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Items: 46

1.

Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells.

Kannappan R, Mattapally S, Wagle PA, Zhang J.

Am J Physiol Heart Circ Physiol. 2018 Sep 1;315(3):H512-H521. doi: 10.1152/ajpheart.00160.2018. Epub 2018 May 18.

PMID:
29775409
2.

Spheroids of cardiomyocytes derived from human-induced pluripotent stem cells improve recovery from myocardial injury in mice.

Mattapally S, Zhu W, Fast VG, Gao L, Worley C, Kannappan R, Borovjagin AV, Zhang J.

Am J Physiol Heart Circ Physiol. 2018 Aug 1;315(2):H327-H339. doi: 10.1152/ajpheart.00688.2017. Epub 2018 Apr 6.

PMID:
29631371
3.

Oxytocin alters cell fate selection of rat neural progenitor cells in vitro.

Palanisamy A, Kannappan R, Xu Z, Martino A, Friese MB, Boyd JD, Crosby G, Culley DJ.

PLoS One. 2018 Jan 18;13(1):e0191160. doi: 10.1371/journal.pone.0191160. eCollection 2018.

4.

Single-cell analysis of the fate of c-kit-positive bone marrow cells.

Czarna A, Sanada F, Matsuda A, Kim J, Signore S, Pereira JD, Sorrentino A, Kannappan R, Cannatà A, Hosoda T, Rota M, Crea F, Anversa P, Leri A.

NPJ Regen Med. 2017 Oct 16;2:27. doi: 10.1038/s41536-017-0032-1. eCollection 2017.

5.

Large Cardiac Muscle Patches Engineered From Human Induced-Pluripotent Stem Cell-Derived Cardiac Cells Improve Recovery From Myocardial Infarction in Swine.

Gao L, Gregorich ZR, Zhu W, Mattapally S, Oduk Y, Lou X, Kannappan R, Borovjagin AV, Walcott GP, Pollard AE, Fast VG, Hu X, Lloyd SG, Ge Y, Zhang J.

Circulation. 2018 Apr 17;137(16):1712-1730. doi: 10.1161/CIRCULATIONAHA.117.030785. Epub 2017 Dec 12.

PMID:
29233823
6.

VEGF nanoparticles repair the heart after myocardial infarction.

Oduk Y, Zhu W, Kannappan R, Zhao M, Borovjagin AV, Oparil S, Zhang JJ.

Am J Physiol Heart Circ Physiol. 2018 Feb 1;314(2):H278-H284. doi: 10.1152/ajpheart.00471.2017. Epub 2017 Nov 3.

PMID:
29101176
7.

p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo.

Kannappan R, Matsuda A, Ferreira-Martins J, Zhang E, Palano G, Czarna A, Cabral-Da-Silva MC, Bastos-Carvalho A, Sanada F, Ide N, Rota M, Blasco MA, Serrano M, Anversa P, Leri A.

EBioMedicine. 2017 Feb;16:224-237. doi: 10.1016/j.ebiom.2017.01.028. Epub 2017 Jan 31.

8.

Meeting Report for NIH 2016 Progenitor Cell Biology Consortium Cardiovascular Tissue Engineering 2016.

Kannappan R, Zhang J.

Circ Res. 2016 Oct 14;119(9):981-983. No abstract available.

PMID:
27737941
9.

Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors. EVIDENCE FOR THE ROLE OF REACTIVE OXYGEN SPECIES AND JNK.

Prasad S, Yadav VR, Kannappan R, Aggarwal BB.

J Biol Chem. 2016 Aug 5;291(32):16924. doi: 10.1074/jbc.A110.183699. No abstract available.

10.
11.

Reduction in Kv Current Enhances the Temporal Dispersion of the Action Potential in Diabetic Myocytes: Insights From a Novel Repolarization Algorithm.

Meo M, Meste O, Signore S, Sorrentino A, Cannata A, Zhou Y, Matsuda A, Luciani M, Kannappan R, Goichberg P, Leri A, Anversa P, Rota M.

J Am Heart Assoc. 2016 Feb 19;5(2). pii: e003078. doi: 10.1161/JAHA.115.003078.

12.

Retraction notice to "Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake" [Biochem. Pharmacol. 80 (2010) 1021-1032].

Yadav VR, Prasad S, Kannappan R, Ravindran J, Chaturvedi MM, Vaahtera L, Parkkinen J, Aggarwal BB.

Biochem Pharmacol. 2016 Feb 15;102:142. doi: 10.1016/j.bcp.2015.11.007. Epub 2016 Feb 20. No abstract available.

PMID:
29065988
13.

Myocyte repolarization modulates myocardial function in aging dogs.

Sorrentino A, Signore S, Qanud K, Borghetti G, Meo M, Cannata A, Zhou Y, Wybieralska E, Luciani M, Kannappan R, Zhang E, Matsuda A, Webster A, Cimini M, Kertowidjojo E, D'Alessandro DA, Wunimenghe O, Michler RE, Royer C, Goichberg P, Leri A, Barrett EG, Anversa P, Hintze TH, Rota M.

Am J Physiol Heart Circ Physiol. 2016 Apr 1;310(7):H873-90. doi: 10.1152/ajpheart.00682.2015. Epub 2016 Jan 22.

14.

Late Na(+) current and protracted electrical recovery are critical determinants of the aging myopathy.

Signore S, Sorrentino A, Borghetti G, Cannata A, Meo M, Zhou Y, Kannappan R, Pasqualini F, O'Malley H, Sundman M, Tsigkas N, Zhang E, Arranto C, Mangiaracina C, Isobe K, Sena BF, Kim J, Goichberg P, Nahrendorf M, Isom LL, Leri A, Anversa P, Rota M.

Nat Commun. 2015 Nov 6;6:8803. doi: 10.1038/ncomms9803.

15.

Response to letter regarding article, "growth properties of cardiac stem cells are a novel biomarker of patients' outcome after coronary bypass surgery".

D'Amario D, Leone AM, Iaconelli A, Luciani N, Gaudino M, Kannappan R, Manchi M, Severino A, Shin SH, Graziani F, Biasillo G, Macchione A, Smaldone C, Cellini C, Siracusano A, Ottaviani L, Massetti M, Goichberg P, Leri A, Anversa P, Crea F.

Circulation. 2014 Sep 23;130(13):e118-9. doi: 10.1161/CIRCULATIONAHA.114.010924. No abstract available. Erratum in: Circulation. 2015 Dec 1;132(22):e364.

PMID:
25245852
16.

Response to letter regarding article "Inositol 1,4,5-trisphosphate receptors and human left ventricular myocytes".

Signore S, Sorrentino A, Ferreira-Martins J, Kannappan R, Shafaie M, Del Ben F, Isobe K, Arranto C, Wybieralska E, Webster A, Sanada F, Ogórek B, Zheng H, Liu X, del Monte F, D'Alessandro DA, Wunimenghe O, Michler RE, Hosoda T, Goichberg P, Leri A, Kajstura J, Anversa P, Rota M.

Circulation. 2014 May 27;129(21):e510-1. doi: 10.1161/CIRCULATIONAHA.114.009347. No abstract available.

17.

Growth properties of cardiac stem cells are a novel biomarker of patients' outcome after coronary bypass surgery.

D'Amario D, Leone AM, Iaconelli A, Luciani N, Gaudino M, Kannappan R, Manchi M, Severino A, Shin SH, Graziani F, Biasillo G, Macchione A, Smaldone C, De Maria GL, Cellini C, Siracusano A, Ottaviani L, Massetti M, Goichberg P, Leri A, Anversa P, Crea F.

Circulation. 2014 Jan 14;129(2):157-72. doi: 10.1161/CIRCULATIONAHA.113.006591. Epub 2013 Nov 18. Erratum in: Circulation. 2014 Aug 12;130(7):e65. Erratum in: Circulation. 2015 Dec 1;132(22):e363.

18.

Age-associated defects in EphA2 signaling impair the migration of human cardiac progenitor cells.

Goichberg P, Kannappan R, Cimini M, Bai Y, Sanada F, Sorrentino A, Signore S, Kajstura J, Rota M, Anversa P, Leri A.

Circulation. 2013 Nov 12;128(20):2211-23. doi: 10.1161/CIRCULATIONAHA.113.004698. Epub 2013 Oct 18. Erratum in: Circulation. 2015 Jul 28;132(4):e30. Circulation. 2015 Dec 1;132(22):e361.

19.

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

Signore S, Sorrentino A, Ferreira-Martins J, Kannappan R, Shafaie M, Del Ben F, Isobe K, Arranto C, Wybieralska E, Webster A, Sanada F, Ogórek B, Zheng H, Liu X, Del Monte F, D'Alessandro DA, Wunimenghe O, Michler RE, Hosoda T, Goichberg P, Leri A, Kajstura J, Anversa P, Rota M.

Circulation. 2013 Sep 17;128(12):1286-97. doi: 10.1161/CIRCULATIONAHA.113.002764. Epub 2013 Aug 27.

20.

Redox control of molecular motions in bipyridinium appended calixarenes.

Iordache A, Kannappan R, Métay E, Duclos MC, Pellet-Rostaing S, Lemaire M, Milet A, Saint-Aman E, Bucher C.

Org Biomol Chem. 2013 Jul 14;11(26):4383-9. doi: 10.1039/c3ob40356d. Epub 2013 May 22.

PMID:
23695840
21.

Selection of chiral zinc catalysts for the kinetic resolution of esters via dynamic templating.

Kannappan R, Nicholas KM.

ACS Comb Sci. 2013 Feb 11;15(2):90-100. doi: 10.1021/co3001023. Epub 2013 Jan 22.

PMID:
23240865
22.

Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.

Prasad S, Yadav VR, Sung B, Reuter S, Kannappan R, Deorukhkar A, Diagaradjane P, Wei C, Baladandayuthapani V, Krishnan S, Guha S, Aggarwal BB.

Clin Cancer Res. 2012 Sep 15;18(18):4942-53. doi: 10.1158/1078-0432.CCR-11-2805. Epub 2012 Jul 25.

23.
24.

Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer.

Yadav VR, Prasad S, Sung B, Kannappan R, Aggarwal BB.

Toxins (Basel). 2010 Oct;2(10):2428-66. doi: 10.3390/toxins2102428. Epub 2010 Oct 22. Review.

25.

Zyflamend sensitizes tumor cells to TRAIL-induced apoptosis through up-regulation of death receptors and down-regulation of survival proteins: role of ROS-dependent CCAAT/enhancer-binding protein-homologous protein pathway.

Kim JH, Park B, Gupta SC, Kannappan R, Sung B, Aggarwal BB.

Antioxid Redox Signal. 2012 Mar 1;16(5):413-27. doi: 10.1089/ars.2011.3982. Epub 2011 Dec 15. Erratum in: Antioxid Redox Signal. 2013 Jan 10;18(2):219-20.

26.

Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1.

Phromnoi K, Prasad S, Gupta SC, Kannappan R, Reuter S, Limtrakul P, Aggarwal BB.

Mol Pharmacol. 2011 Nov;80(5):889-99. doi: 10.1124/mol.111.073676. Epub 2011 Aug 4.

28.

Role of nuclear factor κB-mediated inflammatory pathways in cancer-related symptoms and their regulation by nutritional agents.

Gupta SC, Kim JH, Kannappan R, Reuter S, Dougherty PM, Aggarwal BB.

Exp Biol Med (Maywood). 2011 Jun 1;236(6):658-71. doi: 10.1258/ebm.2011.011028. Epub 2011 May 12. Review.

29.

Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approach.

Aggarwal BB, Prasad S, Reuter S, Kannappan R, Yadev VR, Park B, Kim JH, Gupta SC, Phromnoi K, Sundaram C, Prasad S, Chaturvedi MM, Sung B.

Curr Drug Targets. 2011 Oct;12(11):1595-653.

30.

Tocotrienols fight cancer by targeting multiple cell signaling pathways.

Kannappan R, Gupta SC, Kim JH, Aggarwal BB.

Genes Nutr. 2012 Jan;7(1):43-52. doi: 10.1007/s12263-011-0220-3. Epub 2011 Apr 9.

31.

Neuroprotection by spice-derived nutraceuticals: you are what you eat!

Kannappan R, Gupta SC, Kim JH, Reuter S, Aggarwal BB.

Mol Neurobiol. 2011 Oct;44(2):142-59. doi: 10.1007/s12035-011-8168-2. Epub 2011 Mar 1. Review.

32.

Chemosensitization of tumors by resveratrol.

Gupta SC, Kannappan R, Reuter S, Kim JH, Aggarwal BB.

Ann N Y Acad Sci. 2011 Jan;1215:150-60. doi: 10.1111/j.1749-6632.2010.05852.x. Review.

33.

NF-κB addiction and its role in cancer: 'one size does not fit all'.

Chaturvedi MM, Sung B, Yadav VR, Kannappan R, Aggarwal BB.

Oncogene. 2011 Apr 7;30(14):1615-30. doi: 10.1038/onc.2010.566. Epub 2010 Dec 20. Review.

35.

Thiocolchicoside exhibits anticancer effects through downregulation of NF-κB pathway and its regulated gene products linked to inflammation and cancer.

Reuter S, Prasad S, Phromnoi K, Ravindran J, Sung B, Yadav VR, Kannappan R, Chaturvedi MM, Aggarwal BB.

Cancer Prev Res (Phila). 2010 Nov;3(11):1462-72. doi: 10.1158/1940-6207.CAPR-10-0037. Epub 2010 Oct 26.

36.

A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents.

Phromnoi K, Reuter S, Sung B, Prasad S, Kannappan R, Yadav VR, Chanmahasathien W, Limtrakul P, Aggarwal BB.

Mol Pharmacol. 2011 Feb;79(2):279-89. doi: 10.1124/mol.110.067512. Epub 2010 Oct 7. Retraction in: Mol Pharmacol. 2016 Jul;90(1):64.

37.

Modification of cysteine 179 of IkappaBalpha kinase by nimbolide leads to down-regulation of NF-kappaB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents.

Gupta SC, Prasad S, Reuter S, Kannappan R, Yadav VR, Ravindran J, Hema PS, Chaturvedi MM, Nair M, Aggarwal BB.

J Biol Chem. 2010 Nov 12;285(46):35406-17. doi: 10.1074/jbc.M110.161984. Epub 2010 Sep 9. Erratum in: J Biol Chem. 2012 Apr 6;287(15):12152.

38.

Embelin suppresses osteoclastogenesis induced by receptor activator of NF-κB ligand and tumor cells in vitro through inhibition of the NF-κB cell signaling pathway.

Reuter S, Prasad S, Phromnoi K, Kannappan R, Yadav VR, Aggarwal BB.

Mol Cancer Res. 2010 Oct;8(10):1425-36. doi: 10.1158/1541-7786.MCR-10-0141. Epub 2010 Sep 8. Retraction in: Mol Cancer Res. 2018 Sep;16(9):1443.

39.

Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor.

Yadav VR, Sung B, Prasad S, Kannappan R, Cho SG, Liu M, Chaturvedi MM, Aggarwal BB.

J Mol Med (Berl). 2010 Dec;88(12):1243-53. doi: 10.1007/s00109-010-0669-3. Epub 2010 Aug 27. Erratum in: J Mol Med (Berl). 2013 Mar;91(3):407-8.

41.

Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic diseases.

Aggarwal BB, Sundaram C, Prasad S, Kannappan R.

Biochem Pharmacol. 2010 Dec 1;80(11):1613-31. doi: 10.1016/j.bcp.2010.07.043. Epub 2010 Aug 7. Review.

42.

Gamma-tocotrienol promotes TRAIL-induced apoptosis through reactive oxygen species/extracellular signal-regulated kinase/p53-mediated upregulation of death receptors.

Kannappan R, Ravindran J, Prasad S, Sung B, Yadav VR, Reuter S, Chaturvedi MM, Aggarwal BB.

Mol Cancer Ther. 2010 Aug;9(8):2196-207. doi: 10.1158/1535-7163.MCT-10-0277. Epub 2010 Aug 3. Retraction in: Mol Cancer Ther. 2018 Sep;17(9):2072.

43.

Delivery of antiinflammatory nutraceuticals by nanoparticles for the prevention and treatment of cancer.

Nair HB, Sung B, Yadav VR, Kannappan R, Chaturvedi MM, Aggarwal BB.

Biochem Pharmacol. 2010 Dec 15;80(12):1833-43. doi: 10.1016/j.bcp.2010.07.021. Epub 2010 Jul 21. Review.

44.

Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake.

Yadav VR, Prasad S, Kannappan R, Ravindran J, Chaturvedi MM, Vaahtera L, Parkkinen J, Aggarwal BB.

Biochem Pharmacol. 2010 Oct 1;80(7):1021-32. doi: 10.1016/j.bcp.2010.06.022. Epub 2010 Jun 23. Retraction in: Biochem Pharmacol. 2016 Feb 15;102:142.

45.
46.

Identification and characterization of cathepsin D in a highly purified sialidase from starfish A. pectinifera.

Kannappan R, Satoh Y, Iriyama N, Ando M, Sawada MT, Takahashi N, Furuhata K, Uda Y.

J Biochem. 2008 Jan;143(1):117-22. Epub 2007 Oct 30.

PMID:
17977858

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