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Items: 1 to 50 of 417

1.

Exposure: S. aureus skin colonization predisposes to food allergy in the LEAP and LEAP-On studies.

Cook-Mills JM, Kaplan MH, Turner MJ, Kloepfer KM, Kumar R.

J Allergy Clin Immunol. 2019 Jun 27. pii: S0091-6749(19)30825-5. doi: 10.1016/j.jaci.2019.06.014. [Epub ahead of print] No abstract available.

PMID:
31255642
2.

PD-1hi CD8+ resident memory T cells balance immunity and fibrotic sequelae.

Wang Z, Wang S, Goplen NP, Li C, Cheon IS, Dai Q, Huang S, Shan J, Ma C, Ye Z, Xiang M, Limper AH, Porquera EC, Kohlmeier JE, Kaplan MH, Zhang N, Johnson AJ, Vassallo R, Sun J.

Sci Immunol. 2019 Jun 14;4(36). pii: eaaw1217. doi: 10.1126/sciimmunol.aaw1217.

PMID:
31201259
3.

Covalent Heterobivalent Inhibitor Design for Inhibition of IgE-Dependent Penicillin Allergy in a Murine Model.

Deak PE, Kim B, Koh B, Qayum AA, Kiziltepe T, Kaplan MH, Bilgicer B.

J Immunol. 2019 Jul 1;203(1):21-30. doi: 10.4049/jimmunol.1900225. Epub 2019 May 17.

PMID:
31101666
4.

Structural variation of centromeric endogenous retroviruses in human populations and their impact on cutaneous T-cell lymphoma, Sézary syndrome, and HIV infection.

Kaplan MH, Kaminski M, Estes JM, Gitlin SD, Zahn J, Elder JT, Tejasvi T, Gensterblum E, Sawalha AH, McGowan JP, Dosik MH, Direskeneli H, Direskeneli GS, Adebamowo SN, Adebamowo CA, Sajadi M, Contreras-Galindo R.

BMC Med Genomics. 2019 May 2;12(1):58. doi: 10.1186/s12920-019-0505-8.

5.

Designer covalent heterobivalent inhibitors prevent IgE-dependent responses to peanut allergen.

Deak PE, Kim B, Abdul Qayum A, Shin J, Vitalpur G, Kloepfer KM, Turner MJ, Smith N, Shreffler WG, Kiziltepe T, Kaplan MH, Bilgicer B.

Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8966-8974. doi: 10.1073/pnas.1820417116. Epub 2019 Apr 8.

PMID:
30962381
6.

PPAR-γ in Macrophages Limits Pulmonary Inflammation and Promotes Host Recovery following Respiratory Viral Infection.

Huang S, Zhu B, Cheon IS, Goplen NP, Jiang L, Zhang R, Peebles RS, Mack M, Kaplan MH, Limper AH, Sun J.

J Virol. 2019 Apr 17;93(9). pii: e00030-19. doi: 10.1128/JVI.00030-19. Print 2019 May 1.

PMID:
30787149
7.

Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation.

Garg G, Muschaweckh A, Moreno H, Vasanthakumar A, Floess S, Lepennetier G, Oellinger R, Zhan Y, Regen T, Hiltensperger M, Peter C, Aly L, Knier B, Palam LR, Kapur R, Kaplan MH, Waisman A, Rad R, Schotta G, Huehn J, Kallies A, Korn T.

Cell Rep. 2019 Feb 12;26(7):1854-1868.e5. doi: 10.1016/j.celrep.2019.01.070.

8.

Endonuclease and redox activities of human apurinic/apyrimidinic endonuclease 1 have distinctive and essential functions in IgA class switch recombination.

Frossi B, Antoniali G, Yu K, Akhtar N, Kaplan MH, Kelley MR, Tell G, Pucillo CEM.

J Biol Chem. 2019 Mar 29;294(13):5198-5207. doi: 10.1074/jbc.RA118.006601. Epub 2019 Jan 31.

PMID:
30705092
9.

PU.1 controls fibroblast polarization and tissue fibrosis.

Wohlfahrt T, Rauber S, Uebe S, Luber M, Soare A, Ekici A, Weber S, Matei AE, Chen CW, Maier C, Karouzakis E, Kiener HP, Pachera E, Dees C, Beyer C, Daniel C, Gelse K, Kremer AE, Naschberger E, Stürzl M, Butter F, Sticherling M, Finotto S, Kreuter A, Kaplan MH, Jüngel A, Gay S, Nutt SL, Boykin DW, Poon GMK, Distler O, Schett G, Distler JHW, Ramming A.

Nature. 2019 Feb;566(7744):344-349. doi: 10.1038/s41586-019-0896-x. Epub 2019 Jan 30.

PMID:
30700907
10.

Opening the Black Box of Immunosuppression.

Kaplan MH.

J Immunol. 2018 Dec 1;201(11):3147-3148. doi: 10.4049/jimmunol.1801320. No abstract available.

PMID:
30455369
11.

A conserved enhancer regulates Il9 expression in multiple lineages.

Koh B, Abdul Qayum A, Srivastava R, Fu Y, Ulrich BJ, Janga SC, Kaplan MH.

Nat Commun. 2018 Nov 15;9(1):4803. doi: 10.1038/s41467-018-07202-0.

12.

TH9 immunodeficiency in patients with hyper-IgE syndrome.

Olson MR, Kaplan MH.

J Allergy Clin Immunol. 2019 Mar;143(3):935-936. doi: 10.1016/j.jaci.2018.10.044. Epub 2018 Nov 12. No abstract available.

PMID:
30439405
13.

STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells.

Li Y, Liu W, Guan X, Truscott J, Creemers JW, Chen HL, Pesu M, El Abiad RG, Karacay B, Urban JF Jr, Elliott DE, Kaplan MH, Blazar BR, Ince MN.

J Immunol. 2018 Nov 1;201(9):2612-2623. doi: 10.4049/jimmunol.1700808. Epub 2018 Sep 28.

PMID:
30266770
14.

RARα supports the development of Langerhans cells and langerin-expressing conventional dendritic cells.

Hashimoto-Hill S, Friesen L, Park S, Im S, Kaplan MH, Kim CH.

Nat Commun. 2018 Sep 25;9(1):3896. doi: 10.1038/s41467-018-06341-8.

15.

STAT4 is required for the generation of Th1 and Th2, but not Th17 immune responses during monophosphoryl lipid A adjuvant activity.

Varikuti S, Oghumu S, Natarajan G, Kimble J, Sperling RH, Moretti E, Kaplan MH, Satoskar AR.

Int Immunol. 2018 Jul 24;30(8):385. doi: 10.1093/intimm/dxy037. No abstract available.

16.

Effector T Helper Cell Subsets in Inflammatory Bowel Diseases.

Imam T, Park S, Kaplan MH, Olson MR.

Front Immunol. 2018 Jun 1;9:1212. doi: 10.3389/fimmu.2018.01212. eCollection 2018. Review.

17.

Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms.

Ocana JA, Romer E, Sahu R, Pawelzik SC, FitzGerald GA, Kaplan MH, Travers JB.

J Immunol. 2018 Jun 15;200(12):4004-4011. doi: 10.4049/jimmunol.1701145. Epub 2018 Apr 25.

18.

IRF4 Modulates CD8+ T Cell Sensitivity to IL-2 Family Cytokines.

Huang S, Shen Y, Pham D, Jiang L, Wang Z, Kaplan MH, Zhang G, Sun J.

Immunohorizons. 2017 Aug 1;1(6):92-100. doi: 10.4049/immunohorizons.1700020. Epub 2017 Aug 14.

19.

Mechanism for initiation of food allergy: Dependence on skin barrier mutations and environmental allergen costimulation.

Walker MT, Green JE, Ferrie RP, Queener AM, Kaplan MH, Cook-Mills JM.

J Allergy Clin Immunol. 2018 May;141(5):1711-1725.e9. doi: 10.1016/j.jaci.2018.02.003. Epub 2018 Feb 15. Erratum in: J Allergy Clin Immunol. 2018 Jul;142(1):339.

20.

Phenotyping acute and chronic atopic dermatitis-like lesions in Stat6VT mice identifies a role for IL-33 in disease pathogenesis.

DaSilva-Arnold SC, Thyagarajan A, Seymour LJ, Yi Q, Bradish JR, Al-Hassani M, Zhou H, Perdue NJ, Nemeth V, Krbanjevic A, Serezani APM, Olson MR, Spandau DF, Travers JB, Kaplan MH, Turner MJ.

Arch Dermatol Res. 2018 Apr;310(3):197-207. doi: 10.1007/s00403-018-1807-y. Epub 2018 Jan 24.

21.

Neonatal hyperoxia promotes asthma-like features through IL-33-dependent ILC2 responses.

Cheon IS, Son YM, Jiang L, Goplen NP, Kaplan MH, Limper AH, Kita H, Paczesny S, Prakash YS, Tepper R, Ahlfeld SK, Sun J.

J Allergy Clin Immunol. 2018 Oct;142(4):1100-1112. doi: 10.1016/j.jaci.2017.11.025. Epub 2017 Dec 15.

PMID:
29253513
22.

Rapid molecular assays to study human centromere genomics.

Contreras-Galindo R, Fischer S, Saha AK, Lundy JD, Cervantes PW, Mourad M, Wang C, Qian B, Dai M, Meng F, Chinnaiyan A, Omenn GS, Kaplan MH, Markovitz DM.

Genome Res. 2017 Dec;27(12):2040-2049. doi: 10.1101/gr.219709.116. Epub 2017 Nov 15.

23.

STAT4 Regulates the CD8+ Regulatory T Cell/T Follicular Helper Cell Axis and Promotes Atherogenesis in Insulin-Resistant Ldlr-/- Mice.

Taghavie-Moghadam PL, Waseem TC, Hattler J, Glenn LM, Dobrian AD, Kaplan MH, Yang Y, Nurieva R, Nadler JL, Galkina EV.

J Immunol. 2017 Nov 15;199(10):3453-3465. doi: 10.4049/jimmunol.1601429. Epub 2017 Oct 20.

24.

Specifically differentiated T cell subset promotes tumor immunity over fatal immunity.

Ramadan A, Griesenauer B, Adom D, Kapur R, Hanenberg H, Liu C, Kaplan MH, Paczesny S.

J Exp Med. 2017 Dec 4;214(12):3577-3596. doi: 10.1084/jem.20170041. Epub 2017 Oct 16.

25.

Susceptibility of Human Endogenous Retrovirus Type K to Reverse Transcriptase Inhibitors.

Contreras-Galindo R, Dube D, Fujinaga K, Kaplan MH, Markovitz DM.

J Virol. 2017 Nov 14;91(23). pii: e01309-17. doi: 10.1128/JVI.01309-17. Print 2017 Dec 1.

26.

A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function.

Kälin S, Becker M, Ott VB, Serr I, Hosp F, Mollah MMH, Keipert S, Lamp D, Rohner-Jeanrenaud F, Flynn VK, Scherm MG, Nascimento LFR, Gerlach K, Popp V, Dietzen S, Bopp T, Krishnamurthy P, Kaplan MH, Serrano M, Woods SC, Tripal P, Palmisano R, Jastroch M, Blüher M, Wolfrum C, Weigmann B, Ziegler AG, Mann M, Tschöp MH, Daniel C.

Cell Metab. 2017 Sep 5;26(3):475-492.e7. doi: 10.1016/j.cmet.2017.08.008.

27.

Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells.

Rauber S, Luber M, Weber S, Maul L, Soare A, Wohlfahrt T, Lin NY, Dietel K, Bozec A, Herrmann M, Kaplan MH, Weigmann B, Zaiss MM, Fearon U, Veale DJ, Cañete JD, Distler O, Rivellese F, Pitzalis C, Neurath MF, McKenzie ANJ, Wirtz S, Schett G, Distler JHW, Ramming A.

Nat Med. 2017 Aug;23(8):938-944. doi: 10.1038/nm.4373. Epub 2017 Jul 17.

28.

Poly-ADP ribose polymerase-14 limits severity of allergic skin disease.

Krishnamurthy P, Da-Silva-Arnold S, Turner MJ, Travers JB, Kaplan MH.

Immunology. 2017 Nov;152(3):451-461. doi: 10.1111/imm.12782. Epub 2017 Jul 27.

29.

Bcl6 promotes follicular helper T-cell differentiation and PD-1 expression in a Blimp1-independent manner in mice.

Xie MM, Koh BH, Hollister K, Wu H, Sun J, Kaplan MH, Dent AL.

Eur J Immunol. 2017 Jul;47(7):1136-1141. doi: 10.1002/eji.201747034.

30.

Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production.

Olson MR, Ulrich BJ, Hummel SA, Khan I, Meuris B, Cherukuri Y, Dent AL, Janga SC, Kaplan MH.

J Immunol. 2017 Jun 1;198(11):4352-4359. doi: 10.4049/jimmunol.1601792. Epub 2017 May 3.

31.

Key Role of STAT4 Deficiency in the Hematopoietic Compartment in Insulin Resistance and Adipose Tissue Inflammation.

Dobrian AD, Ma K, Glenn LM, Hatcher MA, Haynes BA, Lehrer EJ, Kaplan MH, Nadler JL.

Mediators Inflamm. 2017;2017:5420718. doi: 10.1155/2017/5420718. Epub 2017 Mar 16.

32.

STAT Transcription Factors in T Cell Control of Health and Disease.

Goswami R, Kaplan MH.

Int Rev Cell Mol Biol. 2017;331:123-180. doi: 10.1016/bs.ircmb.2016.09.012. Epub 2016 Nov 9. Review.

PMID:
28325211
33.

Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.

Cheung KL, Zhang F, Jaganathan A, Sharma R, Zhang Q, Konuma T, Shen T, Lee JY, Ren C, Chen CH, Lu G, Olson MR, Zhang W, Kaplan MH, Littman DR, Walsh MJ, Xiong H, Zeng L, Zhou MM.

Mol Cell. 2017 Mar 16;65(6):1068-1080.e5. doi: 10.1016/j.molcel.2016.12.022. Epub 2017 Mar 3.

34.

STAT3 Activation Impairs the Stability of Th9 Cells.

Ulrich BJ, Verdan FF, McKenzie AN, Kaplan MH, Olson MR.

J Immunol. 2017 Mar 15;198(6):2302-2309. doi: 10.4049/jimmunol.1601624. Epub 2017 Jan 30.

35.

Etv5 Regulates IL-10 Production in Th Cells.

Koh B, Hufford MM, Sun X, Kaplan MH.

J Immunol. 2017 Mar 1;198(5):2165-2171. doi: 10.4049/jimmunol.1600801. Epub 2017 Jan 18.

36.

Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors.

Kobayashi M, Nabinger SC, Bai Y, Yoshimoto M, Gao R, Chen S, Yao C, Dong Y, Zhang L, Rodriguez S, Yashiro-Ohtani Y, Pear WS, Carlesso N, Yoder MC, Kapur R, Kaplan MH, Daniel Lacorazza H, Zhang ZY, Liu Y.

Stem Cells. 2017 Apr;35(4):1053-1064. doi: 10.1002/stem.2559. Epub 2017 Jan 19.

37.

Th9 cells in immunity and immunopathological diseases.

Neurath MF, Kaplan MH.

Semin Immunopathol. 2017 Jan;39(1):1-4. doi: 10.1007/s00281-016-0611-z. Epub 2016 Nov 29. Review. No abstract available.

PMID:
27900451
38.

The transcription factor network in Th9 cells.

Kaplan MH.

Semin Immunopathol. 2017 Jan;39(1):11-20. doi: 10.1007/s00281-016-0600-2. Epub 2016 Nov 11. Review.

39.

Increased Th2 activity and diminished skin barrier function cooperate in allergic skin inflammation.

Sehra S, Krishnamurthy P, Koh B, Zhou HM, Seymour L, Akhtar N, Travers JB, Turner MJ, Kaplan MH.

Eur J Immunol. 2016 Nov;46(11):2609-2613. doi: 10.1002/eji.201646421. Epub 2016 Aug 29.

40.

STAT4 is required for the generation of Th1 and Th2, but not Th17 immune responses during monophosphoryl lipid A adjuvant activity.

Varikuti S, Oghumu S, Natarajan G, Kimble J, Sperling RH, Moretti E, Kaplan MH, Satoskar AR.

Int Immunol. 2016 Nov;28(11):565-570. Epub 2016 Aug 30. Erratum in: Int Immunol. 2018 Jul 24;30(8):385.

41.

STAT6 and PARP Family Members in the Development of T Cell-dependent Allergic Inflammation.

Krishnamurthy P, Kaplan MH.

Immune Netw. 2016 Aug;16(4):201-10. doi: 10.4110/in.2016.16.4.201. Epub 2016 Aug 23. Review.

42.

IL-4 impairs wound healing potential in the skin by repressing fibronectin expression.

Serezani APM, Bozdogan G, Sehra S, Walsh D, Krishnamurthy P, Sierra Potchanant EA, Nalepa G, Goenka S, Turner MJ, Spandau DF, Kaplan MH.

J Allergy Clin Immunol. 2017 Jan;139(1):142-151.e5. doi: 10.1016/j.jaci.2016.07.012. Epub 2016 Aug 20.

43.

The ETS Family Transcription Factors Etv5 and PU.1 Function in Parallel To Promote Th9 Cell Development.

Koh B, Hufford MM, Pham D, Olson MR, Wu T, Jabeen R, Sun X, Kaplan MH.

J Immunol. 2016 Sep 15;197(6):2465-72. doi: 10.4049/jimmunol.1502383. Epub 2016 Aug 5.

44.

Mast Cells Regulate Epidermal Barrier Function and the Development of Allergic Skin Inflammation.

Sehra S, Serezani APM, Ocaña JA, Travers JB, Kaplan MH.

J Invest Dermatol. 2016 Jul;136(7):1429-1437. doi: 10.1016/j.jid.2016.03.019. Epub 2016 Mar 25.

45.

STAT3 Impairs STAT5 Activation in the Development of IL-9-Secreting T Cells.

Olson MR, Verdan FF, Hufford MM, Dent AL, Kaplan MH.

J Immunol. 2016 Apr 15;196(8):3297-304. doi: 10.4049/jimmunol.1501801. Epub 2016 Mar 14.

46.

Correction: The TNF-Family Ligand TL1A and Its Receptor DR3 Promote T Cell-Mediated Allergic Immunopathology by Enhancing Differentiation and Pathogenicity of IL-9-Producing T Cells.

Richard AC, Tan C, Hawley ET, Gomez-Rodriguez J, Goswami R, Yang XP, Cruz AC, Penumetcha P, Hayes ET, Pelletier M, Gabay O, Walsh M, Ferdinand JR, Keane-Myers A, Choi Y, O'Shea JJ, Al-Shamkhani A, Kaplan MH, Gery I, Siegel RM, Meylan F.

J Immunol. 2015 Dec 15;195(12):5839-40. doi: 10.4049/jimmunol.1502026. No abstract available.

47.

Increased prevalence of airway reactivity in children with eosinophilic esophagitis.

Krupp NL, Sehra S, Slaven JE, Kaplan MH, Gupta S, Tepper RS.

Pediatr Pulmonol. 2016 May;51(5):478-83. doi: 10.1002/ppul.23327. Epub 2015 Oct 28.

PMID:
26509459
48.

Engineering a therapeutic lectin by uncoupling mitogenicity from antiviral activity.

Swanson MD, Boudreaux DM, Salmon L, Chugh J, Winter HC, Meagher JL, André S, Murphy PV, Oscarson S, Roy R, King S, Kaplan MH, Goldstein IJ, Tarbet EB, Hurst BL, Smee DF, de la Fuente C, Hoffmann HH, Xue Y, Rice CM, Schols D, Garcia JV, Stuckey JA, Gabius HJ, Al-Hashimi HM, Markovitz DM.

Cell. 2015 Oct 22;163(3):746-58. doi: 10.1016/j.cell.2015.09.056. Epub 2015 Oct 22.

49.

STAT4 deficiency reduces the development of atherosclerosis in mice.

Taghavie-Moghadam PL, Gjurich BN, Jabeen R, Krishnamurthy P, Kaplan MH, Dobrian AD, Nadler JL, Galkina EV.

Atherosclerosis. 2015 Nov;243(1):169-78. doi: 10.1016/j.atherosclerosis.2015.08.045. Epub 2015 Sep 4.

50.

PU.1 Expression in T Follicular Helper Cells Limits CD40L-Dependent Germinal Center B Cell Development.

Awe O, Hufford MM, Wu H, Pham D, Chang HC, Jabeen R, Dent AL, Kaplan MH.

J Immunol. 2015 Oct 15;195(8):3705-15. doi: 10.4049/jimmunol.1500780. Epub 2015 Sep 11.

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