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High-resolution and high-accuracy topographic and transcriptional maps of the nucleosome barrier.

Chen Z, Gabizon R, Brown AI, Lee A, Song A, Díaz-Celis C, Kaplan CD, Koslover EF, Yao T, Bustamante C.

Elife. 2019 Jul 31;8. pii: e48281. doi: 10.7554/eLife.48281.


Functional assays for transcription mechanisms in high-throughput.

Qiu C, Kaplan CD.

Methods. 2019 Apr 15;159-160:115-123. doi: 10.1016/j.ymeth.2019.02.017. Epub 2019 Feb 20. Review.


Perturbations of Transcription and Gene Expression-Associated Processes Alter Distribution of Cell Size Values in Saccharomyces cerevisiae.

Maitra N, Anandhakumar J, Blank HM, Kaplan CD, Polymenis M.

G3 (Bethesda). 2019 Jan 9;9(1):239-250. doi: 10.1534/g3.118.200854.


Ambivalence: A Key to Clinical Trial Participation?

Chilton JA, Rasmus ML, Lytton J, Kaplan CD, Jones LA, Hurd TC.

Front Oncol. 2018 Aug 10;8:300. doi: 10.3389/fonc.2018.00300. eCollection 2018. Review.


Correction: High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.

Qiu C, Erinne OC, Dave JM, Cui P, Jin H, Muthukrishnan N, Tang LK, Ganesh Babu S, Lam KC, Vandeventer PJ, Strohner R, Van den Brulle J, Sze SH, Kaplan CD.

PLoS Genet. 2018 Jan 3;14(1):e1007158. doi: 10.1371/journal.pgen.1007158. eCollection 2018 Jan.


Stages of Change Model has Limited Value in Explaining the Change in Use of Cannabis among Adolescent Participants in an Efficacious Motivational Interviewing Intervention.

Dupont HB, Candel MJJM, Lemmens P, Kaplan CD, van de Mheen D, De Vries NK.

J Psychoactive Drugs. 2017 Nov-Dec;49(5):363-372. doi: 10.1080/02791072.2017.1325030. Epub 2017 May 26.


Building trust and diversity in patient-centered oncology clinical trials: An integrated model.

Hurd TC, Kaplan CD, Cook ED, Chilton JA, Lytton JS, Hawk ET, Jones LA.

Clin Trials. 2017 Apr;14(2):170-179. doi: 10.1177/1740774516688860. Epub 2017 Feb 7. Review.


Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo.

Malik I, Qiu C, Snavely T, Kaplan CD.

Nucleic Acids Res. 2017 May 5;45(8):4431-4451. doi: 10.1093/nar/gkx037.


High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.

Qiu C, Erinne OC, Dave JM, Cui P, Jin H, Muthukrishnan N, Tang LK, Babu SG, Lam KC, Vandeventer PJ, Strohner R, Van den Brulle J, Sze SH, Kaplan CD.

PLoS Genet. 2016 Nov 29;12(11):e1006321. doi: 10.1371/journal.pgen.1006321. eCollection 2016 Nov. Erratum in: PLoS Genet. 2018 Jan 3;14 (1):e1007158.


Pairs of promoter pairs in a web of transcription.

Kaplan CD.

Nat Genet. 2016 Aug 30;48(9):975-6. doi: 10.1038/ng.3649.


The mechanism of RNA 5′ capping with NAD+, NADH and desphospho-CoA.

Bird JG, Zhang Y, Tian Y, Panova N, Barvík I, Greene L, Liu M, Buckley B, Krásný L, Lee JK, Kaplan CD, Ebright RH, Nickels BE.

Nature. 2016 Jul 21;535(7612):444-7. Epub 2016 Jul 6.


Relationships Between RNA Polymerase II Activity and Spt Elongation Factors to Spt- Phenotype and Growth in Saccharomyces cerevisiae.

Cui P, Jin H, Vutukuru MR, Kaplan CD.

G3 (Bethesda). 2016 Aug 9;6(8):2489-504. doi: 10.1534/g3.116.030346.


RNA Polymerase II Trigger Loop Mobility: INDIRECT EFFECTS OF Rpb9.

Kaster BC, Knippa KC, Kaplan CD, Peterson DO.

J Biol Chem. 2016 Jul 8;291(28):14883-95. doi: 10.1074/jbc.M116.714394. Epub 2016 May 18.


Assessing the Efficacy of MOTI-4 for Reducing the Use of Cannabis Among Youth in the Netherlands: A Randomized Controlled Trial.

Dupont HB, Candel MJ, Kaplan CD, van de Mheen D, de Vries NK.

J Subst Abuse Treat. 2016 Jun;65:6-12. doi: 10.1016/j.jsat.2015.11.012. Epub 2015 Dec 7.


Towards a Role for Clinical Pathology Diagnostics for Childhood Maltreatment.

Bearer EL, Ji J, Trickett P, Kaplan CD, Mennen F.

Austin J Clin Pathol. 2015;2(2). pii: 1028. Epub 2015 Sep 29.


Mother-Youth Acculturation Gaps and Health-Risking/Emotional Problems among Latin-American Adolescents.

Wiesner M, Arbona C, Capaldi DM, Kim HK, Kaplan CD.

Span J Psychol. 2015 Jul 20;18:E52. doi: 10.1017/sjp.2015.52.


Effectiveness of lifestyle interventions to reduce binge eating symptoms in African American and Hispanic women.

Mama SK, Schembre SM, O'Connor DP, Kaplan CD, Bode S, Lee RE.

Appetite. 2015 Dec;95:269-74. doi: 10.1016/j.appet.2015.07.015. Epub 2015 Jul 16.


Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.

Barnes CO, Calero M, Malik I, Graham BW, Spahr H, Lin G, Cohen AE, Brown IS, Zhang Q, Pullara F, Trakselis MA, Kaplan CD, Calero G.

Mol Cell. 2015 Jul 16;59(2):258-69. doi: 10.1016/j.molcel.2015.06.034.


Uncoupling Promoter Opening from Start-Site Scanning.

Murakami K, Mattei PJ, Davis RE, Jin H, Kaplan CD, Kornberg RD.

Mol Cell. 2015 Jul 2;59(1):133-8. doi: 10.1016/j.molcel.2015.05.021. Epub 2015 Jun 11.


The Histone Chaperones FACT and Spt6 Restrict H2A.Z from Intragenic Locations.

Jeronimo C, Watanabe S, Kaplan CD, Peterson CL, Robert F.

Mol Cell. 2015 Jun 18;58(6):1113-23. doi: 10.1016/j.molcel.2015.03.030. Epub 2015 May 7.


Activation and reactivation of the RNA polymerase II trigger loop for intrinsic RNA cleavage and catalysis.

Čabart P, Jin H, Li L, Kaplan CD.

Transcription. 2014;5(3):e28869. doi: 10.4161/trns.28869.


The application of the rapid assessment and response methodology for cannabis prevention research among youth in the Netherlands.

Dupont HB, Kaplan CD, Braam RV, Verbraeck HT, de Vries NK.

Int J Drug Policy. 2015 Aug;26(8):731-8. doi: 10.1016/j.drugpo.2014.11.003. Epub 2014 Nov 13.


Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms.

Schweikhard V, Meng C, Murakami K, Kaplan CD, Kornberg RD, Block SM.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6642-7. doi: 10.1073/pnas.1405181111. Epub 2014 Apr 14.


RNAs nonspecifically inhibit RNA polymerase II by preventing binding to the DNA template.

Pai DA, Kaplan CD, Kweon HK, Murakami K, Andrews PC, Engelke DR.

RNA. 2014 May;20(5):644-55. doi: 10.1261/rna.040444.113. Epub 2014 Mar 10.


Mechanisms of eukaryotic transcription.

Pufall MA, Kaplan CD.

Genome Biol. 2013;14(9):311.


Divergent contributions of conserved active site residues to transcription by eukaryotic RNA polymerases I and II.

Viktorovskaya OV, Engel KL, French SL, Cui P, Vandeventer PJ, Pavlovic EM, Beyer AL, Kaplan CD, Schneider DA.

Cell Rep. 2013 Sep 12;4(5):974-84. doi: 10.1016/j.celrep.2013.07.044. Epub 2013 Aug 29.


From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II.

Braberg H, Jin H, Moehle EA, Chan YA, Wang S, Shales M, Benschop JJ, Morris JH, Qiu C, Hu F, Tang LK, Fraser JS, Holstege FC, Hieter P, Guthrie C, Kaplan CD, Krogan NJ.

Cell. 2013 Aug 15;154(4):775-88. doi: 10.1016/j.cell.2013.07.033. Epub 2013 Aug 8.


Basic mechanisms of RNA polymerase II activity and alteration of gene expression in Saccharomyces cerevisiae.

Kaplan CD.

Biochim Biophys Acta. 2013 Jan;1829(1):39-54. doi: 10.1016/j.bbagrm.2012.09.007. Epub 2012 Sep 26. Review.


Dissection of Pol II trigger loop function and Pol II activity-dependent control of start site selection in vivo.

Kaplan CD, Jin H, Zhang IL, Belyanin A.

PLoS Genet. 2012;8(4):e1002627. doi: 10.1371/journal.pgen.1002627. Epub 2012 Apr 12.


Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.

Larson MH, Zhou J, Kaplan CD, Palangat M, Kornberg RD, Landick R, Block SM.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6555-60. doi: 10.1073/pnas.1200939109. Epub 2012 Apr 9.


Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation.

Murakami K, Gibbons BJ, Davis RE, Nagai S, Liu X, Robinson PJ, Wu T, Kaplan CD, Kornberg RD.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4816-21. doi: 10.1073/pnas.1201448109. Epub 2012 Mar 12.


Relationship of fruit, vegetable, and fat consumption to binge eating symptoms in African American and Hispanic or Latina women.

Wilson PL, O'Connor DP, Kaplan CD, Bode S, Mama SK, Lee RE.

Eat Behav. 2012 Apr;13(2):179-82. doi: 10.1016/j.eatbeh.2012.01.007. Epub 2012 Jan 24.


Competing for the clamp: promoting RNA polymerase processivity and managing the transition from initiation to elongation.

Hartzog GA, Kaplan CD.

Mol Cell. 2011 Jul 22;43(2):161-3. doi: 10.1016/j.molcel.2011.07.002.


Regulation of cytokine secretion in human CD127(+) LTi-like innate lymphoid cells by Toll-like receptor 2.

Crellin NK, Trifari S, Kaplan CD, Satoh-Takayama N, Di Santo JP, Spits H.

Immunity. 2010 Nov 24;33(5):752-64. doi: 10.1016/j.immuni.2010.10.012. Epub 2010 Nov 4.


Delinquency in context; neighbourhood and gender interactions among adolescents.

Drukker M, Kaplan CD, Feron FJ, Van Os J, Korebrits A.

Epidemiol Psichiatr Soc. 2010 Apr-Jun;19(2):148-58.


A dual interface determines the recognition of RNA polymerase II by RNA capping enzyme.

Suh MH, Meyer PA, Gu M, Ye P, Zhang M, Kaplan CD, Lima CD, Fu J.

J Biol Chem. 2010 Oct 29;285(44):34027-38. doi: 10.1074/jbc.M110.145110. Epub 2010 Aug 18.


The architecture of RNA polymerase fidelity.

Kaplan CD.

BMC Biol. 2010 Jun 22;8:85. doi: 10.1186/1741-7007-8-85.


Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells.

Crellin NK, Trifari S, Kaplan CD, Cupedo T, Spits H.

J Exp Med. 2010 Feb 15;207(2):281-90. doi: 10.1084/jem.20091509. Epub 2010 Feb 8.


Revealing the hidden relationship between nucleosomes and splicing.

Kaplan CD.

Cell Cycle. 2009 Nov 15;8(22):3633-4. No abstract available.


Iron acquisition and transcriptional regulation.

Kaplan CD, Kaplan J.

Chem Rev. 2009 Oct;109(10):4536-52. doi: 10.1021/cr9001676. Review. No abstract available.


Evolution, biogenesis and function of promoter-associated RNAs.

Taft RJ, Kaplan CD, Simons C, Mattick JS.

Cell Cycle. 2009 Aug;8(15):2332-8. Epub 2009 Aug 2.


Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells.

Trifari S, Kaplan CD, Tran EH, Crellin NK, Spits H.

Nat Immunol. 2009 Aug;10(8):864-71. doi: 10.1038/ni.1770. Epub 2009 Jul 5.


A bridge to transcription by RNA polymerase.

Kaplan CD, Kornberg RD.

J Biol. 2008 Dec 2;7(10):39. doi: 10.1186/jbiol99.


The RNA polymerase II trigger loop functions in substrate selection and is directly targeted by alpha-amanitin.

Kaplan CD, Larsson KM, Kornberg RD.

Mol Cell. 2008 Jun 6;30(5):547-56. doi: 10.1016/j.molcel.2008.04.023.


The ibogaine medical subculture.

Alper KR, Lotsof HS, Kaplan CD.

J Ethnopharmacol. 2008 Jan 4;115(1):9-24. Epub 2007 Aug 25.


Polyadenylation site choice in yeast is affected by competition between Npl3 and polyadenylation factor CFI.

Bucheli ME, He X, Kaplan CD, Moore CL, Buratowski S.

RNA. 2007 Oct;13(10):1756-64. Epub 2007 Aug 7.


Aggressive crime, alcohol and drug use, and concentrated poverty in 24 U.S. urban areas.

Valdez A, Kaplan CD, Curtis RL Jr.

Am J Drug Alcohol Abuse. 2007;33(4):595-603.


DNA vaccination against VEGF receptor 2 reduces atherosclerosis in LDL receptor-deficient mice.

Petrovan RJ, Kaplan CD, Reisfeld RA, Curtiss LK.

Arterioscler Thromb Vasc Biol. 2007 May;27(5):1095-100. Epub 2007 Feb 15.


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