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Items: 1 to 50 of 327

1.

Roles of p53 Family Structure and Function in Non-Canonical Response Element Binding and Activation.

Cai BH, Chao CF, Huang HC, Lee HY, Kannagi R, Chen JY.

Int J Mol Sci. 2019 Jul 27;20(15). pii: E3681. doi: 10.3390/ijms20153681. Review.

2.

Sialyl Glycan Expression on T Cell Subsets in Asthma: a correlation with disease severity and blood parameters.

Yeh YL, Wu WC, Kannagi R, Chiang BL, Liu FT, Lee YL.

Sci Rep. 2019 Jun 20;9(1):8947. doi: 10.1038/s41598-019-45040-2.

3.

Epigenetic silencing of the synthesis of immunosuppressive Siglec ligand glycans by NF-κB/EZH2/YY1 axis in early-stage colon cancers.

Huang HC, Chao CC, Wu PH, Chung HY, Lee HY, Suen CS, Hwang MJ, Cai BH, Kannagi R.

Biochim Biophys Acta Gene Regul Mech. 2019 Feb;1862(2):173-183. doi: 10.1016/j.bbagrm.2019.01.002. Epub 2019 Feb 1.

PMID:
30716533
4.

Synergistic activation of the NEU4 promoter by p73 and AP2 in colon cancer cells.

Cai BH, Wu PH, Chou CK, Huang HC, Chao CC, Chung HY, Lee HY, Chen JY, Kannagi R.

Sci Rep. 2019 Jan 30;9(1):950. doi: 10.1038/s41598-018-37521-7.

5.

BLIMP1 transcriptionally induced by EGFR activation and post-translationally regulated by proteasome and lysosome is involved in keratinocyte differentiation, migration and inflammation.

Chang HC, Huang DY, Wu NL, Kannagi R, Wang LF, Lin WW.

J Dermatol Sci. 2018 Nov;92(2):151-161. doi: 10.1016/j.jdermsci.2018.08.011. Epub 2018 Aug 31.

PMID:
30197274
6.

Distinct substrate specificities of human GlcNAc-6-sulfotransferases revealed by mass spectrometry-based sulfoglycomic analysis.

Yu SY, Hsiao CT, Izawa M, Yusa A, Ishida H, Nakamura S, Yagi H, Kannagi R, Khoo KH.

J Biol Chem. 2018 Sep 28;293(39):15163-15177. doi: 10.1074/jbc.RA118.001937. Epub 2018 Aug 9.

7.

Gangliosides and Tumors.

Kannagi R, Cai BH, Huang HC, Chao CC, Sakuma K.

Methods Mol Biol. 2018;1804:143-171. doi: 10.1007/978-1-4939-8552-4_6. Review.

PMID:
29926407
8.

Inhibition of Endothelial SCUBE2 (Signal Peptide-CUB-EGF Domain-Containing Protein 2), a Novel VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) Coreceptor, Suppresses Tumor Angiogenesis.

Lin YC, Liu CY, Kannagi R, Yang RB.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):1202-1215. doi: 10.1161/ATVBAHA.117.310506. Epub 2018 Mar 15.

PMID:
29545238
9.

Concerted mass spectrometry-based glycomic approach for precision mapping of sulfo sialylated N-glycans on human peripheral blood mononuclear cells and lymphocytes.

Chen JY, Huang HH, Yu SY, Wu SJ, Kannagi R, Khoo KH.

Glycobiology. 2018 Dec 1;28(1):9-20. doi: 10.1093/glycob/cwx091.

PMID:
29087466
10.

FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core fucosylation.

Tu CF, Wu MY, Lin YC, Kannagi R, Yang RB.

Breast Cancer Res. 2017 Oct 5;19(1):111. doi: 10.1186/s13058-017-0904-8.

11.

Glycosylation Changes in Cancer.

Varki A, Kannagi R, Toole B, Stanley P.

In: Varki A, Cummings RD, Esko JD, Stanley P, Hart GW, Aebi M, Darvill AG, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger PH, editors. Essentials of Glycobiology [Internet]. 3rd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2015-2017. Chapter 47.
2017.

12.

Downregulation of miR-199a/b-5p is associated with GCNT2 induction upon epithelial-mesenchymal transition in colon cancer.

Chao CC, Wu PH, Huang HC, Chung HY, Chou YC, Cai BH, Kannagi R.

FEBS Lett. 2017 Jul;591(13):1902-1917. doi: 10.1002/1873-3468.12685. Epub 2017 Jun 10.

13.

Anaplasma marginale Outer Membrane Protein A Is an Adhesin That Recognizes Sialylated and Fucosylated Glycans and Functionally Depends on an Essential Binding Domain.

Hebert KS, Seidman D, Oki AT, Izac J, Emani S, Oliver LD Jr.,, Miller DP, Tegels BK, Kannagi R, Marconi RT, Carlyon JA.

Infect Immun. 2017 Feb 23;85(3). pii: e00968-16. doi: 10.1128/IAI.00968-16. Print 2017 Mar.

14.

Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis.

Lin YC, Chao TY, Yeh CT, Roffler SR, Kannagi R, Yang RB.

Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):144-155. doi: 10.1161/ATVBAHA.116.308546. Epub 2016 Nov 10.

PMID:
27834687
15.

A/T gap tolerance in the core sequence and flanking sequence requirements of non-canonical p53 response elements.

Cai BH, Chao CF, Lin HC, Huang HY, Kannagi R, Chen JY.

J Biochem. 2016 Jun;159(6):563-72. doi: 10.1093/jb/mvw005. Epub 2016 Jan 27.

16.

Spleen Tyrosine Kinase Mediates EGFR Signaling to Regulate Keratinocyte Terminal Differentiation.

Wu NL, Huang DY, Wang LF, Kannagi R, Fan YC, Lin WW.

J Invest Dermatol. 2016 Jan;136(1):192-201. doi: 10.1038/JID.2015.381.

17.

Unmasking of CD22 Co-receptor on Germinal Center B-cells Occurs by Alternative Mechanisms in Mouse and Man.

Macauley MS, Kawasaki N, Peng W, Wang SH, He Y, Arlian BM, McBride R, Kannagi R, Khoo KH, Paulson JC.

J Biol Chem. 2015 Dec 11;290(50):30066-77. doi: 10.1074/jbc.M115.691337. Epub 2015 Oct 27.

18.

Spleen Tyrosine Kinase Mediates EGFR Signaling to Regulate Keratinocyte Terminal Differentiation.

Wu NL, Huang DY, Wang LF, Kannagi R, Fan YC, Lin WW.

J Invest Dermatol. 2015 Sep 30. doi: 10.1038/jid.2015.381. [Epub ahead of print]

PMID:
26422383
19.

Hypoxia remodels the composition of the constituent ceramide species of HexCer and Hex2Cer with phytosphingosine and hydroxy fatty acids in human colon cancer LS174T cells.

Tanaka K, Tamiya-Koizumi K, Yamada M, Murate T, Kannagi R, Kyogashima M.

Glycoconj J. 2015 Nov;32(8):615-23. doi: 10.1007/s10719-015-9607-5. Epub 2015 Jul 22.

PMID:
26194060
20.

Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3high regulatory T cells in humans.

Miyara M, Chader D, Sage E, Sugiyama D, Nishikawa H, Bouvry D, Claër L, Hingorani R, Balderas R, Rohrer J, Warner N, Chapelier A, Valeyre D, Kannagi R, Sakaguchi S, Amoura Z, Gorochov G.

Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7225-30. doi: 10.1073/pnas.1508224112. Epub 2015 May 26.

21.

Major glycan structure underlying expression of the Lewis X epitope in the developing brain is O-mannose-linked glycans on phosphacan/RPTPβ.

Yaji S, Manya H, Nakagawa N, Takematsu H, Endo T, Kannagi R, Yoshihara T, Asano M, Oka S.

Glycobiology. 2015 Apr;25(4):376-85. doi: 10.1093/glycob/cwu118. Epub 2014 Oct 31.

22.

Therapeutic adenoviral gene transfer of a glycosyltransferase for prevention of peritoneal dissemination and metastasis of gastric cancer.

Kawamura YI, Adachi Y, Curiel DT, Kawashima R, Kannagi R, Nishimoto N, Dohi T.

Cancer Gene Ther. 2014 Oct;21(10):427-33. doi: 10.1038/cgt.2014.46. Epub 2014 Sep 12.

PMID:
25213663
23.

Introduction to special issue: 'emerging roles of siglecs in health and disease'.

Crocker PR, Kannagi R.

Glycobiology. 2014 Sep;24(9):784. doi: 10.1093/glycob/cwu073. No abstract available.

PMID:
25080408
24.
25.

KSGal6ST generates galactose-6-O-sulfate in high endothelial venules but does not contribute to L-selectin-dependent lymphocyte homing.

Patnode ML, Yu SY, Cheng CW, Ho MY, Tegesjö L, Sakuma K, Uchimura K, Khoo KH, Kannagi R, Rosen SD.

Glycobiology. 2013 Mar;23(3):381-94. doi: 10.1093/glycob/cws166. Epub 2012 Dec 18.

26.

Sialic acid cyclization of human Th homing receptor glycan associated with recurrent exacerbations of atopic dermatitis.

Sakuma K, Furuhashi T, Kondo S, Yabe U, Ohmori K, Ito H, Aoki M, Morita A, Kannagi R.

J Dermatol Sci. 2012 Dec;68(3):187-93. doi: 10.1016/j.jdermsci.2012.09.015. Epub 2012 Oct 8.

PMID:
23088960
27.

Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial-mesenchymal transition.

Sakuma K, Aoki M, Kannagi R.

Proc Natl Acad Sci U S A. 2012 May 15;109(20):7776-81. doi: 10.1073/pnas.1111135109. Epub 2012 Apr 30.

28.

Colonic epithelial cells express specific ligands for mucosal macrophage immunosuppressive receptors siglec-7 and -9.

Miyazaki K, Sakuma K, Kawamura YI, Izawa M, Ohmori K, Mitsuki M, Yamaji T, Hashimoto Y, Suzuki A, Saito Y, Dohi T, Kannagi R.

J Immunol. 2012 May 1;188(9):4690-700. doi: 10.4049/jimmunol.1100605. Epub 2012 Mar 30.

29.

Role of down-regulated neutral ceramidase during all-trans retinoic acid-induced neuronal differentiation in SH-SY5Y neuroblastoma cells.

Tanaka K, Tamiya-Koizumi K, Hagiwara K, Ito H, Takagi A, Kojima T, Suzuki M, Iwaki S, Fujii S, Nakamura M, Banno Y, Kannagi R, Tsurumi T, Kyogashima M, Murate T.

J Biochem. 2012 Jun;151(6):611-20. doi: 10.1093/jb/mvs033. Epub 2012 Mar 26.

PMID:
22451680
30.

Induction of 6-sulfated glycans with cell adhesion activity via T-bet and GATA-3 in human helper T cells.

Sakuma K, Chen GY, Aoki M, Kannagi R.

Biochim Biophys Acta. 2012 Jul;1820(7):841-8. doi: 10.1016/j.bbagen.2012.03.005. Epub 2012 Mar 14.

PMID:
22446378
31.

Quantitative transcriptomic profiling of branching in a glycosphingolipid biosynthetic pathway.

Takematsu H, Yamamoto H, Naito-Matsui Y, Fujinawa R, Tanaka K, Okuno Y, Tanaka Y, Kyogashima M, Kannagi R, Kozutsumi Y.

J Biol Chem. 2011 Aug 5;286(31):27214-24. doi: 10.1074/jbc.M111.234526. Epub 2011 Jun 10.

32.

Sialylated and sulfated carbohydrate ligands for selectins and siglecs: involvement in traffic and homing of human memory T and B lymphocytes.

Kannagi R, Ohmori K, Chen GY, Miyazaki K, Izawa M, Sakuma K.

Adv Exp Med Biol. 2011;705:549-69. doi: 10.1007/978-1-4419-7877-6_29. No abstract available.

PMID:
21618129
33.

TNFα enhances the motility and invasiveness of prostatic cancer cells by stimulating the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands.

Radhakrishnan P, Chachadi V, Lin MF, Singh R, Kannagi R, Cheng PW.

Biochem Biophys Res Commun. 2011 Jun 10;409(3):436-41. doi: 10.1016/j.bbrc.2011.05.019. Epub 2011 May 8.

34.

Kidney transplantation recovers the reduction level of serum sulfatide in ESRD patients via processes correlated to oxidative stress and platelet count.

Wang L, Kamijo Y, Matsumoto A, Nakajima T, Higuchi M, Kannagi R, Kyogashima M, Aoyama T, Hara A.

Glycoconj J. 2011 May;28(3-4):125-35. doi: 10.1007/s10719-011-9329-2. Epub 2011 Apr 19.

PMID:
21503857
35.

Systematic analyses of free ceramide species and ceramide species comprising neutral glycosphingolipids by MALDI-TOF MS with high-energy CID.

Tanaka K, Yamada M, Tamiya-Koizumi K, Kannagi R, Aoyama T, Hara A, Kyogashima M.

Glycoconj J. 2011 Feb;28(2):67-87. doi: 10.1007/s10719-011-9325-6. Epub 2011 Mar 12.

PMID:
21400001
36.

Cytoplasmic expression of the JM403 antigen GlcA-GlcNH3+ on heparan sulfate glycosaminoglycan in mammary carcinomas--a novel proliferative biomarker for breast cancers with high malignancy.

Fujii M, Yusa A, Yokoyama Y, Kokuryo T, Tsunoda N, Oda K, Nagino M, Ishimaru T, Shimoyama Y, Utsunomiya H, Iwata H, Itoh Y, Itoh J, Kannagi R, Kyogashima M.

Glycoconj J. 2010 Oct;27(7-9):661-72. doi: 10.1007/s10719-010-9311-4. Epub 2010 Nov 3.

PMID:
21046235
37.

[SLX(sialyl SSEA-1, sialyl Le(x)-i)].

Kannagi R, Izawa M, Sakuma K.

Nihon Rinsho. 2010 Jul;68 Suppl 7:720-5. Japanese. No abstract available.

PMID:
20960856
38.

[BCA225].

Kannagi R, Fujii M, Kumamoto K.

Nihon Rinsho. 2010 Jul;68 Suppl 7:709-13. Japanese. No abstract available.

PMID:
20960855
39.

[2 --> 6 sialyl Le(a) antigen].

Miyazaki K, Kannagi R.

Nihon Rinsho. 2010 Jul;68 Suppl 7:703-8. Japanese. No abstract available.

PMID:
20960854
40.

[STN (sialyl Tn antigen)].

Kannagi R.

Nihon Rinsho. 2010 Jul;68 Suppl 7:698-702. Japanese. No abstract available.

PMID:
20960853
41.

Epigenetic silencing of the sulfate transporter gene DTDST induces sialyl Lewisx expression and accelerates proliferation of colon cancer cells.

Yusa A, Miyazaki K, Kimura N, Izawa M, Kannagi R.

Cancer Res. 2010 May 15;70(10):4064-73. doi: 10.1158/0008-5472.CAN-09-2383. Epub 2010 May 11.

42.

Glycosylation Changes in Cancer.

Varki A, Kannagi R, Toole BP.

In: Varki A, Cummings RD, Esko JD, Freeze HH, Stanley P, Bertozzi CR, Hart GW, Etzler ME, editors. Essentials of Glycobiology. 2nd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009. Chapter 44.

43.

Sulfatides are associated with neointimal thickening after vascular injury.

Inoue T, Taguchi I, Abe S, Li G, Hu R, Nakajima T, Hara A, Aoyama T, Kannagi R, Kyogashima M, Node K.

Atherosclerosis. 2010 Jul;211(1):291-6. doi: 10.1016/j.atherosclerosis.2010.01.033. Epub 2010 Feb 2.

PMID:
20176357
44.

Altered expression of glycan genes in cancers induced by epigenetic silencing and tumor hypoxia: clues in the ongoing search for new tumor markers.

Kannagi R, Sakuma K, Miyazaki K, Lim KT, Yusa A, Yin J, Izawa M.

Cancer Sci. 2010 Mar;101(3):586-93. doi: 10.1111/j.1349-7006.2009.01455.x. Epub 2009 Dec 4. Review.

45.

Glycosphingolipids as mediators of phenotypic changes associated with development and cancer progression.

Igarashi Y, Kannagi R.

J Biochem. 2010 Jan;147(1):3-8. doi: 10.1093/jb/mvp195.

PMID:
20051388
46.

Expression of CC-chemokine receptor 7 (CCR7) and CXC-chemokine receptor 4 (CXCR4) in head and neck squamous cell carcinoma.

Ueda M, Shimada T, Goto Y, Tei K, Nakai S, Hisa Y, Kannagi R.

Auris Nasus Larynx. 2010 Aug;37(4):488-95. doi: 10.1016/j.anl.2009.11.012. Epub 2009 Dec 28.

PMID:
20036791
47.

Rap1 controls lymphocyte adhesion cascade and interstitial migration within lymph nodes in RAPL-dependent and -independent manners.

Ebisuno Y, Katagiri K, Katakai T, Ueda Y, Nemoto T, Inada H, Nabekura J, Okada T, Kannagi R, Tanaka T, Miyasaka M, Hogg N, Kinashi T.

Blood. 2010 Jan 28;115(4):804-14. doi: 10.1182/blood-2009-03-211979. Epub 2009 Nov 25.

PMID:
19965628
48.

Altered sphingolipid metabolism induced by tumor hypoxia - new vistas in glycolipid tumor markers.

Yin J, Miyazaki K, Shaner RL, Merrill AH Jr, Kannagi R.

FEBS Lett. 2010 May 3;584(9):1872-8. doi: 10.1016/j.febslet.2009.11.019. Epub 2009 Nov 11. Review.

49.

Acute kidney injury induced by protein-overload nephropathy down-regulates gene expression of hepatic cerebroside sulfotransferase in mice, resulting in reduction of liver and serum sulfatides.

Zhang X, Nakajima T, Kamijo Y, Li G, Hu R, Kannagi R, Kyogashima M, Aoyama T, Hara A.

Biochem Biophys Res Commun. 2009 Dec 25;390(4):1382-8. doi: 10.1016/j.bbrc.2009.10.164. Epub 2009 Nov 4.

PMID:
19895791
50.

Kidney dysfunction induced by protein overload nephropathy reduces serum sulfatide levels in mice.

Li G, Hu R, Kamijo Y, Nakajima T, Aoyama T, Ehara T, Shigematsu H, Kannagi R, Kyogashima M, Hara A.

Nephrology (Carlton). 2009 Oct;14(7):658-62. doi: 10.1111/j.1440-1797.2009.01116.x.

PMID:
19796024

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