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Precise detection of low-level somatic mutation in resected epilepsy brain tissue.

Sim NS, Ko A, Kim WK, Kim SH, Kim JS, Shim KW, Aronica E, Mijnsbergen C, Spliet WGM, Koh HY, Kim HD, Lee JS, Kim DS, Kang HC, Lee JH.

Acta Neuropathol. 2019 Aug 3. doi: 10.1007/s00401-019-02052-6. [Epub ahead of print]


Effects of light and temperature on the growth of Takayama helix (Dinophyceae): mixotrophy as a survival strategy against photoinhibition.

Ok JH, Jeong HJ, Lim AS, You JH, Kang HC, Kim SJ, Lee SY.

J Phycol. 2019 Jul 29. doi: 10.1111/jpy.12907. [Epub ahead of print]


The clinical meaning of pre- and post-ablation thyroglobulin levels at first radioiodine therapy in patients with papillary thyroid cancer.

Kim HK, Yoon JH, Cho JS, Kwon SY, Yoo SW, Kang HC.

Korean J Intern Med. 2019 Jul 29. doi: 10.3904/kjim.2018.173. [Epub ahead of print]


Identification of Catalposide Metabolites in Human Liver and Intestinal Preparations and Characterization of the Relevant Sulfotransferase, UDP-glucuronosyltransferase, and Carboxylesterase Enzymes.

Hwang DK, Kim JH, Shin Y, Choi WG, Kim S, Cho YY, Lee JY, Kang HC, Lee HS.

Pharmaceutics. 2019 Jul 22;11(7). pii: E355. doi: 10.3390/pharmaceutics11070355.


Short- and long-term seizure-free outcomes of dietary treatment in infants according to etiology.

Riantarini I, Kim HD, Ko A, Kim SH, Kang HC, Lee JS, Jung DE.

Seizure. 2019 Jun 4;71:100-104. doi: 10.1016/j.seizure.2019.06.002. [Epub ahead of print]


Efficacy and Safety of Omega-3 Fatty Acids in Patients Treated with Statins for Residual Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Jun JE, Jeong IK, Yu JM, Kim SR, Lee IK, Han KA, Choi SH, Kim SK, Park HK, Mok JO, Lee YH, Kwon HS, Kim SH, Kang HC, Lee SA, Lee CB, Choi KM, Her SH, Shin WY, Shin MS, Ahn HS, Kang SH, Cho JM, Jo SH, Cha TJ, Kim SY, Won KH, Kim DB, Lee JH, Lee MK.

Diabetes Metab J. 2019 Jun 20. doi: 10.4093/dmj.2018.0265. [Epub ahead of print]


Epigallocatechin-3-Gallate Prevents Acute Gout by Suppressing NLRP3 Inflammasome Activation and Mitochondrial DNA Synthesis.

Lee HE, Yang G, Park YB, Kang HC, Cho YY, Lee HS, Lee JY.

Molecules. 2019 Jun 6;24(11). pii: E2138. doi: 10.3390/molecules24112138.


Effect of changes in monitor unit rate and energy on dose rate of total marrow irradiation based on Linac volumetric arc therapy.

Son J, Choi N, Kim JI, Park JM, Wu HG, Kang HC, Choi CH.

Radiat Oncol. 2019 May 27;14(1):87. doi: 10.1186/s13014-019-1296-y.


Clobazam as an adjunctive treatment for infantile spasms.

Hahn J, Lee H, Kang HC, Lee JS, Kim HD, Kim SH, Chang MJ.

Epilepsy Behav. 2019 Jun;95:161-165. doi: 10.1016/j.yebeh.2019.03.040. Epub 2019 May 4.


A meta-analysis of the impact of neutrophil-to-lymphocyte ratio on treatment outcomes after radiotherapy for solid tumors.

Choi N, Kim JH, Chie EK, Gim J, Kang HC.

Medicine (Baltimore). 2019 May;98(18):e15369. doi: 10.1097/MD.0000000000015369.


RSK2-Mediated ELK3 Activation Enhances Cell Transformation and Breast Cancer Cell Growth by Regulation of c-fos Promoter Activity.

Yoo SM, Lee CJ, An HJ, Lee JY, Lee HS, Kang HC, Cho SJ, Kim SM, Park J, Kim DJ, Cho YY.

Int J Mol Sci. 2019 Apr 23;20(8). pii: E1994. doi: 10.3390/ijms20081994.


Differential feeding by common heterotrophic protists on four Scrippsiella species of similar size.

Kim SJ, Jeong HJ, Kang HC, You JH, Ok JH.

J Phycol. 2019 Aug;55(4):868-881. doi: 10.1111/jpy.12864. Epub 2019 Jul 10.


Aligned Brain Extracellular Matrix Promotes Differentiation and Myelination of Human-Induced Pluripotent Stem Cell-Derived Oligodendrocytes.

Cho AN, Jin Y, Kim S, Kumar S, Shin H, Kang HC, Cho SW.

ACS Appl Mater Interfaces. 2019 May 1;11(17):15344-15353. doi: 10.1021/acsami.9b03242. Epub 2019 Apr 22.


Proband-Only Clinical Exome Sequencing for Neurodevelopmental Disabilities.

Kim SH, Kim B, Lee JS, Kim HD, Choi JR, Lee ST, Kang HC.

Pediatr Neurol. 2019 Feb 27. pii: S0887-8994(18)31348-1. doi: 10.1016/j.pediatrneurol.2019.02.017. [Epub ahead of print]


Three-dimensional brain-like microenvironments facilitate the direct reprogramming of fibroblasts into therapeutic neurons.

Jin Y, Lee JS, Kim J, Min S, Wi S, Yu JH, Chang GE, Cho AN, Choi Y, Ahn DH, Cho SR, Cheong E, Kim YG, Kim HP, Kim Y, Kim DS, Kim HW, Quan Z, Kang HC, Cho SW.

Nat Biomed Eng. 2018 Jul;2(7):522-539. doi: 10.1038/s41551-018-0260-8. Epub 2018 Jul 11.


A 6-year Prospective, Observational, Multi-Center Post-Marketing Surveillance of the Safety of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis (Tdap) Vaccine in Korea.

Park HJ, Kim SJ, Song R, Chen J, Kim JH, Devadiga R, Kang HC.

J Korean Med Sci. 2019 Mar 22;34(12):e105. doi: 10.3346/jkms.2019.34.e105. eCollection 2019 Apr 1.


Generation of an induced pluripotent stem cell (iPSC) line from a 42-year-old adult cerebral type X-linked adrenoleukodystrophy (X-ALD) patient.

Yeon GB, Son D, Kang PJ, Oh SM, Lim H, Kang HC, You S, Kim DS.

Stem Cell Res. 2019 Apr;36:101425. doi: 10.1016/j.scr.2019.101425. Epub 2019 Mar 21.


Epimagnolin targeting on an active pocket of mammalian target of rapamycin suppressed cell transformation and colony growth of lung cancer cells.

Yoo SM, Lee CJ, Kang HC, Lee HS, Lee JY, Kim KD, Kim DJ, An HJ, Cho YY.

Mol Carcinog. 2019 Jul;58(7):1221-1233. doi: 10.1002/mc.23005. Epub 2019 Mar 18.


Medication self-management and the quality of discharge education among parents of children with epilepsy.

Lee HJ, Choi EK, Kim HS, Kang HC.

Epilepsy Behav. 2019 May;94:14-19. doi: 10.1016/j.yebeh.2018.12.030. Epub 2019 Mar 15.


The use of technical replication for detection of low-level somatic mutations in next-generation sequencing.

Kim J, Kim D, Lim JS, Maeng JH, Son H, Kang HC, Nam H, Lee JH, Kim S.

Nat Commun. 2019 Mar 5;10(1):1047. doi: 10.1038/s41467-019-09026-y.


In Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)-N-(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography⁻Mass Spectrometry.

Kim JH, Kim S, Lee J, In S, Cho YY, Kang HC, Lee JY, Lee HS.

Molecules. 2019 Feb 25;24(4). pii: E818. doi: 10.3390/molecules24040818.


A phthalimidoalkanamide derived novel DNMT inhibitor enhanced radiosensitivity of A549 cells by inhibition of homologous recombination of DNA damage.

Kang HC, Chie EK, Kim HJ, Kim JH, Kim IH, Kim K, Shin BS, Ma E.

Invest New Drugs. 2019 Feb 22. doi: 10.1007/s10637-019-00730-6. [Epub ahead of print]


Radiosensitization of Glioblastoma Cells by a Novel DNA Methyltransferase-inhibiting Phthalimido-Alkanamide Derivative.

Wee CW, Kim JH, Kim HJ, Kang HC, Suh SY, Shin BS, Ma E, Kim IH.

Anticancer Res. 2019 Feb;39(2):759-769. doi: 10.21873/anticanres.13173.


Anti-Aging Activity of Lavandula angustifolia Extract Fermented with Pediococcus pentosaceus DK1 Isolated from Diospyros kaki Fruit in UVB-Irradiated Human Skin Fibroblasts and Analysis of Principal Components.

Ha JH, Kim AR, Lee KS, Xuan SH, Kang HC, Lee DH, Cha MY, Kim HJ, An M, Park SN.

J Microbiol Biotechnol. 2019 Jan 28;29(1):21-29. doi: 10.4014/jmb.1809.09037.


Brain somatic mutations in SLC35A2 cause intractable epilepsy with aberrant N-glycosylation.

Sim NS, Seo Y, Lim JS, Kim WK, Son H, Kim HD, Kim S, An HJ, Kang HC, Kim SH, Kim DS, Lee JH.

Neurol Genet. 2018 Dec 5;4(6):e294. doi: 10.1212/NXG.0000000000000294. eCollection 2018 Dec.


Drp1-Zip1 Interaction Regulates Mitochondrial Quality Surveillance System.

Cho HM, Ryu JR, Jo Y, Seo TW, Choi YN, Kim JH, Chung JM, Cho B, Kang HC, Yu SW, Yoo SJ, Kim H, Sun W.

Mol Cell. 2019 Jan 17;73(2):364-376.e8. doi: 10.1016/j.molcel.2018.11.009. Epub 2018 Dec 20.


A Child With Lymphangioma Due to Somatic Mutation in PIK3CA Successfully Treated With Everolimus.

Park S, Kim SH, Youn SE, Lee ST, Kang HC.

Pediatr Neurol. 2019 Feb;91:65-67. doi: 10.1016/j.pediatrneurol.2018.10.017. Epub 2018 Nov 22. No abstract available.


Continuous nursing intervention on recovery of diabetic patients.

Chi S, Liu JL, Kang HC, Lv DM.

J Biol Regul Homeost Agents. 2018 Nov-Dec;32(6):1507-1513.


Eighth edition of tumor-node-metastasis staging system improve survival predictability for papillary, but not follicular thyroid carcinoma: A multicenter cohort study.

Kim M, Kim HI, Jeon MJ, Kim HK, Kim EH, Yi HS, Kim ES, Kim H, Kim BH, Kim TY, Kim SW, Kang HC, Kim WB, Chung JH, Shong YK, Kim TH, Kim WG.

Oral Oncol. 2018 Dec;87:97-103. doi: 10.1016/j.oraloncology.2018.10.029. Epub 2018 Oct 26.


Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives.

Battogtokh G, Choi YS, Kang DS, Park SJ, Shim MS, Huh KM, Cho YY, Lee JY, Lee HS, Kang HC.

Acta Pharm Sin B. 2018 Oct;8(6):862-880. doi: 10.1016/j.apsb.2018.05.006. Epub 2018 May 18. Review.


Epilepsy Surgery for Children With Low-Grade Epilepsy-Associated Tumors: Factors Associated With Seizure Recurrence and Cognitive Function.

Ko A, Kim SH, Kim SH, Park EK, Shim KW, Kang HC, Kim DS, Kim HD, Lee JS.

Pediatr Neurol. 2019 Feb;91:50-56. doi: 10.1016/j.pediatrneurol.2018.10.008. Epub 2018 Oct 24.


Mitochondria-targeting theranostics.

Kang HC.

Biomater Res. 2018 Nov 8;22:34. doi: 10.1186/s40824-018-0145-7. eCollection 2018. Review.


Modification of the eight-edition tumor-node-metastasis staging system with N1b for papillary thyroid carcinoma: A multi-institutional cohort study.

Kim M, Kim HK, Kim HI, Kim EH, Jeon MJ, Yi HS, Kim ES, Kim H, Kim TH, Kim BH, Kim TY, Kang HC, Kim WB, Chung JH, Shong YK, Kim SW, Kim WG.

Oral Oncol. 2018 Nov;86:48-52. doi: 10.1016/j.oraloncology.2018.09.008. Epub 2018 Sep 13.


Interregional metabolic connectivity of 2-deoxy-2[18 F]fluoro-D-glucose positron emission tomography in vagus nerve stimulation for pediatric patients with epilepsy: A retrospective cross-sectional study.

Yu R, Park HJ, Cho H, Ko A, Pae C, Oh MK, Kang HC, Kim HD, Park EK, Shim KW, Kim DS, Lee JS.

Epilepsia. 2018 Dec;59(12):2249-2259. doi: 10.1111/epi.14590. Epub 2018 Oct 28.


Intrahepatic Recurrence Patterns Predict Survival After Resection of Colorectal Liver Metastases.

Lee AJ, Loyer EM, Kang HC, Aloia TA, Tzeng CD, Vauthey JN, Chun YS.

Ann Surg Oncol. 2019 Jan;26(1):275-281. doi: 10.1245/s10434-018-6945-0. Epub 2018 Oct 25.


Safety and tolerability of Korean Red Ginseng in healthy adults: a multicenter, double-blind, randomized, placebo-controlled trial.

Song SW, Kim HN, Shim JY, Yoo BY, Kim DH, Lee SH, Park JS, Kim MJ, Yoo JH, Cho B, Kang HC, Kim KM, Kim SS, Kim KS.

J Ginseng Res. 2018 Oct;42(4):571-576. doi: 10.1016/j.jgr.2018.07.002. Epub 2018 Jul 24.


Licochalcone A attenuates acne symptoms mediated by suppression of NLRP3 inflammasome.

Yang G, Lee HE, Yeon SH, Kang HC, Cho YY, Lee HS, Zouboulis CC, Han SH, Lee JH, Lee JY.

Phytother Res. 2018 Dec;32(12):2551-2559. doi: 10.1002/ptr.6195. Epub 2018 Oct 3.


Regulation of RIP3 protein stability by PELI1-mediated proteasome-dependent degradation.

Park HH, Morgan MJ, Kang HC, Kim YS.

BMB Rep. 2018 Oct;51(10):484-485.


Magnolin targeting of ERK1/2 inhibits cell proliferation and colony growth by induction of cellular senescence in ovarian cancer cells.

Song JH, Lee CJ, An HJ, Yoo SM, Kang HC, Lee JY, Kim KD, Kim DJ, Lee HS, Cho YY.

Mol Carcinog. 2019 Jan;58(1):88-101. doi: 10.1002/mc.22909. Epub 2018 Sep 21.


Effect of dose rate on pulmonary toxicity in patients with hematolymphoid malignancies undergoing total body irradiation.

Kim DY, Kim IH, Yoon SS, Kang HJ, Shin HY, Kang HC.

Radiat Oncol. 2018 Sep 18;13(1):180. doi: 10.1186/s13014-018-1116-9.


BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors.

Koh HY, Kim SH, Jang J, Kim H, Han S, Lim JS, Son G, Choi J, Park BO, Do Heo W, Han J, Lee HJ, Lee D, Kang HC, Shong M, Paik SB, Kim DS, Lee JH.

Nat Med. 2018 Nov;24(11):1662-1668. doi: 10.1038/s41591-018-0172-x. Epub 2018 Sep 17.


Differential feeding by common heterotrophic protists on 12 different Alexandrium species.

Kang HC, Jin Jeong H, So Jin K, You JH, Hee Ok J.

Harmful Algae. 2018 Sep;78:106-117. doi: 10.1016/j.hal.2018.08.005. Epub 2018 Aug 23.


Long-term Outcome of Resective Epilepsy Surgery in Patients With Lennox-Gastaut Syndrome.

Kang JW, Eom S, Hong W, Kwon HE, Park S, Ko A, Kang HC, Lee JS, Lee YM, Kim DS, Kim HD.

Pediatrics. 2018 Oct;142(4). pii: e20180449. doi: 10.1542/peds.2018-0449. Epub 2018 Sep 7.


Mitochondrial-Targeting Anticancer Agent Conjugates and Nanocarrier Systems for Cancer Treatment.

Battogtokh G, Cho YY, Lee JY, Lee HS, Kang HC.

Front Pharmacol. 2018 Aug 17;9:922. doi: 10.3389/fphar.2018.00922. eCollection 2018. Review.


Rufinamide efficacy and safety in children aged 1-4 years with Lennox-Gastaut syndrome.

Kim SH, Kang HC, Lee JS, Kim HD.

Brain Dev. 2018 Nov;40(10):897-903. doi: 10.1016/j.braindev.2018.07.020. Epub 2018 Aug 27.


Targeted siRNA delivery using aptamer-siRNA chimeras and aptamer-conjugated nanoparticles.

Sivakumar P, Kim S, Kang HC, Shim MS.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2019 May;11(3):e1543. doi: 10.1002/wnan.1543. Epub 2018 Aug 2. Review.


The Efficacy of Ketogenic Diet for Specific Genetic Mutation in Developmental and Epileptic Encephalopathy.

Ko A, Jung DE, Kim SH, Kang HC, Lee JS, Lee ST, Choi JR, Kim HD.

Front Neurol. 2018 Jul 16;9:530. doi: 10.3389/fneur.2018.00530. eCollection 2018.


A Novel Reciprocal Crosstalk between RNF168 and PARP1 to Regulate DNA Repair Processes.

Kim JJ, Lee SY, Kim S, Chung JM, Kwon M, Yoon JH, Park S, Hwang Y, Park D, Lee JS, Kang HC.

Mol Cells. 2018 Aug 31;41(8):799-807. doi: 10.14348/molcells.2018.0078. Epub 2018 Jul 24.


Clinical outcomes and prognostic factors in patients with mycosis fungoides who underwent radiation therapy in a single institution.

Jang BS, Kim E, Kim IH, Kang HC, Ye SJ.

Radiat Oncol J. 2018 Jun;36(2):153-162. doi: 10.3857/roj.2017.00542. Epub 2018 Jun 29.

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