumu S, Natarajan G, Kimble J, Sperling RH, Moretti E, Kaplan MH, Satoskar AR.

Int Immunol. 2018 Jun 25. doi: 10.1093/intimm/dxy037. [Epub ahead of print] No abstract available.

PMID:
29939272
2.

Effector T Helper Cell Subsets in Inflammatory Bowel Diseases.

Imam T, Park S, Kaplan MH, Olson MR.

Front Immunol. 2018 Jun 1;9:1212. doi: 10.3389/fimmu.2018.01212. eCollection 2018. Review.

3.

Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms.

Ocana JA, Romer E, Sahu R, Pawelzik SC, FitzGerald GA, Kaplan MH, Travers JB.

J Immunol. 2018 Jun 15;200(12):4004-4011. doi: 10.4049/jimmunol.1701145. Epub 2018 Apr 25.

PMID:
29695417
4.

IRF4 Modulates CD8+ T Cell Sensitivity to IL-2 Family Cytokines.

Huang S, Shen Y, Pham D, Jiang L, Wang Z, Kaplan MH, Zhang G, Sun J.

Immunohorizons. 2017 Aug 1;1(6):92-100. doi: 10.4049/immunohorizons.1700020. Epub 2017 Aug 14.

5.

Mechanism for initiation of food allergy: Dependence on skin barrier mutations and environmental allergen costimulation.

Walker MT, Green JE, Ferrie RP, Queener AM, Kaplan MH, Cook-Mills JM.

J Allergy Clin Immunol. 2018 May;141(5):1711-1725.e9. doi: 10.1016/j.jaci.2018.02.003. Epub 2018 Feb 15. Erratum in: J Allergy Clin Immunol. 2018 Jul;142(1):339.

PMID:
29454836
6.

Phenotyping acute and chronic atopic dermatitis-like lesions in Stat6VT mice identifies a role for IL-33 in disease pathogenesis.

DaSilva-Arnold SC, Thyagarajan A, Seymour LJ, Yi Q, Bradish JR, Al-Hassani M, Zhou H, Perdue NJ, Nemeth V, Krbanjevic A, Serezani APM, Olson MR, Spandau DF, Travers JB, Kaplan MH, Turner MJ.

Arch Dermatol Res. 2018 Apr;310(3):197-207. doi: 10.1007/s00403-018-1807-y. Epub 2018 Jan 24.

PMID:
29368135
7.

Neonatal hyperoxia promotes asthma-like features through IL-33-dependent ILC2 responses.

Cheon IS, Son YM, Jiang L, Goplen NP, Kaplan MH, Limper AH, Kita H, Paczesny S, Prakash YS, Tepper R, Ahlfeld SK, Sun J.

J Allergy Clin Immunol. 2017 Dec 15. pii: S0091-6749(17)32871-3. doi: 10.1016/j.jaci.2017.11.025. [Epub ahead of print]

PMID:
29253513
8.

Rapid molecular assays to study human centromere genomics.

Contreras-Galindo R, Fischer S, Saha AK, Lundy JD, Cervantes PW, Mourad M, Wang C, Qian B, Dai M, Meng F, Chinnaiyan A, Omenn GS, Kaplan MH, Markovitz DM.

Genome Res. 2017 Dec;27(12):2040-2049. doi: 10.1101/gr.219709.116. Epub 2017 Nov 15.

9.

STAT4 Regulates the CD8+ Regulatory T Cell/T Follicular Helper Cell Axis and Promotes Atherogenesis in Insulin-Resistant Ldlr-/- Mice.

Taghavie-Moghadam PL, Waseem TC, Hattler J, Glenn LM, Dobrian AD, Kaplan MH, Yang Y, Nurieva R, Nadler JL, Galkina EV.

J Immunol. 2017 Nov 15;199(10):3453-3465. doi: 10.4049/jimmunol.1601429. Epub 2017 Oct 20.

PMID:
29055004
10.

Specifically differentiated T cell subset promotes tumor immunity over fatal immunity.

Ramadan A, Griesenauer B, Adom D, Kapur R, Hanenberg H, Liu C, Kaplan MH, Paczesny S.

J Exp Med. 2017 Dec 4;214(12):3577-3596. doi: 10.1084/jem.20170041. Epub 2017 Oct 16.

11.

Susceptibility of Human Endogenous Retrovirus Type K to Reverse Transcriptase Inhibitors.

Contreras-Galindo R, Dube D, Fujinaga K, Kaplan MH, Markovitz DM.

J Virol. 2017 Nov 14;91(23). pii: e01309-17. doi: 10.1128/JVI.01309-17. Print 2017 Dec 1.

12.

A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function.

Kälin S, Becker M, Ott VB, Serr I, Hosp F, Mollah MMH, Keipert S, Lamp D, Rohner-Jeanrenaud F, Flynn VK, Scherm MG, Nascimento LFR, Gerlach K, Popp V, Dietzen S, Bopp T, Krishnamurthy P, Kaplan MH, Serrano M, Woods SC, Tripal P, Palmisano R, Jastroch M, Blüher M, Wolfrum C, Weigmann B, Ziegler AG, Mann M, Tschöp MH, Daniel C.

Cell Metab. 2017 Sep 5;26(3):475-492.e7. doi: 10.1016/j.cmet.2017.08.008.

PMID:
28877454
13.

Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells.

Rauber S, Luber M, Weber S, Maul L, Soare A, Wohlfahrt T, Lin NY, Dietel K, Bozec A, Herrmann M, Kaplan MH, Weigmann B, Zaiss MM, Fearon U, Veale DJ, Cañete JD, Distler O, Rivellese F, Pitzalis C, Neurath MF, McKenzie ANJ, Wirtz S, Schett G, Distler JHW, Ramming A.

Nat Med. 2017 Aug;23(8):938-944. doi: 10.1038/nm.4373. Epub 2017 Jul 17.

14.

Poly-ADP ribose polymerase-14 limits severity of allergic skin disease.

Krishnamurthy P, Da-Silva-Arnold S, Turner MJ, Travers JB, Kaplan MH.

Immunology. 2017 Nov;152(3):451-461. doi: 10.1111/imm.12782. Epub 2017 Jul 27.

PMID:
28653395
15.

Bcl6 promotes follicular helper T-cell differentiation and PD-1 expression in a Blimp1-independent manner in mice.

Xie MM, Koh BH, Hollister K, Wu H, Sun J, Kaplan MH, Dent AL.

Eur J Immunol. 2017 Jul;47(7):1136-1141. doi: 10.1002/eji.201747034.

16.

Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production.

Olson MR, Ulrich BJ, Hummel SA, Khan I, Meuris B, Cherukuri Y, Dent AL, Janga SC, Kaplan MH.

J Immunol. 2017 Jun 1;198(11):4352-4359. doi: 10.4049/jimmunol.1601792. Epub 2017 May 3.

17.

Key Role of STAT4 Deficiency in the Hematopoietic Compartment in Insulin Resistance and Adipose Tissue Inflammation.

Dobrian AD, Ma K, Glenn LM, Hatcher MA, Haynes BA, Lehrer EJ, Kaplan MH, Nadler JL.

Mediators Inflamm. 2017;2017:5420718. doi: 10.1155/2017/5420718. Epub 2017 Mar 16.

18.

STAT Transcription Factors in T Cell Control of Health and Disease.

Goswami R, Kaplan MH.

Int Rev Cell Mol Biol. 2017;331:123-180. doi: 10.1016/bs.ircmb.2016.09.012. Epub 2016 Nov 9. Review.

PMID:
28325211
19.

Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.

Cheung KL, Zhang F, Jaganathan A, Sharma R, Zhang Q, Konuma T, Shen T, Lee JY, Ren C, Chen CH, Lu G, Olson MR, Zhang W, Kaplan MH, Littman DR, Walsh MJ, Xiong H, Zeng L, Zhou MM.

Mol Cell. 2017 Mar 16;65(6):1068-1080.e5. doi: 10.1016/j.molcel.2016.12.022. Epub 2017 Mar 3.

20.

STAT3 Activation Impairs the Stability of Th9 Cells.

Ulrich BJ, Verdan FF, McKenzie AN, Kaplan MH, Olson MR.

J Immunol. 2017 Mar 15;198(6):2302-2309. doi: 10.4049/jimmunol.1601624. Epub 2017 Jan 30.

21.

Etv5 Regulates IL-10 Production in Th Cells.

Koh B, Hufford MM, Sun X, Kaplan MH.

J Immunol. 2017 Mar 1;198(5):2165-2171. doi: 10.4049/jimmunol.1600801. Epub 2017 Jan 18.

22.

Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors.

Kobayashi M, Nabinger SC, Bai Y, Yoshimoto M, Gao R, Chen S, Yao C, Dong Y, Zhang L, Rodriguez S, Yashiro-Ohtani Y, Pear WS, Carlesso N, Yoder MC, Kapur R, Kaplan MH, Daniel Lacorazza H, Zhang ZY, Liu Y.

Stem Cells. 2017 Apr;35(4):1053-1064. doi: 10.1002/stem.2559. Epub 2017 Jan 19.

23.

Th9 cells in immunity and immunopathological diseases.

Neurath MF, Kaplan MH.

Semin Immunopathol. 2017 Jan;39(1):1-4. doi: 10.1007/s00281-016-0611-z. Epub 2016 Nov 29. No abstract available.

PMID:
27900451
24.

The transcription factor network in Th9 cells.

Kaplan MH.

Semin Immunopathol. 2017 Jan;39(1):11-20. doi: 10.1007/s00281-016-0600-2. Epub 2016 Nov 11. Review.

25.

Increased Th2 activity and diminished skin barrier function cooperate in allergic skin inflammation.

Sehra S, Krishnamurthy P, Koh B, Zhou HM, Seymour L, Akhtar N, Travers JB, Turner MJ, Kaplan MH.

Eur J Immunol. 2016 Nov;46(11):2609-2613. doi: 10.1002/eji.201646421. Epub 2016 Aug 29.

26.

STAT4 is required for the generation of Th1 and Th2, but not Th17 immune responses during monophosphoryl lipid A adjuvant activity.

Varikuti S, Oghumu S, Natarajan G, Kimble J, Sperling RH, Moretti E, Kaplan MH, Satoskar AR.

Int Immunol. 2016 Nov;28(11):565-570. Epub 2016 Aug 30.

27.

STAT6 and PARP Family Members in the Development of T Cell-dependent Allergic Inflammation.

Krishnamurthy P, Kaplan MH.

Immune Netw. 2016 Aug;16(4):201-10. doi: 10.4110/in.2016.16.4.201. Epub 2016 Aug 23. Review.

28.

IL-4 impairs wound healing potential in the skin by repressing fibronectin expression.

Serezani APM, Bozdogan G, Sehra S, Walsh D, Krishnamurthy P, Sierra Potchanant EA, Nalepa G, Goenka S, Turner MJ, Spandau DF, Kaplan MH.

J Allergy Clin Immunol. 2017 Jan;139(1):142-151.e5. doi: 10.1016/j.jaci.2016.07.012. Epub 2016 Aug 20.

29.

The ETS Family Transcription Factors Etv5 and PU.1 Function in Parallel To Promote Th9 Cell Development.

Koh B, Hufford MM, Pham D, Olson MR, Wu T, Jabeen R, Sun X, Kaplan MH.

J Immunol. 2016 Sep 15;197(6):2465-72. doi: 10.4049/jimmunol.1502383. Epub 2016 Aug 5.

30.

Mast Cells Regulate Epidermal Barrier Function and the Development of Allergic Skin Inflammation.

Sehra S, Serezani APM, Ocaña JA, Travers JB, Kaplan MH.

J Invest Dermatol. 2016 Jul;136(7):1429-1437. doi: 10.1016/j.jid.2016.03.019. Epub 2016 Mar 25.

31.

STAT3 Impairs STAT5 Activation in the Development of IL-9-Secreting T Cells.

Olson MR, Verdan FF, Hufford MM, Dent AL, Kaplan MH.

J Immunol. 2016 Apr 15;196(8):3297-304. doi: 10.4049/jimmunol.1501801. Epub 2016 Mar 14.

32.

Correction: The TNF-Family Ligand TL1A and Its Receptor DR3 Promote T Cell-Mediated Allergic Immunopathology by Enhancing Differentiation and Pathogenicity of IL-9-Producing T Cells.

Richard AC, Tan C, Hawley ET, Gomez-Rodriguez J, Goswami R, Yang XP, Cruz AC, Penumetcha P, Hayes ET, Pelletier M, Gabay O, Walsh M, Ferdinand JR, Keane-Myers A, Choi Y, O'Shea JJ, Al-Shamkhani A, Kaplan MH, Gery I, Siegel RM, Meylan F.

J Immunol. 2015 Dec 15;195(12):5839-40. doi: 10.4049/jimmunol.1502026. No abstract available.

33.

Increased prevalence of airway reactivity in children with eosinophilic esophagitis.

Krupp NL, Sehra S, Slaven JE, Kaplan MH, Gupta S, Tepper RS.

Pediatr Pulmonol. 2016 May;51(5):478-83. doi: 10.1002/ppul.23327. Epub 2015 Oct 28.

PMID:
26509459
34.

Engineering a therapeutic lectin by uncoupling mitogenicity from antiviral activity.

Swanson MD, Boudreaux DM, Salmon L, Chugh J, Winter HC, Meagher JL, André S, Murphy PV, Oscarson S, Roy R, King S, Kaplan MH, Goldstein IJ, Tarbet EB, Hurst BL, Smee DF, de la Fuente C, Hoffmann HH, Xue Y, Rice CM, Schols D, Garcia JV, Stuckey JA, Gabius HJ, Al-Hashimi HM, Markovitz DM.

Cell. 2015 Oct 22;163(3):746-58. doi: 10.1016/j.cell.2015.09.056. Epub 2015 Oct 22.

35.

STAT4 deficiency reduces the development of atherosclerosis in mice.

Taghavie-Moghadam PL, Gjurich BN, Jabeen R, Krishnamurthy P, Kaplan MH, Dobrian AD, Nadler JL, Galkina EV.

Atherosclerosis. 2015 Nov;243(1):169-78. doi: 10.1016/j.atherosclerosis.2015.08.045. Epub 2015 Sep 4.

36.

PU.1 Expression in T Follicular Helper Cells Limits CD40L-Dependent Germinal Center B Cell Development.

Awe O, Hufford MM, Wu H, Pham D, Chang HC, Jabeen R, Dent AL, Kaplan MH.

J Immunol. 2015 Oct 15;195(8):3705-15. doi: 10.4049/jimmunol.1500780. Epub 2015 Sep 11.

37.

Integrated Transcriptomics Establish Macrophage Polarization Signatures and have Potential Applications for Clinical Health and Disease.

Becker M, De Bastiani MA, Parisi MM, Guma FT, Markoski MM, Castro MA, Kaplan MH, Barbé-Tuana FM, Klamt F.

Sci Rep. 2015 Aug 25;5:13351. doi: 10.1038/srep13351.

38.

STAT3 promotes CD1d-mediated lipid antigen presentation by regulating a critical gene in glycosphingolipid biosynthesis.

Iyer AK, Liu J, Gallo RM, Kaplan MH, Brutkiewicz RR.

Immunology. 2015 Nov;146(3):444-55. doi: 10.1111/imm.12521. Epub 2015 Sep 21.

39.

Poly-ADP-ribosyl polymerase-14 promotes T helper 17 and follicular T helper development.

Mehrotra P, Krishnamurthy P, Sun J, Goenka S, Kaplan MH.

Immunology. 2015 Dec;146(4):537-46. doi: 10.1111/imm.12515. Epub 2015 Sep 28.

40.

An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells.

Wu H, Xu LL, Teuscher P, Liu H, Kaplan MH, Dent AL.

J Immunol. 2015 Sep 1;195(5):2080-9. doi: 10.4049/jimmunol.1500335. Epub 2015 Jul 17.

41.

Altered STAT4 Isoform Expression in Patients with Inflammatory Bowel Disease.

Jabeen R, Miller L, Yao W, Gupta S, Steiner S, Kaplan MH.

Inflamm Bowel Dis. 2015 Oct;21(10):2383-92. doi: 10.1097/MIB.0000000000000495.

42.

Diverse inflammatory cytokines induce selectin ligand expression on murine CD4 T cells via p38α MAPK.

Ebel ME, Awe O, Kaplan MH, Kansas GS.

J Immunol. 2015 Jun 15;194(12):5781-8. doi: 10.4049/jimmunol.1500485. Epub 2015 May 4.

43.

Human Endogenous Retrovirus Type K (HERV-K) Particles Package and Transmit HERV-K-Related Sequences.

Contreras-Galindo R, Kaplan MH, Dube D, Gonzalez-Hernandez MJ, Chan S, Meng F, Dai M, Omenn GS, Gitlin SD, Markovitz DM.

J Virol. 2015 Jul;89(14):7187-201. doi: 10.1128/JVI.00544-15. Epub 2015 Apr 29.

44.

Expansion of a novel endogenous retrovirus throughout the pericentromeres of modern humans.

Zahn J, Kaplan MH, Fischer S, Dai M, Meng F, Saha AK, Cervantes P, Chan SM, Dube D, Omenn GS, Markovitz DM, Contreras-Galindo R.

Genome Biol. 2015 Apr 12;16:74. doi: 10.1186/s13059-015-0641-1.

45.

The development and in vivo function of T helper 9 cells.

Kaplan MH, Hufford MM, Olson MR.

Nat Rev Immunol. 2015 May;15(5):295-307. doi: 10.1038/nri3824. Epub 2015 Apr 7. Review.

46.

The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells.

Richard AC, Tan C, Hawley ET, Gomez-Rodriguez J, Goswami R, Yang XP, Cruz AC, Penumetcha P, Hayes ET, Pelletier M, Gabay O, Walsh M, Ferdinand JR, Keane-Myers A, Choi Y, O'Shea JJ, Al-Shamkhani A, Kaplan MH, Gery I, Siegel RM, Meylan F.

J Immunol. 2015 Apr 15;194(8):3567-82. doi: 10.4049/jimmunol.1401220. Epub 2015 Mar 18. Erratum in: J Immunol. 2015 Dec 15;195(12):5839-40.

47.

CD4 T Cells but Not Th17 Cells Are Required for Mouse Lung Transplant Obliterative Bronchiolitis.

Wu Q, Gupta PK, Suzuki H, Wagner SR, Zhang C, W Cummings O, Fan L, Kaplan MH, Wilkes DS, Shilling RA.

Am J Transplant. 2015 Jul;15(7):1793-1804. doi: 10.1111/ajt.13215. Epub 2015 Mar 13.

48.

TH9 cells are required for tissue mast cell accumulation during allergic inflammation.

Sehra S, Yao W, Nguyen ET, Glosson-Byers NL, Akhtar N, Zhou B, Kaplan MH.

J Allergy Clin Immunol. 2015 Aug;136(2):433-40.e1. doi: 10.1016/j.jaci.2015.01.021. Epub 2015 Mar 5.

49.

Serum MicroRNA-21 as a Biomarker for Allergic Inflammatory Disease in Children.

Sawant DV, Yao W, Wright Z, Sawyers C, Tepper RS, Gupta SK, Kaplan MH, Dent AL.

Microrna. 2015;4(1):36-40.

PMID:
25707810
50.

STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation.

Sheng W, Yang F, Zhou Y, Yang H, Low PY, Kemeny DM, Tan P, Moh A, Kaplan MH, Zhang Y, Fu XY.

Cell Res. 2014 Dec;24(12):1387-402. doi: 10.1038/cr.2014.154. Epub 2014 Nov 21.

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