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Items: 39


Hippo Signaling in Cancer: Lessons From Drosophila Models.

Snigdha K, Gangwani KS, Lapalikar GV, Singh A, Kango-Singh M.

Front Cell Dev Biol. 2019 May 24;7:85. doi: 10.3389/fcell.2019.00085. eCollection 2019. Review.


Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation.

Minata M, Audia A, Shi J, Lu S, Bernstock J, Pavlyukov MS, Das A, Kim SH, Shin YJ, Lee Y, Koo H, Snigdha K, Waghmare I, Guo X, Mohyeldin A, Gallego-Perez D, Wang J, Chen D, Cheng P, Mukheef F, Contreras M, Reyes JF, Vaillant B, Sulman EP, Cheng SY, Markert JM, Tannous BA, Lu X, Kango-Singh M, Lee LJ, Nam DH, Nakano I, Bhat KP.

Cell Rep. 2019 Feb 12;26(7):1893-1905.e7. doi: 10.1016/j.celrep.2019.01.076.


A soy protein Lunasin can ameliorate amyloid-beta 42 mediated neurodegeneration in Drosophila eye.

Sarkar A, Gogia N, Glenn N, Singh A, Jones G, Powers N, Srivastava A, Kango-Singh M, Singh A.

Sci Rep. 2018 Sep 10;8(1):13545. doi: 10.1038/s41598-018-31787-7.


Markers and Methods to Study Adult Midgut Stem Cells.

Pinto N, Carrington B, Dietrich C, Sinha R, Aguilar C, Chen T, Aggarwal P, Kango-Singh M, Singh SR.

Methods Mol Biol. 2018;1842:123-137. doi: 10.1007/978-1-4939-8697-2_9.


Cullin-4 regulates Wingless and JNK signaling-mediated cell death in the Drosophila eye.

Tare M, Sarkar A, Bedi S, Kango-Singh M, Singh A.

Cell Death Dis. 2016 Dec 29;7(12):e2566. doi: 10.1038/cddis.2016.338.


FOXD1-ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells.

Cheng P, Wang J, Waghmare I, Sartini S, Coviello V, Zhang Z, Kim SH, Mohyeldin A, Pavlyukov MS, Minata M, Valentim CL, Chhipa RR, Bhat KP, Dasgupta B, La Motta C, Kango-Singh M, Nakano I.

Cancer Res. 2016 Dec 15;76(24):7219-7230. Epub 2016 Aug 28.


Loss of Cell Adhesion Increases Tumorigenic Potential of Polarity Deficient Scribble Mutant Cells.

Waghmare I, Kango-Singh M.

PLoS One. 2016 Jun 21;11(6):e0158081. doi: 10.1371/journal.pone.0158081. eCollection 2016.


The Hippo pathway effector Yki downregulates Wg signaling to promote retinal differentiation in the Drosophila eye.

Wittkorn E, Sarkar A, Garcia K, Kango-Singh M, Singh A.

Development. 2015 Jun 1;142(11):2002-13. doi: 10.1242/dev.117358. Epub 2015 May 14.


Drosophila C-terminal Src kinase regulates growth via the Hippo signaling pathway.

Kwon HJ, Waghmare I, Verghese S, Singh A, Singh A, Kango-Singh M.

Dev Biol. 2015 Jan 1;397(1):67-76. doi: 10.1016/j.ydbio.2014.10.010. Epub 2014 Oct 22.


Intercellular cooperation and competition in brain cancers: lessons from Drosophila and human studies.

Waghmare I, Roebke A, Minata M, Kango-Singh M, Nakano I.

Stem Cells Transl Med. 2014 Nov;3(11):1262-8. doi: 10.5966/sctm.2014-0086. Epub 2014 Sep 17. Review.


Toxicity and localization studies of a potential photodynamic therapy agent in Drosophila.

Yoho J, Stroh C, Swavey S, Kango-Singh M.

Genesis. 2014 Apr;52(4):309-14. doi: 10.1002/dvg.22760. Epub 2014 Mar 12.


Homeotic Gene teashirt (tsh) has a neuroprotective function in amyloid-beta 42 mediated neurodegeneration.

Moran MT, Tare M, Kango-Singh M, Singh A.

PLoS One. 2013 Nov 25;8(11):e80829. doi: 10.1371/journal.pone.0080829. eCollection 2013.


Novel neuroprotective function of apical-basal polarity gene crumbs in amyloid beta 42 (aβ42) mediated neurodegeneration.

Steffensmeier AM, Tare M, Puli OR, Modi R, Nainaparampil J, Kango-Singh M, Singh A.

PLoS One. 2013 Nov 18;8(11):e78717. doi: 10.1371/journal.pone.0078717. eCollection 2013.


Genetic, immunofluorescence labeling, and in situ hybridization techniques in identification of stem cells in male and female germline niches.

Singh SR, Liu Y, Kango-Singh M, Nevo E.

Methods Mol Biol. 2013;1035:9-23. doi: 10.1007/978-1-62703-508-8_2.


Scribble acts in the Drosophila fat-hippo pathway to regulate warts activity.

Verghese S, Waghmare I, Kwon H, Hanes K, Kango-Singh M.

PLoS One. 2012;7(11):e47173. doi: 10.1371/journal.pone.0047173. Epub 2012 Nov 5.


Domain specific genetic mosaic system in the Drosophila eye.

Tare M, Puli OR, Moran MT, Kango-Singh M, Singh A.

Genesis. 2013 Jan;51(1):68-74. doi: 10.1002/dvg.22355. Epub 2012 Nov 26.


Generation and staining of intestinal stem cell lineage in adult midgut.

Singh SR, Mishra MK, Kango-Singh M, Hou SX.

Methods Mol Biol. 2012;879:47-69. doi: 10.1007/978-1-61779-815-3_4.


Annual Drosophila Research Conference, 2012.

Call GB, Roy Puli O, James AM, Pope CR, Kango-Singh M, Singh A.

Dev Dyn. 2012 Jul;241(7):1227-36. doi: 10.1002/dvdy.23806. Epub 2012 Jun 11. No abstract available.


Hippo signalling controls Dronc activity to regulate organ size in Drosophila.

Verghese S, Bedi S, Kango-Singh M.

Cell Death Differ. 2012 Oct;19(10):1664-76. doi: 10.1038/cdd.2012.48. Epub 2012 May 4.


Tumor suppression by cell competition through regulation of the Hippo pathway.

Chen CL, Schroeder MC, Kango-Singh M, Tao C, Halder G.

Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):484-9. doi: 10.1073/pnas.1113882109. Epub 2011 Dec 21.


A glimpse into dorso-ventral patterning of the Drosophila eye.

Singh A, Tare M, Puli OR, Kango-Singh M.

Dev Dyn. 2012 Jan;241(1):69-84. doi: 10.1002/dvdy.22764. Epub 2011 Oct 27. Review.


Activation of JNK signaling mediates amyloid-ß-dependent cell death.

Tare M, Modi RM, Nainaparampil JJ, Puli OR, Bedi S, Fernandez-Funez P, Kango-Singh M, Singh A.

PLoS One. 2011;6(9):e24361. doi: 10.1371/journal.pone.0024361. Epub 2011 Sep 14.


Opposing interactions between homothorax and Lobe define the ventral eye margin of Drosophila eye.

Singh A, Tare M, Kango-Singh M, Son WS, Cho KO, Choi KW.

Dev Biol. 2011 Nov 15;359(2):199-208. doi: 10.1016/j.ydbio.2011.08.017. Epub 2011 Sep 2.


Annual Drosophila research conference, 2011.

Call GB, Verghese S, Puli OR, Hemmerle DM, Kango-Singh M, Singh A.

Dev Dyn. 2011 Aug;240(8):2042-50. doi: 10.1002/dvdy.22689. No abstract available.


Dorsal eye selector pannier (pnr) suppresses the eye fate to define dorsal margin of the Drosophila eye.

Oros SM, Tare M, Kango-Singh M, Singh A.

Dev Biol. 2010 Oct 15;346(2):258-71. doi: 10.1016/j.ydbio.2010.07.030. Epub 2010 Aug 5.


Regulation of organ size: insights from the Drosophila Hippo signaling pathway.

Kango-Singh M, Singh A.

Dev Dyn. 2009 Jul;238(7):1627-37. doi: 10.1002/dvdy.21996. Review.


Annual Drosophila research conference, 2008.

Kango-Singh M, Call GB, Singh A.

Dev Dyn. 2008 Nov;237(11):3444-52. doi: 10.1002/dvdy.21737. No abstract available.


Larval legs of mulberry silkworm Bombyx mori are prototypes for the adult legs.

Singh A, Kango-Singh M, Parthasarathy R, Gopinathan KP.

Genesis. 2007 Apr;45(4):169-76.


The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.

Willecke M, Hamaratoglu F, Kango-Singh M, Udan R, Chen CL, Tao C, Zhang X, Halder G.

Curr Biol. 2006 Nov 7;16(21):2090-100. Epub 2006 Sep 21.


Annual Drosophila research conference, 2006.

Singh A, Kango-Singh M.

Dev Dyn. 2006 Oct;235(10):2900-4. No abstract available.


The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis.

Hamaratoglu F, Willecke M, Kango-Singh M, Nolo R, Hyun E, Tao C, Jafar-Nejad H, Halder G.

Nat Cell Biol. 2006 Jan;8(1):27-36. Epub 2005 Dec 11. Erratum in: Nat Cell Biol. 2006 Jan;8(1):100.


Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.

Eder AM, Sui X, Rosen DG, Nolden LK, Cheng KW, Lahad JP, Kango-Singh M, Lu KH, Warneke CL, Atkinson EN, Bedrosian I, Keyomarsi K, Kuo WL, Gray JW, Yin JC, Liu J, Halder G, Mills GB.

Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12519-24. Epub 2005 Aug 22.


Drosophila as an emerging model to study metastasis.

Kango-Singh M, Halder G.

Genome Biol. 2004;5(4):216. Epub 2004 Mar 25. Review.


Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway.

Udan RS, Kango-Singh M, Nolo R, Tao C, Halder G.

Nat Cell Biol. 2003 Oct;5(10):914-20. Epub 2003 Sep 21.


Eyeless collaborates with Hedgehog and Decapentaplegic signaling in Drosophila eye induction.

Kango-Singh M, Singh A, Henry Sun Y.

Dev Biol. 2003 Apr 1;256(1):49-60.


Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila.

Kango-Singh M, Nolo R, Tao C, Verstreken P, Hiesinger PR, Bellen HJ, Halder G.

Development. 2002 Dec;129(24):5719-30.


Eye suppression, a novel function of teashirt, requires Wingless signaling.

Singh A, Kango-Singh M, Sun YH.

Development. 2002 Sep;129(18):4271-80.


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