Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 113

1.

Calcium imaging, MEA recordings, and immunostaining images dataset of neuron-astrocyte networks in culture under the effect of norepinephrine.

Bar El Y, Kanner S, Barzilai A, Hanein Y.

Gigascience. 2019 Feb 1;8(2). doi: 10.1093/gigascience/giy161.

2.

Activity changes in neuron-astrocyte networks in culture under the effect of norepinephrine.

Bar El Y, Kanner S, Barzilai A, Hanein Y.

PLoS One. 2018 Oct 17;13(10):e0203761. doi: 10.1371/journal.pone.0203761. eCollection 2018.

3.

Astrocytes restore connectivity and synchronization in dysfunctional cerebellar networks.

Kanner S, Goldin M, Galron R, Ben Jacob E, Bonifazi P, Barzilai A.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):8025-8030. doi: 10.1073/pnas.1718582115. Epub 2018 Jul 16.

4.

Development of a High-Throughput Flow Cytometry Assay to Monitor Defective Trafficking and Rescue of Long QT2 Mutant hERG Channels.

Kanner SA, Jain A, Colecraft HM.

Front Physiol. 2018 Apr 19;9:397. doi: 10.3389/fphys.2018.00397. eCollection 2018.

5.

Sculpting ion channel functional expression with engineered ubiquitin ligases.

Kanner SA, Morgenstern T, Colecraft HM.

Elife. 2017 Dec 19;6. pii: e29744. doi: 10.7554/eLife.29744.

6.

HIF2α-Targeted RNAi Therapeutic Inhibits Clear Cell Renal Cell Carcinoma.

Wong SC, Cheng W, Hamilton H, Nicholas AL, Wakefield DH, Almeida A, Blokhin AV, Carlson J, Neal ZC, Subbotin V, Zhang G, Hegge J, Bertin S, Trubetskoy VS, Rozema DB, Lewis DL, Kanner SB.

Mol Cancer Ther. 2018 Jan;17(1):140-149. doi: 10.1158/1535-7163.MCT-17-0471. Epub 2017 Oct 27.

7.

RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg.

Wooddell CI, Yuen MF, Chan HL, Gish RG, Locarnini SA, Chavez D, Ferrari C, Given BD, Hamilton J, Kanner SB, Lai CL, Lau JYN, Schluep T, Xu Z, Lanford RE, Lewis DL.

Sci Transl Med. 2017 Sep 27;9(409). pii: eaan0241. doi: 10.1126/scitranslmed.aan0241.

8.

Phosphorylation-specific status of RNAi triggers in pharmacokinetic and biodistribution analyses.

Trubetskoy VS, Griffin JB, Nicholas AL, Nord EM, Xu Z, Peterson RM, Wooddell CI, Rozema DB, Wakefield DH, Lewis DL, Kanner SB.

Nucleic Acids Res. 2017 Feb 17;45(3):1469-1478. doi: 10.1093/nar/gkw828.

9.

Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection.

Iram T, Trudler D, Kain D, Kanner S, Galron R, Vassar R, Barzilai A, Blinder P, Fishelson Z, Frenkel D.

Neurobiol Dis. 2016 Dec;96:84-94. doi: 10.1016/j.nbd.2016.08.001. Epub 2016 Aug 17.

PMID:
27544484
10.

Connecting Malfunctioning Glial Cells and Brain Degenerative Disorders.

Kaminsky N, Bihari O, Kanner S, Barzilai A.

Genomics Proteomics Bioinformatics. 2016 Jun;14(3):155-165. doi: 10.1016/j.gpb.2016.04.003. Epub 2016 May 28. Review.

11.

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits.

Kanner S, Bisio M, Cohen G, Goldin M, Tedesco M, Hanein Y, Ben-Jacob E, Barzilai A, Chiappalone M, Bonifazi P.

J Vis Exp. 2015 Apr 15;(98). doi: 10.3791/52572.

12.

Rapamycin increases neuronal survival, reduces inflammation and astrocyte proliferation after spinal cord injury.

Goldshmit Y, Kanner S, Zacs M, Frisca F, Pinto AR, Currie PD, Pinkas-Kramarski R.

Mol Cell Neurosci. 2015 Sep;68:82-91. doi: 10.1016/j.mcn.2015.04.006. Epub 2015 Apr 30.

PMID:
25936601
13.

Synthesis and Biological Evaluation of Pyrazolo[1,5-a]pyrimidine Compounds as Potent and Selective Pim-1 Inhibitors.

Xu Y, Brenning BG, Kultgen SG, Foulks JM, Clifford A, Lai S, Chan A, Merx S, McCullar MV, Kanner SB, Ho KK.

ACS Med Chem Lett. 2014 Oct 22;6(1):63-7. doi: 10.1021/ml500300c. eCollection 2015 Jan 8.

14.

A small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomas.

Foulks JM, Carpenter KJ, Luo B, Xu Y, Senina A, Nix R, Chan A, Clifford A, Wilkes M, Vollmer D, Brenning B, Merx S, Lai S, McCullar MV, Ho KK, Albertson DJ, Call LT, Bearss JJ, Tripp S, Liu T, Stephens BJ, Mollard A, Warner SL, Bearss DJ, Kanner SB.

Neoplasia. 2014 May;16(5):403-12. doi: 10.1016/j.neo.2014.05.004. Epub 2014 Jun 18.

15.

Discovery of 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide activators of the M2 isoform of pyruvate kinase (PKM2).

Xu Y, Liu XH, Saunders M, Pearce S, Foulks JM, Parnell KM, Clifford A, Nix RN, Bullough J, Hendrickson TF, Wright K, McCullar MV, Kanner SB, Ho KK.

Bioorg Med Chem Lett. 2014 Jan 15;24(2):515-9. doi: 10.1016/j.bmcl.2013.12.028. Epub 2013 Dec 17.

PMID:
24374270
16.

SRChing for the substrates of Src.

Reynolds AB, Kanner SB, Bouton AH, Schaller MD, Weed SA, Flynn DC, Parsons JT.

Oncogene. 2014 Sep 11;33(37):4537-47. doi: 10.1038/onc.2013.416. Epub 2013 Oct 14. Review.

PMID:
24121272
17.

Synthesis and structure-activity relationship of 2-arylamino-4-aryl-pyrimidines as potent PAK1 inhibitors.

Xu Y, Foulks JM, Clifford A, Brenning B, Lai S, Luo B, Parnell KM, Merx S, McCullar MV, Kanner SB, Ho KK.

Bioorg Med Chem Lett. 2013 Jul 15;23(14):4072-5. doi: 10.1016/j.bmcl.2013.05.059. Epub 2013 May 28.

PMID:
23756368
18.

Pharmacologic activation of PKM2 slows lung tumor xenograft growth.

Parnell KM, Foulks JM, Nix RN, Clifford A, Bullough J, Luo B, Senina A, Vollmer D, Liu J, McCarthy V, Xu Y, Saunders M, Liu XH, Pearce S, Wright K, O'Reilly M, McCullar MV, Ho KK, Kanner SB.

Mol Cancer Ther. 2013 Aug;12(8):1453-60. doi: 10.1158/1535-7163.MCT-13-0026. Epub 2013 May 29.

19.

In vitro large-scale experimental and theoretical studies for the realization of bi-directional brain-prostheses.

Bonifazi P, Difato F, Massobrio P, Breschi GL, Pasquale V, Levi T, Goldin M, Bornat Y, Tedesco M, Bisio M, Kanner S, Galron R, Tessadori J, Taverna S, Chiappalone M.

Front Neural Circuits. 2013 Mar 14;7:40. doi: 10.3389/fncir.2013.00040. eCollection 2013.

20.

Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors.

Ho KK, Parnell KM, Yuan Y, Xu Y, Kultgen SG, Hamblin S, Hendrickson TF, Luo B, Foulks JM, McCullar MV, Kanner SB.

Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73. doi: 10.1016/j.bmcl.2012.11.013. Epub 2012 Nov 16.

PMID:
23232060
21.

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.

Byers LA, Diao L, Wang J, Saintigny P, Girard L, Peyton M, Shen L, Fan Y, Giri U, Tumula PK, Nilsson MB, Gudikote J, Tran H, Cardnell RJ, Bearss DJ, Warner SL, Foulks JM, Kanner SB, Gandhi V, Krett N, Rosen ST, Kim ES, Herbst RS, Blumenschein GR, Lee JJ, Lippman SM, Ang KK, Mills GB, Hong WK, Weinstein JN, Wistuba II, Coombes KR, Minna JD, Heymach JV.

Clin Cancer Res. 2013 Jan 1;19(1):279-90. doi: 10.1158/1078-0432.CCR-12-1558. Epub 2012 Oct 22.

22.

The role of the neuro-astro-vascular unit in the etiology of ataxia telangiectasia.

Meshulam L, Galron R, Kanner S, De Pittà M, Bonifazi P, Goldin M, Frenkel D, Ben-Jacob E, Barzilai A.

Front Pharmacol. 2012 Sep 17;3:157. doi: 10.3389/fphar.2012.00157. eCollection 2012.

23.

Epigenetic drug discovery: targeting DNA methyltransferases.

Foulks JM, Parnell KM, Nix RN, Chau S, Swierczek K, Saunders M, Wright K, Hendrickson TF, Ho KK, McCullar MV, Kanner SB.

J Biomol Screen. 2012 Jan;17(1):2-17. doi: 10.1177/1087057111421212. Epub 2011 Sep 30. Review. Erratum in: J Biomol Screen. 2012 Jun;17(5):700.

PMID:
21965114
24.

A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination.

Lee DH, Pan Y, Kanner S, Sung P, Borowiec JA, Chowdhury D.

Nat Struct Mol Biol. 2010 Mar;17(3):365-72. doi: 10.1038/nsmb.1769. Epub 2010 Feb 14.

25.

Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress.

Vassin VM, Anantha RW, Sokolova E, Kanner S, Borowiec JA.

J Cell Sci. 2009 Nov 15;122(Pt 22):4070-80. doi: 10.1242/jcs.053702. Epub 2009 Oct 20.

26.

Design, synthesis, and anti-inflammatory properties of orally active 4-(phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38alpha mitogen-activated protein kinase inhibitors.

Hynes J Jr, Dyckman AJ, Lin S, Wrobleski ST, Wu H, Gillooly KM, Kanner SB, Lonial H, Loo D, McIntyre KW, Pitt S, Shen DR, Shuster DJ, Yang X, Zhang R, Behnia K, Zhang H, Marathe PH, Doweyko AM, Tokarski JS, Sack JS, Pokross M, Kiefer SE, Newitt JA, Barrish JC, Dodd J, Schieven GL, Leftheris K.

J Med Chem. 2008 Jan 10;51(1):4-16. Epub 2007 Dec 12.

PMID:
18072718
27.

Monoclonal antibodies to six-transmembrane epithelial antigen of the prostate-1 inhibit intercellular communication in vitro and growth of human tumor xenografts in vivo.

Challita-Eid PM, Morrison K, Etessami S, An Z, Morrison KJ, Perez-Villar JJ, Raitano AB, Jia XC, Gudas JM, Kanner SB, Jakobovits A.

Cancer Res. 2007 Jun 15;67(12):5798-805.

28.

Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors.

Das J, Furch JA, Liu C, Moquin RV, Lin J, Spergel SH, McIntyre KW, Shuster DJ, O'Day KD, Penhallow B, Hung CY, Doweyko AM, Kamath A, Zhang H, Marathe P, Kanner SB, Lin TA, Dodd JH, Barrish JC, Wityak J.

Bioorg Med Chem Lett. 2006 Jul 15;16(14):3706-12. Epub 2006 May 6.

PMID:
16682193
29.

Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors.

Das J, Liu C, Moquin RV, Lin J, Furch JA, Spergel SH, Doweyko AM, McIntyre KW, Shuster DJ, O'Day KD, Penhallow B, Hung CY, Kanner SB, Lin TA, Dodd JH, Barrish JC, Wityak J.

Bioorg Med Chem Lett. 2006 May 1;16(9):2411-5. Epub 2006 Feb 14. Erratum in: Bioorg Med Chem Lett. 2006 Aug 1;16(15):4148. Doweyko, Arthur M [added].

PMID:
16481166
30.

The discovery of orally active triaminotriazine aniline amides as inhibitors of p38 MAP kinase.

Leftheris K, Ahmed G, Chan R, Dyckman AJ, Hussain Z, Ho K, Hynes J Jr, Letourneau J, Li W, Lin S, Metzger A, Moriarty KJ, Riviello C, Shimshock Y, Wen J, Wityak J, Wrobleski ST, Wu H, Wu J, Desai M, Gillooly KM, Lin TH, Loo D, McIntyre KW, Pitt S, Shen DR, Shuster DJ, Zhang R, Diller D, Doweyko A, Sack J, Baldwin J, Barrish J, Dodd J, Henderson I, Kanner S, Schieven GL, Webb M.

J Med Chem. 2004 Dec 2;47(25):6283-91.

PMID:
15566298
31.

Selective Itk inhibitors block T-cell activation and murine lung inflammation.

Lin TA, McIntyre KW, Das J, Liu C, O'Day KD, Penhallow B, Hung CY, Whitney GS, Shuster DJ, Yang X, Townsend R, Postelnek J, Spergel SH, Lin J, Moquin RV, Furch JA, Kamath AV, Zhang H, Marathe PH, Perez-Villar JJ, Doweyko A, Killar L, Dodd JH, Barrish JC, Wityak J, Kanner SB.

Biochemistry. 2004 Aug 31;43(34):11056-62.

PMID:
15323564
32.

Imidazoquinoxaline Src-family kinase p56Lck inhibitors: SAR, QSAR, and the discovery of (S)-N-(2-chloro-6-methylphenyl)-2-(3-methyl-1-piperazinyl)imidazo- [1,5-a]pyrido[3,2-e]pyrazin-6-amine (BMS-279700) as a potent and orally active inhibitor with excellent in vivo antiinflammatory activity.

Chen P, Doweyko AM, Norris D, Gu HH, Spergel SH, Das J, Moquin RV, Lin J, Wityak J, Iwanowicz EJ, McIntyre KW, Shuster DJ, Behnia K, Chong S, de Fex H, Pang S, Pitt S, Shen DR, Thrall S, Stanley P, Kocy OR, Witmer MR, Kanner SB, Schieven GL, Barrish JC.

J Med Chem. 2004 Aug 26;47(18):4517-29.

PMID:
15317463
33.

Ethical considerations for a child's participation in research.

Kanner S, Langerman S, Grey M.

J Spec Pediatr Nurs. 2004 Jan-Mar;9(1):15-23. Review.

PMID:
15040278
34.

Correlates of depressive symptoms in adolescents with type 1 diabetes.

Whittemore R, Kanner S, Singleton S, Hamrin V, Chiu J, Grey M.

Pediatr Diabetes. 2002 Sep;3(3):135-43.

PMID:
15016153
35.

Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56(Lck).

Wityak J, Das J, Moquin RV, Shen Z, Lin J, Chen P, Doweyko AM, Pitt S, Pang S, Shen DR, Fang Q, de Fex HF, Schieven GL, Kanner SB, Barrish JC.

Bioorg Med Chem Lett. 2003 Nov 17;13(22):4007-10.

PMID:
14592495
36.

Depression in adolescents with diabetes.

Kanner S, Hamrin V, Grey M.

J Child Adolesc Psychiatr Nurs. 2003 Jan-Mar;16(1):15-24. Review.

PMID:
12790304
37.

Altering T-cell activation by targeting the multidomain tyrosine kinase Itk.

Kanner SB, Perez-Villar JJ.

Trends Immunol. 2003 May;24(5):249-53. Review. No abstract available.

PMID:
12738418
38.

Phosphorylation of the linker for activation of T-cells by Itk promotes recruitment of Vav.

Perez-Villar JJ, Whitney GS, Sitnick MT, Dunn RJ, Venkatesan S, O'Day K, Schieven GL, Lin TA, Kanner SB.

Biochemistry. 2002 Aug 27;41(34):10732-40.

PMID:
12186560
39.

Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha).

Perez-Villar JJ, O'Day K, Hewgill DH, Nadler SG, Kanner SB.

Int Immunol. 2001 Oct;13(10):1265-74.

PMID:
11581171
40.

Focal adhesion kinase regulates beta1 integrin-dependent T cell migration through an HEF1 effector pathway.

van Seventer GA, Salmen HJ, Law SF, O'Neill GM, Mullen MM, Franz AM, Kanner SB, Golemis EA, van Seventer JM.

Eur J Immunol. 2001 May;31(5):1417-27.

41.
42.

Characteristics of the learner: children and adolescents.

Grey M, Kanner S, Lacey KO.

Diabetes Educ. 1999 Nov-Dec;25(6 Suppl):25-33. Review.

PMID:
10711082
43.

Care of the child or adolescent with type 1 diabetes.

Grey M, Kanner S.

Nurs Clin North Am. 2000 Mar;35(1):1-13. Review.

PMID:
10673562
44.
45.

CD5 negatively regulates the T-cell antigen receptor signal transduction pathway: involvement of SH2-containing phosphotyrosine phosphatase SHP-1.

Perez-Villar JJ, Whitney GS, Bowen MA, Hewgill DH, Aruffo AA, Kanner SB.

Mol Cell Biol. 1999 Apr;19(4):2903-12.

46.

Integrin signalling defects in T-lymphocytes in systemic lupus erythematosus.

Ng TT, Collins IE, Kanner SB, Humphries MJ, Amft N, Wickremasinghe RG, D'Cruz D, Nye KE, Morrow WJ.

Lupus. 1999;8(1):39-51.

PMID:
10025598
47.

Mitogenic properties of a bispecific single-chain Fv-Ig fusion generated from CD2-specific mAb to distinct epitopes.

Connelly RJ, Hayden MS, Scholler JK, Tsu TT, Dupont B, Ledbetter JA, Kanner SB.

Int Immunol. 1998 Dec;10(12):1863-72.

PMID:
9885907
48.
49.

Interleukin-2 induces beta2-integrin-dependent signal transduction involving the focal adhesion kinase-related protein B (fakB).

Brockdorff J, Kanner SB, Nielsen M, Borregaard N, Geisler C, Svejgaard A, Odum N.

Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6959-64.

50.

Wiskott-Aldrich syndrome/X-linked thrombocytopenia: WASP gene mutations, protein expression, and phenotype.

Zhu Q, Watanabe C, Liu T, Hollenbaugh D, Blaese RM, Kanner SB, Aruffo A, Ochs HD.

Blood. 1997 Oct 1;90(7):2680-9.

PMID:
9326235

Supplemental Content

Loading ...
Support Center