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Drug repositioning of TANK-binding kinase 1 inhibitor CYT387 as an alternative for the treatment of Gram-negative bacterial sepsis.

Lee SJ, Gharbi A, You JS, Han HD, Kang TH, Hong SH, Park WS, Jung ID, Park YM.

Int Immunopharmacol. 2019 Jun 4;73:482-490. doi: 10.1016/j.intimp.2019.05.051. [Epub ahead of print]


Endoplasmic reticulum stress enhances the antigen-specific T cell immune responses and therapeutic antitumor effects generated by therapeutic HPV vaccines.

Lee SY, Oh JY, Kang TH, Shin HS, Cheng MA, Farmer E, Wu TC, Hung CF.

J Biomed Sci. 2019 May 27;26(1):41. doi: 10.1186/s12929-019-0536-7.


Hydrogel-Templated Transfer-Printing of Conductive Nanonetworks for Wearable Sensors on Topographic Flexible Substrates.

Kang TH, Chang H, Choi D, Kim S, Moon J, Lim JA, Lee KY, Yi H.

Nano Lett. 2019 Jun 12;19(6):3684-3691. doi: 10.1021/acs.nanolett.9b00764. Epub 2019 May 23.


Wire-driven flexible manipulator with constrained spherical joints for minimally invasive surgery.

Ji D, Kang TH, Shim S, Lee S, Hong J.

Int J Comput Assist Radiol Surg. 2019 Apr 17. doi: 10.1007/s11548-019-01976-4. [Epub ahead of print]


An Engineered Human Fc variant With Exquisite Selectivity for FcγRIIIaV158 Reveals That Ligation of FcγRIIIa Mediates Potent Antibody Dependent Cellular Phagocytosis With GM-CSF-Differentiated Macrophages.

Kang TH, Lee CH, Delidakis G, Jung J, Richard-Le Goff O, Lee J, Kim JE, Charab W, Bruhns P, Georgiou G.

Front Immunol. 2019 Mar 27;10:562. doi: 10.3389/fimmu.2019.00562. eCollection 2019.


Panax ginseng (Korea Red Ginseng) repairs diabetic sensorineural damage through promotion of the nerve growth factor pathway in diabetic zebrafish.

Nam YH, Moon HW, Lee YR, Kim EY, Rodriguez I, Jeong SY, Castañeda R, Park JH, Choung SY, Hong BN, Kang TH.

J Ginseng Res. 2019 Apr;43(2):272-281. doi: 10.1016/j.jgr.2018.02.006. Epub 2018 Feb 16.


Electrophysiological changes in auditory evoked potentials in rats with salicylate-induced tinnitus.

Castañeda R, Natarajan S, Jeong SY, Hong BN, Kang TH.

Brain Res. 2019 Jul 15;1715:235-244. doi: 10.1016/j.brainres.2019.04.004. Epub 2019 Apr 5.


Pellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks.

Ha GH, Ji JH, Chae S, Park J, Kim S, Lee JK, Kim Y, Min S, Park JM, Kang TH, Lee H, Cho H, Lee CW.

Nat Commun. 2019 Apr 5;10(1):1577. doi: 10.1038/s41467-019-09641-9.


Repositioning of the antipsychotic drug TFP for sepsis treatment.

Park JH, Park HJ, Lee SE, Kim YS, Jang GY, Han HD, Jung ID, Shin KC, Bae YM, Kang TH, Park YM.

J Mol Med (Berl). 2019 May;97(5):647-658. doi: 10.1007/s00109-019-01762-4. Epub 2019 Mar 8.


A novel TLR4 binding protein, 40S ribosomal protein S3, has potential utility as an adjuvant in a dendritic cell-based vaccine.

Park HJ, Jang GY, Kim YS, Park JH, Lee SE, Vo MC, Lee JJ, Han HD, Jung ID, Kang TH, Park YM.

J Immunother Cancer. 2019 Feb 28;7(1):60. doi: 10.1186/s40425-019-0539-7.


Room Temperature Compressive Property and Deformation Behavior of Microporous STS 316L Stainless Steel Tube Manufactured with Powder Sintering Process.

Kang TH, Kim YK, Park MH, Lee KA.

J Nanosci Nanotechnol. 2019 Jul 1;19(7):4015-4019. doi: 10.1166/jnn.2019.16146.


Synergistic Effect of Two Major Components of Malva verticillata in the Recovery of Alloxan-Damaged Pancreatic Islet Cells in Zebrafish.

Ko JH, Rodriguez I, Joo SW, Kim HG, Lee YG, Kang TH, Baek NI.

J Med Food. 2019 Feb;22(2):196-201. doi: 10.1089/jmf.2018.4235.


Avocado Oil Extract Modulates Auditory Hair Cell Function through the Regulation of Amino Acid Biosynthesis Genes.

Nam YH, Rodriguez I, Jeong SY, Pham TNM, Nuankaew W, Kim YH, Castañeda R, Jeong SY, Park MS, Lee KW, Lee JS, Kim DH, Park YH, Kim SH, Moon IS, Choung SY, Hong BN, Jeong KW, Kang TH.

Nutrients. 2019 Jan 8;11(1). pii: E113. doi: 10.3390/nu11010113.


Optimization of self-microemulsifying drug delivery system for phospholipid complex of telmisartan using D-optimal mixture design.

Son HY, Chae BR, Choi JY, Shin DJ, Goo YT, Lee ES, Kang TH, Kim CH, Yoon HY, Choi YW.

PLoS One. 2018 Dec 5;13(12):e0208339. doi: 10.1371/journal.pone.0208339. eCollection 2018.


An Antibody Designed to Improve Adoptive NK-Cell Therapy Inhibits Pancreatic Cancer Progression in a Murine Model.

Lee J, Kang TH, Yoo W, Choi H, Jo S, Kong K, Lee SR, Kim SU, Kim JS, Cho D, Kim J, Kim JY, Kwon ES, Kim S.

Cancer Immunol Res. 2019 Feb;7(2):219-229. doi: 10.1158/2326-6066.CIR-18-0317. Epub 2018 Dec 4.


Traditional oriental medicine for sensorineural hearing loss: Can ethnopharmacology contribute to potential drug discovery?

Castañeda R, Natarajan S, Jeong SY, Hong BN, Kang TH.

J Ethnopharmacol. 2019 Mar 1;231:409-428. doi: 10.1016/j.jep.2018.11.016. Epub 2018 Nov 12. Review.


pH-sensitive PEGylation of RIPL peptide-conjugated nanostructured lipid carriers: design and in vitro evaluation.

Kim CH, Sa CK, Goh MS, Lee ES, Kang TH, Yoon HY, Battogtokh G, Ko YT, Choi YW.

Int J Nanomedicine. 2018 Oct 23;13:6661-6675. doi: 10.2147/IJN.S184355. eCollection 2018.


Roles of Tristetraprolin in Tumorigenesis.

Park JM, Lee TH, Kang TH.

Int J Mol Sci. 2018 Oct 29;19(11). pii: E3384. doi: 10.3390/ijms19113384. Review.


Sterically Stabilized RIPL Peptide-Conjugated Nanostructured Lipid Carriers: Characterization, Cellular Uptake, Cytotoxicity, and Biodistribution.

Kim CH, Sung SW, Lee ES, Kang TH, Yoon HY, Goo YT, Cho HR, Kim DY, Kang MJ, Choi YS, Lee S, Choi YW.

Pharmaceutics. 2018 Oct 23;10(4). pii: E199. doi: 10.3390/pharmaceutics10040199.


A novel function of API5 (apoptosis inhibitor 5), TLR4-dependent activation of antigen presenting cells.

Kim YS, Park HJ, Park JH, Hong EJ, Jang GY, Jung ID, Han HD, Lee SH, Vo MC, Lee JJ, Yang A, Farmer E, Wu TC, Kang TH, Park YM.

Oncoimmunology. 2018 Aug 15;7(10):e1472187. doi: 10.1080/2162402X.2018.1472187. eCollection 2018.


Glycerides isolated from the aerial parts of Malva verticillata cause immunomodulation effects via splenocyte function and NK anti-tumor activity.

Ko JH, Castaneda R, Joo SW, Kim HG, Lee YG, Lee YH, Kang TH, Baek NI.

Food Sci Biotechnol. 2018 Feb 28;27(4):1023-1030. doi: 10.1007/s10068-018-0344-y. eCollection 2018 Aug.


Hydrodynamic Layer-by-Layer Assembly of Transferable Enzymatic Conductive Nanonetworks for Enzyme-Sticker-Based Contact Printing of Electrochemical Biosensors.

Lee SW, Kang TH, Lee SK, Lee KY, Yi H.

ACS Appl Mater Interfaces. 2018 Oct 24;10(42):36267-36274. doi: 10.1021/acsami.8b13070. Epub 2018 Oct 11.


CD44-Targeting PLGA Nanoparticles Incorporating Paclitaxel and FAK siRNA Overcome Chemoresistance in Epithelial Ovarian Cancer.

Byeon Y, Lee JW, Choi WS, Won JE, Kim GH, Kim MG, Wi TI, Lee JM, Kang TH, Jung ID, Cho YJ, Ahn HJ, Shin BC, Lee YJ, Sood AK, Han HD, Park YM.

Cancer Res. 2018 Nov 1;78(21):6247-6256. doi: 10.1158/0008-5472.CAN-17-3871. Epub 2018 Aug 16.


Elevated expression of pancreatic adenocarcinoma upregulated factor (PAUF) is associated with poor prognosis and chemoresistance in epithelial ovarian cancer.

Choi CH, Kang TH, Song JS, Kim YS, Chung EJ, Ylaya K, Kim S, Koh SS, Chung JY, Kim JH, Hewitt SM.

Sci Rep. 2018 Aug 15;8(1):12161. doi: 10.1038/s41598-018-30582-8.


Selective delivery of PLXDC1 small interfering RNA to endothelial cells for anti-angiogenesis tumor therapy using CD44-targeted chitosan nanoparticles for epithelial ovarian cancer.

Kim GH, Won JE, Byeon Y, Kim MG, Wi TI, Lee JM, Park YY, Lee JW, Kang TH, Jung ID, Shin BC, Ahn HJ, Lee YJ, Sood AK, Han HD, Park YM.

Drug Deliv. 2018 Nov;25(1):1394-1402. doi: 10.1080/10717544.2018.1480672.


Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.

Park HJ, Lee SJ, Cho J, Gharbi A, Han HD, Kang TH, Kim Y, Lee Y, Park WS, Jung ID, Park YM.

J Nat Prod. 2018 Jun 22;81(6):1435-1443. doi: 10.1021/acs.jnatprod.8b00155. Epub 2018 May 31.


PD-1/PD-L1 and immune-related gene expression pattern in pediatric malignant brain tumors: clinical correlation with survival data in Korean population.

Hwang K, Koh EJ, Choi EJ, Kang TH, Han JH, Choe G, Park SH, Yearley JH, Annamalai L, Blumenschein W, Sathe M, McClanahan T, Jung H, Wang KC, Kim SK, Kim CY.

J Neurooncol. 2018 Sep;139(2):281-291. doi: 10.1007/s11060-018-2886-5. Epub 2018 May 5.


Association of miR-149 polymorphism with onset age and severity in Charcot-Marie-Tooth disease type 1A.

Nam SH, Kanwal S, Nam DE, Lee MH, Kang TH, Jung SC, Choi BO, Chung KW.

Neuromuscul Disord. 2018 Jun;28(6):502-507. doi: 10.1016/j.nmd.2018.04.002. Epub 2018 Apr 11.


Flavonoid 8-O-Glucuronides from the Aerial Parts of Malva verticillata and Their Recovery Effects on Alloxan-Induced Pancreatic Islets in Zebrafish.

Ko JH, Nam YH, Joo SW, Kim HG, Lee YG, Kang TH, Baek NI.

Molecules. 2018 Apr 4;23(4). pii: E833. doi: 10.3390/molecules23040833.


An Unusual Case of Meningioma Showing Increased CaSR Expression with Parathyroid Carcinoma.

Yoo JS, Kim HM, Kim S, Kang TH, Cho MY, Chung CH.

Endocrinol Metab (Seoul). 2018 Mar;33(1):133-134. doi: 10.3803/EnM.2018.33.1.133. Epub 2018 Jan 30. No abstract available.


Skin depigmenting action of silkworm (Bombyx mori L.) droppings in zebrafish.

Lee YR, Park JH, Castaneda Molina R, Nam YH, Lee YG, Hong BN, Baek NI, Kang TH.

Arch Dermatol Res. 2018 Apr;310(3):245-253. doi: 10.1007/s00403-018-1804-1. Epub 2018 Jan 22.


Non-genetic engineering of cytotoxic T cells to target IL-4 receptor enhances tumor homing and therapeutic efficacy against melanoma.

Gunassekaran GR, Hong CM, Vadevoo SMP, Chi L, Guruprasath P, Ahn BC, Kim HJ, Kang TH, Lee B.

Biomaterials. 2018 Mar;159:161-173. doi: 10.1016/j.biomaterials.2018.01.013. Epub 2018 Jan 8.


Trigonelline promotes auditory function through nerve growth factor signaling on diabetic animal models.

Castañeda R, Rodriguez I, Nam YH, Hong BN, Kang TH.

Phytomedicine. 2017 Dec 1;36:128-136. doi: 10.1016/j.phymed.2017.09.023. Epub 2017 Oct 11.


Genetic structure and demographic history of Lymantria dispar (Linnaeus, 1758) (Lepidoptera: Erebidae) in its area of origin and adjacent areas.

Kang TH, Han SH, Lee HS.

Ecol Evol. 2017 Sep 30;7(21):9162-9178. doi: 10.1002/ece3.3467. eCollection 2017 Nov.


Hydrogenated MoS2 QD-TiO2 heterojunction mediated efficient solar hydrogen production.

Saha A, Sinhamahapatra A, Kang TH, Ghosh SC, Yu JS, Panda AB.

Nanoscale. 2017 Nov 9;9(43):17029-17036. doi: 10.1039/c7nr06526d.


Natural Compound Licochalcone B Induced Extrinsic and Intrinsic Apoptosis in Human Skin Melanoma (A375) and Squamous Cell Carcinoma (A431) Cells.

Kang TH, Yoon G, Kang IA, Oh HN, Chae JI, Shim JH.

Phytother Res. 2017 Dec;31(12):1858-1867. doi: 10.1002/ptr.5928. Epub 2017 Oct 13.


Corrigendum: IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions.

Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, Triplett K, Donkor M, Lungu OI, Lux A, Marshall N, Lindorfer MA, Goff OR, Balbino B, Kang TH, Tanno H, Delidakis G, Alford C, Taylor RP, Nimmerjahn F, Varadarajan N, Bruhns P, Zhang YJ, Georgiou G.

Nat Immunol. 2017 Sep 19;18(10):1173. doi: 10.1038/ni1017-1173c. No abstract available.


Urine to highly porous heteroatom-doped carbons for supercapacitor: A value added journey for human waste.

Razmjooei F, Singh K, Kang TH, Chaudhari N, Yuan J, Yu JS.

Sci Rep. 2017 Sep 7;7(1):10910. doi: 10.1038/s41598-017-11229-6.


Redox-Triggered Coloration Mechanism of Electrically Tunable Colloidal Photonic Crystals.

Yang HS, Jang J, Lee BS, Kang TH, Park JJ, Yu WR.

Langmuir. 2017 Sep 12;33(36):9057-9065. doi: 10.1021/acs.langmuir.7b01919. Epub 2017 Aug 24.


Bioconversion of Scutellaria baicalensis extract can increase recovery of auditory function in a mouse model of noise-induced hearing loss.

Rodriguez I, Hong BN, Nam YH, Kim EY, Park GH, Ji MG, Kang TH.

Biomed Pharmacother. 2017 Sep;93:1303-1309. doi: 10.1016/j.biopha.2017.07.069. Epub 2017 Jul 23.


IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions.

Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, Triplett K, Donkor M, Lungu OI, Lux A, Marshall N, Lindorfer MA, Goff OR, Balbino B, Kang TH, Tanno H, Delidakis G, Alford C, Taylor RP, Nimmerjahn F, Varadarajan N, Bruhns P, Zhang YJ, Georgiou G.

Nat Immunol. 2017 Aug;18(8):889-898. doi: 10.1038/ni.3770. Epub 2017 Jun 12. Erratum in: Nat Immunol. 2017 Sep 19;18(10 ):1173.


Synthesis of Water-Dispersible Single-Layer CoAl-Carbonate Layered Double Hydroxide.

Li H, Tran TN, Lee BJ, Zhang C, Park JD, Kang TH, Yu JS.

ACS Appl Mater Interfaces. 2017 Jun 21;9(24):20294-20298. doi: 10.1021/acsami.7b02912. Epub 2017 Jun 8.


Antifungal Activities of Dimeric Sesquiterpenes, Shizukaols C and F, Isolated from Chloranthus japonicus Sieb.

Kang TH, Lee YM, Lee WJ, Hwang EI, Park KD, Choi GJ, Moon JS, Park HY, Kim SU.

J Microbiol Biotechnol. 2017 Jul 28;27(7):1272-1275. doi: 10.4014/jmb.1612.12051.


Licochalcone A Suppresses Specificity Protein 1 as a Novel Target in Human Breast Cancer Cells.

Kang TH, Seo JH, Oh H, Yoon G, Chae JI, Shim JH.

J Cell Biochem. 2017 Dec;118(12):4652-4663. doi: 10.1002/jcb.26131. Epub 2017 Jun 12.


Synthetic vaccine nanoparticles target to lymph node triggering enhanced innate and adaptive antitumor immunity.

Kim SY, Noh YW, Kang TH, Kim JE, Kim S, Um SH, Oh DB, Park YM, Lim YT.

Biomaterials. 2017 Jun;130:56-66. doi: 10.1016/j.biomaterials.2017.03.034. Epub 2017 Mar 26.


Neoagarooligosaccharides prevent septic shock by modulating A20-and cyclooxygenase-2-mediated interleukin-10 secretion in a septic-shock mouse model.

Kang DR, Yoon GY, Cho J, Lee SJ, Lee SJ, Park HJ, Kang TH, Han HD, Park WS, Yoon YK, Park YM, Jung ID.

Biochem Biophys Res Commun. 2017 May 13;486(4):998-1004. doi: 10.1016/j.bbrc.2017.03.152. Epub 2017 Mar 28.


Neoagarohexaose-mediated activation of dendritic cells via Toll-like receptor 4 leads to stimulation of natural killer cells and enhancement of antitumor immunity.

Lee MH, Jang JH, Yoon GY, Lee SJ, Lee MG, Kang TH, Han HD, Kim HS, Choi WS, Park WS, Park YM, Jung ID.

BMB Rep. 2017 May;50(5):263-268.


Protein adsorption of dialdehyde cellulose-crosslinked chitosan with high amino group contents.

Kim UJ, Lee YR, Kang TH, Choi JW, Kimura S, Wada M.

Carbohydr Polym. 2017 May 1;163:34-42. doi: 10.1016/j.carbpol.2017.01.052. Epub 2017 Jan 18.


Enhanced antidiabetic efficacy and safety of compound K⁄β-cyclodextrin inclusion complex in zebrafish.

Nam YH, Le HT, Rodriguez I, Kim EY, Kim K, Jeong SY, Woo SH, Lee YR, Castañeda R, Hong J, Ji MG, Kim UJ, Hong BN, Kim TW, Kang TH.

J Ginseng Res. 2017 Jan;41(1):103-112. doi: 10.1016/j.jgr.2016.08.007. Epub 2016 Aug 23.


Chlorogenic acid rescues sensorineural auditory function in a diabetic animal model.

Hong BN, Nam YH, Woo SH, Kang TH.

Neurosci Lett. 2017 Feb 15;640:64-69. doi: 10.1016/j.neulet.2017.01.030. Epub 2017 Jan 16.


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