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Items: 3

1.

The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification.

Ullius A, Lüscher-Firzlaff J, Costa IG, Walsemann G, Forst AH, Gusmao EG, Kapelle K, Kleine H, Kremmer E, Vervoorts J, Lüscher B.

Nucleic Acids Res. 2014 Jun;42(11):6901-20. doi: 10.1093/nar/gku312. Epub 2014 Apr 29.

2.

The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.

Menssen A, Hydbring P, Kapelle K, Vervoorts J, Diebold J, Lüscher B, Larsson LG, Hermeking H.

Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):E187-96. doi: 10.1073/pnas.1105304109. Epub 2011 Dec 21.

3.

The human trithorax protein hASH2 functions as an oncoprotein.

Lüscher-Firzlaff J, Gawlista I, Vervoorts J, Kapelle K, Braunschweig T, Walsemann G, Rodgarkia-Schamberger C, Schuchlautz H, Dreschers S, Kremmer E, Lilischkis R, Cerni C, Wellmann A, Lüscher B.

Cancer Res. 2008 Feb 1;68(3):749-58. doi: 10.1158/0008-5472.CAN-07-3158.

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