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Association of Bilateral Salpingo-Oophorectomy Before Menopause Onset With Medial Temporal Lobe Neurodegeneration.

Zeydan B, Tosakulwong N, Schwarz CG, Senjem ML, Gunter JL, Reid RI, Gazzuola Rocca L, Lesnick TG, Smith CY, Bailey KR, Lowe VJ, Roberts RO, Jack CR Jr, Petersen RC, Miller VM, Mielke MM, Rocca WA, Kantarci K.

JAMA Neurol. 2018 Oct 15. doi: 10.1001/jamaneurol.2018.3057. [Epub ahead of print]


Personal, reproductive, and familial characteristics associated with bilateral oophorectomy in premenopausal women: A population-based case-control study.

Rocca WA, Gazzuola Rocca L, Smith CY, Grossardt BR, Faubion SS, Shuster LT, Stewart EA, Mielke MM, Kantarci K, Miller VM.

Maturitas. 2018 Nov;117:64-77. doi: 10.1016/j.maturitas.2018.09.002. Epub 2018 Sep 14.


Loss of Ovarian Hormones and Accelerated Somatic and Mental Aging.

Rocca WA, Gazzuola Rocca L, Smith CY, Grossardt BR, Faubion SS, Shuster LT, Kirkland JL, LeBrasseur NK, Schafer MJ, Mielke MM, Kantarci K, Stewart EA, Miller VM.

Physiology (Bethesda). 2018 Nov 1;33(6):374-383. doi: 10.1152/physiol.00024.2018.


Development of a cerebrovascular magnetic resonance imaging biomarker for cognitive aging.

Vemuri P, Lesnick TG, Przybelski SA, Graff-Radford J, Reid RI, Lowe VJ, Zuk SM, Senjem ML, Schwarz CG, Gunter JL, Kantarci K, Machulda MM, Mielke MM, Petersen RC, Knopman DS, Jack CR Jr.

Ann Neurol. 2018 Nov;84(5):705-716. doi: 10.1002/ana.25346. Epub 2018 Oct 25.


Multimodal imaging in RBD - present and future.

Boeve BF, Kantarci K.

Nat Rev Neurol. 2018 Oct;14(10):574-576. doi: 10.1038/s41582-018-0054-3. No abstract available.


Regional cortical perfusion on arterial spin labeling MRI in dementia with Lewy bodies: Associations with clinical severity, glucose metabolism and tau PET.

Nedelska Z, Senjem ML, Przybelski SA, Lesnick TG, Lowe VJ, Boeve BF, Arani A, Vemuri P, Graff-Radford J, Ferman TJ, Jones DT, Savica R, Knopman DS, Petersen RC, Jack CR, Kantarci K.

Neuroimage Clin. 2018 Jun 19;19:939-947. doi: 10.1016/j.nicl.2018.06.020. eCollection 2018.


Understanding the impact of sex and gender in Alzheimer's disease: A call to action.

Nebel RA, Aggarwal NT, Barnes LL, Gallagher A, Goldstein JM, Kantarci K, Mallampalli MP, Mormino EC, Scott L, Yu WH, Maki PM, Mielke MM.

Alzheimers Dement. 2018 Sep;14(9):1171-1183. doi: 10.1016/j.jalz.2018.04.008. Epub 2018 Jun 12.


Elevated medial temporal lobe and pervasive brain tau-PET signal in normal participants.

Lowe VJ, Bruinsma TJ, Min HK, Lundt ES, Fang P, Senjem ML, Boeve BF, Josephs KA, Pandey MK, Murray ME, Kantarci K, Jones DT, Schwarz CG, Knopman DS, Petersen RC, Jack CR Jr.

Alzheimers Dement (Amst). 2018 Feb 7;10:210-216. doi: 10.1016/j.dadm.2018.01.005. eCollection 2018.


White Matter Reference Region in PET Studies of 11C-Pittsburgh Compound B Uptake: Effects of Age and Amyloid-β Deposition.

Lowe VJ, Lundt ES, Senjem ML, Schwarz CG, Min HK, Przybelski SA, Kantarci K, Knopman D, Petersen RC, Jack CR Jr.

J Nucl Med. 2018 Oct;59(10):1583-1589. doi: 10.2967/jnumed.117.204271. Epub 2018 Apr 19.


Brain structure and cognition 3 years after the end of an early menopausal hormone therapy trial.

Kantarci K, Tosakulwong N, Lesnick TG, Zuk SM, Lowe VJ, Fields JA, Gunter JL, Senjem ML, Settell ML, Gleason CE, Shuster LT, Bailey KR, Dowling NM, Asthana S, Jack CR Jr, Rocca WA, Miller VM.

Neurology. 2018 Apr 17;90(16):e1404-e1412. doi: 10.1212/WNL.0000000000005325. Epub 2018 Mar 21.


AutoVOI: real-time automatic prescription of volume-of-interest for single voxel spectroscopy.

Park YW, Deelchand DK, Joers JM, Hanna B, Berrington A, Gillen JS, Kantarci K, Soher BJ, Barker PB, Park H, Öz G, Lenglet C.

Magn Reson Med. 2018 Nov;80(5):1787-1798. doi: 10.1002/mrm.27203. Epub 2018 Apr 6.


Microinfarcts and blood pressure trajectories: response to Dr Niu et al.

Graff-Radford J, Rabinstein AA, Lesnick TG, Reichard RR, Knopman DS, Kantarci K.

J Hum Hypertens. 2018 May;32(5):385. doi: 10.1038/s41371-018-0058-x. Epub 2018 Apr 3. No abstract available.


Clinicopathological and 123I-FP-CIT SPECT correlations in patients with dementia.

Jung Y, Jordan LG 3rd, Lowe VJ, Kantarci K, Parisi JE, Dickson DW, Murray ME, Reichard RR, Ferman TJ, Jones DT, Graff-Radford J, Savica R, Machulda MM, Fields JA, Allen LA, Drubach DA, St Louis EK, Silber MH, Jack CR Jr, Knopman DS, Petersen RC, Boeve BF.

Ann Clin Transl Neurol. 2018 Jan 24;5(3):376-381. doi: 10.1002/acn3.521. eCollection 2018 Mar.


Longitudinal tau PET in ageing and Alzheimer's disease.

Jack CR Jr, Wiste HJ, Schwarz CG, Lowe VJ, Senjem ML, Vemuri P, Weigand SD, Therneau TM, Knopman DS, Gunter JL, Jones DT, Graff-Radford J, Kantarci K, Roberts RO, Mielke MM, Machulda MM, Petersen RC.

Brain. 2018 May 1;141(5):1517-1528. doi: 10.1093/brain/awy059.


Joint associations of β-amyloidosis and cortical thickness with cognition.

Knopman DS, Lundt ES, Therneau TM, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC, Jack CR Jr.

Neurobiol Aging. 2018 May;65:121-131. doi: 10.1016/j.neurobiolaging.2018.01.017. Epub 2018 Feb 2.


In vivo 18F-AV-1451 tau PET signal in MAPT mutation carriers varies by expected tau isoforms.

Jones DT, Knopman DS, Graff-Radford J, Syrjanen JA, Senjem ML, Schwarz CG, Dheel C, Wszolek Z, Rademakers R, Kantarci K, Petersen RC, Jack CR Jr, Lowe VJ, Boeve BF.

Neurology. 2018 Mar 13;90(11):e947-e954. doi: 10.1212/WNL.0000000000005117. Epub 2018 Feb 9.


Cervical spinal cord atrophy: An early marker of progressive MS onset.

Zeydan B, Gu X, Atkinson EJ, Keegan BM, Weinshenker BG, Tillema JM, Pelletier D, Azevedo CJ, Lebrun-Frenay C, Siva A, Okuda DT, Kantarci K, Kantarci OH.

Neurol Neuroimmunol Neuroinflamm. 2018 Jan 22;5(2):e435. doi: 10.1212/NXI.0000000000000435. eCollection 2018 Mar.


Frequency of Acute and Subacute Infarcts in a Population-Based Study.

Arnold Fiebelkorn C, Vemuri P, Rabinstein AA, Mielke MM, Przybelski SA, Kantarci K, Jones DT, Brown RD Jr, Knopman DS, Petersen RC, Jack CR Jr, Graff-Radford J.

Mayo Clin Proc. 2018 Mar;93(3):300-306. doi: 10.1016/j.mayocp.2017.11.021. Epub 2018 Feb 14.


Hormone therapy and urine protein excretion: a multiracial cohort study, systematic review, and meta-analysis.

Kattah AG, Suarez MLG, Milic N, Kantarci K, Zeydan B, Mosley T, Turner ST, Ware EB, Kardia SLR, Garovic VD.

Menopause. 2018 Jun;25(6):625-634. doi: 10.1097/GME.0000000000001062.


Sex differences in cerebrovascular pathologies on FLAIR in cognitively unimpaired elderly.

Fatemi F, Kantarci K, Graff-Radford J, Preboske GM, Weigand SD, Przybelski SA, Knopman DS, Machulda MM, Roberts RO, Mielke MM, Petersen RC, Jack CR Jr, Vemuri P.

Neurology. 2018 Feb 6;90(6):e466-e473. doi: 10.1212/WNL.0000000000004913. Epub 2018 Jan 17.


Widespread brain tau and its association with ageing, Braak stage and Alzheimer's dementia.

Lowe VJ, Wiste HJ, Senjem ML, Weigand SD, Therneau TM, Boeve BF, Josephs KA, Fang P, Pandey MK, Murray ME, Kantarci K, Jones DT, Vemuri P, Graff-Radford J, Schwarz CG, Machulda MM, Mielke MM, Roberts RO, Knopman DS, Petersen RC, Jack CR Jr.

Brain. 2018 Jan 1;141(1):271-287. doi: 10.1093/brain/awx320.


Association Between Microinfarcts and Blood Pressure Trajectories.

Graff-Radford J, Raman MR, Rabinstein AA, Przybelski SA, Lesnick TG, Boeve BF, Murray ME, Dickson DW, Reichard RR, Parisi JE, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K.

JAMA Neurol. 2018 Feb 1;75(2):212-218. doi: 10.1001/jamaneurol.2017.3392.


Cohort profile: the Mayo Clinic Cohort Study of Oophorectomy and Aging-2 (MOA-2) in Olmsted County, Minnesota (USA).

Rocca WA, Gazzuola Rocca L, Smith CY, Grossardt BR, Faubion SS, Shuster LT, Stewart EA, Mielke MM, Kantarci K, Miller VM.

BMJ Open. 2017 Nov 20;7(11):e018861. doi: 10.1136/bmjopen-2017-018861.


Tau, amyloid, and cascading network failure across the Alzheimer's disease spectrum.

Jones DT, Graff-Radford J, Lowe VJ, Wiste HJ, Gunter JL, Senjem ML, Botha H, Kantarci K, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr.

Cortex. 2017 Dec;97:143-159. doi: 10.1016/j.cortex.2017.09.018. Epub 2017 Oct 3.


The limbic and neocortical contribution of α-synuclein, tau, and amyloid β to disease duration in dementia with Lewy bodies.

Ferman TJ, Aoki N, Crook JE, Murray ME, Graff-Radford NR, van Gerpen JA, Uitti RJ, Wszolek ZK, Graff-Radford J, Pedraza O, Kantarci K, Boeve BF, Dickson DW.

Alzheimers Dement. 2018 Mar;14(3):330-339. doi: 10.1016/j.jalz.2017.09.014. Epub 2017 Oct 31.


Prevalence and Natural History of Superficial Siderosis: A Population-Based Study.

Pichler M, Vemuri P, Rabinstein AA, Aakre J, Flemming KD, Brown RD Jr, Kumar N, Kantarci K, Kremers W, Mielke MM, Knopman DS, Jack CR Jr, Petersen RC, Lowe V, Graff-Radford J.

Stroke. 2017 Dec;48(12):3210-3214. doi: 10.1161/STROKEAHA.117.018974. Epub 2017 Oct 25.


Multiple-dose ponezumab for mild-to-moderate Alzheimer's disease: Safety and efficacy.

Landen JW, Cohen S, Billing CB Jr, Cronenberger C, Styren S, Burstein AH, Sattler C, Lee JH, Jack CR Jr, Kantarci K, Schwartz PF, Duggan WT, Zhao Q, Sprenger K, Bednar MM, Binneman B.

Alzheimers Dement (N Y). 2017 May 10;3(3):339-347. doi: 10.1016/j.trci.2017.04.003. eCollection 2017 Sep.


Neuroimaging Correlates of Cerebral Microbleeds: The ARIC Study (Atherosclerosis Risk in Communities).

Graff-Radford J, Simino J, Kantarci K, Mosley TH Jr, Griswold ME, Windham BG, Sharrett AR, Albert MS, Gottesman RF, Jack CR Jr, Vemuri P, Knopman DS.

Stroke. 2017 Nov;48(11):2964-2972. doi: 10.1161/STROKEAHA.117.018336. Epub 2017 Oct 10.


Uptake of AV-1451 in meningiomas.

Bruinsma TJ, Johnson DR, Fang P, Senjem M, Josephs KA, Whitwell JL, Boeve BF, Pandey MK, Kantarci K, Jones DT, Vemuri P, Murray M, Graff-Radford J, Schwarz CG, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ.

Ann Nucl Med. 2017 Dec;31(10):736-743. doi: 10.1007/s12149-017-1205-0. Epub 2017 Sep 8.


1H-MRS metabolites and rate of β-amyloid accumulation on serial PET in clinically normal adults.

Nedelska Z, Przybelski SA, Lesnick TG, Schwarz CG, Lowe VJ, Machulda MM, Kremers WK, Mielke MM, Roberts RO, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K.

Neurology. 2017 Sep 26;89(13):1391-1399. doi: 10.1212/WNL.0000000000004421. Epub 2017 Aug 25.


Influence of preeclampsia and late-life hypertension on MRI measures of cortical atrophy.

Raman MR, Tosakulwong N, Zuk SM, Senjem ML, White WM, Fields JA, Mielke MM, Lesnick TG, Bailey KR, Jack CR Jr, Miller VM, Garovic VD, Kantarci K.

J Hypertens. 2017 Dec;35(12):2479-2485. doi: 10.1097/HJH.0000000000001492.


Myelopathy in Behçet's disease: The Bagel Sign.

Uygunoglu U, Zeydan B, Ozguler Y, Ugurlu S, Seyahi E, Kocer N, Islak C, Kantarci K, Saip S, Siva A, Kantarci OH.

Ann Neurol. 2017 Aug;82(2):288-298. doi: 10.1002/ana.25004. Epub 2017 Aug 10.


Decreased Glutamate Levels in Patients with Amnestic Mild Cognitive Impairment: An sLASER Proton MR Spectroscopy and PiB-PET Study.

Zeydan B, Deelchand DK, Tosakulwong N, Lesnick TG, Kantarci OH, Machulda MM, Knopman DS, Lowe VJ, Jack CR Jr, Petersen RC, Öz G, Kantarci K.

J Neuroimaging. 2017 Nov;27(6):630-636. doi: 10.1111/jon.12454. Epub 2017 Jun 29.


Improved localization, spectral quality, and repeatability with advanced MRS methodology in the clinical setting.

Deelchand DK, Kantarci K, Öz G.

Magn Reson Med. 2018 Mar;79(3):1241-1250. doi: 10.1002/mrm.26788. Epub 2017 Jun 15.


Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.

McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K.

Neurology. 2017 Jul 4;89(1):88-100. doi: 10.1212/WNL.0000000000004058. Epub 2017 Jun 7. Review.


White-matter integrity on DTI and the pathologic staging of Alzheimer's disease.

Kantarci K, Murray ME, Schwarz CG, Reid RI, Przybelski SA, Lesnick T, Zuk SM, Raman MR, Senjem ML, Gunter JL, Boeve BF, Knopman DS, Parisi JE, Petersen RC, Jack CR Jr, Dickson DW.

Neurobiol Aging. 2017 Aug;56:172-179. doi: 10.1016/j.neurobiolaging.2017.04.024. Epub 2017 May 4.


Midlife and Late-Life Vascular Risk Factors and White Matter Microstructural Integrity: The Atherosclerosis Risk in Communities Neurocognitive Study.

Power MC, Tingle JV, Reid RI, Huang J, Sharrett AR, Coresh J, Griswold M, Kantarci K, Jack CR Jr, Knopman D, Gottesman RF, Mosley TH.

J Am Heart Assoc. 2017 May 18;6(5). pii: e005608. doi: 10.1161/JAHA.117.005608.


Population-Based Prevalence of Cerebral Cavernous Malformations in Older Adults: Mayo Clinic Study of Aging.

Flemming KD, Graff-Radford J, Aakre J, Kantarci K, Lanzino G, Brown RD Jr, Mielke MM, Roberts RO, Kremers W, Knopman DS, Petersen RC, Jack CR Jr.

JAMA Neurol. 2017 Jul 1;74(7):801-805. doi: 10.1001/jamaneurol.2017.0439.


Pittsburgh compound-B PET white matter imaging and cognitive function in late multiple sclerosis.

Zeydan B, Lowe VJ, Schwarz CG, Przybelski SA, Tosakulwong N, Zuk SM, Senjem ML, Gunter JL, Roberts RO, Mielke MM, Benarroch EE, Rodriguez M, Machulda MM, Lesnick TG, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K, Kantarci OH.

Mult Scler. 2018 May;24(6):739-749. doi: 10.1177/1352458517707346. Epub 2017 May 5.


Aortic hemodynamics and white matter hyperintensities in normotensive postmenopausal women.

Barnes JN, Harvey RE, Zuk SM, Lundt ES, Lesnick TG, Gunter JL, Senjem ML, Shuster LT, Miller VM, Jack CR Jr, Joyner MJ, Kantarci K.

J Neurol. 2017 May;264(5):938-945. doi: 10.1007/s00415-017-8476-1. Epub 2017 Apr 7.


Preeclampsia and cognitive impairment later in life.

Fields JA, Garovic VD, Mielke MM, Kantarci K, Jayachandran M, White WM, Butts AM, Graff-Radford J, Lahr BD, Bailey KR, Miller VM.

Am J Obstet Gynecol. 2017 Jul;217(1):74.e1-74.e11. doi: 10.1016/j.ajog.2017.03.008. Epub 2017 Mar 18.


Tau aggregation influences cognition and hippocampal atrophy in the absence of beta-amyloid: a clinico-imaging-pathological study of primary age-related tauopathy (PART).

Josephs KA, Murray ME, Tosakulwong N, Whitwell JL, Knopman DS, Machulda MM, Weigand SD, Boeve BF, Kantarci K, Petrucelli L, Lowe VJ, Jack CR Jr, Petersen RC, Parisi JE, Dickson DW.

Acta Neuropathol. 2017 May;133(5):705-715. doi: 10.1007/s00401-017-1681-2. Epub 2017 Feb 3.


Duration and Pathologic Correlates of Lewy Body Disease.

Graff-Radford J, Aakre J, Savica R, Boeve B, Kremers WK, Ferman TJ, Jones DT, Kantarci K, Knopman DS, Dickson DW, Kukull WA, Petersen RC.

JAMA Neurol. 2017 Mar 1;74(3):310-315. doi: 10.1001/jamaneurol.2016.4926.


Imaging markers of cerebrovascular pathologies: Pathophysiology, clinical presentation, and risk factors.

Raman MR, Kantarci K, Murray ME, Jack CR Jr, Vemuri P.

Alzheimers Dement (Amst). 2016 Dec 18;5:5-14. doi: 10.1016/j.dadm.2016.12.006. eCollection 2016. Review.


A large-scale comparison of cortical thickness and volume methods for measuring Alzheimer's disease severity.

Schwarz CG, Gunter JL, Wiste HJ, Przybelski SA, Weigand SD, Ward CP, Senjem ML, Vemuri P, Murray ME, Dickson DW, Parisi JE, Kantarci K, Weiner MW, Petersen RC, Jack CR Jr; Alzheimer's Disease Neuroimaging Initiative.

Neuroimage Clin. 2016 May 30;11:802-812. doi: 10.1016/j.nicl.2016.05.017. eCollection 2016.


AV-1451 tau and β-amyloid positron emission tomography imaging in dementia with Lewy bodies.

Kantarci K, Lowe VJ, Boeve BF, Senjem ML, Tosakulwong N, Lesnick TG, Spychalla AJ, Gunter JL, Fields JA, Graff-Radford J, Ferman TJ, Jones DT, Murray ME, Knopman DS, Jack CR Jr, Petersen RC.

Ann Neurol. 2017 Jan;81(1):58-67. doi: 10.1002/ana.24825. Epub 2016 Dec 19.


Hippocampal volumes predict risk of dementia with Lewy bodies in mild cognitive impairment.

Kantarci K, Lesnick T, Ferman TJ, Przybelski SA, Boeve BF, Smith GE, Kremers WK, Knopman DS, Jack CR Jr, Petersen RC.

Neurology. 2016 Nov 29;87(22):2317-2323. Epub 2016 Nov 2.


Defining imaging biomarker cut points for brain aging and Alzheimer's disease.

Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Lowe VJ, Knopman DS, Gunter JL, Senjem ML, Jones DT, Kantarci K, Machulda MM, Mielke MM, Roberts RO, Vemuri P, Reyes DA, Petersen RC.

Alzheimers Dement. 2017 Mar;13(3):205-216. doi: 10.1016/j.jalz.2016.08.005. Epub 2016 Sep 30.


Association of Kidney Function Biomarkers with Brain MRI Findings: The BRINK Study.

Vemuri P, Knopman DS, Jack CR Jr, Lundt ES, Weigand SD, Zuk SM, Thostenson KB, Reid RI, Kantarci K, Slinin Y, Lakshminarayan K, Davey CS, Murray A.

J Alzheimers Dis. 2017;55(3):1069-1082.


An investigation of cerebrovascular lesions in dementia with Lewy bodies compared to Alzheimer's disease.

Sarro L, Tosakulwong N, Schwarz CG, Graff-Radford J, Przybelski SA, Lesnick TG, Zuk SM, Reid RI, Raman MR, Boeve BF, Ferman TJ, Knopman DS, Comi G, Filippi M, Murray ME, Parisi JE, Dickson DW, Petersen RC, Jack CR Jr, Kantarci K.

Alzheimers Dement. 2017 Mar;13(3):257-266. doi: 10.1016/j.jalz.2016.07.003. Epub 2016 Aug 10.

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