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Suppression of Postprandial Blood Glucose Fluctuations by a Low-Carbohydrate, High-Protein, and High-Omega-3 Diet via Inhibition of Gluconeogenesis.

Wang B, Smyl C, Chen CY, Li XY, Huang W, Zhang HM, Pai VJ, Kang JX.

Int J Mol Sci. 2018 Jun 21;19(7). pii: E1823. doi: 10.3390/ijms19071823.


Enriched Brain Omega-3 Polyunsaturated Fatty Acids Confer Neuroprotection against Microinfarction.

Luo C, Ren H, Yao X, Shi Z, Liang F, Kang JX, Wan JB, Pei Z, Su KP, Su H.

EBioMedicine. 2018 Jun;32:50-61. doi: 10.1016/j.ebiom.2018.05.028. Epub 2018 Jun 5.


Maternal omega-3 fatty acids regulate offspring obesity through persistent modulation of gut microbiota.

Robertson RC, Kaliannan K, Strain CR, Ross RP, Stanton C, Kang JX.

Microbiome. 2018 May 24;6(1):95. doi: 10.1186/s40168-018-0476-6.


Amelioration of UVB-induced oxidative stress and inflammation in fat-1 transgenic mouse skin.

Yum HW, Kim SH, Kang JX, Surh YJ.

Biochem Biophys Res Commun. 2018 Jul 7;502(1):1-8. doi: 10.1016/j.bbrc.2018.05.093. Epub 2018 May 25.


Acetaminophen-induced liver injury is attenuated in transgenic fat-1 mice endogenously synthesizing long-chain n-3 fatty acids.

Feng R, Wang Y, Liu C, Yan C, Zhang H, Su H, Kang JX, Shang CZ, Wan JB.

Biochem Pharmacol. 2018 Apr 18;154:75-88. doi: 10.1016/j.bcp.2018.04.019. [Epub ahead of print]


miR-424 protects PC-12 cells from OGD-induced injury by negatively regulating MKP-1.

Cao YX, Wang ZQ, Kang JX, Liu K, Zhao CF, Guo YX, Jiao BH.

Eur Rev Med Pharmacol Sci. 2018 Mar;22(5):1426-1436. doi: 10.26355/eurrev_201803_14490.


Identification of a sustainable two-plant diet that effectively prevents age-related metabolic syndrome and extends lifespan in aged mice.

Li XY, Liu YH, Wang B, Chen CY, Zhang HM, Kang JX.

J Nutr Biochem. 2018 Jan;51:16-26. doi: 10.1016/j.jnutbio.2017.09.003. Epub 2017 Sep 19.


Balanced Diet-Fed Fat-1 Transgenic Mice Exhibit Lower Hindlimb Suspension-Induced Soleus Muscle Atrophy.

Marzuca-Nassr GN, Murata GM, Martins AR, Vitzel KF, Crisma AR, Torres RP, Mancini-Filho J, Kang JX, Curi R.

Nutrients. 2017 Oct 6;9(10). pii: E1100. doi: 10.3390/nu9101100.


Endogenous ω-3 Fatty Acid Production by fat-1 Transgene and Topically Applied Docosahexaenoic Acid Protect against UVB-induced Mouse Skin Carcinogenesis.

Yum HW, Park J, Park HJ, Shin JW, Cho YY, Kim SJ, Kang JX, Surh YJ.

Sci Rep. 2017 Sep 14;7(1):11658. doi: 10.1038/s41598-017-11443-2.


Omega-3 polyunsaturated fatty acids ameliorate ethanol-induced adipose hyperlipolysis: A mechanism for hepatoprotective effect against alcoholic liver disease.

Wang M, Zhang X, Ma LJ, Feng RB, Yan C, Su H, He C, Kang JX, Liu B, Wan JB.

Biochim Biophys Acta. 2017 Dec;1863(12):3190-3201. doi: 10.1016/j.bbadis.2017.08.026. Epub 2017 Aug 25.


Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity.

Ramos-Lopez O, Milagro FI, Allayee H, Chmurzynska A, Choi MS, Curi R, De Caterina R, Ferguson LR, Goni L, Kang JX, Kohlmeier M, Marti A, Moreno LA, Pérusse L, Prasad C, Qi L, Reifen R, Riezu-Boj JI, San-Cristobal R, Santos JL, Martínez JA.

J Nutrigenet Nutrigenomics. 2017;10(1-2):43-62. doi: 10.1159/000477729. Epub 2017 Jul 8.


Constitutive ω-3 fatty acid production in fat-1 transgenic mice and docosahexaenoic acid administration to wild type mice protect against 2,4,6-trinitrobenzene sulfonic acid-induced colitis.

Yum HW, Kang JX, Hahm KB, Surh YJ.

Biochem Biophys Res Commun. 2017 Jun 10;487(4):847-855. doi: 10.1016/j.bbrc.2017.04.140. Epub 2017 Apr 26.


Radiation Resistance in KRAS-Mutated Lung Cancer Is Enabled by Stem-like Properties Mediated by an Osteopontin-EGFR Pathway.

Wang M, Han J, Marcar L, Black J, Liu Q, Li X, Nagulapalli K, Sequist LV, Mak RH, Benes CH, Hong TS, Gurtner K, Krause M, Baumann M, Kang JX, Whetstine JR, Willers H.

Cancer Res. 2017 Apr 15;77(8):2018-2028. doi: 10.1158/0008-5472.CAN-16-0808. Epub 2017 Feb 15.


Protection against fine particle-induced pulmonary and systemic inflammation by omega-3 polyunsaturated fatty acids.

Li XY, Hao L, Liu YH, Chen CY, Pai VJ, Kang JX.

Biochim Biophys Acta. 2017 Mar;1861(3):577-584. doi: 10.1016/j.bbagen.2016.12.018. Epub 2016 Dec 21.


Enriched Endogenous Omega-3 Polyunsaturated Fatty Acids Protect Cortical Neurons from Experimental Ischemic Injury.

Shi Z, Ren H, Luo C, Yao X, Li P, He C, Kang JX, Wan JB, Yuan TF, Su H.

Mol Neurobiol. 2016 Nov;53(9):6482-6488. doi: 10.1007/s12035-015-9554-y. Epub 2015 Nov 26.


Omega-3 polyunsaturated fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system.

Ren H, Luo C, Feng Y, Yao X, Shi Z, Liang F, Kang JX, Wan JB, Pei Z, Su H.

FASEB J. 2017 Jan;31(1):282-293. doi: 10.1096/fj.201600896. Epub 2016 Oct 7.


Three New Cytotoxic Polyhydroxysteroidal Glycosides from Starfish Craspidaster hesperus.

Kang JX, Kang YF, Han H.

Mar Drugs. 2016 Oct 19;14(10). pii: E189.


Mitigation of indomethacin-induced gastrointestinal damages in fat-1 transgenic mice via gate-keeper action of ω-3-polyunsaturated fatty acids.

Han YM, Park JM, Kang JX, Cha JY, Lee HJ, Jeong M, Go EJ, Hahm KB.

Sci Rep. 2016 Sep 23;6:33992. doi: 10.1038/srep33992.


Endogenously synthesized n-3 fatty acids in fat-1 transgenic mice prevent melanoma progression by increasing E-cadherin expression and inhibiting β-catenin signaling.

Yin X, Yu XW, Zhu P, Zhang YM, Zhang XH, Wang F, Zhang JJ, Yan W, Xi Y, Wan JB, Kang JX, Zou ZQ, Bu SZ.

Mol Med Rep. 2016 Oct;14(4):3476-84. doi: 10.3892/mmr.2016.5639. Epub 2016 Aug 18.


Suppressed Helicobacter pylori-associated gastric tumorigenesis in Fat-1 transgenic mice producing endogenous ω-3 polyunsaturated fatty acids.

Han YM, Kim KJ, Jeong M, Park JM, Go EJ, Kang JX, Hong SP, Hahm KB.

Oncotarget. 2016 Oct 11;7(41):66606-66622. doi: 10.18632/oncotarget.11261.

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